Shared genetic influence on frailty and chronic widespread pain: a study from TwinsUK.

abstract：:The overactive bladder is the commonest underlying bladder disorder causing urinary incontinence in elderly people. Management of the condition relies upon a holistic assessment of the problem, lifestyle adjustment, behavioural management and drug therapy. The majority of currently available drugs rely on their anti-m...

journal_title：Age and ageing

authors： Wagg A,Cohen M

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:older people aged 80 and over are increasingly providing end-of-life care to spouses at home and often do so for long periods of time, while also trying to manage their own illnesses and disabilities. Little of the research on older spousal carers has focussed on the oldest carers; hence, the needs of this p...

journal_title：Age and ageing

authors： Turner M,King C,Milligan C,Thomas C,Brearley SG,Seamark D,Wang X,Blake S,Payne S

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:To compare cognitive performance in participants with and without syncope and unexplained falls in a large population representative sample aged 50 years or older. METHODS:Participants of the Irish longitudinal study on ageing (TILDA) were studied. Participants with a history of syncope and/or unexplained fa...

journal_title：Age and ageing

authors： Frewen J,King-Kallimanis B,Boyle G,Kenny RA

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:a fall occurs when an individual experiences a loss of balance from which they are unable to recover. Assessment of balance recovery ability in older adults may therefore help to identify individuals at risk of falls. The purpose of this 12-month prospective study was to assess whether the ability to recover...

journal_title：Age and ageing

authors： Carty CP,Cronin NJ,Nicholson D,Lichtwark GA,Mills PM,Kerr G,Cresswell AG,Barrett RS

更新日期：2015-01-01 00:00:00

abstract：:Genetic factors are known to be of importance in determining the rate of biotransformation of foreign compounds in the liver. Adverse reactions to drugs are increased and pharmacokinetic parameters altered with age. In the present study, the effect of age on plasma paroxonase activity is studied. Paroxonase is a hepat...

journal_title：Age and ageing

authors： Playfer JR,Powell C,Evans DA

更新日期：1977-05-01 00:00:00

abstract：:The effectiveness was compared of 'Classroom' Reality Orientation presented (1) once daily, in groups; (2) twice daily, in groups; and (3) once daily, individually. On a questionnaire measure of orientation all three versions produced significantly greater improvement than that found in an untreated control group, but...

journal_title：Age and ageing

authors： Johnson CH,McLaren SM,McPherson FM

更新日期：1981-02-01 00:00:00

abstract：BACKGROUND:information about the predictors of mortality among the oldest-old is limited. Also possible gender differences are poorly known. OBJECTIVE:to examine the predictors of mortality among individuals aged 90 and older, focusing on differences between men and women. We also analysed gender differences in surviv...

journal_title：Age and ageing

authors： Tiainen K,Luukkaala T,Hervonen A,Jylhä M

更新日期：2013-07-01 00:00:00

abstract：:The aim of the present study was to determine the prevalence of biliary lithiasis (BL) and its major associated factors in the elderly people of a small town in Sicily. All inhabitants over the age of 65 were interviewed and underwent a general physical examination, blood tests and ultrasonography of the gallbladder a...

journal_title：Age and ageing

authors： Montalto G,Soresi M,Carroccio A,Averna MR,Muratore R,Li Castri C,Barbagallo CM,Cavera G,Sapienza M,Notarbartolo A

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:Dementia is a predictor of death and institutionalization. It is less clear if variations in cognition within the normal range predict adverse outcomes. OBJECTIVE:To determine if variation at the high end of cognitive test scores predicts mortality or institutionalization, independent of the effect of poten...

journal_title：Age and ageing

authors： St John PD,Montgomery PR,Kristjansson B,McDowell I

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:There is a paucity of information about the use of antipsychotic medication in long-term care, especially among the oldest-old residents. OBJECTIVE:To analyse the factors associated with the use of antipsychotic medication among nonagenarian residents in long-term institutional care. DESIGN:A retrospective...

journal_title：Age and ageing

authors： Alanen HM,Finne-Soveri H,Noro A,Leinonen E

更新日期：2006-09-01 00:00:00

abstract：:From an international comparison of arm anthropometric reference norms for the elderly a new diagnostic criterion for severe wasting malnutrition was derived: corrected arm muscle area at or below 16.0 cm2 for men or 16.9 cm2 for women. Of 201 consecutive hospital admissions aged 65 years and over, 10 subjects were ma...

journal_title：Age and ageing

authors： Friedman PJ,Campbell AJ,Caradoc-Davies TH

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:Valproate (VPA) is an antiepileptic drug with a broad spectrum of efficacy. Although usually well-tolerated, it may have side-effects of which encephalopathy is one of the most serious. OBJECTIVE:To describe the clinical characteristics of valproate encephalopathy (VE) in five older patients with remote sym...

journal_title：Age and ageing

authors： Beyenburg S,Back C,Diederich N,Lewis M,Reuber M

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVES:to compare walking speed in the UK older population with the speed required to utilise pedestrian crossings (≥1.2 m/s), and determine health and socio-demographic associations with walking impairment. DESIGN:cross-sectional study using Health Survey for England 2005 data. SETTING:private households in Engl...

journal_title：Age and ageing

authors： Asher L,Aresu M,Falaschetti E,Mindell J

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:there are around 100,000 new stroke cases and over a million people living with its consequences annually in the UK. This has large impacts on health and social care, unpaid carers and lost productivity. We aimed to estimate associated costs. METHODS:we estimated 2014/2015 annual mean cost per person and ag...

journal_title：Age and ageing

authors： Patel A,Berdunov V,Quayyum Z,King D,Knapp M,Wittenberg R

更新日期：2020-02-27 00:00:00

abstract：BACKGROUND:Delirium is a complex neuropsychiatric syndrome that is common among elderly inpatients. It has been associated with increased mortality, longer hospital stays, cognitive and functional decline and increased institutionalisation rates. Multicomponent interventions, a series of non-pharmacological strategies ...

journal_title：Age and ageing

authors： Martinez F,Tobar C,Hill N

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:to explore the relationship between blood lipids/lipoproteins and cognitive function in the Chinese oldest-old. DESIGN:multivariate statistical analysis using cross-sectional data. SETTING:community-based setting in longevity areas in China. SUBJECTS:eight hundred and thirty-six subjects aged 80 and older ...

journal_title：Age and ageing

authors： Yin ZX,Shi XM,Kraus VB,Fitzgerald SM,Qian HZ,Xu JW,Zhai Y,Sereny MD,Zeng Y

更新日期：2012-09-01 00:00:00

abstract：:A cross-sectional survey of community-dwelling elderly volunteers (104 women, 87 men, mean age 70 years) was carried out in winter to determine whether cardiovascular and other potentially modifiable lifestyle factors were associated with serum levels of 25-hydroxyvitamin D during this period. Mean winter levels of se...

journal_title：Age and ageing

authors： Scragg R,Khaw KT,Murphy S

更新日期：1995-07-01 00:00:00

abstract：:Alcohol consumption constitutes a substantial burden of disease. Older people are being admitted to hospital for alcohol problems in increasing numbers. A recent systematic review reports cautious supportive evidence for primary prevention interventions in reducing excessive alcohol consumption in older drinkers, but ...

journal_title：Age and ageing

authors： Crome IB,Crome P

更新日期：2018-03-01 00:00:00

abstract：Background:screening for cognitive impairment in Emergency Department (ED) requires short, reliable tools. Objective:to validate the 4AT and 6-Item Cognitive Impairment Test (6-CIT) for ED dementia and delirium screening. Design:diagnostic accuracy study. Setting/subjects:attendees aged ≥70 years in a tertiary care ...

journal_title：Age and ageing

authors： O'Sullivan D,Brady N,Manning E,O'Shea E,O'Grady S,O 'Regan N,Timmons S

更新日期：2018-01-01 00:00:00

abstract：:Lower urinary tract symptoms are frequency report in Parkinson's disease. Whether these are causally related to Parkinson's disease rather than the known effects of age on the urinary tract is unknown. In this study we compared urodynamic data from 1864 women and 357 men with no neurological disease with data from 34 ...

journal_title：Age and ageing

authors： Gray R,Stern G,Malone-Lee J

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:frequent emergency department (ED) attendance at the end of life disrupts care continuity and contradicts most patients' preference for home-based care. OBJECTIVE:to examine factors associated with frequent (≥3) end of life ED attendances among older people to identify opportunities to improve care. METHOD...

journal_title：Age and ageing

authors： Bone AE,Evans CJ,Henson LA,Gao W,Higginson IJ,BUILDCARE study.

更新日期：2019-09-01 00:00:00

abstract：CASE REPORTS:We report three cases of rectus sheath haematoma in elderly women. This condition is commonly misdiagnosed at any age but is an even more elusive diagnosis in elderly patients. CONCLUSION:It is important to consider rectus sheath haematoma in older patients with an abdominal or pelvic mass or spontaneous ...

journal_title：Age and ageing

authors： Bene J,Lassman D,Solomon SA

更新日期：1998-07-01 00:00:00

abstract：OBJECTIVE:To evaluate whether older patients with pyogenic liver abscess have distinctive presenting features or if their management differs from that of younger patients. DESIGN:Retrospective chart review of all cases occurring from 1982 to 1992. SETTING:A regional trauma centre and two large community hospitals. P...

journal_title：Age and ageing

authors： Smoger SH,Mitchell CK,McClave SA

更新日期：1998-07-01 00:00:00

abstract：PURPOSE:Screening tool of older people's prescriptions (STOPP) and screening tool to alert to right treatment (START) criteria were first published in 2008. Due to an expanding therapeutics evidence base, updating of the criteria was required. METHODS:We reviewed the 2008 STOPP/START criteria to add new evidence-based...

journal_title：Age and ageing

authors： O'Mahony D,O'Sullivan D,Byrne S,O'Connor MN,Ryan C,Gallagher P

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:oropharyngeal dysphagia is a common condition among the elderly but not systematically explored. OBJECTIVE:to assess the prevalence and the prognostic significance of oropharyngeal dysphagia among elderly patients with pneumonia. DESIGN:a prospective cohort study. SETTING:an acute geriatric unit in a gene...

journal_title：Age and ageing

authors： Cabre M,Serra-Prat M,Palomera E,Almirall J,Pallares R,Clavé P

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:Patients with Parkinson's disease (PD) are not routinely prescribed bone-protecting medication despite the fact that they are known to be at risk of falling. We investigated whether subjects with PD were more at risk of fractures than other patient groups in order to establish whether preventative measures...

journal_title：Age and ageing

authors： Genever RW,Downes TW,Medcalf P

更新日期：2005-01-01 00:00:00

abstract：:Of 1042 individuals aged 65 years and over who were successfully interviewed in a community survey of health and physical activity, 35% (n = 356) reported one or more falls in the preceding year. Although the overall ratio of female fallers to male fallers was 2.7:1, this ratio approached unity with advancing age. Mob...

journal_title：Age and ageing

authors： Blake AJ,Morgan K,Bendall MJ,Dallosso H,Ebrahim SB,Arie TH,Fentem PH,Bassey EJ

更新日期：1988-11-01 00:00:00

abstract：OBJECTIVES:The objectives of this study were to (i) survey the risk factors for NSAID gastropathy in outpatients (elderly patients in the community), compared to those living in old people's homes or nursing homes, (ii) study the prescription of medication prophylaxis during use of NSAIDs conform the current national g...

journal_title：Age and ageing

authors： van Leen MW,van der Eijk I,Schols JM

更新日期：2007-07-01 00:00:00

abstract：CASE REPORT:An elderly woman with poor nutritional intake developed profound hypophosphataemia and hypokalaemia following the institution of nasogastric feeding. DISCUSSION:Refeeding syndrome is well recognized in certain undernourished groups of patients, but may not be so well known to physicians looking after elder...

journal_title：Age and ageing

authors： Mallet M

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Care management and assessment of need are the cornerstones of the community care reforms in the UK. Although much of the research base has been on highly vulnerable older people, in practice, care management has been implemented for a wider group. OBJECTIVE:To examine how intensive care-management at home ...

journal_title：Age and ageing

authors： Challis D,Darton R,Hughes J,Stewart K,Weiner K

更新日期：2001-09-01 00:00:00