The elimination half-life of benzodiazepines and fall risk: two prospective observational studies.

abstract：:A double-blind, placebo-controlled, clinical study was performed to assess the effects of oral betahistine hydrochloride (Serc) on mental impairment and physical disability in patients with established cerebrovascular disease. Fifty-three patients were admitted to the study during 18 months. Forty-five patients comple...

journal_title：Age and ageing

authors： Pathy J,Menon G,Reynolds A,Van Strik R

更新日期：1977-08-01 00:00:00

abstract：PURPOSE:health-related quality of life (HRQOL) is an important psycho-social characteristic which may impact an individual's ability to manage their chronic disease. We examined the association between HRQOL and antihypertensive medication adherence in older adults. METHODS:participants were part of a cohort study of ...

journal_title：Age and ageing

authors： Holt EW,Muntner P,Joyce CJ,Webber L,Krousel-Wood MA

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Some patients may have medication-related risk factors only identified by home visits, but the extent to which those risk factors are associated with poor health outcomes remains unclear. OBJECTIVE:To determine the association between medication-related risk factors and poor patient health outcomes from obs...

journal_title：Age and ageing

authors： Sorensen L,Stokes JA,Purdie DM,Woodward M,Roberts MS

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:in 2007, the National Patient Safety Agency (NPSA) published 'Slips trips and falls in hospital' and 'Using bedrails safely and effectively'. OBJECTIVES:this observational study aimed to identify changes in local policies in hospitals in England and Wales following these publications. METHOD:policies in pl...

journal_title：Age and ageing

authors： Healey F,Treml J

更新日期：2013-01-01 00:00:00

abstract：:Fifty-eight elderly hospital patients walked along a 10-m length of carpeted corridor and a 10-m length of vinyl-tiled corridor. Gait speed and step length were significantly greater on the carpeted than on the vinyl surface. ...

journal_title：Age and ageing

authors： Willmott M

更新日期：1986-03-01 00:00:00

abstract：OBJECTIVES:to analyse socio-demographic differences in the onset and progression of disability. DESIGN:analysis of a cohort of people aged 55-69 in 1988-9 and in 1994. SUBJECTS:a representative sample of 3543 adults. METHODS:we measured severity of disability at baseline and follow-up. We analysed variations in inci...

journal_title：Age and ageing

authors： Grundy E,Glaser K

更新日期：2000-03-01 00:00:00

abstract：:The course of Motor Neurone Disease (MND) is described in 22 patients in respect of the extent and duration of the disabilities. The average stay in hospital in the terminal phase in 20 patients followed to the time of their death was 6.6 months for men and 4.7 months for women. The total duration of the disease range...

journal_title：Age and ageing

authors： Rosin AJ

更新日期：1976-02-01 00:00:00

abstract：:Bone's mechanical competence and its fragility in particular depend to a certain extent on the structure and microstructure of the cortical bone compartment. Beyond bone mineral density (BMD) and bone mineral content, a variety of other features of cortical bone contribute to whole bone's resistance to fracture. Struc...

journal_title：Age and ageing

authors： Augat P,Schorlemmer S

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Hypertension is a risk factor for both cardiovascular and cerebrovascular disease, with an increasing incidence with advancing patient age. Exercise interventions have the potential to reduce blood pressure in older adults, however, rates of exercise uptake and adherence are low, with 'lack of time' a common...

journal_title：Age and ageing

authors： Herrod PJJ,Lund JN,Phillips BE

更新日期：2020-10-17 00:00:00

abstract：:Twenty digitalized elderly patients with chronic atrial fibrillation were randomized into a double-blind cross-over study. None was in overt heart failure and all were taking < 80 mg frusemide daily. They received xamoterol 200 mg b.d. for 2 months with their usual dose of digoxin for 1 month and placebo digoxin for t...

journal_title：Age and ageing

authors： Lawson-Matthew PJ,McLean KA,Dent M,Austin CA,Channer KS

更新日期：1995-07-01 00:00:00

abstract：:A study was carried out to examine the prevalence of oropharyngeal and urinary tract colonization and to compare the colonizing bacteria with the strains causing nosocomial infections during patients' stays in a geriatric ward. Colonization with Gram-negative rods was not uncommon. Nosocomial infections frequently occ...

journal_title：Age and ageing

authors： Michielsen W,Vandevondele D,Verschraegen G,Claeys G,Afschrift M

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:Frailty is increasingly used to risk stratify older people, but across specialised services there is no standardised approach. The aim of this study was to assess if the Hospital Frailty Risk Score (HFRS) could describe outcomes for older people within English specialised services. DESIGN:A retrospective co...

journal_title：Age and ageing

authors： Imam T,Konstant-Hambling R,Fluck R,Hall N,Palmer J,Conroy S

更新日期：2020-09-08 00:00:00

abstract：:Inappropriate prescribing (IP) is a common and serious global healthcare problem in elderly people, leading to increased risk of adverse drug reactions (ADRs), polypharmacy being the main risk factor for both IP and ADRs. IP in older people is highly prevalent but preventable; hence screening tools for IP have been de...

journal_title：Age and ageing

authors： O'Mahony D,Gallagher PF

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:to evaluate a nurse-led management plan and care pathway for older people discharged from an Accident and Emergency Department after a fall. DESIGN:randomized controlled trial. SETTING:a large teaching hospital. SUBJECTS:348 consecutive patients aged 65 or over attending the Accident and Emergency Departme...

journal_title：Age and ageing

authors： Lightbody E,Watkins C,Leathley M,Sharma A,Lye M

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVE:to examine the association of physical activity and cardio-respiratory fitness with dehydroepiandrosterone sulphate (DHEAS), insulin-like growth factor I (IGF-I) and testosterone in healthy elderly people. DESIGN:cross-sectional study. SETTING:university research department and department of geriatric medic...

journal_title：Age and ageing

authors： Bonnefoy M,Kostka T,Patricot MC,Berthouze SE,Mathian B,Lacour JR

更新日期：1998-11-01 00:00:00

abstract：Background:orthostatic hypotension (OH) is a common disabling condition associated with increased morbidity and mortality. Much of the evidence available is derived from younger populations with chronic neurological disease leading to uncertainty for the diagnosis and management of older people. Objective:to provide a...

journal_title：Age and ageing

authors： Frith J,Parry SW

更新日期：2017-03-01 00:00:00

abstract：Objective:to describe differences in care and 30-day mortality of patients admitted with hip fracture on weekends (Saturday-Sunday) compared to weekdays (Monday-Friday), and their relationship to the organisation of care. Methods:data came from the National Hip Fracture Database (NHFD) linked to ONS mortality data on ...

journal_title：Age and ageing

authors： Neuburger J,Currie C,Wakeman R,Georghiou T,Boulton C,Johansen A,Tsang C,Wilson H,Cromwell DA,van der Meulen J

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVE:to examine the relationships between impairments in hearing and vision and mortality from all-causes and cardiovascular disease (CVD) among older people. DESIGN:population-based cohort study. PARTICIPANTS:the study population included 4,926 Icelandic individuals, aged ≥67 years, 43.4% male, who completed vi...

journal_title：Age and ageing

authors： Fisher D,Li CM,Chiu MS,Themann CL,Petersen H,Jónasson F,Jónsson PV,Sverrisdottir JE,Garcia M,Harris TB,Launer LJ,Eiriksdottir G,Gudnason V,Hoffman HJ,Cotch MF

更新日期：2014-01-01 00:00:00

abstract：:The plasma concentration of beta-thromboglobulin was estimated in elderly in-patients using a radio-immuno-assay technique. There were highly significance differences between the mean values of patients with arterial or venous thrombosis, as compared with controls. The ability of the test to detect thrombosis above th...

journal_title：Age and ageing

authors： Denham MJ,Fisher M,James G,Hassan M,Hodkinson HM

更新日期：1979-02-01 00:00:00

abstract：INTRODUCTION:a professional man sustained a residual, persisting, isolated impairment of short-term memory secondary to severe carbon monoxide poisoning. Informal, open trial of the cholinesterase inhibitor donepezil resulted in uncertain benefit. PROTOCOL:an N-of-1 randomized, double-blind controlled trial of donepez...

journal_title：Age and ageing

authors： Price JD,Grimley Evans J

更新日期：2002-07-01 00:00:00

abstract：:Recent studies have shown a defect in the cholinergic system of the cerebral cortex of patients suffering from nonvascular senile dementia. This observation suggests the possibility of instituting some kind of replacement therapy and trial have been carried out. At this juncture it seem pertinent to ask what lessons c...

journal_title：Age and ageing

authors： Kendall MJ

更新日期：1979-05-01 00:00:00

abstract：BACKGROUND:the terminal decline hypothesis suggests an acceleration in the rate of loss of cognitive function before death. Evidence about the association of educational attainment and the onset of terminal decline is scarce. OBJECTIVE:to investigate the association of education with the onset of terminal decline in g...

journal_title：Age and ageing

authors： Terrera GM,Minett T,Brayne C,Matthews FE

更新日期：2014-01-01 00:00:00

abstract：Objective:To establish a consensus on the care and professional development needs of registered nurses (RNs) employed by UK care homes. Design:Two-stage, online modified Delphi study. Setting and Participants:A panel (n = 352) of individuals with experience, expertise or interest in care home nursing: (i) care home n...

journal_title：Age and ageing

authors： Cooper E,Spilsbury K,McCaughan D,Thompson C,Butterworth T,Hanratty B

更新日期：2017-01-08 00:00:00

abstract：:Among 352 residents of a home for the elderly, who were fully mobile and devoid of most predisposing factors for bacteriuria, 19% of men and 27% of women had two positive cultures within two months. Positive conversion at one year among men and women negative at entry was 11% and 23% respectively, negative conversion ...

journal_title：Age and ageing

authors： Kasviki-Charvati P,Drolette-Kefakis B,Papanayiotou PC,Dontas AS

更新日期：1982-08-01 00:00:00

abstract：:This paper describes how a sample of elderly people were identified from the electoral register using an initial postal screen, and reports a technique that was used to increase the response to the screen. ...

journal_title：Age and ageing

authors： Cartwright A,Smith C

更新日期：1987-03-01 00:00:00

abstract：OBJECTIVES:to measure sex differences in the risk of receiving potentially inappropriate prescription drugs and to examine what are the factors that contribute to these differences. DESIGN:a retrospective cohort study. SETTING:community setting of British Columbia, Canada. PARTICIPANTS:residents of British Columbia ...

journal_title：Age and ageing

authors： Morgan SG,Weymann D,Pratt B,Smolina K,Gladstone EJ,Raymond C,Mintzes B

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:exercise therapy is highly recommended for falls prevention in older adults; however, poor exercise adherence may limit treatment effectiveness. OBJECTIVE:to assess the effectiveness of interventions to improve exercise adherence for community-dwelling adults (aged over 65 years), at risk of falling. METHO...

journal_title：Age and ageing

authors： Hughes KJ,Salmon N,Galvin R,Casey B,Clifford AM

更新日期：2019-03-01 00:00:00

abstract：:Japan is a super-ageing society that faces pressures on its aged care system from a growing population of older adults. Naturalistic observations were undertaken at eight aged care facilities in central and northern Japan to explore how aged care is configured. Four aspects of contemporary provision were identified th...

journal_title：Age and ageing

authors： Annear MJ,Otani J,Sun J

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVES:to compare the cost effectiveness of post-acute care for older people provided in community hospitals with general hospital care. DESIGN:cost-effectiveness study embedded within a randomised controlled trial. SETTING:seven community hospitals and five general hospitals at five centres in the midlands and n...

journal_title：Age and ageing

authors： O'Reilly J,Lowson K,Green J,Young JB,Forster A

更新日期：2008-09-01 00:00:00

abstract：Background:harmful alcohol consumption is reported to be increasing in older people. To intervene and reduce associated risks, evidence currently available needs to be identified. Methods:two systematic reviews in older populations (55+ years): (1) Interventions to prevent or reduce excessive alcohol consumption; (2) ...

journal_title：Age and ageing

authors： Kelly S,Olanrewaju O,Cowan A,Brayne C,Lafortune L

更新日期：2018-03-01 00:00:00