Inappropriate prescribing in the older population: need for new criteria.

abstract：OBJECTIVE:to assess whether incident mobility disability and neighbourhood deprivation in older people are associated independent of the effects of individual socio-economic status, health behaviours and health status. METHODS:prospective cohort study with a 2-year follow-up. SETTING:the English Longitudinal Study of...

journal_title：Age and ageing

authors： Lang IA,Llewellyn DJ,Langa KM,Wallace RB,Melzer D

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:delirium is a clinical syndrome associated with multiple short and long-term complications and therefore prevention is an essential part of its management. This study was designed to assess the efficacy of multicomponent intervention in delirium prevention. METHODS:a total of 287 hospitalised patients at in...

journal_title：Age and ageing

authors： Martinez FT,Tobar C,Beddings CI,Vallejo G,Fuentes P

更新日期：2012-09-01 00:00:00

abstract：:Of 60 patients referred for geriatric assessment with clinically significant hypochromic anaemia, in the absence of frank bleeding, 44 underwent upper gastrointestinal and 27 lower gastrointestinal investigations. The probability of identifying a potential cause at upper gastrointestinal endoscopy was three times that...

journal_title：Age and ageing

authors： Calvey HD,Castleden CM

更新日期：1987-11-01 00:00:00

abstract：:The effectiveness was compared of 'Classroom' Reality Orientation presented (1) once daily, in groups; (2) twice daily, in groups; and (3) once daily, individually. On a questionnaire measure of orientation all three versions produced significantly greater improvement than that found in an untreated control group, but...

journal_title：Age and ageing

authors： Johnson CH,McLaren SM,McPherson FM

更新日期：1981-02-01 00:00:00

abstract：:Pulmonary embolism (PE) is a potentially severe diagnosis with high short-term mortality. Recently, age-adjusted cut-off values (age × 10 μg/l) of D-dimer were introduced to improve the diagnostic workup in older patients. In clinical practice, PE is considered 'ruled out' in patients with a non-high clinical probabil...

journal_title：Age and ageing

authors： Stein CE,Keijsers CJ,Bootsma JE,Schouten HJ

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVES:to investigate the effectiveness of a pharmacy discharge plan in elderly hospitalized patients. DESIGN:randomized controlled trial. SUBJECTS AND SETTINGS:we randomized patients aged 75 years and older on four or more medicines who had been discharged from three acute general and one long-stay hospital to a...

journal_title：Age and ageing

authors： Nazareth I,Burton A,Shulman S,Smith P,Haines A,Timberal H

更新日期：2001-01-01 00:00:00

abstract：Background:despite an increasing proportion of older people working beyond State Pension Age (SPA), little is known about neither the motivations for this decision nor whether, and to what extent, working beyond SPA affects quality of life (QoL). Methods:QoL was measured using the CASP-19 scale. Respondents in paid wo...

journal_title：Age and ageing

authors： Di Gessa G,Corna L,Price D,Glaser K

更新日期：2018-05-01 00:00:00

abstract：Background:pain is prevalent in frail older adults; however, the association of pain and frailty has not been evaluated yet by a systematic assessment of prospective longitudinal studies. Objective:we aimed to assess the association of persistent pain as a risk factor for frailty incidence, using data from longitudina...

journal_title：Age and ageing

authors： Saraiva MD,Suzuki GS,Lin SM,de Andrade DC,Jacob-Filho W,Suemoto CK

更新日期：2018-11-01 00:00:00

abstract：Objective:to investigate a high-intensity functional exercise (HIFE) group in hospitalised older adults. Design:assessor-blinded, randomised-controlled trial. Setting:sub-acute wards at a metropolitan rehabilitation hospital. Participants:older adults ≥65 years (n = 468) able to stand with minimum assistance or less...

journal_title：Age and ageing

authors： Raymond MJ,Jeffs KJ,Winter A,Soh SE,Hunter P,Holland AE

更新日期：2017-03-01 00:00:00

abstract：:Orthostatic hypotension is a common problem in older adults and can be associated with falls, dizziness and syncope and their associated consequences. Therefore, it is important to recognise the condition and institute appropriate management. We report an elderly woman who presented with orthostatic hypotension and wa...

journal_title：Age and ageing

authors： Bragg F,Kumar NP

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:chronic knee pain is still considered a fairly benign disease by many, an 'unavoidable' consequence of ageing. This passive acceptance may be unnecessarily exposing older people to disability and serious co-morbidity. The aim of this study was to determine the disease burden associated with chronic knee pain...

journal_title：Age and ageing

authors： Fransen M,Su S,Harmer A,Blyth FM,Naganathan V,Sambrook P,Le Couteur D,Cumming RG

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:physical and mental health are important risk factors for cardiovascular disease (CVD) incidence and death among postmenopausal women. The objective of this study was to assess whether changes in physical and mental health were associated with CVD incidence and death. METHODS:in the Women's Health Initiativ...

journal_title：Age and ageing

authors： Saquib N,Brunner R,Desai M,Kroenke C,Martin LW,Daviglus M,Allen NB,Robinson J,Tindle H,Stefanick ML

更新日期：2019-05-01 00:00:00

abstract：:Postural control is no longer considered simply a summation of static reflexes but, rather, a complex skill based on the interaction of dynamic sensorimotor processes. The two main functional goals of postural behaviour are postural orientation and postural equilibrium. Postural orientation involves the active alignme...

journal_title：Age and ageing

authors： Horak FB

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:COVID-19 has disproportionately affected older people. OBJECTIVE:The objective of this paper to investigate whether frailty is associated with all-cause mortality in older hospital inpatients, with COVID-19. DESIGN:Cohort study. SETTING:Secondary care acute hospital. PARTICIPANTS:Participants included ar...

journal_title：Age and ageing

authors： Aw D,Woodrow L,Ogliari G,Harwood R

更新日期：2020-10-23 00:00:00

abstract：BACKGROUND:the 16-item Falls Efficacy Scale-International (FES-I) has been shown to have excellent reliability and construct validity. However, for practical and clinical purposes, a shortened version of the FES-I would be useful. OBJECTIVE:to develop and validate a shortened version of FES-I while preserving good psy...

journal_title：Age and ageing

authors： Kempen GI,Yardley L,van Haastregt JC,Zijlstra GA,Beyer N,Hauer K,Todd C

更新日期：2008-01-01 00:00:00

abstract：:Sleep disordered breathing (SDB) may be associated with cognitive dysfunction in non-demented elderly people. A random sample of 96 retirement village residents were given both neuropsychological assessment and overnight sleep monitoring with a portable microprocessor based system (Vitalog PMS-8). Respiratory disturba...

journal_title：Age and ageing

authors： Hayward L,Mant A,Eyland A,Hewitt H,Purcell C,Turner J,Goode E,Le Count A,Pond D,Saunders N

更新日期：1992-03-01 00:00:00

abstract：:We analysed 103 episodes of upper gastrointestinal bleeding in 88 elderly patients (age 76 +/- 7.7 years) to determine which of a group of 52 clinical and laboratory variables, measured on admission, best predicted continued or rebleeding, and death in these patients. Variables which related directly to the size of th...

journal_title：Age and ageing

authors： Booker JA,Johnston M,Booker CI,Tydd T,Mitchell R

更新日期：1987-07-01 00:00:00

abstract：:In the population study Seventy-year-old People in Göteborg, 449 70-year-old men were examined in 1971/72. Out of these, 331 were re-examined in 1976/77 at age 75, together with a cohort-comparison group of 474 70-year-old men. Cohort differences and a lower smoking prevalence at higher ages were observed. The loss of...

journal_title：Age and ageing

authors： Mellström D,Rundgren A,Jagenburg R,Steen B,Svanborg A

更新日期：1982-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:the data concerning the predictive role of oxidised LDL (ox-LDL) in all-cause mortality are scarce. We investigated whether circulating ox-LDL would stand out as a risk factor of total mortality in the elderly. Study subjects, design and methods: a total of 1,260 elderly inhabitants (533 men, 7...

journal_title：Age and ageing

authors： Linna M,Ahotupa M,Löppönen MK,Irjala K,Vasankari T

更新日期：2013-01-01 00:00:00

abstract：Background:overactive bladder (OAB) is a common condition in older persons. Antimuscarinic treatment remains the mainstay of treatment of OAB but clinicians have been reluctant to prescribe this to older patients. This study examined efficacy and safety information from patients >65 in fesoterodine trials to reaffirm e...

journal_title：Age and ageing

authors： Wagg A,Arumi D,Herschorn S,Angulo Cuesta J,Haab F,Ntanios F,Carlsson M,Oelke M

更新日期：2017-07-01 00:00:00

abstract：:The number of older people living with human immunodeficiency virus (HIV) in the UK is rising. Older people are at risk of acquiring HIV infection for a multitude of reasons. This, combined with effective HIV treatment which has significantly prolonged life expectancy, means that health care professionals working in t...

journal_title：Age and ageing

authors： Pratt G,Gascoyne K,Cunningham K,Tunbridge A

更新日期：2010-05-01 00:00:00

abstract：:A study was carried out to examine the prevalence of oropharyngeal and urinary tract colonization and to compare the colonizing bacteria with the strains causing nosocomial infections during patients' stays in a geriatric ward. Colonization with Gram-negative rods was not uncommon. Nosocomial infections frequently occ...

journal_title：Age and ageing

authors： Michielsen W,Vandevondele D,Verschraegen G,Claeys G,Afschrift M

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:arterial stiffening is a marker of vascular ageing and an independent risk factor for cardiovascular disease. A potential mechanism linking cardiovascular disease to chronic kidney disease might be the change in arterial elasticity. We aim to determine the association between renal function and arterial stif...

journal_title：Age and ageing

authors： Sedaghat S,Dawkins Arce FG,Verwoert GC,Hofman A,Ikram MA,Franco OH,Dehghan A,Witteman JC,Mattace-Raso F

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:The long-term effectiveness of group continence promotion delivered via community organisations on female urinary incontinence, falls and healthy life expectancy remains unknown. METHODS:A pragmatic cluster randomised trial was conducted among 909 women aged 65-98 years with urinary incontinence, recruited ...

journal_title：Age and ageing

authors： Tannenbaum C,Fritel X,Halme A,van den Heuvel E,Jutai J,Wagg A

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:the empirical Dignity Model has profoundly influenced the provision of palliative care for older terminally ill patients in the West, as it provides practical guidance and intervention strategies for promoting dignity and reducing distress at the end-of-life. OBJECTIVE:to examine the concept of 'living and ...

journal_title：Age and ageing

authors： Ho AH,Chan CL,Leung PP,Chochinov HM,Neimeyer RA,Pang SM,Tse DM

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:animal studies suggest a neuroprotective role for leptin, but human studies have shown mixed results. We examined whether plasma leptin levels in individuals with mild cognitive impairment (MCI) were related to cognitive function at baseline and whether higher leptin levels were associated with reduced risk ...

journal_title：Age and ageing

authors： Oania R,McEvoy LK

更新日期：2015-01-01 00:00:00

abstract：:Plasma Human Growth Hormone (HGH) was raised in a patient with bronchial carcinoma and hypertrophic pulmonary osteoarthropathy before radiotherapy to the tumour. Though the soft-tissue swelling and pain of hypertrophic osteoarthropathy disappeared two to three weeks after radiotherapy to the carcinoma the HGH plasma l...

journal_title：Age and ageing

authors： Mukherjee SK

更新日期：1975-05-01 00:00:00

abstract：PURPOSE:health-related quality of life (HRQOL) is an important psycho-social characteristic which may impact an individual's ability to manage their chronic disease. We examined the association between HRQOL and antihypertensive medication adherence in older adults. METHODS:participants were part of a cohort study of ...

journal_title：Age and ageing

authors： Holt EW,Muntner P,Joyce CJ,Webber L,Krousel-Wood MA

更新日期：2010-07-01 00:00:00

abstract：:The contribution of the elderly to the workload of a combined consultative District Hospital Gastroenterology Clinic has been studied over a 12-year period. The elderly group comprise 24% of the total referrals with a gradually increasing trend over successive years. The service implications are discussed and the main...

journal_title：Age and ageing

authors： Purkayastha SK,Salter RH,Holmes KM

更新日期：1988-01-01 00:00:00

abstract：CASE REPORT:An elderly woman with poor nutritional intake developed profound hypophosphataemia and hypokalaemia following the institution of nasogastric feeding. DISCUSSION:Refeeding syndrome is well recognized in certain undernourished groups of patients, but may not be so well known to physicians looking after elder...

journal_title：Age and ageing

authors： Mallet M

更新日期：2002-01-01 00:00:00