Potentially inappropriate prescribing in older residents in Irish nursing homes.

abstract：OBJECTIVE:to examine the relationships between impairments in hearing and vision and mortality from all-causes and cardiovascular disease (CVD) among older people. DESIGN:population-based cohort study. PARTICIPANTS:the study population included 4,926 Icelandic individuals, aged ≥67 years, 43.4% male, who completed vi...

journal_title：Age and ageing

authors： Fisher D,Li CM,Chiu MS,Themann CL,Petersen H,Jónasson F,Jónsson PV,Sverrisdottir JE,Garcia M,Harris TB,Launer LJ,Eiriksdottir G,Gudnason V,Hoffman HJ,Cotch MF

更新日期：2014-01-01 00:00:00

abstract：:Clinical observations suggest an age-associated decline in skin perfusion but there are few quantitative in vivo data on skin perfusion at various ages. We studied skin perfusion of the dorsum of the foot by determining the capillary blood flow velocity (CBFV) expressed in millivolts (mV), using laser Doppler flowmetr...

journal_title：Age and ageing

authors： Weiss M,Milman B,Rosen B,Eisenstein Z,Zimlichman R

更新日期：1992-07-01 00:00:00

abstract：Background:diabetes increases the risk of frailty that is a leading cause of disability and premature mortality in older people. Metabolic syndrome (MS) and insulin resistance (IR) are strong risk factors for diabetes and could, thus, lead to frailty. However, the association between MS or IR and frailty has barely bee...

journal_title：Age and ageing

authors： Pérez-Tasigchana RF,León-Muñoz LM,Lopez-Garcia E,Gutierrez-Fisac JL,Laclaustra M,Rodríguez-Artalejo F,Guallar-Castillón P

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:to determine the prevalence of vertebral fractures and their risk factors in geriatric patients. DESIGN:prospective cohort study. SETTING:teaching hospital in Amsterdam, The Netherlands. SUBJECTS:three hundred and three geriatric patients, who had their first visit at a diagnostic day hospital between Apr...

journal_title：Age and ageing

authors： van der Jagt-Willems HC,van Hengel M,Vis M,van Munster BC,van Campen JP,Tulner LR,Lems WF

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:prevalence estimates for chronic diseases and associated risk factors are needed for priority setting and disease prevention strategies. The aim of this cross-sectional study was to estimate the self-reported and clinical prevalence of common chronic disorders in elderly men. STUDY DESIGN AND SETTING:a quest...

journal_title：Age and ageing

authors： Frost M,Wraae K,Gudex C,Nielsen T,Brixen K,Hagen C,Andersen M

更新日期：2012-03-01 00:00:00

abstract：INTRODUCTION:observational studies do not always find positive associations between physical activity and muscle strength despite intervention studies consistently showing that exercise improves strength in older adults. In previous analyses of the MRC National Survey of Health and Development (NSHD), the 1946 British ...

journal_title：Age and ageing

authors： Dodds R,Kuh D,Aihie Sayer A,Cooper R

更新日期：2013-11-01 00:00:00

abstract：:At present, frailty is defined variably. Some consensus on a definition is likely to emerge, but the basis for a successful definition needs to be explored. Here, a classic approach to validation is proposed: a successful definition of frailty should be multifactorial but must also manage the many factors in a way tha...

journal_title：Age and ageing

authors： Rockwood K

更新日期：2005-09-01 00:00:00

abstract：:Fat necrosis of the breast is a well-recognised complication of unfractionated heparin. The following is a case of fat necrosis due to low-molecular-weight heparin in a 91-year-old woman admitted to hospital with unstable angina. ...

journal_title：Age and ageing

authors： Das AK

更新日期：2005-03-01 00:00:00

abstract：PRESENTATION:a previously fit 80-year-old woman presented with a 2-week history of spontaneous and extensive bruising affecting all four limbs. The severity was such that she required a transfusion of 8 units of blood. RESULTS OF INVESTIGATIONS:a markedly prolonged activated partial thromboplastin time which was only ...

journal_title：Age and ageing

authors： Kelly J,Gattens M,Geraghty R

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The very old are expected to become a growing part of the stroke population in the industrialised part of the world. The aims of this study were to evaluate clinical characteristics of patients aged 85 years or more at stroke onset and to investigate very old age as an independent predictor of sh...

journal_title：Age and ageing

authors： Kammersgaard LP,Jørgensen HS,Reith J,Nakayama H,Pedersen PM,Olsen TS,Copenhagen Stroke Study.

更新日期：2004-03-01 00:00:00

abstract：:An outline is given of simple urodynamic investigations applicable to elderly subjects. The type of patient presenting primarily to geriatric departments with urinary incontinence, whose management is aided by such studies, is described under various clinical groupings. The requirement for urodynamic studies and the b...

journal_title：Age and ageing

authors： Eastwood HD

更新日期：1979-02-01 00:00:00

abstract：:Interleukin-1 mediates the febrile response which is often said to be reduced in the elderly. Interleukin-1 production by monocytes cultured in vitro and stimulated with bacterial lipopolysaccharide was measured. Three groups of subjects were studied; 40 normal young, 33 well elderly and 40 elderly with a history of r...

journal_title：Age and ageing

authors： Rudd AG,Banerjee DK

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Dementia is a predictor of death and institutionalization. It is less clear if variations in cognition within the normal range predict adverse outcomes. OBJECTIVE:To determine if variation at the high end of cognitive test scores predicts mortality or institutionalization, independent of the effect of poten...

journal_title：Age and ageing

authors： St John PD,Montgomery PR,Kristjansson B,McDowell I

更新日期：2002-09-01 00:00:00

abstract：:A 73-year-old man presented with a huge intra-abdominal mass. Initially a gastrointestinal stromal tumour (GIST) was diagnosed, but his tumour was subsequently classified as a spindle cell sarcoma. Difficulties in the classification of rare intra-abdominal tumours are discussed. ...

journal_title：Age and ageing

authors： Bills V,Iqbal R,Haqqani M,Clague JE

更新日期：2005-01-01 00:00:00

abstract：Background:harmful alcohol consumption is reported to be increasing in older people. To intervene and reduce associated risks, evidence currently available needs to be identified. Methods:two systematic reviews in older populations (55+ years): (1) Interventions to prevent or reduce excessive alcohol consumption; (2) ...

journal_title：Age and ageing

authors： Kelly S,Olanrewaju O,Cowan A,Brayne C,Lafortune L

更新日期：2018-03-01 00:00:00

abstract：:Twenty-four incontinent elderly institutionalized subjects with detrusor instability participated in a double-blind placebo-controlled trial of oxybutynin chloride. Patients were randomly assigned to oral oxybutynin 5 mg or placebo twice daily. Administration continued for 8 days; a 6-day washout period was followed b...

journal_title：Age and ageing

authors： Zorzitto ML,Holliday PJ,Jewett MA,Herschorn S,Fernie GR

更新日期：1989-05-01 00:00:00

abstract：:Deprescribing has gained interest recently, driven by an ageing population seeing an increasing number living with multiple long-term conditions. This, coupled with disease-specific guidelines derived from clinical trials in younger people, has led to an increase in exposure to polypharmacy and the associated therapeu...

journal_title：Age and ageing

authors： Woodford HJ,Fisher J

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:residential aged care facility (RACF) resident numbers are increasing. Residents are frequently frail with substantial co-morbidity, functional and cognitive impairment with high susceptibility to acute illness. Despite living in facilities staffed by health professionals, a considerable proportion of reside...

journal_title：Age and ageing

authors： Dwyer R,Gabbe B,Stoelwinder JU,Lowthian J

更新日期：2014-11-01 00:00:00

abstract：:Delirium is a common presentation in older inpatients with COVID-19, and a risk factor for cognitive decline at discharge. The glaring gaps in the service provision in delirium care, regardless of aetiology, after a hospital admission pre-existed the pandemic, but the pandemic arguably offers an opportunity now to add...

journal_title：Age and ageing

authors： Rahman S,Byatt K

更新日期：2021-01-22 00:00:00

abstract：BACKGROUND:dysphagia is common following stroke and is associated with the development of pneumonia. Many dysphagia treatment options are available, some still experimental and others already rooted in common practice. Previous reviews of these treatments were limited due to a dearth of available studies. Recently, mor...

journal_title：Age and ageing

authors： Foley N,Teasell R,Salter K,Kruger E,Martino R

更新日期：2008-05-01 00:00:00

abstract：:Falls pose a major threat to the well-being and quality of life of older people. Falls can result in fractures and other injuries, disability and fear and can trigger a decline in physical function and loss of autonomy. This article synthesises recent published findings on fall risk and mobility assessments and fall p...

journal_title：Age and ageing

authors： Lord SR,Close JCT

更新日期：2018-07-01 00:00:00

abstract：:A cross-sectional survey of community-dwelling elderly volunteers (104 women, 87 men, mean age 70 years) was carried out in winter to determine whether cardiovascular and other potentially modifiable lifestyle factors were associated with serum levels of 25-hydroxyvitamin D during this period. Mean winter levels of se...

journal_title：Age and ageing

authors： Scragg R,Khaw KT,Murphy S

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:the Falls Risk for Older People in the Community assessment (FROP-Com) tool was designed for use in targeted multi-factorial falls prevention programmes. It fills the gap between the short screening tools and the longer assessment tools, e.g. the physiological profile assessment (PPA). The aim of this study ...

journal_title：Age and ageing

authors： Russell MA,Hill KD,Blackberry I,Day LM,Dharmage SC

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:to prevent the occurrence of weight loss during hospitalisation and following discharge by daily oral supplementation. DESIGN:in a prospective, randomised, controlled study of 80 patients aged 75 or more, and at risk of undernutrition based on their initial Mini Nutritional Assessment score, patients were ra...

journal_title：Age and ageing

authors： Gazzotti C,Arnaud-Battandier F,Parello M,Farine S,Seidel L,Albert A,Petermans J

更新日期：2003-05-01 00:00:00

abstract：:Plasma Human Growth Hormone (HGH) was raised in a patient with bronchial carcinoma and hypertrophic pulmonary osteoarthropathy before radiotherapy to the tumour. Though the soft-tissue swelling and pain of hypertrophic osteoarthropathy disappeared two to three weeks after radiotherapy to the carcinoma the HGH plasma l...

journal_title：Age and ageing

authors： Mukherjee SK

更新日期：1975-05-01 00:00:00

abstract：OBJECTIVE:an abbreviated form of the Duke Social Support Index (DSSI) as used in a large longitudinal study of older Australian women was examined with respect to factors that might be expected to affect social support for older women over time. METHODS:in this large cohort study two sub-scales of the DSSI, one descri...

journal_title：Age and ageing

authors： Pachana NA,Smith N,Watson M,McLaughlin D,Dobson A

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:the Oxfordshire Community Stroke Project (OCSP) devised a simple clinical classification for acute stroke which predicted mortality, functional recovery and patterns of recurrent stroke. We aimed to determine whether this could predict the presence of carotid disease and be used to select which patients with...

journal_title：Age and ageing

authors： Mead GE,Shingler H,Farrell A,O'Neill PA,McCollum CN

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:age-related differences in the treatment of lung cancer patients have been reported in the past, but most previous studies have not recorded case-mix factors, nor have they studied the impact of such ageism on survival. METHODS:a questionnaire-based study of diagnostic and case-mix factors was carried out a...

journal_title：Age and ageing

authors： Peake MD,Thompson S,Lowe D,Pearson MG,Participating Centres.

更新日期：2003-03-01 00:00:00

abstract：:A double-blind, placebo-controlled, clinical study was performed to assess the effects of oral betahistine hydrochloride (Serc) on mental impairment and physical disability in patients with established cerebrovascular disease. Fifty-three patients were admitted to the study during 18 months. Forty-five patients comple...

journal_title：Age and ageing

authors： Pathy J,Menon G,Reynolds A,Van Strik R

更新日期：1977-08-01 00:00:00

abstract：:A prospective study was carried out on 288 general surgical patients aged 65 years and over. Over 40% of patients suffered no post-operative complication. The commonest post-operative problem was respiratory, with 17% of patients having simple atelectasis, 12% acute bronchitis and 10% pneumonia. Six per cent of patien...

journal_title：Age and ageing

authors： Seymour DG,Vaz FG

更新日期：1989-09-01 00:00:00