Socioeconomic status and the trajectory of self-rated health.

abstract：BACKGROUND:Frailty was shown to be associated with psychosocial risk factors, but there are few longitudinal data. METHODS:We used data from waves 5 and 6 of the Survey of Health Aging Retirement in Europe (SHARE) to study the contribution of loneliness and social isolation to transitions towards frailty defined accor...

journal_title：Age and ageing

authors： Jarach CM,Tettamanti M,Nobili A,D'avanzo B

更新日期：2021-01-08 00:00:00

abstract：:Clinical observations suggest an age-associated decline in skin perfusion but there are few quantitative in vivo data on skin perfusion at various ages. We studied skin perfusion of the dorsum of the foot by determining the capillary blood flow velocity (CBFV) expressed in millivolts (mV), using laser Doppler flowmetr...

journal_title：Age and ageing

authors： Weiss M,Milman B,Rosen B,Eisenstein Z,Zimlichman R

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:the terminal decline hypothesis suggests an acceleration in the rate of loss of cognitive function before death. Evidence about the association of educational attainment and the onset of terminal decline is scarce. OBJECTIVE:to investigate the association of education with the onset of terminal decline in g...

journal_title：Age and ageing

authors： Terrera GM,Minett T,Brayne C,Matthews FE

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:we aimed to investigate the association of smoking cessation with risk of all-cause mortality amongst oldest old people (aged ≥ 80 years). DESIGN:this was a prospective cohort study. SETTING:the Chinese Longitudinal Healthy Longevity Survey, implemented in 23 provinces of China. PARTICIPANTS:a total of 28,...

journal_title：Age and ageing

authors： Wei Y,Lv Y,Zhou J,Gao X,Duan J,Zhao C,Yin Z,Kang Q,Wu B,Chen C,Mao C,Li J,Shi X

更新日期：2021-01-23 00:00:00

abstract：OBJECTIVE:to explore the relationship between blood lipids/lipoproteins and cognitive function in the Chinese oldest-old. DESIGN:multivariate statistical analysis using cross-sectional data. SETTING:community-based setting in longevity areas in China. SUBJECTS:eight hundred and thirty-six subjects aged 80 and older ...

journal_title：Age and ageing

authors： Yin ZX,Shi XM,Kraus VB,Fitzgerald SM,Qian HZ,Xu JW,Zhai Y,Sereny MD,Zeng Y

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Care management and assessment of need are the cornerstones of the community care reforms in the UK. Although much of the research base has been on highly vulnerable older people, in practice, care management has been implemented for a wider group. OBJECTIVE:To examine how intensive care-management at home ...

journal_title：Age and ageing

authors： Challis D,Darton R,Hughes J,Stewart K,Weiner K

更新日期：2001-09-01 00:00:00

abstract：:Mild cognitive impairment (MCI) is a common clinical syndrome that identifies people at high risk of developing dementia. Although treatments for MCI are currently unavailable, preliminary evidence has identified potential neuro-protective effects of physical activity, which may lead to improved outcomes. However, the...

journal_title：Age and ageing

authors： Barber SE,Clegg AP,Young JB

更新日期：2012-01-01 00:00:00

abstract：:In a study of two representative population samples of 70-year-olds, one of which was followed up at 75 years of age, digitalis treatment was associated with oestrogen-like metabolic effects, indicated by changes in the composition of the plasma phospholipid fraction. Digitalis treatment, at least at these ages, is re...

journal_title：Age and ageing

authors： Persson G,Landahl S,Svanborg A

更新日期：1982-11-01 00:00:00

abstract：BACKGROUND:The risk/benefit ratio of warfarin therapy changes in the over 75s, when haemorrhagic side-effects become more common. These may not always be reported in the literature. CASE REPORT:A woman of 80 years, on long-term warfarin therapy presented with an acute dissecting thoracic aortic aneurysm; on investigat...

journal_title：Age and ageing

authors： Blunt DM,Impallomeni MG

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:we evaluated a specialist community-based dementia service to establish whether high quality care was being delivered and the conditions for doing so. The service was in an urban part of Rushcliffe Primary Care Trust, Nottinghamshire, United Kingdom. The service comprised an assessment team of an occupationa...

journal_title：Age and ageing

authors： Gladman JR,Jones RG,Radford K,Walker E,Rothera I

更新日期：2007-03-01 00:00:00

abstract：:To determine whether medication use differs by cognitive status among community dwelling elderly, a survey was made of a stratified random sample of 4110 black and white participants, aged 65 or older from the Duke Established Populations for Epidemiologic Studies of the Elderly in five adjacent urban and rural counti...

journal_title：Age and ageing

authors： Hanlon JT,Landerman LR,Wall WE Jr,Horner RD,Fillenbaum GG,Dawson DV,Schmader KE,Cohen HJ,Blazer DG

更新日期：1996-05-01 00:00:00

abstract：:Explicit criteria, such as the STOPP/START criteria, are increasingly used both in clinical practice and in research to identify potentially inappropriate prescribing in older people. In an article on the STOPP/START criteria version 2, O'Mahony et al have pointed out the advantages of developing computerised criteria...

journal_title：Age and ageing

authors： Anrys P,Boland B,Degryse JM,De Lepeleire J,Petrovic M,Marien S,Dalleur O,Strauven G,Foulon V,Spinewine A

更新日期：2016-09-01 00:00:00

abstract：:Tests of intestinal permeability are used as a reflection of upper-small-intestinal mucosal damage. Thirty-two elderly in-patients aged 75-96 years, and 64 hospital volunteers aged 22-64 years with no overt gastro-intestinal disease were studied to determine whether permeability changes with increasing age. Intestinal...

journal_title：Age and ageing

authors： Saweirs WM,Andrews DJ,Low-Beer TS

更新日期：1985-09-01 00:00:00

abstract：:Investigation of 21 elderly women with a wide range of renal function showed that plasma creatinine concentrations above 100 mumol/l were associated with glomerular filtration rates (GFR) below 50 ml/min. Plasma 1,25-dihydroxyvitamin D concentrations and radio-calcium absorption were directly related to GFR and were l...

journal_title：Age and ageing

authors： Francis RM,Peacock M,Barkworth SA

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:despite the vast literature in the area, few studies examined the large range of factors associated with physical activity (PA) in the older adult collectively, information that could help develop a supportive culture for healthy ageing. OBJECTIVE:to identify the socio-demographic, social connectedness, phy...

journal_title：Age and ageing

authors： McKee G,Kearney PM,Kenny RA

更新日期：2015-07-01 00:00:00

abstract：Background:pain is prevalent in frail older adults; however, the association of pain and frailty has not been evaluated yet by a systematic assessment of prospective longitudinal studies. Objective:we aimed to assess the association of persistent pain as a risk factor for frailty incidence, using data from longitudina...

journal_title：Age and ageing

authors： Saraiva MD,Suzuki GS,Lin SM,de Andrade DC,Jacob-Filho W,Suemoto CK

更新日期：2018-11-01 00:00:00

abstract：:Integrated care programs have been developed to enhance the quality care for older adults in primary care. These programs usually consist of a multidisciplinary approach, with personalised care based on comprehensive geriatric assessments. However, there is limited evidence for the effectiveness of these programs in f...

journal_title：Age and ageing

authors： Hoogendijk EO

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Using Newcastle 85+ Study data, we investigated transitions between frailty states from age 85 to 90 years and whether multi-morbidities and socioeconomic status (SES) modify transitions. METHODS:The Newcastle 85+ Study is a prospective, longitudinal cohort study of all people born in 1921 in Newcastle and ...

journal_title：Age and ageing

authors： Mendonça N,Kingston A,Yadegarfar M,Hanson H,Duncan R,Jagger C,Robinson L

更新日期：2020-10-23 00:00:00

abstract：PURPOSE:health-related quality of life (HRQOL) is an important psycho-social characteristic which may impact an individual's ability to manage their chronic disease. We examined the association between HRQOL and antihypertensive medication adherence in older adults. METHODS:participants were part of a cohort study of ...

journal_title：Age and ageing

authors： Holt EW,Muntner P,Joyce CJ,Webber L,Krousel-Wood MA

更新日期：2010-07-01 00:00:00

abstract：AIM:to determine the positive yield of carotid sinus massage in different patient groups: unexplained syncope, falls, dizziness and controls. DESIGN:observational study. SETTING:teaching hospital. METHODS:we studied consecutive patients over the age of 60 years referred to the 'falls clinic' with a history of unexpl...

journal_title：Age and ageing

authors： Kumar NP,Thomas A,Mudd P,Morris RO,Masud T

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:it is uncertain as to which measures of gait best predict those who are likely to fall. Our aim was to investigate the associations of gait and gait variability measures with incident falls risk. METHODS:individuals aged 60-86 years (n = 412) were randomly selected from the Tasmanian electoral roll. Average...

journal_title：Age and ageing

authors： Callisaya ML,Blizzard L,Schmidt MD,Martin KL,McGinley JL,Sanders LM,Srikanth VK

更新日期：2011-07-01 00:00:00

abstract：Objective:to investigate a high-intensity functional exercise (HIFE) group in hospitalised older adults. Design:assessor-blinded, randomised-controlled trial. Setting:sub-acute wards at a metropolitan rehabilitation hospital. Participants:older adults ≥65 years (n = 468) able to stand with minimum assistance or less...

journal_title：Age and ageing

authors： Raymond MJ,Jeffs KJ,Winter A,Soh SE,Hunter P,Holland AE

更新日期：2017-03-01 00:00:00

abstract：INTRODUCTION:observational studies do not always find positive associations between physical activity and muscle strength despite intervention studies consistently showing that exercise improves strength in older adults. In previous analyses of the MRC National Survey of Health and Development (NSHD), the 1946 British ...

journal_title：Age and ageing

authors： Dodds R,Kuh D,Aihie Sayer A,Cooper R

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:to evaluate the relationship between serum levels of the soluble Receptor for Advanced Glycation End-products (sRAGE) and mortality in frail and non-frail older adults. METHODS:we studied 691 subjects (141 frail and 550 non-frail) with a median age of 75 years from two population-based cohorts, the Toledo St...

journal_title：Age and ageing

authors： Butcher L,Carnicero JA,Gomez Cabrero D,Dartigues JF,Pérès K,Garcia-Garcia FJ,Rodriguez-Mañas L,Erusalimsky JD,FRAILOMIC Consortium.

更新日期：2019-09-01 00:00:00

abstract：:The capacity of peripheral blood mononuclear cells (PBMC) isolated from patients with Alzheimer's disease to produce interleukin-1 and -2 (IL-1, IL-2) was compared to that of cells from age-matched controls and young healthy subjects. There was no difference in the production of both interleukins between patients and ...

journal_title：Age and ageing

authors： Bessler H,Sirota P,Hart J,Djaldetti M

更新日期：1989-01-01 00:00:00

abstract：:Alcohol consumption constitutes a substantial burden of disease. Older people are being admitted to hospital for alcohol problems in increasing numbers. A recent systematic review reports cautious supportive evidence for primary prevention interventions in reducing excessive alcohol consumption in older drinkers, but ...

journal_title：Age and ageing

authors： Crome IB,Crome P

更新日期：2018-03-01 00:00:00

abstract：:Inappropriate prescribing (IP) is a common and serious global healthcare problem in elderly people, leading to increased risk of adverse drug reactions (ADRs), polypharmacy being the main risk factor for both IP and ADRs. IP in older people is highly prevalent but preventable; hence screening tools for IP have been de...

journal_title：Age and ageing

authors： O'Mahony D,Gallagher PF

更新日期：2008-03-01 00:00:00

abstract：:Energy intake and resting energy expenditure in relation to body composition were studied in female patients with Alzheimer's disease, multi-infarct dementia and in home-living non-demented elderly women. Patients with Alzheimer's disease tended to have lower body weight and higher energy intake (p = NS) than control ...

journal_title：Age and ageing

authors： Niskanen L,Piirainen M,Koljonen M,Uusitupa M

更新日期：1993-03-01 00:00:00

abstract：OBJECTIVES:The objectives of this study were to (i) survey the risk factors for NSAID gastropathy in outpatients (elderly patients in the community), compared to those living in old people's homes or nursing homes, (ii) study the prescription of medication prophylaxis during use of NSAIDs conform the current national g...

journal_title：Age and ageing

authors： van Leen MW,van der Eijk I,Schols JM

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:high morale is defined as future-oriented optimism. Previous research suggests that a high morale independently predicts increased survival among old people, though very old people have not been specifically studied. OBJECTIVE:to investigate whether high morale is associated with increased survival among ve...

journal_title：Age and ageing

authors： Niklasson J,Hörnsten C,Conradsson M,Nyqvist F,Olofsson B,Lövheim H,Gustafson Y

更新日期：2015-07-01 00:00:00