Structural evolution of multisubunit RNA polymerases.

Abstract:

:Evolutionarily related multisubunit RNA polymerases (RNAPs) facilitate gene transcription throughout the three domains of life. During the past seven years an increasing number of bacterial and eukaryotic RNAP structures have been solved; however, the archaeal enzyme remained elusive. Two reports from the Murakami and Cramer laboratories have now filled this gap in our knowledge and enable us to hypothesize about the evolution of the structure and function of RNAPs.

journal_name

Trends Microbiol

journal_title

Trends in microbiology

authors

Werner F

doi

10.1016/j.tim.2008.03.008

subject

Has Abstract

pub_date

2008-06-01 00:00:00

pages

247-50

issue

6

eissn

0966-842X

issn

1878-4380

pii

S0966-842X(08)00106-6

journal_volume

16

pub_type

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