Cytokine profile of Armenian patients with Familial Mediterranean fever.

abstract：:Altered urinary excretion of glycosaminoglycans (GAG) has been reported in patients with nephrolithiasis, with chronic glomerulonephritis, and incipient diabetic nephropathy, but evaluation of urinary GAG has not been reported in infections and proliferating diseases of the urinary tract. Urinary excretion of GAG was ...

journal_title：Clinical biochemistry

authors： Baggio B,Gambaro G,Cicerello E,Mastrosimone S,Marzaro G,Borsatti A,Pagano F

更新日期：1987-12-01 00:00:00

abstract：BACKGROUND:Vitamin B12 insufficiency/deficiency is common in mixed patient populations. However there is no single marker which can reliably diagnose B12 insufficiency/deficiency. Elevated concentrations of methylmalonic acid (MMA) are considered the most representative marker of metabolic vitamin B12 insufficiency, bu...

journal_title：Clinical biochemistry

authors： Sobczyńska-Malefora A,Gorska R,Pelisser M,Ruwona P,Witchlow B,Harrington DJ

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Modern serum protein electrophoresis (SPE) resolves serum proteins in 6 major fractions, splitting beta (B) into beta1 (B1) and beta2 (B2). Beta-migrating monoclonal immunoglobulins (B-MC) commonly integrate into normal-looking peak shape(s) but may increase the fraction value, forming the basis for reflex t...

journal_title：Clinical biochemistry

authors： Chan PC,Lem-Ragosnig B,Chen J

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVE:This study was conducted to investigate the potential role of intravascular oxidative stress in inexplicable episodes of coronary artery spasm (CAS) during coronary angiography (CAG). DESIGN AND METHODS:Serial patients with stable angina scheduled for routine CAG were prospectively evaluated. Patients with c...

journal_title：Clinical biochemistry

authors： Leu HB,Lin WT,Lin CP,Wu TC,Lin SJ,Chen JW

更新日期：2009-05-01 00:00:00

abstract：:This study was performed to investigate the antioxidant mechanisms of polymorphonuclear leucocytes (PMN) in active stage of Behçet's Disease. PMN activities of myeloperoxidase (p < 0.02), superoxide dismutase (p < 0.001), catalase (p < 0.005), and glutathione peroxidase (p < 0.005) were significantly lower in the pati...

journal_title：Clinical biochemistry

authors： Doğan P,Tanrikulu G,Soyuer U,Köse K

更新日期：1994-10-01 00:00:00

abstract：OBJECTIVES:In future pig-to-man xenotransplantation it is important to master tools that identify potentially xenogenic alphagalactose (Galalpha) antigens in the doner tissue. DESIGN AND METHODS:We have measured the binding potentials of Galalpha detecting lectins and antibodies, including a naturally occurring subfra...

journal_title：Clinical biochemistry

authors： Kirkeby S,André S,Gabius HJ

更新日期：2004-01-01 00:00:00

abstract：:Erythrocyte morphology, kinematic viscosity, and membrane lipid composition have not been well documented in heterozygous hypobetalipoproteinemia (HBL). In our study of nine subjects with HBL from two kindreds, three presented with schistocytes (3-6%) while two of them also showed acanthocytosis (25-35%) on their peri...

journal_title：Clinical biochemistry

authors： Gheeraert P,De Buyzere M,Delanghe J,De Scheerder I,Bury J,Rosseneu M

更新日期：1988-12-01 00:00:00

abstract：:This review discusses the question: which steps are essential or need to be optimized so that maternal plasma RNA sequencing for pre-eclampsia and related syndromes will become as specific and sensitive as maternal plasma DNA sequencing for trisomy? ...

journal_title：Clinical biochemistry

authors： Oudejans CB

更新日期：2015-10-01 00:00:00

abstract：:Plasma levels of dehydroepiandrosterone sulfate, dehydroepiandrosterone and delta 5-androstenediol were measured in several women throughout pregnancy. The levels of both dehydroepiandrosterone and its sulfate decreased while those of delta 5-androstenediol did not. The levels of binding of the latter steroid to plasm...

journal_title：Clinical biochemistry

authors： Bird CE,Cook SJ,Dressel DE,Clark AF

更新日期：1980-06-01 00:00:00

abstract：BACKGROUND:Therapeutic drug monitoring (TDM) of the widely prescribed antidepressant fluoxetine (FLU) is recommended in certain situations, such as occurrence of toxicity, inadequate response or suspect of poor adherence. Dried blood spot (DBS) sampling is an increasingly studied alternative for TDM, particularly for o...

journal_title：Clinical biochemistry

authors： da Silva ACC,Raasch JR,Vargas TG,Peteffi GP,Hahn RZ,Antunes MV,Perassolo MS,Linden R

更新日期：2018-02-01 00:00:00

abstract：:A fluorescence polarization (FP) technique was applied to the assay of lysozyme activity in human urine. In this assay system, reaction between enzyme and fluorescein-labelled substrate produced a decrease in the fluorescein polarization (P) value. Enzyme activity and rate of decrease of P value exhibited a hyperbolic...

journal_title：Clinical biochemistry

authors： Miura H

更新日期：1985-02-01 00:00:00

abstract：:The recently developed fluorescent immunoassay (FIA) for measuring serum carbamazepine concentration is compared to the established enzyme-multiplied-immunoassay-technique (EMIT). The Accuracy, precision and simplicity of these methods are comparable. The sensitivity of FIA is approximately eight times greater than th...

journal_title：Clinical biochemistry

authors： Carl GF,Smith DB,Dunn LP

更新日期：1982-12-01 00:00:00

abstract：BACKGROUND:In several studies, it was shown that there was a marked decrease in serum levels of HDL-C during infection and inflammation in general. In particular, a decrease in the level of serum HDL-C was also shown in pneumonia. Correlations between inflammatory markers such as acute phase proteins, cytokines and ser...

journal_title：Clinical biochemistry

authors： Deniz O,Tozkoparan E,Yaman H,Cakir E,Gumus S,Ozcan O,Bozlar U,Bilgi C,Bilgic H,Ekiz K

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVE:To clarify the possibility that midband Lp in LDL fractions might act as an atherogenic lipoprotein in their interaction with macrophages. DESIGN AND METHODS:Low density lipoproteins (LDL) isolated by zonal ultracentrifugation from midband lipoprotein-positive serum in type lib hyperlipidemics were subjected...

journal_title：Clinical biochemistry

authors： Kawano M,Shinomiya M,Kanzaki T,Morisaki N,Shirai K,Saito Y,Yoshida S

更新日期：1996-06-01 00:00:00

abstract：OBJECTIVES:Pediatric serum samples collected from healthy children in the CALIPER (Canadian Laboratory Initiative in Pediatric Reference Interval) project are stored at -80 °C for various periods of time. This study aimed to determine the stability of chemistry, protein, and hormone analytes under these conditions. DE...

journal_title：Clinical biochemistry

authors： Brinc D,Chan MK,Venner AA,Pasic MD,Colantonio D,Kyriakopolou L,Adeli K

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVES:The change in DNA methylation patterns can be used to distinguish between normal and cancer cells. The aim of the present study was to examine the 5' CpG island methylation patterns of the cancer-testis antigen (CT antigen) gene family, MAGE-As, in hepatocellular carcinoma (HCC), and to develop the DNA demet...

journal_title：Clinical biochemistry

authors： Qiu G,Fang J,He Y

更新日期：2006-03-01 00:00:00

abstract：:The initial step in the action of thyrotropin (TSH) is its binding to the TSH receptor. TSH receptor antibodies are detected in up to 90% of patients with Graves' disease. Serial measurements of TSH receptor antibodies in patients with Graves' hyperthyroidism are helpful in predicting relapse. The TSH receptor was pur...

journal_title：Clinical biochemistry

authors： Harrison LC,Leedman PJ

更新日期：1990-02-01 00:00:00

abstract：OBJECTIVE:Saposin C (SAP-C) is an essential activator of glucosylceramide (GlcCer)-β-glucosidase (GCase), the enzyme deficient in Gaucher's disease. In this study, we investigated the effects of chemically synthesized SAP-Cs (synthetic SAP-Cs) on GCase. METHODS:Enzymatic assays and western blot analyses were carried o...

journal_title：Clinical biochemistry

authors： Yoneshige A,Muto M,Watanabe T,Hojo H,Matsuda J

更新日期：2015-11-01 00:00:00

abstract：:Improving long-term management, life-quality and outcome of transplant recipients continues to be a challenge. The impact of highly chemoattractant proteins as chemokines on transplant outcome is undeniable. These immunoactive molecules are critical in a wide variety of physiological and pathological processes, such a...

journal_title：Clinical biochemistry

authors： Crescioli C

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:The clinical laboratory is responsible for reporting accurate and expeditious results. However, the pre-analytical phase is directly related to the procedure of specimen collection and is mostly out of the direct control of the laboratory; further, most pre-analytical errors are related to human factors. The...

journal_title：Clinical biochemistry

authors： Lee NY

更新日期：2019-08-01 00:00:00

abstract：:Fourteen antirheumatoid drugs were tested for their effects on the in vitro hyaluronidase activity of normal human serum. Four drugs produced significant changes in enzyme activity. Different results were obtained with ovine testicular hyaluronidase when diluted with either saline or inactivated human serum. No increa...

journal_title：Clinical biochemistry

authors： Salkie ML,Hannah CL,McNeil EM

更新日期：1976-08-01 00:00:00

abstract：OBJECTIVES:Angiotensin converting enzyme (ACE), G-Protein couple receptor (G-Prot), endothelial nitric oxide synthase (ecNOS), Leptin -2548G/A and uncoupling protein (UCP2) are potent regulators of intra renal hemodynamics and may be the causative factors contributing to the deterioration of renal functions. In recent ...

journal_title：Clinical biochemistry

authors： Tripathi G,Sharma RK,Baburaj VP,Sankhwar SN,Jafar T,Agrawal S

更新日期：2008-05-01 00:00:00

abstract：:Devices constructed for potential use as invasive bioprobes incorporate a selective receiving site for molecular or ionic recognition, and a transducer which is capable of translating a perturbation of physical chemistry of the determinant-site reaction (interaction) into a usable signal. Four types are envisioned--im...

journal_title：Clinical biochemistry

authors： Thompson M,Vandenberg ET

更新日期：1986-10-01 00:00:00

abstract：OBJECTIVE:The immune-inflammatory system has been implicated in the pathogenesis of diabetic nephropathy; however, many of the mechanisms involved remain unclear. Chitotriosidase enzyme is an active human chitinase and a major protein product of activated macrophages. Although playing an important role in innate and ac...

journal_title：Clinical biochemistry

authors： Elmonem MA,Amin HS,El-Essawy RA,Mehaney DA,Nabil M,Kamel LN,Farid IM

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVES:Development of an ELISA for human insulin that utilizes monoclonal antibodies (mAbs) produced in serum-free medium. DESIGN AND METHODS:Insulin mAbs were produced in vitro by hybridomas in serum-free medium. A two-step ELISA was developed to replace bovine insulin (standard) and bovine serum albumin (assay b...

journal_title：Clinical biochemistry

authors： Even MS,Sandusky CB,Barnard ND,Mistry J,Sinha MK

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:To confirm that the naproxen metabolite O-desmethylnaproxen interferes with the Jendrassik and Grof method for total bilirubin and was a possible cause of spurious hyperbilirubinemia in a case of naproxen overdose. DESIGN AND METHODS:Plasma was spiked with naproxen or O-desmethylnaproxen before total and dir...

journal_title：Clinical biochemistry

authors： Al Riyami N,Zimmerman AC,Rosenberg FM,Holmes DT

更新日期：2009-01-01 00:00:00

abstract：:Two studies are described in this paper for the purpose of extending the application of the Dupont ACA glucose method to (1) analysis of specimens containing sodium fluoride and sodium iodoacetate, and (2) analysis of specimens containing EDTA, provided analysis is conducted immediately following specimen collection a...

journal_title：Clinical biochemistry

authors： Dubois JA,Roberts G,Beekman J

更新日期：1982-04-01 00:00:00

abstract：:The structure of enzyme active sites and the nature of the catalytic process are reviewed. The impressive efficiency of these protein catalysts appears to stem from such factors as proximity and orientation of enzyme and substrate moieties, strain, and the occurrence of distinctive microenvironments within catalytic c...

journal_title：Clinical biochemistry

authors： Blair AH

更新日期：1976-06-01 00:00:00

abstract：OBJECTIVES:Molecular screening plays a major role in prognostic categorization and subsequent definition of treatment strategies for acute myeloid leukemia. The possibility of using IDH1/2 mutations as a marker for the monitoring of minimal residual disease (MRD) is still under investigation and remains unclear. METHO...

journal_title：Clinical biochemistry

authors： Petrova L,Vrbacky F,Lanska M,Zavrelova A,Zak P,Hrochova K

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVES:We undertook the present study to investigate the possible relation between total antioxidant capacity (TAC) and tumor marker (TM) values in serum samples of patients with and without gastrointestinal tract and prostate tumors. DESIGN AND METHODS:We measured the TAC using trolox equivalent antioxidant capac...

journal_title：Clinical biochemistry

authors： López Vélez M,Martínez Martínez F

更新日期：2011-09-01 00:00:00