Abstract:
:S 872419 A, a specific receptor antagonist of peptide leukotrienes, was tested in the early-phase treatment of chemically burned eye (0.25 mol/l sodium hydroxide) of the rabbit. The drug was topically applied 5 times a day in a 1% solution, controls were the untreated opposite eye. Gross and microscopic investigations indicated that S 872419 A inhibits the inflammatory response of the chemically burned anterior eye segment. The parameters of healing considered (epithelial regeneration, corneal clouding and swelling, infiltration with polymorphonuclear leukocytes) suggest inhibition of lipoxygenase-mediated reactions in the tissue. PGF2 alpha levels were the same in aqueous humour of treated and untreated eyes. Further experiments with S 872419 A and other nonsteroidal drugs should improve the anti-inflammatory therapy of the chemically burned eye.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Struck HG,Geiser H,Block HU,Mest HJ,Tost Msubject
Has Abstractpub_date
1991-07-01 00:00:00pages
137-41issue
3eissn
1120-6721issn
1724-6016journal_volume
1pub_type
杂志文章abstract::Two cases of idiopathic sclerochoroidal calcification are reported with follow-up of two and ten years. In addition we have reviewed 102 cases of choroidal osteoma, including six misleading case reports which actually described idiopathic sclerochoroidal calcification and not choroidal osteoma. Clinical manifestation ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1991-10-01 00:00:00
abstract::Retinal ganglion cells (RGCs) undergo programmed cell death (apoptosis) after axonal injury. This cell death is mediated by several mechanisms, including deprivation of neurotrophic factors, alterations in gene expression, and production of reactive oxygen species. However, death of RGCs is delayed after axonal injury...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,评审
doi:
更新日期:1999-01-01 00:00:00
abstract::The primary aim of this study was to summarize and illustrate the main structural cross-sectional optical coherence tomography findings encountered after vitreoretinal surgery for rhegmatogenous retinal detachment. This was a non-systematic review of literature on structural cross-sectional optical coherence tomograph...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1177/1120672120911334
更新日期:2020-07-01 00:00:00
abstract:PURPOSE:To study the actual and standardized morbidity of malignant tumours with ocular location (per 100,000 inhabitants) over a period of ten years. METHODS:Retrospective evaluation of the registers of the Plovdiv District Oncology Centre and the Department of Ophthalmology in the Medical University. It includes 698...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1996-04-01 00:00:00
abstract:PURPOSE:The aim of this article is to describe a novel surgical technique for sutureless scleral fixation of an intraocular lens using the newly developed FIL SSF Carlevale IOL (Soleko, Italy). METHODS:Four eyes of four patients with poor capsular support were recruited to our study, three resulting from intraocular l...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120902020
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:To investigate the efficacy of intravitreal dexamethasone implants (DEX) after anti-VEGF failure in retinal vein occlusion macular oedema. METHODS:Retrospective cohort study of DEX implant (0.7 mg) given after anti-VEGF 'failure'. Switch to DEX occurred if a ⩽ +5 ETDRS letter gain and ⩽20% reduction in central...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120978355
更新日期:2020-12-27 00:00:00
abstract:PURPOSE:The convergence excess esotropia (CEET) is defined when near esotropia is greater than the distance by at least 10 PD while the eye is corrected with the full cycloplegic refraction. The purpose of this study is to evaluate the effect of a modified technique of Y- split recession of the medial rectus muscles on...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120965494
更新日期:2020-10-23 00:00:00
abstract:PURPOSE:The objective of the study was to compare the intraocular pressure (IOP)-lowering efficacy and safety of travoprost 0.004%/timolol 0.5% ophthalmic solution (Trav/Tim) to latanoprost 0.005%/timolol 0.5% ophthalmic solution (Lat/Tim), dosed once daily in the morning, in patients with open-angle glaucoma (OAG) or ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1177/112067210701700206
更新日期:2007-03-01 00:00:00
abstract:PURPOSE:To determine the incidence, timing and risk factors for glaucoma and visual axis opacification development following surgery for congenital cataract in the first year of life. METHODS:A prospective case series of all cataract surgery performed in Temple Street Children's University Hospital over a 28-year peri...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119862878
更新日期:2020-11-01 00:00:00
abstract:PURPOSE:To report management of diplopia with botulinum toxin injection in traumatic multiple ocular motor cranial neuropathies. METHODS:Alternate prism and cover measurement of deviation in different positions of gaze, examination of ductions, field of binocular single vision, and complete ocular anterior and poste...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000202
更新日期:2012-11-01 00:00:00
abstract:PURPOSE:To analyze the anatomic and functional consequences of wine-cork injury to the eye in relation to the patient's age and the type of cork and wine. METHODS:We retrospectively studied 13 patients, six women and seven men, presenting to our department with bottle-cork injury to the eye between January 1999 and Ju...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210301300308
更新日期:2003-04-01 00:00:00
abstract:PURPOSE:To describe the clinical features of a rare case of NBAS-SOPH-like mutations; to emphasize special aspects of the ocular and oro-facial regions. METHODS:Case report. CASE DESCRIPTION:We present a 5-year-old girl initially examined for her dysmorphic features, mental delay, strabismus, and high myopia. During ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119836335
更新日期:2020-03-01 00:00:00
abstract:PURPOSE:To determine the relationship between movements of the posterior and anterior eye segments during arbitrary gaze shifts and to obtain information for monitoring fixation during radiotherapy for ocular diseases. METHODS:We examined eye movements of ten emmetropic volunteers in a 1.5 T magnetic resonance system....
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210301300212
更新日期:2003-03-01 00:00:00
abstract:PURPOSE:Fabry disease retinal vascular involvement has been widely reported, with narrowing of the retinal arterioles, dilation and irregularity of the retinal veins, and exaggerated tortuosity of the retinal vessels. We evaluated retinal vessel diameter in Fabry disease, by means of a dedicated software, aiming to pro...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119886985
更新日期:2021-01-01 00:00:00
abstract:PURPOSE:The aim of this study is to compare the outcomes of micropulse transscleral cyclophotocoagulation between primary open-angle glaucoma, pseudoexfoliation glaucoma, and other types of secondary glaucoma. METHODS:Outcomes of 96 consecutive patients with refractory, end-stage glaucoma treated with micropulse trans...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120914231
更新日期:2020-03-31 00:00:00
abstract:PURPOSE:To present a new indicator that measures the sulci of the lacrimal lake of the eye according to the degrees of ocular abduction at which they vanish. This new approach will help determine the severity and progression of mucosal retraction in ocular surface diseases. METHODS:A total of 181 eyes of 94 healthy pe...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210101100303
更新日期:2001-07-01 00:00:00
abstract::Blood flow in various tissues of the body shows spontaneous variations. The purpose of this study was to analyze variations over time in the blood flow of the optic nerve head. Blood flow was measured by the laser Doppler flowmeter (LDF) in 12 healthy volunteers, and analyzed by spectral Fourier analysis. The LDF tech...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1997-10-01 00:00:00
abstract:PURPOSE:To analyze and compare the high performance liquid chromatography (HPLC) runs of tear proteins from diabetic (DIDRY) and non-diabetic (DRY) dry-eye patients, and healthy subjects (CTRL). The patterns were analyzed using multivariate statistical methods. METHODS:Tears (total 56 eyes: CTRL: n=16, DIDRY: n=21, an...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210101100105
更新日期:2001-01-01 00:00:00
abstract::Ocular injuries are a frequent cause of monocular blindness and cause disfigurement and discomfort. We developed a measure of severity for eye injuries using a multi-attribute utility (MAU) model. The severity index scoring was applied to eye injuries that presented at hospitals in Wisconsin, U.S.A. The resulting dist...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1993-04-01 00:00:00
abstract::The purpose of this study was to evaluate the hemodynamic changes occurring in the ophthalmic vasculature of eyes with Behçet's disease in a controlled clinical trial. Both eyes of patients with retinal involvement due to Behçet's disease were consecutively evaluated and were established as having mild or severe retin...
journal_title:European journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1997-07-01 00:00:00
abstract::Age-related macular degeneration is a condition (a) characterized by accumulation of membranous debris on both sides of the retinal pigment epithelium (RPE) basement membrane. Clinical manifestations of drusen, atrophy of the RPE/choriocapillaris, RPE detachment, and choroidal new vessel (CNV) formation occur after ag...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,评审
doi:
更新日期:1998-10-01 00:00:00
abstract:PURPOSE:To assess the safety and efficacy of hybrid vitreous surgery combining active 23-G ports with a sutured 20-G 6-mm infusion cannula for performing vitrectomy in endophthalmitis and trauma. METHODS:This is a retrospective analysis of 10 eyes with endophthalmitis and 10 eyes with trauma requiring vitreous surgery...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000988
更新日期:2018-01-01 00:00:00
abstract:PURPOSE:The purpose of this study was to assess indications and outcome of carotid Doppler ultrasound requested by ophthalmologists from an eye hospital over a period of three years. METHODS:This retrospective study was designed to analyse data for all patients referred to have carotid Doppler ultrasound from 1999 to ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:2004-05-01 00:00:00
abstract:PURPOSE:The purpose of this study is to test non-inferiority of a lower dose of crosslinked hyaluronic acid (CLHA) to a higher dose of carmellose eye drop in menopause patients receiving antidepressant treatments. METHODS:This prospective, double-blind, single-center study enrolled sixty female patients. Mean age was ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120972026
更新日期:2020-11-05 00:00:00
abstract::Rising healthcare costs and increasing demands for health care require techniques to choose between competing uses and even rationing of health care. Economic evaluations and health technology assessments are increasingly a means to assess the cost effectiveness of healthcare interventions so as to inform such resourc...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1177/1120672117747040
更新日期:2018-07-01 00:00:00
abstract:PURPOSE:To check whether three months' follow-up is sufficient to determine endothelial cell loss after cataract surgery and whether this value depends on preoperative central endothelial cell density. METHODS:A two-year prospective assessment of central endothelial cell density was done in 60 eyes after phacoemulsifi...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210201200106
更新日期:2002-01-01 00:00:00
abstract::This prospective study of 123 patients undergoing cataract extraction determined the preoperative and surgical factors predisposing to an exaggerated postoperative inflammatory response. It is important to identify the patients at increased risk of complications requiring additional prophylaxis or more intensive posto...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract:PURPOSE:To investigate the low mesopic contrast sensitivity function (LMCSF) of patients implanted with different modern optical bifocal and trifocal designs of multifocal intraocular lenses (mfIOLs). METHODS:This prospective, comparative, nonrandomized consecutive case series included 180 eyes that underwent cataract...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000777
更新日期:2016-11-04 00:00:00
abstract::Copper intraocular foreign bodies (IOFB) are relatively common after penetrating eye injuries. Ocular signs and symptoms vary greatly in relation to the copper content, ranging from chronic uveitis and severe visual loss for IOFB containing more than 85% copper, to local copper deposits with no severe ocular damage fo...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1995-10-01 00:00:00
abstract:PURPOSE:Cataract formation represents a serious problem in the elderly, and has a large impact on healthcare budget. The oxidative stress form and intensity might determine the cataract type and pigmentation, making efforts in the cataract prevention challenge more complex. METHODS:This is a retrospective cross-sectio...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210801800501
更新日期:2008-09-01 00:00:00