Cisplatin treatment of NIH/3T3 cultures induces a form of autophagic death in polyploid cells.

abstract：:Chronic lung allograft dysfunction (CLAD) still remains a major drawback in the outcome following lung transplantation (LTx). New therapeutic strategies are warranted. Growth factors and their receptors like platelet-derived growth factor-receptor (PDGFR) and vascular endothelial growth factor-receptor (VEGFR), may pl...

journal_title：Histology and histopathology

authors： Keil L,Schaub AL,Hirt SW,Schmid C,Lehle K,von Suesskind-Schwendi M

更新日期：2019-07-01 00:00:00

abstract：:Laminin (LAM) and fibronectin (FI) are regarded as major components of the glomerular extracellular matrix. The aim of this study was to define the distribution of LAM and FI in primary glomerulonephritis (GN) and GN of systemic lupus erythematosus (SLE) and to correlate the type of glomerular disorders with possible ...

journal_title：Histology and histopathology

authors： Nakapoulou I,Stefanaki K,Zeis PM,Papadakis J,Boletis J,Vosnidis G,Davaris P

更新日期：1993-07-01 00:00:00

abstract：:Calcium/calmodulin-dependent protein kinase II (CaMKII) is considered one of the key intracellular signaling proteins for development of neuropathy. We analyzed the expression of total CaMKII (tCaMKII) and its alpha, beta, gamma and delta isoforms in dorsal root ganglia (DRG) in a rat model of Diabetes mellitus type I...

journal_title：Histology and histopathology

authors： Ferhatovic L,Jelicic Kadic A,Boric M,Puljak L

更新日期：2014-05-01 00:00:00

abstract：:The authors present a case of benign oncocytoma (oxyphil cell adenoma) of the nasal cavity in a young woman. This is the fifth case reported in that region. Immunohistochemical stains revealed positivity only for cytokeratin. ...

journal_title：Histology and histopathology

authors： Miracco C,Sensini I,Vessio G,Luzi P

更新日期：1986-01-01 00:00:00

abstract：:This study evidences the presence of primordial germ cells, in tissue squash preparations and sections from hematological malignancies. Primordial germ cells were identified by their morphology, the intense PAS, PAS-D reaction and presence of calcium-activated neutral proteinase. Primordial germ cells gave rise to nuc...

journal_title：Histology and histopathology

authors： Logothetou-Rella H

更新日期：1996-10-01 00:00:00

abstract：:The present study investigated the chemical coding of mammary gland-projecting dorsal root ganglia (DRG) neurons using double-labelling immunohistochemistry. Earlier investigations revealed the presence of Fast blue - positive (FB+) neurons in Th9-Th12 DRG after injection of the tracer into the second, right thoracic ...

journal_title：Histology and histopathology

authors： Franke-Radowiecka A

更新日期：2011-12-01 00:00:00

abstract：:Systematic studies on hepatic stellate cells and myofibroblasts have so far mainly focused on cells located in the perisinusoidal space of Disse, the so-called littoral compartment. Here, these cells play a key role for intralobular fibrogenesis and sinusoidal capillarization. However, advanced hepatic fibrosis and ci...

journal_title：Histology and histopathology

authors： Zimmermann A,Zimmermann H,Fellay M,Reichen J

更新日期：1999-07-01 00:00:00

abstract：INTRODUCTION:Germline mutations in the tumour suppressor gene dyskeratosis congenit 1 (DKC1) cause the cancer prone syndrome called X-linked dyskeratosis congenita. The present study aims to determine whether mutations of the DKC1 gene may also be present in frequent human sporadic cancers (breast, colon and lung cance...

journal_title：Histology and histopathology

authors： Penzo M,Casoli L,Ceccarelli C,Treré D,Ludovini V,Crinò L,Montanaro L

更新日期：2013-03-01 00:00:00

abstract：:The transport mechanism of soluble molecules throughout the interstitial matrix is closely associated with human tumor behavior in vivo. However, the examination of soluble components in histological architectures has been hampered by artifacts caused during conventional tissue preparation. In this study, the immunodi...

journal_title：Histology and histopathology

authors： Bai Y,Ohno N,Terada N,Saitoh S,Nakazawa T,Nakamura N,Katoh R,Ohno S

更新日期：2009-06-01 00:00:00

abstract：:Immunohistochemistry of the terminal complement complex (C5b-9) and fibronectin (FN) is useful to detect myocardial ischemia preceding necrosis in the postmortem diagnosis of sudden cardiac death. The present immunohistochemical study examined connexin43 (Cx43) and zonula occludens-1 (ZO-1) as markers of early myocard...

journal_title：Histology and histopathology

authors： Kawamoto O,Michiue T,Ishikawa T,Maeda H

更新日期：2014-06-01 00:00:00

abstract：:The growth of a transplantable murine non-Hodgkin lymphoma tumour, developing either intraperitoneally as an ascites tumour or subcutaneously as a solid tumour, has been shown to be markedly diminished by including phytohaemagglutinin (PHA), a lectin present in raw kidney bean (Phaseolus vulgaris) in the diet. In NMRI...

journal_title：Histology and histopathology

authors： Pryme IF,Pusztai A,Bardocz S,Ewen SW

更新日期：1998-04-01 00:00:00

abstract：:The changes of implanted Harding-Passey melanoma in C57Bl/6J mice following treatment with wholebody hyperthermia were studied. The treated tumours showed a progressive growth delay, cellular and architectural irregularities as well as cell injury characteristics. The presence of distended and irregular blood vessels,...

journal_title：Histology and histopathology

authors： Vicente V,Gómez M,Gómez S,Calderon F,Canteras M,Cremades A

更新日期：1987-10-01 00:00:00

abstract：:Aurora A and Aurora B are serine-threonine kinase proteins which have both been implicated in human carcinogenesis through development of aneuploidy and chromosomal instability. The aim of the study is to assess the correlation of both markers with clinical and pathological parameters in patients with bladder cancer o...

journal_title：Histology and histopathology

authors： Bufo P,Sanguedolce F,Tortorella S,Cormio L,Carrieri G,Pannone G

更新日期：2010-11-01 00:00:00

abstract：:We examined morphological characteristics of the carotid body of spontaneously hypertensive rats (SHR), those of age-matched normotensive Wistar rats (NWR), and age-matched genetically comparable Wistar Kyoto rats (WKY). We examined the distribution and abundance of four different regulatory neuropeptides: substance P...

journal_title：Histology and histopathology

authors： Takahashi M,Matsuda H,Hayashida Y,Yamamoto Y,Tsukuda M,Kusakabe T

更新日期：2011-03-01 00:00:00

abstract：:A large number of biologically active substances have been identified and characterised in the respiratory tract of several mammals. These substances (amines and peptides) exert important regulatory influences on respiratory functions, and they act as neurotransmitters/neuromodulators, both being released from nerve t...

journal_title：Histology and histopathology

authors： Verástegui C,Fernández-Vivero J,Prada A,Rodríguez F,Romero A,González-Moreno M,de Castro JM

更新日期：1997-10-01 00:00:00

abstract：:The rapid Golgi method, combined with current optical and electronmicroscopical techniques, was used in three central gangliogliomas and in one dysplastic gangliocytoma of the cerebellum to study the morphology of ganglionic cells. Gangliogliomas were composed of bipolar, fusiform and radiate cells with dense core and...

journal_title：Histology and histopathology

authors： Ferrer I,Martí E,Guionnet N,Bella R,Serrano T,Towse J,Conesa G,Isamat F

更新日期：1990-07-01 00:00:00

abstract：:Platelet-derived growth factor-A (PDGF-A) is a locally produced growth factor in the rat testis secreted by both Sertoli cells and Leydig cells. It has been suggested that PDGF-A may be involved in modulation of testosterone production and may be essential to Leydig cell differentiation, however it is not known at wha...

journal_title：Histology and histopathology

authors： Fecteau KA,Mrkonjich L,Mason JI,Mendis-Handagama SM

更新日期：2006-12-01 00:00:00

abstract：:Infection with Helicobacter pylori (H. pylori) strains is linked to an increased risk of inflammation and gastric cancer. To investigate the effects of H. pylori on biological characteristics of gastric epithelial cells SGC-7901, derived from human adenocarcinoma, morphological appearances of both the pathogen and the...

journal_title：Histology and histopathology

authors： Wang P,Mei J,Tao J,Zhang N,Tian H,Fu GH

更新日期：2012-08-01 00:00:00

abstract：:In recent years, the different mechanisms of epithelial cell loss which occur in mammalian and avian small intestine have been re-investigated. Information is now available for a variety of mammalian types and mechanisms can be divided into two major classes: [i] those preserving epithelial integrity by maintaining in...

journal_title：Histology and histopathology

authors： Mayhew TM,Myklebust R,Whybrow A,Jenkins R

更新日期：1999-01-01 00:00:00

abstract：:We have studied the occurrence and specific features of liver cell dysplasia (LCD) in Chinese patients showing liver cirrhosis with or without hepatocellular carcinoma (HCC). Three types of LCD (SLCD, LLCDo, LLCDe) were morphologically defined, and these types were further analyzed using karyometry, estimation of nucl...

journal_title：Histology and histopathology

authors： Zhao M,Zhang NX,Du ZY,Laissue JA,Zimmermann A

更新日期：1994-01-01 00:00:00

abstract：:The coexistence of serotonin and cholecystokinin was studied in foetal sheep lungs at pseudoglandular stage of development by light microscopic immunohistochemistry. The coexistence was examined by staining consecutive sections with the different antibodies. Serotonin and cholecystokinin immunoreactivity was found wit...

journal_title：Histology and histopathology

authors： Balaguer L,Romano J,Ruiz-Pesini P

更新日期：1994-01-01 00:00:00

abstract：:Early observations that cultured mesenchymal stem cells (MSCs) could be induced to exhibit certain characteristics of osteocytes and chondrocytes led to the proposal that they could be transplanted for tissue repair through cellular differentiation. Therefore, many subsequent preclinical studies with transplanted MSCs...

journal_title：Histology and histopathology

authors： Lin CS,Xin ZC,Dai J,Lue TF

更新日期：2013-09-01 00:00:00

abstract：:Human epithelium contains keratin, which is expressed during differentiation. Depending on the target cell type, different types of keratin are expressed, and their alterations seem to represent changes in cell properties. The basal cells of oral epithelium express keratin 5 (K5), K14, K15 and K19, but their alteratio...

journal_title：Histology and histopathology

authors： Khanom R,Sakamoto K,Pal SK,Shimada Y,Morita K,Omura K,Miki Y,Yamaguchi A

更新日期：2012-07-01 00:00:00

abstract：:Vascular endothelial cells play a critical role in the maintenance of endometrial homeostasis. Indeed many pathological conditions causing abnormal endometrial bleeding including progestin only contraception, hormone replacement therapy, endometrial polyps, myomas, hyperplasia and cancer are associated with aberrant a...

journal_title：Histology and histopathology

authors： Krikun G,Mor G,Huang J,Schatz F,Lockwood CJ

更新日期：2005-07-01 00:00:00

abstract：:Various microscopic methods have been used to analyze the morphology and molecular distribution of cells and tissues. Using conventional procedures, however, ischemic or anoxic artifacts are inevitably caused by tissue-resection or perfusion-fixation. The in vivo cryotechnique (IVCT) was developed to overcome these pr...

journal_title：Histology and histopathology

authors： Ohno N,Terada N,Saitoh S,Zhou H,Fujii Y,Ohno S

更新日期：2007-11-01 00:00:00

abstract：:The nerve fiber distribution in the epidermis of the hairless rat skin was studied light microscopically by means of zinc iodide-osmium tetroxide staining. Two different morphological types of free nerve fiber endings could be detected: clusters of relatively thick nerve fibers stretched up through the spinous layer u...

journal_title：Histology and histopathology

authors： Müller T

更新日期：2000-04-01 00:00:00

abstract：:Peritumoral brain edema (PTBE) is considered to be one of the main biological behaviors of brain glioma. However, the histopathological features of PTBE remain imprecisely defined. We analyzed the histopathological characteristics in the PTBE area of 22 cases of glioma. Microscopically, the pre-existing basic structur...

journal_title：Histology and histopathology

authors： Wang X,Liu X,Chen Y,Lin G,Mei W,Chen J,Liu Y,Lin Z,Zhang S

更新日期：2015-09-01 00:00:00

abstract：:Neonatal hypoxic ischemia (HI) results in different extents of brain damage, and immature brain tissue is particularly sensitive to the stimulation of HI. Hypoxic-ischemic brain damage (HIBD) is a common and serious nervous system disease in neonates, for both full-term infants and preterm infants, and is one of the m...

journal_title：Histology and histopathology

authors： Yang L,Zhao H,Cui H

更新日期：2020-09-01 00:00:00

abstract：:A variety of studies have shown that incubation of different tumour cell lines with mistletoe lectins (MLs) in vitro has a marked cytotoxic effect. In the concentration range of low cytotoxicity cell death induced by ML-I is quantitatively due to apoptotic processes. The first events observed being membrane perforatio...

journal_title：Histology and histopathology

authors： Pryme IF,Bardocz S,Pusztai A,Ewen SW

更新日期：2006-03-01 00:00:00

abstract：:Neural stem cells are defined as clonogenic cells with self-renewal capacity and the ability to generate all neural lineages (multipotentiality). Cells with these characteristics have been isolated from the embryonic and adult central nervous system. Under specific conditions, these cells can differentiate into neuron...

journal_title：Histology and histopathology

authors： Bazán E,Alonso FJ,Redondo C,López-Toledano MA,Alfaro JM,Reimers D,Herranz AS,Paíno CL,Serrano AB,Cobacho N,Caso E,Lobo MV

更新日期：2004-10-01 00:00:00