Cognitive-behavioral therapy for adolescents with inflammatory bowel disease and subsyndromal depression.

Abstract:

OBJECTIVE:To examine the feasibility and efficacy of a manual-based cognitive-behavioral therapy (CBT) in reducing depressive symptomatology in adolescents with inflammatory bowel disease (IBD). Primary and Secondary Control Enhancement Therapy-Physical Illness (PASCET-PI) modified for youths with IBD was compared to treatment as usual (TAU), plus an information sheet about depression, without therapist contact using assessable patient analysis. METHOD:Following assessment, participants 11 to 17 years old with IBD and mild to moderate subsyndromal depression were randomly assigned to PASCET-PI (n = 22) or comparison treatment (n = 19). Primary outcome measures at baseline (T1) and 12 to 14 weeks posttreatment (T2) were Children's Depression Inventory (child/parent report), Schedule for Affective Disorders and Schizophrenia for School-Age Children (K-SADS), Children's Global Assessment Scale, and Perceived Control Scale for Children. RESULTS:The PASCET-PI group showed significantly greater improvement in Children's Depression Inventory (child/parent report), Children's Global Assessment Scale, and Perceived Control Scale for Children posttreatment than the comparison group. CONCLUSIONS:Screening and treatment of depressive symptoms in pediatric settings is feasible. PASCET-PI may be an efficacious intervention for subsyndromal depression in adolescents with IBD, although comparison with a more active treatment is necessary to attribute the improvement to PASCET-PI. CLINICAL TRIAL REGISTRATION INFORMATION:URL: http://clinicaltrials.gov. Unique identifier: NCT00446238.

authors

Szigethy E,Kenney E,Carpenter J,Hardy DM,Fairclough D,Bousvaros A,Keljo D,Weisz J,Beardslee WR,Noll R,DeMASO DR

doi

10.1097/chi.0b013e3180f6341f

subject

Has Abstract

pub_date

2007-10-01 00:00:00

pages

1290-1298

issue

10

eissn

0890-8567

issn

1527-5418

pii

S0890-8567(09)61847-5

journal_volume

46

pub_type

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