Emerging drugs for epilepsy and other treatment options.

Abstract:

:Epilepsies are amongst the most frequent chronic neurological conditions. Patients suffer from spontaneously recurring seizures because of sudden extensive electrical gray matter discharges. Although the current drug therapy allows many patients at least some degree of a satisfying course of the disease, a substantial number of patients remain without adequate seizure control. Reasons are either refractoriness to anticonvulsant drugs or intolerable drug-related side effects. Epilepsy surgery should be considered in these cases as possible treatment option. Nevertheless, a considerable rate of patients will not be suitable candidates or continue to have seizures despite surgery. Therefore there is a substantial need for better antiepileptic drugs. The aim of this review is to highlight currently emerging different treatment approaches which may ameliorate the perspectives of patients with difficult-to-treat epilepsies.

journal_name

Eur J Neurol

authors

Stefan H,Steinhoff BJ

doi

10.1111/j.1468-1331.2007.01706.x

subject

Has Abstract

pub_date

2007-10-01 00:00:00

pages

1154-61

issue

10

eissn

1351-5101

issn

1468-1331

pii

ENE1706

journal_volume

14

pub_type

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