Use of combination therapy in asthma: are they prescribed according to guidelines.

abstract：:The degree of risk of cross-infection of patients via lung function testing equipment has yet to be quantified. Based on current evidence, elaborate precautions are not justified for the majority of patients attending the laboratory, but attention to appropriate routine cleaning and disinfection protocols is important...

journal_title：Respiratory medicine

authors： Kendrick AH,Johns DP,Leeming JP

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Continuous, non-invasive assessment of alveolar ventilation achieved by transcutaneous PCO(2) (PtcCO(2)) monitoring is clearly superior to intermittent, invasive blood gas analyses in patients receiving nocturnal non-invasive positive pressure ventilation (NPPV), but the reliability and accuracy of PtcCO(2)-...

journal_title：Respiratory medicine

authors： Storre JH,Magnet FS,Dreher M,Windisch W

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Dysregulation of the prostaglandin E2 (PGE2) signaling pathway has been implicated in interstitial pneumonia (IP) pathogenesis. Due to the unstable nature of PGE2, available detection methods may not precisely reflect PGE2 levels. We explored the clinical usefulness of measuring stable prostaglandin E-major ...

journal_title：Respiratory medicine

authors： Horikiri T,Hara H,Saito N,Araya J,Takasaka N,Utsumi H,Yanagisawa H,Hashimoto M,Yoshii Y,Wakui H,Minagawa S,Ishikawa T,Shimizu K,Numata T,Arihiro S,Kaneko Y,Nakayama K,Matsuura T,Matsuura M,Fujiwara M,Okayasu I,I

更新日期：2017-01-01 00:00:00

abstract：PURPOSE:The Korea Centers for Disease Control & Prevention has implemented a review process for the approval of new drugs used to treat patients with multidrug-resistant tuberculosis (MDR-TB) since September 2016. Therefore, this study aimed to evaluate the efficacy and safety of these new drugs bedaquiline (Bdq) and d...

journal_title：Respiratory medicine

authors： Kang H,Jo KW,Jeon D,Yim JJ,Shim TS

更新日期：2020-06-01 00:00:00

abstract：:In this study healthy never-smoking subjects (n = 18) were recruited from a population study. Bronchoalveolar lavage (BAL), blood lymphocytes and bronchial biopsies, analysed both in the epithelium and lamina propria, were stained for T and B lymphocytes, natural killer (NK) cells and different subpopulations of T lym...

journal_title：Respiratory medicine

authors： Ekberg-Jansson A,Arvå E,Nilsson O,Löfdahl CG,Andersson B

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Despite the manifestations of primary ciliary dyskinesia (PCD) in early life, the diagnosis is often much delayed. Since 1998 in Cyprus, we have established the only national diagnostic and clinical referral center for PCD. OBJECTIVE:To review the phenotypic features at presentation of PCD patients in Cypru...

journal_title：Respiratory medicine

authors： Yiallouros PK,Kouis P,Middleton N,Nearchou M,Adamidi T,Georgiou A,Eleftheriou A,Ioannou P,Hadjisavvas A,Kyriacou K

更新日期：2015-03-01 00:00:00

abstract：PURPOSE:To investigate impact of distribution of computed tomography (CT) emphysema on severity of airflow limitation and gas exchange impairment in current and former heavy smokers participating in a lung cancer screening trial. MATERIALS AND METHODS:In total 875 current and former heavy smokers underwent baseline lo...

journal_title：Respiratory medicine

authors： Gietema HA,Zanen P,Schilham A,van Ginneken B,van Klaveren RJ,Prokop M,Lammers JW

更新日期：2010-01-01 00:00:00

abstract：:Maximal inspiratory (PImax) and expiratory (PEmax) mouth pressures were measured in seven normal adults in both sitting and half-lying positions on 2 days. Analysis of variance did not reveal significant differences between measurements made in the two positions for either PImax or PEmax. Measurements were repeatable ...

journal_title：Respiratory medicine

authors： Ng GY,Stokes MJ

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:Decreased lung function has health impacts beyond diagnosable lung disease. It is therefore important to understand the factors that may influence even small changes in lung function including obesity, physical fitness and physical activity. The aim of this study was to determine the anthropometric measure m...

journal_title：Respiratory medicine

authors： Rowe A,Hernandez P,Kuhle S,Kirkland S

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:Although high-resolution computed tomography (HRCT) is useful for the characterization of minute morphological changes in the lungs, no study has investigated risk factors for lung involvement detected by HRCT in patients with Sjögren's syndrome with or without respiratory symptoms. The aim of the current stu...

journal_title：Respiratory medicine

authors： Kakugawa T,Sakamoto N,Ishimoto H,Shimizu T,Nakamura H,Nawata A,Ito C,Sato S,Hanaka T,Oda K,Kido T,Miyamura T,Nakashima S,Aoki T,Nakamichi S,Obase Y,Saito K,Yatera K,Ishimatsu Y,Nakayama T,Korogi Y,Kawakami A,T

更新日期：2018-04-01 00:00:00

abstract：:The value of continuous positive airway pressure (CPAP) ventilation via a tight fitting face mask was assessed in eight HIV-1 antibody-positive patients with Pneumocystis carinii pneumonia who were in hypoxaemic respiratory failure. All patients were conscious, able to protect their airway and not hypercapnic. Treatme...

journal_title：Respiratory medicine

authors： Miller RF,Semple SJ

更新日期：1991-03-01 00:00:00

abstract：INRODUCTION:The mechanistic target of rapamycin inhibitors (mTORi) sirolimus and everolimus stabilize lung function in patients with pulmonary lymphangioleiomyomatosis (LAM) but do not induce remission. Pre-clinical studies suggest that simvastatin in combination with sirolimus induces LAM cell death. The objective of ...

journal_title：Respiratory medicine

authors： Krymskaya VP,Courtwright AM,Fleck V,Dorgan D,Kotloff R,McCormack FX,Kreider M

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Supplemental oxygen is a recommended therapy option in stable hypoxemic COPD patients. Often, supplemental oxygen is provided by continuous flow (CF). However, demand oxygen delivery systems (DODS) that provide an oxygen bolus only during inspiration have gained increasing use as they prolong oxygen cylinder...

journal_title：Respiratory medicine

authors： Gloeckl R,Jarosch I,Schneeberger T,Fiedler C,Lausen M,Weingaertner J,Hitzl W,Kenn K,Koczulla AR

更新日期：2019-09-01 00:00:00

abstract：:Heart-lung transplantation involves denervation of the lungs below the tracheal anastomosis, with associated permanent loss of all pulmonary innervation except post-ganglionic efferent nerves. This is supported by loss of the cough reflex to inhaled USNDW, which also implies that the RARs which mediate this cough mech...

journal_title：Respiratory medicine

authors： Hathaway T,Higenbottam T,Lowry R,Wallwork J

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:The presence of non-reversible airway obstruction (AO) in never smokers has only received limited attention until now. METHODS:We analyzed data from the Austrian Burden of Obstructive Lung Disease (BOLD) study. We defined non-reversible AO as post-bronchodilator FEV(1)/FVC <0.7 which corresponds to COPD I a...

journal_title：Respiratory medicine

authors： Lamprecht B,Schirnhofer L,Kaiser B,Buist S,Studnicka M

更新日期：2008-12-01 00:00:00

abstract：:Subjects with chronic obstructive airways disease may have difficulty with the roadside alcolmeter. Twenty-six subjects with a FEV1/FVC less than 60% were asked to use an alcolmeter simulator. Only ten were able to produce the necessary flow rate of 28 l min-1 for a minimum of 2.7 s, two could produce the same total v...

journal_title：Respiratory medicine

authors： Briggs JE,Patel H,Butterfield K,Honeybourne D

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVES:To assess the utility of capsaicin test in the differential diagnosis of non-productive causes of chronic cough and to examine the effects of treatment on this reflex. PARTICIPANTS:86 healthy volunteers and 101 patients with chronic cough: asthma (n: 54) gastroesophageal reflux (n: 35) and post-nasal drip s...

journal_title：Respiratory medicine

authors： Nieto L,de Diego A,Perpiñá M,Compte L,Garrigues V,Martínez E,Ponce J

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:Patients with upper and lower airway symptoms and with pronounced sensitivity to chemical odours, such as perfumes, flower scents and tobacco smoke, have been suggested to have sensory hyperreactivity (SHR). The symptoms have been difficult to identify with physiological measurements and the effects of vario...

journal_title：Respiratory medicine

authors： Johansson A,Löwhagen O,Millqvist E,Bende M

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Exercise induced asthma may symptomatically be difficult to differentiate from exercise related obstruction in the upper airways, sometimes leading to diagnostic confusion and inappropriate treatment. Larynx accounts for a significant fraction of total airway resistance, but its role as a limiting factor for...

journal_title：Respiratory medicine

authors： Røksund OD,Maat RC,Heimdal JH,Olofsson J,Skadberg BT,Halvorsen T

更新日期：2009-12-01 00:00:00

abstract：:Totally implantable venous intravenous access devices (TIVADs) have an essential role in the frequent delivery of antibiotics in cystic fibrosis (CF) patients. This study at the Royal Brompton Hospital (RBH) reports the experience of TIVADs in patients attending the RBH adult CF unit implanted at the RBH and elsewhere...

journal_title：Respiratory medicine

authors： Kariyawasam HH,Pepper JR,Hodson ME,Geddes DM

更新日期：2000-12-01 00:00:00

abstract：:Chemokines such as regulated on activation, normal T-cell expressed and secreted (RANTES), monocyte chemoattractant protein (MCP)-1, monocyte inflammatory protein (MIP)-lalpha have been reported to play an important role in the pathogenesis of interstitial lung diseases. Among idiopathic interstitial pneumonia (IIP), ...

journal_title：Respiratory medicine

authors： Yoshioka S,Mukae H,Sugiyama K,Kakugawa T,Sakamoto N,Nakayama S,Abe K,Fujii T,Kadota J,Kohno S

更新日期：2004-10-01 00:00:00

abstract：:Beclometasone dipropionate (BDP) extrafine is a hydrofluoroalkane-based, chlorofluorocarbon (CFC)-free inhalation aerosol. This study was conducted to determine whether BDP extrafine and CFC-fluticasone proprionate (FP) aerosols were equivalent in terms of efficacy and tolerability in children with symptomatic mild-to...

journal_title：Respiratory medicine

authors： van Aalderen WM,Price D,De Baets FM,Price J

更新日期：2007-07-01 00:00:00

abstract：INTRODUCTION:In vivo, the airway epithelium stretches and relaxes with each respiratory cycle, but little is known about the effect this pattern of elongation and relaxation has on bronchial epithelial cells. We have used a model of cell deformation to measure the effect of stretch on inflammatory cytokine release by t...

journal_title：Respiratory medicine

authors： Thomas RA,Norman JC,Huynh TT,Williams B,Bolton SJ,Wardlaw AJ

更新日期：2006-09-01 00:00:00

abstract：:Samples of lung tissue, taken at time of lung transplant, from 13 Dutch Caucasian patients with idiopathic pulmonary arterial hypertension (iPAH) and 14 patients with non-idiopathic PAH were studied for the presence of human herpes virus-8 (HHV-8). By immunohistochemical staining, in none of patients expression of HHV...

journal_title：Respiratory medicine

authors： Bresser P,Cornelissen MI,van der Bij W,van Noesel CJ,Timens W

更新日期：2007-04-01 00:00:00

abstract：:In a double-blind study of 60 patients undergoing fibreoptic bronchoscopy we have compared the local anaesthetic effects of intratracheal injections of cocaine (4 ml, 2.5%) and lignocaine (4 ml, 4%). The two local anaesthetics were equally effective in terms of cough suppression, requirement for extra local anaestheti...

journal_title：Respiratory medicine

authors： Teale C,Gomes PJ,Muers MF,Pearson SB

更新日期：1990-09-01 00:00:00

abstract：:Report of an incidental chest X-ray finding of a large vessel dilation at the root of the ascending aorta in a 65-year-old female patient while pre-operative routine diagnostic. Due to prior allergic reaction to iodine contrast agent, non-invasive imaging was performed with magnetic resonance imaging (MRI), where the ...

journal_title：Respiratory medicine

authors： Ritter CO,Weininger M,Machann M,Beissert M,Hahn D,Kenn W

更新日期：2008-05-01 00:00:00

abstract：:Ankylosing spondylitis (AS) is a chronic seronegative spondyloarthritis with the major histocompatibility antigen HLA B27. Pulmonary involvement in AS is rare and is usually in the form of upper lobe fibrocavitary disease. Herein, we present a case with recurrent pleural and pericardial effusion without apical fibrobu...

journal_title：Respiratory medicine

authors： Erkan L,Uzun O,Findik S,Atici AG,Ozkaya S

更新日期：2007-02-01 00:00:00

abstract：:Assessment of asthma severity is important for disease management. Analysis of symptoms past and present, and previous and actual lung function measurements (including variability) is the usual method of evaluation and classification of asthma disease severity and activity. However, symptoms and lung function alterati...

journal_title：Respiratory medicine

authors： Dahl R,Martinati LC,Boner AL

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND:The synergistic interactions between pharmacotherapy and pulmonary rehabilitation has been provided, but it remains to be established whether this may also apply to more severe patients. OBJECTIVES:We have examined whether tiotropium enhances the effects of exercise training in patients with advanced COPD (...

journal_title：Respiratory medicine

authors： Pasqua F,Biscione G,Crigna G,Auciello L,Cazzola M

更新日期：2010-03-01 00:00:00

abstract：:In the drive to replace chlorofluorinated hydrocarbons (CFCs) by alternative more environmentally friendly propellants in pressurized metered dose inhalers (pMDIs), Chiesi has developed new inhalers using Modulite technology. The aim was to obtain CFC-free pMDIs which are equivalent, in terms of safety and efficacy, t...

journal_title：Respiratory medicine

authors： Woodcock A,Acerbi D,Poli G

更新日期：2002-08-01 00:00:00