Maximal inspiratory and expiratory mouth pressures in sitting and half-lying positions in normal subjects.

abstract：BACKGROUND:A predominant feature of asthma is an accelerated rate of decline in forced expiratory volume in 1 s (FEV1), but data on the variability and factors associated with this change in patients with controlled asthma are largely unknown. METHODS:140 patients with controlled asthma were enrolled based on the Glob...

journal_title：Respiratory medicine

authors： Matsunaga K,Ichikawa T,Oka A,Morishita Y,Kanai K,Hiramatsu M,Akamatsu H,Kawabata H,Kikuchi T,Akamatsu K,Hirano T,Kou Y,Nakanishi M,Minakata Y,Yamamoto N

更新日期：2014-07-01 00:00:00

abstract：:We report the first study of triple-dose immunotherapy with heat-killed Mycobacterium vaccae (SRL 172) combined with short-course, directly observed chemotherapy in newly diagnosed pulmonary tuberculosis patients. The study was carried out in Rosario, Argentina, where single-dose immunotherapy with M. vaccae has previ...

journal_title：Respiratory medicine

authors： Dlugovitzky D,Fiorenza G,Farroni M,Bogue C,Stanford C,Stanford J

更新日期：2006-06-01 00:00:00

abstract：STUDY OBJECTIVES:To determine the medications prescribed to patients with chronic obstructive pulmonary disease (COPD) and their relationship to health-related quality of life (HRQL). METHODS:Cross-sectional study of 611 consecutive patients with stable, mild-to-severe COPD who attended at the respiratory service of a...

journal_title：Respiratory medicine

authors： Esteban C,Moraza J,Quintana JM,Aburto M,Capelastegui A

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Combination therapy with inhaled corticosteroids (ICS) and long-acting β(2)-adrenergic agonists (LABA) is reported to have superior effects on controlling asthma symptoms to ICS alone; however, there is no molecular-based evidence to explain the clinical effects. Here, the effect of the ICS/LABA combination ...

journal_title：Respiratory medicine

authors： Essilfie-Quaye S,Ito K,Ito M,Kharitonov SA,Barnes PJ

更新日期：2011-12-01 00:00:00

abstract：:Fifty patients with tropical eosinophilia were studied clinically and physiologically, before and after a standard 3-week course of diethylcarbamazine. Before treatment the main physiological abnormality was a reduction in the carbon monoxide transfer factor. One month after the start of treatment most patients had sh...

journal_title：Respiratory medicine

authors： Vijayan VK,Rao KV,Sankaran K,Venkatesan P,Prabhakar R

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:The aim of the study was to investigate the efficacy and safety of ciclesonide compared with budesonide in adolescents with severe asthma. METHODS:In this randomized, double-blind, double-dummy, parallel-group study, patients aged 12-17 years with severe asthma were treated with budesonide 400 microg once d...

journal_title：Respiratory medicine

authors： Vermeulen JH,Gyurkovits K,Rauer H,Engelstätter R

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:To determine the characteristics of persons with cognitive impairment being able to self-manage in chronic obstructive pulmonary disease (COPD). METHODS:In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidance this systematic review examined all studies in E...

journal_title：Respiratory medicine

authors： Baird C,Lovell J,Johnson M,Shiell K,Ibrahim JE

更新日期：2017-08-01 00:00:00

abstract：STUDY OBJECTIVES:The process of intermittent hypoxia-reoxygenation produces airway inflammation and endothelial dysfunction that favors the development of cardiovascular disorders in obstructive sleep apnea syndrome (OSAS). Nitric oxide (NO) is an important mediator in airway inflammation and the regulation of endothel...

journal_title：Respiratory medicine

authors： Fortuna AM,Miralda R,Calaf N,González M,Casan P,Mayos M

更新日期：2011-04-01 00:00:00

abstract：:Intrapulmonary percussive ventilation (IPV) is a ventilatory technique that delivers bursts of high-flow respiratory gas into the lung at high rates, intended for treating acute respiratory failure and for mobilization of secretions. We performed a study, aimed at assessing the physiological response to IPV, on patien...

journal_title：Respiratory medicine

authors： Nava S,Barbarito N,Piaggi G,De Mattia E,Cirio S

更新日期：2006-09-01 00:00:00

abstract：:Chemokines such as regulated on activation, normal T-cell expressed and secreted (RANTES), monocyte chemoattractant protein (MCP)-1, monocyte inflammatory protein (MIP)-lalpha have been reported to play an important role in the pathogenesis of interstitial lung diseases. Among idiopathic interstitial pneumonia (IIP), ...

journal_title：Respiratory medicine

authors： Yoshioka S,Mukae H,Sugiyama K,Kakugawa T,Sakamoto N,Nakayama S,Abe K,Fujii T,Kadota J,Kohno S

更新日期：2004-10-01 00:00:00

abstract：INTRODUCTION:Brit-Hogg-Dubé syndrome (BHD) is a rare disorder that is estimated to affects about 600 families in the World. The disease-causing mutations is on FLCN gene which codes for folliculin. This protein has a role in different organs as skin, kidney and lung, thanks to the interaction with type I and II cadheri...

journal_title：Respiratory medicine

authors： Marziali V,Geropoulos G,Frasca L,Longo F,Patrini D,Panagiotopoulos N,Crucitti P

更新日期：2020-07-01 00:00:00

abstract：:Rheumatoid arthritis (RA)-associated constrictive bronchiolitis is a severe condition with no established efficient treatment. A 55-year-old woman with seropositive RA developed rapidly progressive constrictive bronchiolitis confirmed by lung biopsy. Her clinical condition worsened despite steroids and azathioprine. T...

journal_title：Respiratory medicine

authors： Cortot AB,Cottin V,Miossec P,Fauchon E,Thivolet-Béjui F,Cordier JF

更新日期：2005-04-01 00:00:00

abstract：:The rapid increase in the elderly population is leading to a corresponding increase in the number of people requiring medical care. To date no comparative study between community-acquired pneumonia (CAP) and nursing home-acquired pneumonia (NHAP) has been reported in the very elderly non-intubated patients. The presen...

journal_title：Respiratory medicine

authors： Maruyama T,Gabazza EC,Morser J,Takagi T,D'Alessandro-Gabazza C,Hirohata S,Nakayama S,Ramirez AY,Fujiwara A,Naito M,Nishikubo K,Yuda H,Yoshida M,Takei Y,Taguchi O

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Having a child with a chronic disease may cause anxiety and depression and impair the sleep quality in the mothers. The aim of this study was to evaluate sleep quality in asthmatic children and their mothers as well as the status of anxiety-depression in the mothers. METHODS:Study group consisted of 75 asth...

journal_title：Respiratory medicine

authors： Yuksel H,Sogut A,Yilmaz O,Demet M,Ergin D,Kirmaz C

更新日期：2007-12-01 00:00:00

abstract：:Although pleural manometry is a relatively simple medical procedure it is only occasionally used to follow pleural pressure (Ppl) changes during a therapeutic thoracentesis and pneumothorax drainage. As some studies showed that pleural pressure monitoring might be associated with significant advantages, pleural manome...

journal_title：Respiratory medicine

authors： Grabczak EM,Krenke R,Zielinska-Krawczyk M,Light RW

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:This study evaluated the dose-response and dosing interval of the novel long-acting muscarinic receptor antagonist (LAMA) GSK573719 in patients with COPD. METHODS:This randomized, double-blind, placebo-controlled, 3-way cross-over, incomplete block study evaluated 5 once-daily doses of GSK573719 (62.5-1000 ...

journal_title：Respiratory medicine

authors： Donohue JF,Anzueto A,Brooks J,Mehta R,Kalberg C,Crater G

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Non-invasive ventilation (NIV) is increasingly used in the treatment of patients with chronic hypercapnic respiratory failure (CRF). Residual sleep related respiratory events under NIV such as obstructive or central apnea/hypopnea (AH), or patient-ventilator asynchrony (PVA), may compromise treatment efficac...

journal_title：Respiratory medicine

authors： Aarrestad S,Qvarfort M,Kleiven AL,Tollefsen E,Skjønsberg OH,Janssens JP

更新日期：2017-11-01 00:00:00

abstract：:Long-acting bronchodilators in combination with inhaled corticosteroids (ICS) are recommended to decrease the risk of recurrent exacerbations in patients with Global initiative for chronic Obstructive Lung Disease (GOLD) stage 3-4 chronic obstructive pulmonary disease (COPD). There is increasing concern about the clin...

journal_title：Respiratory medicine

authors： Magnussen H,Watz H,Kirsten A,Decramer M,Dahl R,Calverley PM,Towse L,Finnigan H,Tetzlaff K,Disse B

更新日期：2014-04-01 00:00:00

abstract：:Systemic inflammation may be present in patients with chronic obstructive pulmonary disease (COPD). Exercise is known to elicit an inflammatory response. We hypothesized that the systemic inflammatory response to exercise might be exaggerated in COPD patients compared to healthy subjects. Sixteen COPD patients and 11 ...

journal_title：Respiratory medicine

authors： van Helvoort HA,van de Pol MH,Heijdra YF,Dekhuijzen PN

更新日期：2005-12-01 00:00:00

abstract：:Smoking and body mass index (BMI) are well-documented risk factors that contribute substantially to chronic obstructive pulmonary disease (COPD) and asthma. However, the relations among smoking, obesity, and COPD or asthma remain to be clarified. We conducted a population-based cross-sectional epidemiologic study to e...

journal_title：Respiratory medicine

authors： Cazzola M,Calzetta L,Lauro D,Bettoncelli G,Cricelli C,Di Daniele N,Rogliani P

更新日期：2013-09-01 00:00:00

abstract：:Both albuterol and nedocromil sodium have been recognized to possess certain anti-inflammatory properties. However, there are no data on the impact of these drugs on the pathophysiology of the bronchial extracellular matrix in asthma characterized by enhanced tenascin (Tn) expression, known to occur proportional to th...

journal_title：Respiratory medicine

authors： Altraja A,Laitinen A,Meriste S,Marran S,Märtson T,Sillastu H,Laitinen LA

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Although massive bleeding following transbronchial lung biopsies (TBLB) is rare, even minor hemorrhage may prolong the procedure and result in inadequate sampling. Tranexamic acid (TXA) is an antifibrinolytic agent, which reduces bleeding in numerous scenarios, however, its prophylactic use in mitigating pos...

journal_title：Respiratory medicine

authors： Kuint R,Levy L,Cohen Goichman P,Huszti E,Abu Rmeileh A,Shriki O,Abutbul A,Fridlender ZG,Berkman N

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Computed tomography (CT) has been used for non-invasive quantitative assessment of airway dimensions, potentially showing airway remodeling, in asthma. However, most studies have examined either only one airway or only airways in anatomically unidentified cross-sections. Using software capable of precisely i...

journal_title：Respiratory medicine

authors： Shimizu K,Hasegawa M,Makita H,Nasuhara Y,Konno S,Nishimura M

更新日期：2010-12-01 00:00:00

abstract：:Synovial sarcoma most commonly occurs in the peri-articular regions of the extremities. The present report describes a rare case of primary biphasic synovial sarcoma of the pleura in an 18-year-old female. The diagnosis was made on the basis of light microscopy, immunohistochemistry, electron microscopy and the charac...

journal_title：Respiratory medicine

authors： Jawahar DA,Vuletin JC,Gorecki P,Persechino F,Macera M,Magazeh P

更新日期：1997-10-01 00:00:00

abstract：STUDY OBJECTIVES:To test if morbid obesity causes pulmonary function changes and if massive weight loss have effect on pulmonary function (especially in subjects with BMI>or=60 kg/m(2)). PARTICIPANTS:Thirty-nine morbid obese subjects before and after massive weight loss. MEASUREMENTS AND RESULTS:Patients had baseline...

journal_title：Respiratory medicine

authors： Santana AN,Souza R,Martins AP,Macedo F,Rascovski A,Salge JM

更新日期：2006-06-01 00:00:00

abstract：AIM:Recent studies have shown that anti-Ro52 antibody is associated with both interstitial lung disease (ILD) and the degree of disease severity in juvenile patients with dermatomyositis (DM). We found that more than half of adult patients with DM were positive for anti-Ro52 antibody. In this study, we analysed the cor...

journal_title：Respiratory medicine

authors： Xing X,Li A,Li C

更新日期：2020-10-01 00:00:00

abstract：:Cyclosporin A (CsA) is an immunomodulator drug that has been used in the treatment of several types of advanced pulmonary interstitial disease. This beneficial effect occurs mainly in circumstances in which alveolitis due to CD4 lymphocytes is absent, suggesting that CsA acts on other types of cells. The present study...

journal_title：Respiratory medicine

authors： Losa García JE,Mateos Rodríguez F,Jiménez López A,García Salgado MJ,Martín de Cabo MR,Pérez Losada J,Pérez Arellano JL

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVE:To assess whether tumor necrosis factor (TNF) antagonism can attenuate eosinophilic airway inflammation in patients with mild-to-moderate allergic asthma. DESIGN:Randomized, double-blind, placebo-controlled trial. SETTING:National Institutes of Health (NIH) Clinical Center. PATIENTS:Twenty-six patients wit...

journal_title：Respiratory medicine

authors： Rouhani FN,Meitin CA,Kaler M,Miskinis-Hilligoss D,Stylianou M,Levine SJ

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Although the prevalence of chronic obstructive pulmonary disease (COPD) increases with age, no specific therapeutic approaches are available till date for the elderly population. AIM:To assess the efficacy and safety of once-daily indacaterol 150 and 300 μg in elderly patients with moderate to severe COPD. ...

journal_title：Respiratory medicine

authors： Girodet PO,Jasnot JY,Le Gros V,Decuypère L,Cao W,Devouassoux G

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Apoptosis is thought to play an important role in the development of acute respiratory distress syndrome (ARDS). We evaluated the bronchoalveolar lavage (BAL) fluid from ARDS patients focusing on apoptosis. METHODS:The study enrolled 31 ARDS patients and 20 healthy controls. BAL fluid levels of caspase-clea...

journal_title：Respiratory medicine

authors： Lee KS,Choi YH,Kim YS,Baik SH,Oh YJ,Sheen SS,Park JH,Hwang SC,Park KJ

更新日期：2008-03-01 00:00:00