Issues surrounding standardization of meningococcal group W135 serology.

abstract：:The 146S particle of the foot and mouth disease virus which is used as a vaccine antigen was found to be relatively stable when stored for prolonged periods at 4 degrees C. However, stored antigens of virus strains of the SAT serotypes but not of a virus strain of the type O serotype became less thermostable at 37 deg...

journal_title：Vaccine

authors： Anderson EC,Doughty WJ,Muthiani A

更新日期：1983-12-01 00:00:00

abstract：:The costs of developing and producing new-generation vaccines have increased compared to many of the older, "traditional" vaccines because of new technologies and regulatory requirements. While the public sector often supports basic research costs, private manufacturers are usually responsible for the investments in p...

journal_title：Vaccine

authors： Batson A,Meheus F,Brooke S

更新日期：2006-08-31 00:00:00

abstract：BACKGROUND:Estimation of the magnitude of the herd effect on invasive pneumococcal disease (IPD) is important when evaluating health benefits and cost-effectiveness of paediatric pneumococcal conjugate vaccine (PCV) programmes and may influence policy makers' decisions on PCV use. Several epidemiological, programmatic,...

journal_title：Vaccine

authors： Pirçon JY,Talarico CA,Bollaerts K,Hausdorff WP,Clarke CJ

更新日期：2018-11-12 00:00:00

abstract：:It has been shown recently that BCG can be used as a live recombinant vaccine to stimulate immune responses. Proliferative or cytotoxic T-cell responses against several viral proteins such as HIV Gag, Env or Nef were obtained after parenteral immunization with BCG expressing these proteins. Antibody responses were als...

journal_title：Vaccine

authors： Lagranderie M,Murray A,Gicquel B,Leclerc C,Gheorghiu M

更新日期：1993-10-01 00:00:00

abstract：:Clostridium difficile is the leading cause of hospital-acquired diarrhea, also known as C. difficile associated diarrhea. The two major toxins, toxin A and toxin B are produced by most C. difficile bacteria, but some strains, such as BI/NAP1/027 isolates, produce a third toxin called binary toxin. The precise biologic...

journal_title：Vaccine

authors： Wang S,Rustandi RR,Lancaster C,Hong LG,Thiriot DS,Xie J,Secore S,Kristopeit A,Wang SC,Heinrichs JH

更新日期：2016-03-04 00:00:00

abstract：:Respiratory syncytial virus (RSV) causes severe respiratory illness in infants. There are no licensed vaccines to prevent RSV infection. The neonate receives short-term protection from maternally derived antibodies, which, however, can also interfere with the active response to vaccination. A RSV vaccine consisting of...

journal_title：Vaccine

authors： Garg R,Latimer L,Gerdts V,Potter A,van Drunen Littel-van den Hurk S

更新日期：2015-03-10 00:00:00

abstract：:The safety and immunogenicity of a new formulation of the inactivated hepatitis A vaccine, Avaxim, was evaluated in 189 children, aged 18 months to 15 years in a monocentric, open trial. Two vaccinations were given six months apart. Enrollment was balanced within three age groups: 18 months to 3 years, 4-8 years and 9...

journal_title：Vaccine

authors： Dagan R,Greenberg D,Goldenbertg-Gehtman P,Vidor E,Briantais P,Pinsk V,Athias O,Dumas R

更新日期：1999-04-09 00:00:00

abstract：:The purpose of this study was to investigate the utility of various in vitro and in vivo methods to assess the stability of experimental vaccines containing tetanus toxoid (TT) within PLGA microspheres. In vitro, the breakdown of the encapsulating polymers into their acid components led to changes in the structure of ...

journal_title：Vaccine

authors： Sasiak AB,Bolgiano B,Crane DT,Hockley DJ,Corbel MJ,Sesardic D

更新日期：2000-11-22 00:00:00

abstract：:The ability of monophosphoryl lipid A (MPL), QS-21 and alum to alter the immunologic response to immunization with respiratory syncytial virus a chimeric FG construct (FG) subunit vaccine was examined in BALB/c mice. FG/MPL, FG/alum, and FG/MPL/QS-21 combinations increased non-neutralizing antibody response, while FG/...

journal_title：Vaccine

authors： Neuzil KM,Johnson JE,Tang YW,Prieels JP,Slaoui M,Gar N,Graham BS

更新日期：1997-04-01 00:00:00

abstract：INTRODUCTION:Live-attenuated influenza vaccines (LAIVs) have the potential to be affordable, effective, and logistically feasible for immunization of children in low-resource settings. MATERIAL AND METHODS:We conducted a phase II, randomized, double-blind, parallel group, placebo-controlled trial on the safety of the ...

journal_title：Vaccine

authors： Ortiz JR,Goswami D,Lewis KD,Sharmeen AT,Ahmed M,Rahman M,Rahman MZ,Feser J,Neuzil KM,Brooks WA

更新日期：2015-06-26 00:00:00

abstract：:Clostridium difficile infection (CDI) causes nosocomial antibiotic-associated diarrhea and colitis in the developed world. Two potent cytotoxins, toxin A (TcdA) and toxin B (TcdB) are the virulence factors of this disease and can be a good vaccine candidate against CDI. In the present study, we genetically engineered ...

journal_title：Vaccine

authors： Guo S,Yan W,McDonough SP,Lin N,Wu KJ,He H,Xiang H,Yang M,Moreira MA,Chang YF

更新日期：2015-03-24 00:00:00

abstract：:Safety and efficacy of adjuvanted vaccines in autoimmune individuals raises growing clinical and scientific interest. Protection from influenza would bring particular benefits in these patients with common cardiac and respiratory impairment. This study evaluates efficacy, clinical safety and immune effects of the admi...

journal_title：Vaccine

authors： Setti M,Fenoglio D,Ansaldi F,Filaci G,Bacilieri S,Sticchi L,Ferrera A,Indiveri F,Ghio M

更新日期：2009-05-26 00:00:00

abstract：OBJECTIVE:To examine current vaccine sentiment on social media by constructing and analyzing semantic networks of vaccine information from highly shared websites of Twitter users in the United States; and to assist public health communication of vaccines. BACKGROUND:Vaccine hesitancy continues to contribute to subopti...

journal_title：Vaccine

authors： Kang GJ,Ewing-Nelson SR,Mackey L,Schlitt JT,Marathe A,Abbas KM,Swarup S

更新日期：2017-06-22 00:00:00

abstract：:Dengue fever and dengue hemorrhagic fever are endemic throughout tropical and subtropical countries. Four serotypes of dengue viruses (DENV-1 to DENV-4), each with several genotypes including various subclades, are co-distributed in most endemic areas. Infection-neutralizing and -enhancing antibodies are believed to p...

journal_title：Vaccine

authors： Yamanaka A,Suzuki R,Konishi E

更新日期：2014-07-23 00:00:00

abstract：:The hypervariable region 1 (HVR1) of hepatitis C virus (HCV) may contain neutralizing epitopes. A chimpanzee in whom cross-reactive anti-HVR1 antibodies had been induced by immunization was challenged with heterologous HCV for clarifying whether cross-reactive anti-HVR1 antibodies can neutralize heterologous HCV. Acut...

journal_title：Vaccine

authors： Esumi M,Zhou YH,Tanoue T,Tomoguri T,Hayasaka I

更新日期：2002-08-19 00:00:00

abstract：:Travellers often present late for the third dose of hepatitis B vaccination and measuring anti-HBs serology is common practice to ensure that these individuals are protected. We assessed the adequacy of immune response in 86 healthy travellers who had their third dose of hepatitis B (HB) vaccine performed more than 1 ...

journal_title：Vaccine

authors： Jackson Y,Chappuis F,Mezger N,Kanappa K,Loutan L

更新日期：2007-04-30 00:00:00

abstract：:The objective of this study was to evaluate different preparations of avian metapneumovirus (aMPV) subtype C as vaccine challenge in turkeys. Two aMPV isolates and their respective nasal turbinate homogenates after propagation in turkeys were used in the study. Significantly higher clinical sign scores were recorded i...

journal_title：Vaccine

authors： Velayudhan BT,Noll SL,Thachil AJ,Shaw DP,Goyal SM,Halvorson DA,Nagaraja KV

更新日期：2007-02-26 00:00:00

abstract：:Human chorionic gonadotropin (hCG) is currently under investigation as an antigenic target in both anti-cancer and anti-fertility vaccines. Formulations studied to date show promise in clinical trials for both applications yet are expensive to produce and require frequented administration in order to maintain an effec...

journal_title：Vaccine

authors： Rock EP,Reich KA,Lyu DM,Hovi M,Hardy J,Schoolnik GK,Stocker BA,Stevens V

更新日期：1996-11-01 00:00:00

abstract：:Herpes zoster, a common disease, has an important impact on the health of adults, particularly the elderly, and the health system. This study evaluated the disease burden and epidemiological characteristics of herpes zoster in Taiwan. Using herpes zoster-related ICD-9-CM codes used on Taiwan's National Health Insuranc...

journal_title：Vaccine

authors： Lin YH,Huang LM,Chang IS,Tsai FY,Lu CY,Shao PL,Chang LY,Varicella-Zoster Working Group.,Advisory Committee on Immunization Practices, Taiwan.

更新日期：2010-02-03 00:00:00

abstract：OBJECTIVES:HIV-infected children have poor responses to inactivated influenza vaccines. Live vaccines (LAIVs) are highly efficacious in children, but they are not used in HIV-infected children du e to limited information. We investigated the safety, immunogenicity and viral shedding of LAIV4 in HIV-infected compared wi...

journal_title：Vaccine

authors： Curtis D,Ning MF,Armon C,Li S,Weinberg A

更新日期：2015-09-11 00:00:00

abstract：:The availability of an inactivated hepatitis A virus (HAV) vaccine, and the development of live attenuated virus vaccines against hepatitis represent great advances in the effort to control an important cause of viral hepatitis. There are a number of ways hepatitis A vaccines could be used, depending on the epidemiolo...

journal_title：Vaccine

authors： Kane MA

更新日期：1992-01-01 00:00:00

abstract：:This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/policies/article-withdrawal. ...

journal_title：Vaccine

authors： Edouard S,Al-Tawfiq JA,Memish ZA,Yezli S,Gautret P

更新日期：2017-08-07 00:00:00

abstract：BACKGROUND:To evaluate the potential public health impact of the live attenuated tetravalent Sanofi Pasteur dengue vaccine (CYD-TDV) we analyzed data from the reported clinical trials to calculate vaccine preventable disease incidence (VPDI) and number needed to vaccinate (NNV) based on the licensure indication for per...

journal_title：Vaccine

authors： Gessner BD,Wilder-Smith A

更新日期：2016-04-29 00:00:00

abstract：BACKGROUND:Although measles is a highly infectious disease, the live measles vaccine provides protection for over 20 years, and immunity may be lifelong. This study assessed measles seroprevalence in schoolchildren in the Cochabamba region of Bolivia. METHODS:A seroepidemiological survey of measles immunity in 5-16-ye...

journal_title：Vaccine

authors： Masuet-Aumatell C,Ramon-Torrell JM,Casanova-Rituerto A,Banqué Navarro M,Dávalos Gamboa Mdel R,Montaño Rodríguez SL

更新日期：2013-04-12 00:00:00

abstract：:While health-care providers have used incentives in an attempt to motivate patients to obtain vaccinations, their effect on vaccination rates has not been systematically evaluated on a large scale. In this study, we examined whether mobile applications may improve population vaccination rates through enhanced communic...

journal_title：Vaccine

authors： Lee WN,Stück D,Konty K,Rivers C,Brown CR,Zbikowski SM,Foschini L

更新日期：2020-04-16 00:00:00

abstract：:We report that intraperitoneal injection of Chlamydia pneumoniae purified elementary bodies (EBs) in the hamster causes a systemic infection allowing the isolation of viable chlamydiae from several organs for several days post-infection (p.i.). In particular, spleen infection occurred up to Day 7 p.i. in 100% of anima...

journal_title：Vaccine

authors： Sambri V,Donati M,Storni E,Di Leo K,Agnusdei M,Petracca R,Finco O,Grandi G,Ratti G,Cevenini R

更新日期：2004-03-12 00:00:00

abstract：BACKGROUND:Sci-B-Vac® is a tri-antigenic recombinant Hepatitis B vaccine (TAV) containing the small (s), medium (pre-S2) and large (pre-S1) hepatitis B surface (HBs) antigens. To comply with vaccine licensure, a new reference standard batch was qualified by characterizing the seroprotection rate (SPR) for anti-HBs tite...

journal_title：Vaccine

authors： Atsmon J,Machluf N,Yayon-Gur V,Sabbah C,Spaans JN,Yassin-Rajkumar B,Anderson DE,Popovic V,Diaz-Mitoma F

更新日期：2021-01-13 00:00:00

abstract：:Current vaccine candidates against Rift Valley fever virus (RVFV) incorporate the viral structural glycoproteins as antigens, since triggering antibody responses against them usually correlates with protection. Here, we have focused solely on the nucleoprotein of RVFV as a potential target for vaccine development. Pre...

journal_title：Vaccine

authors： Boshra H,Lorenzo G,Rodriguez F,Brun A

更新日期：2011-06-15 00:00:00

abstract：OBJECTIVE:This case-control study investigated the relationship between the risk of Autism Spectrum Disorder (ASD) onset, and early exposure to the combined Measles-Mumps-Rubella (MMR) vaccine and thimerosal consumption measured from vaccinations in the highly genetically homogenous Japanese population. METHODS:Vaccin...

journal_title：Vaccine

authors： Uno Y,Uchiyama T,Kurosawa M,Aleksic B,Ozaki N

更新日期：2015-05-15 00:00:00

abstract：:Lactobacillus spp. comprise a large group of Gram-positive lactic acid bacteria with varying physiological, ecological and immunomodulatory properties that are widely exploited by mankind, primarily in food production and as health-promoting probiotics. Recent years have shown increased interest in using lactobacilli ...

journal_title：Vaccine

authors： Kuczkowska K,Øverland L,Rocha SDC,Eijsink VGH,Mathiesen G

更新日期：2019-10-08 00:00:00