Abstract：
:The 146S particle of the foot and mouth disease virus which is used as a vaccine antigen was found to be relatively stable when stored for prolonged periods at 4 degrees C. However, stored antigens of virus strains of the SAT serotypes but not of a virus strain of the type O serotype became less thermostable at 37 degrees C following 4 degrees C storage. Vaccines returned from the field 10 months after they were made were shown to contain significant amounts of 146S antigen of the O, A, SAT 1 and SAT 2 serotypes. Vaccine containing antigens at least 6 months old was shown to stimulate an acceptable immune response.
journal_name
Vaccinejournal_title
Vaccineauthors
Anderson EC,Doughty WJ,Muthiani Adoi
10.1016/0264-410x(83)90009-9subject
Has Abstractpub_date
1983-12-01 00:00:00pages
26-30issue
1eissn
0264-410Xissn
1873-2518pii
0264-410X(83)90009-9journal_volume
1pub_type
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