Condom use and vaginal Y-chromosome detection: the specificity of a potential biomarker.

Abstract:

OBJECTIVE:Detection of vaginal Y-chromosome sequences (YCS) may be a useful biomarker to validate sexual behavior reporting in women. We describe the effects of condom use on the detection of vaginal YCS. METHODS:Fifty-six women were asked to abstain from sexual intercourse for 14 days. On day 15, participants were asked to engage in sexual intercourse with their male partners using condoms. Self-collected vaginal swabs were obtained on days 14, 16, and 17. YCS were detected using the Roche LightCycler with the use of positive controls. RESULTS:Fourty-four of 56 women completed the study. Five women (11.4%) had detectable YCS. The overall specificity of the YCS assay with condom use was 92% (95% CI: 80%-98%). Although women who reported receptive oral sex and digital penetration within 48 hours of swab collection had a higher detection rate of YCS [RR 2.3 (95% CI: 1.1-4.6) and 3.6 (95%CI: 1.6-8.5), respectively], the mean concentration of YCS was much less than that associated with unprotected vaginal intercourse (P <0.001) CONCLUSIONS:Condom use during intercourse appears to prevent vaginal YCS detection; this may be a useful biomarker to validate self-reported condom use.

journal_name

Sex Transm Dis

authors

Ghanem KG,Melendez JH,McNeil-Solis C,Giles JA,Yuenger J,Smith TD,Zenilman J

doi

10.1097/01.olq.0000258318.99606.d9

subject

Has Abstract

pub_date

2007-08-01 00:00:00

pages

620-3

issue

8

eissn

0148-5717

issn

1537-4521

journal_volume

34

pub_type

杂志文章
  • Evidence of declining STD prevalence in a South African mining community following a core-group intervention.

    abstract:OBJECTIVES:To reduce the prevalence of curable sexually transmitted diseases (STDs) in a South African mining community through provision of STD treatment services, including periodic presumptive treatment and prevention education to a core group of high-risk women living in areas around the mines. METHODS:Women at hi...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-200001000-00001

    authors: Steen R,Vuylsteke B,DeCoito T,Ralepeli S,Fehler G,Conley J,Bruckers L,Dallabetta G,Ballard R

    更新日期:2000-01-01 00:00:00

  • Oral human papillomavirus and human herpesvirus-8 infections among human immunodeficiency virus type 1-infected men and women in Italy.

    abstract:BACKGROUND:Oral human papillomavirus (HPV) and human herpesvirus-8 (HHV8) infections are sexually transmitted and respectively associated with the development of oropharyngeal carcinoma and Kaposi sarcoma. The aim of the study was to evaluate HPV prevalence and its possible correlation with HHV8 oral shedding, in relat...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e31826ef2da

    authors: Del Mistro A,Baboci L,Frayle-Salamanca H,Trevisan R,Bergamo E,Lignitto L,Sasset L,Cecchetto MG,Cattelan AM,Calabró ML

    更新日期:2012-11-01 00:00:00

  • Sexually transmitted infections in men in Mumbai slum communities: the relationship of prevalence to risk behavior.

    abstract:OBJECTIVES:The objectives of this study were to identify sexually transmitted infection (STI) prevalence, assess behavioral and symptom correlates, and develop intervention strategies. GOAL:The goal of this study was to conduct one of the first community-based surveys of STI prevalence and risk behaviors among married...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/01.olq.0000249776.92490.32

    authors: Schensul SL,Hawkes S,Saggurti N,Verma RK,Narvekar SS,Nastasi BK,Burleson JA,Risbud A

    更新日期:2007-07-01 00:00:00

  • Men who have sex with men prefer rapid testing for syphilis and may test more frequently using it.

    abstract::Most Australian men who have sex with men who underwent rapid testing for syphilis using the Determine Syphilis TP immunoassay indicated a preference for rapid testing over conventional serology. Most also indicated that they would test for syphilis more frequently if rapid syphilis testing was available in a clinic s...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/olq.0b013e3181d707de

    authors: Lee D,Fairley C,Cummings R,Bush M,Read T,Chen M

    更新日期:2010-09-01 00:00:00

  • The estimated direct medical cost of selected sexually transmitted infections in the United States, 2008.

    abstract:BACKGROUND:Millions of cases of sexually transmitted infections (STIs) occur in the United States each year, resulting in substantial medical costs to the nation. Previous estimates of the total direct cost of STIs are quite dated. We present updated direct medical cost estimates of STIs in the United States. METHODS:...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e318285c6d2

    authors: Owusu-Edusei K Jr,Chesson HW,Gift TL,Tao G,Mahajan R,Ocfemia MC,Kent CK

    更新日期:2013-03-01 00:00:00

  • Concurrent sexual partnerships and sexually transmitted diseases in Russia.

    abstract:BACKGROUND:Sexual concurrency is associated with higher prevalence of sexually transmitted diseases (STDs) including HIV. However, most studies have focused only on the concurrency of the individual participant (individual concurrency) and not on concurrency of their sexual partners (partner concurrency). Furthermore, ...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e318205e449

    authors: Zhan W,Krasnoselskikh TV,Niccolai LM,Golovanov S,Kozlov AP,Abdala N

    更新日期:2011-06-01 00:00:00

  • Isolation of Haemophilus species from the genital tract.

    abstract::Haemophilus influenzae was isolated from the urethra of three of 85 men attending a sexually transmitted diseases clinic. These isolates of H. influenzae were nonencapsulated; one was biotype III, and two were biotype IV. Haemophilus parainfluenzae was isolated from the urethra or coronal sulcus of five men; three iso...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-198304000-00002

    authors: Messing M,Sottnek FO,Biddle JW,Schlater LK,Kramer MA,Kraus SJ

    更新日期:1983-04-01 00:00:00

  • Benefits and Potential Harms of Human Immunodeficiency Virus Self-Testing Among Men Who Have Sex With Men in China: An Implementation Perspective.

    abstract:BACKGROUND:Human immunodeficiency virus self-testing (HIVST) holds great promise for reaching high-risk key populations who do not access facility-based services. We sought to characterize unsupervised HIVST implementation among men who have sex with men in China. METHODS:We conducted a nationwide online survey in Chi...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0000000000000581

    authors: Qin Y,Tang W,Nowacki A,Mollan K,Reifeis SA,Hudgens MG,Wong NS,Li H,Tucker JD,Wei C

    更新日期:2017-04-01 00:00:00

  • Efficacy of a booster counseling session 6 months after HIV testing and counseling: a randomized, controlled trial (RESPECT-2).

    abstract:BACKGROUND:HIV counseling prevents sexually transmitted diseases (STDs), with most of the benefit accumulating in the first 6 months. STUDY:The authors conducted a multicenter, randomized, controlled trial of a 20-minute additional (booster) counseling session 6 months after HIV counseling compared with no additional ...

    journal_title:Sexually transmitted diseases

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1097/01.olq.0000151420.92624.c0

    authors: Metcalf CA,Malotte CK,Douglas JM Jr,Paul SM,Dillon BA,Cross H,Brookes LC,Deaugustine N,Lindsey CA,Byers RH,Peterman TA,RESPECT-2 Study Group.

    更新日期:2005-02-01 00:00:00

  • Evaluation of opa-based real-time PCR for detection of Neisseria gonorrhoeae.

    abstract:OBJECTIVES:Detection of Neisseria gonorrhoeae by commercial and in-house-based assays has been hampered by false-positive and false-negative results. The current study describes a sensitive and specific real-time 5'-nuclease PCR assay targeting a 90-bp region of the multicopy opa gene. GOAL:To evaluate the sensitivity...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/01.olq.0000154495.24519.bf

    authors: Tabrizi SN,Chen S,Tapsall J,Garland SM

    更新日期:2005-03-01 00:00:00

  • Sexually transmitted disease syndromes in rural South Africa. Results from health facility surveillance.

    abstract:BACKGROUND AND OBJECTIVE:Surveillance for sexually transmitted diseases (STD) is important for priority setting, service development, and evaluating interventions. GOAL:To conduct health facility-based surveillance for STDs to inform design of a control program and to provide baseline measures for evaluation of interv...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-199801000-00005

    authors: Wilkinson D,Connolly AM,Harrison A,Lurie M,Karim SS

    更新日期:1998-01-01 00:00:00

  • Patient-delivered partner treatment and other partner management strategies for sexually transmitted diseases used by New York City healthcare providers.

    abstract:OBJECTIVES:The objectives of this study were to measure frequency and predictors of patient-delivered partner treatment (PDPT) and the frequency of other partner management strategies among New York City healthcare providers (HCPs) as well as to determine whether use of PDPT detracts from other partner management strat...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/01.olq.0000225322.94613.c2

    authors: Rogers ME,Opdyke KM,Blank S,Schillinger JA

    更新日期:2007-02-01 00:00:00

  • The Estimated Lifetime Medical Cost of Chlamydia, Gonorrhea, and Trichomoniasis in the United States, 2018.

    abstract:BACKGROUND:The purpose of this study was to provide updated estimates of the average lifetime medical cost per infection for chlamydia, gonorrhea, and trichomoniasis. METHODS:We adapted a published decision tree model that allowed for 7 possible outcomes of infection: (1) symptomatic infection, treated, no sequelae; (...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0000000000001357

    authors: Kumar S,Chesson H,Spicknall IH,Kreisel K,Gift TL

    更新日期:2021-01-23 00:00:00

  • Reduction in sexual risk behaviors and infection rates among African Americans and Mexican Americans.

    abstract:BACKGROUND:Project SAFE, a gender- and culture-specific cognitive-behavioral intervention, was one of the few interventions to have demonstrated a significant reduction in sexually transmitted infections in a randomized, controlled trial. GOAL:We evaluated intervention efficacy in 379 Mexican Americans and 170 African...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/01.olq.0000115461.50698.55

    authors: Korte JE,Shain RN,Holden AE,Piper JM,Perdue ST,Champion JD,Sterneckert K

    更新日期:2004-03-01 00:00:00

  • Papillomavirus infection among abortion applicants and patients at a sexually transmitted disease clinic.

    abstract::The base-line prevalence of human papillomavirus (HPV) infection among applicants for first trimester induced abortion and among a sexually transmitted disease (STD) clinic population with macroscopically visible condyloma is investigated. Cervical cells were collected from 505 women applying for induced abortion. Cel...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:

    authors: Csángó PA,Skuland J,Nilsen A,Pedersen BS,Jagars G

    更新日期:1992-05-01 00:00:00

  • Comparison of dihydrofolate reductases from trimethoprim- and sulfonamide-resistant strains of Neisseria gonorrhoeae.

    abstract::The dihydrofolate reductases were purified from Neisseria gonorrhoeae strains CDC 9 and 7134, for which MICs of trimethoprim differ twofold and MICs of sulfadiazine differ sixtyfold. Although affinities of the dihydropteroate synthetases from the two strains for sulfonamide were known to differ markedly, no conclusive...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-197804000-00002

    authors: Ho RI,Lai PH,Corman L,Ho J,Morse SA

    更新日期:1978-04-01 00:00:00

  • Biomarkers of cervicovaginal inflammation for the assessment of microbicide safety.

    abstract::The human cervicovaginal mucosa is the primary target of HIV-1 infection during male to female transmission. This tissue contains the the full spectrum of cell types and immune modulators that comprise both the innate and adaptive arms of the immune system. Mounting evidence indicates that mucosal epithelial cells are...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章,评审

    doi:10.1097/OLQ.0b013e3181994191

    authors: Cummins JE Jr,Doncel GF

    更新日期:2009-03-01 00:00:00

  • Evaluation of self-collected versus clinician-collected swabs for the detection of Chlamydia trachomatis and Neisseria gonorrhoeae pharyngeal infection among men who have sex with men.

    abstract::We evaluated self-sampling to detect pharyngeal Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infection among men who have sex with men attending a San Francisco STD clinic. The prevalence of pharyngeal NG and CT infection was 6.7% (32/480) and 1.3% (6/480), respectively. The percent agreement between self...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e318227713e

    authors: Freeman AH,Bernstein KT,Kohn RP,Philip S,Rauch LM,Klausner JD

    更新日期:2011-11-01 00:00:00

  • From trial intervention to scale-up: costs of an adolescent sexual health program in Mwanza, Tanzania.

    abstract:OBJECTIVE:To estimate annual costs of a multifaceted adolescent sexual health intervention in Mwanza, Tanzania, by input (capital and recurrent), component (in-school, community activities, youth-friendly health services, condom distribution), and phase (development, startup, trial implementation, scale-up). STUDY DES...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/01.olq.0000200606.98181.42

    authors: Terris-Prestholt F,Kumaranayake L,Obasi AI,Cleophas-Mazige B,Makokha M,Todd J,Ross DA,Hayes RJ

    更新日期:2006-10-01 00:00:00

  • Patterns and predictors of female condom use among ethnically diverse women attending family planning clinics.

    abstract:BACKGROUND:The female condom is a viable option for women to protect themselves from HIV infection and other sexually transmitted diseases. GOAL:The goal was to examine the level of female condom use and factors associated with frequency of use among US women living in San Francisco and Oakland, California. STUDY DES...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-200301000-00018

    authors: Choi KH,Gregorich SE,Anderson K,Grinstead O,Gómez CA

    更新日期:2003-01-01 00:00:00

  • Laboratory diagnosis of gonorrhea by a simple transformation test with a temperature-sensitive mutant of Neisseria gonorrhoeae.

    abstract::A temperature-sensitive mutant of Neisseria gonorrhoeae strain tsA-1 was used in a transformation test for the laboratory diagnosis of gonorrhea. This transformation test (C test) is based on a spotting of a DNA lysate, obtained through simple base-acid extraction of a cervical-swab specimen, onto a lawn of tsA-1, whi...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-198010000-00008

    authors: Zubrzycki L,Weinberger SS

    更新日期:1980-10-01 00:00:00

  • Inhibition of active transport and macromolecular synthesis by pyocin 103 in Neisseria gonorrhoeae.

    abstract::The mechanism of inhibition of Neisseria gonorrhoeae by pyocin 103 was examined. Pyocin 103 decreases the viability of N. gonorrhoeae immediately after its addition to logarithmically growing cells by single-hit kinetics. This inhibition was paralleled by an immediate cessation of protein synthesis, RNA synthesis, and...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-198301000-00002

    authors: Stein DC,Clark VL,Young FE

    更新日期:1983-01-01 00:00:00

  • Postexposure prophylaxis for HIV in children and adolescents after sexual assault: a prospective observational study in an urban medical center.

    abstract:BACKGROUND:We sought to evaluate the tolerability and feasibility of establishing an HIV postexposure prophylaxis (PEP) program at our hospital using the guidelines for children and adolescents after sexual assault. METHODS:This study was a prospective, nonrandomized observational study conducted from March 1999 until...

    journal_title:Sexually transmitted diseases

    pub_type: 临床试验,杂志文章

    doi:10.1097/01.olq.0000225329.07765.d8

    authors: Neu N,Heffernan-Vacca S,Millery M,Stimell M,Brown J

    更新日期:2007-02-01 00:00:00

  • Association between participant self-report and biological outcomes used to measure sexual risk behavior in human immunodeficiency virus-1-seropositive female sex workers in Mombasa, Kenya.

    abstract:BACKGROUND:Few studies have examined the association between self-reported sexual risk behaviors and biologic outcomes in human immunodeficiency virus (HIV)-1-seropositive African adults. METHODS:We conducted a prospective cohort study in 898 HIV-1-seropositive women who reported engaging in transactional sex in Momba...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e31820369f6

    authors: McClelland RS,Richardson BA,Wanje GH,Graham SM,Mutunga E,Peshu N,Kiarie JN,Kurth AE,Jaoko W

    更新日期:2011-05-01 00:00:00

  • Clustering of syringe sharing and unprotected sex risk behaviors in male injecting drug users in China.

    abstract:OBJECTIVES:To investigate, among male injecting drug users (IDU), the relationships between higher risk IDU-related and sex-related behaviors. GOAL:To highlight the clustering effects of the 2 forms of risk behaviors. STUDY DESIGN:Behavioral surveillance surveys conducted in Sichuan were analyzed (n = 3105). RESULTS...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/01.olq.0000253339.49181.f9

    authors: Lau JT,Cheng F,Tsui HY,Zhang Y,Zhang J,Wang N,Zhang L

    更新日期:2007-08-01 00:00:00

  • Finding neurosyphilis without the Venereal Disease Research Laboratory test.

    abstract:BACKGROUND:The cerebrospinal fluid (CSF)-Venereal Disease Research Laboratory (VDRL) test is only 27% sensitive for diagnosing neurosyphilis. Discriminant analysis, used on 124 patients, shows that other commonly used laboratory tests can, in combination, identify 87% of patients with neurosyphilis with 94% specificity...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-199609000-00008

    authors: MacLean S,Luger A

    更新日期:1996-09-01 00:00:00

  • CXCL13 as a cerebrospinal fluid marker for neurosyphilis in HIV-infected patients with syphilis.

    abstract:BACKGROUND:Asymptomatic neurosyphilis is more difficult to diagnose in human immunodeficiency virus (HIV)-infected patients because HIV itself can cause cerebrospinal fluid (CSF) pleocytosis. The proportion of CSF lymphocytes that are B cells is elevated in neurosyphilis, suggesting that the CSF concentration of the B ...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e3181d877a1

    authors: Marra CM,Tantalo LC,Sahi SK,Maxwell CL,Lukehart SA

    更新日期:2010-05-01 00:00:00

  • The high-risk sexual practices of crack-smoking sex workers recruited from the streets of three American cities. The Multicenter Crack Cocaine and HIV Infection Study Team.

    abstract:BACKGROUND AND OBJECTIVES:Small ethnographic and clinic-based studies indicate that crack-smoking sex workers are at high risk for human immunodeficiency virus (HIV) and sexually transmitted diseases (STD). STUDY GOALS:To examine the prevalence of risky sexual behaviors and HIV and STD in a large sample of street-recr...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-199804000-00002

    authors: Jones DL,Irwin KL,Inciardi J,Bowser B,Schilling R,Word C,Evans P,Faruque S,McCoy HV,Edlin BR

    更新日期:1998-04-01 00:00:00

  • Sex in a lifetime: Sexual behaviors in the United States by lifetime number of sex partners, 2006-2010.

    abstract::Using data from the 2006-2010 National Survey of Family Growth, we found that lifetime number of vaginal sex partners is positively associated with the number of sex partners in the past 12 months and negatively associated with age at first vaginal intercourse among 15- to 44-year-old male and female respondents. ...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0000000000000132

    authors: Haderxhanaj LT,Leichliter JS,Aral SO,Chesson HW

    更新日期:2014-06-01 00:00:00

  • Understanding the Effects of Forced Sex on Sexually Transmitted Disease Acquisition and Sexually Transmitted Disease Care: Findings From the National Survey of Family Growth (2011-2013).

    abstract:BACKGROUND:Although there is evidence for heightened sexually transmitted disease (STD) acquisition among women who experienced sexual violence, little is known about their patterns of STD testing, STD diagnosis, and STD treatment. METHODS:Data was drawn from cycle eight of the National Survey of Family Growth (2011-2...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0000000000000651

    authors: Brookmeyer KA,Beltran O,Abad N

    更新日期:2017-10-01 00:00:00