Abstract:
OBJECTIVE:Detection of vaginal Y-chromosome sequences (YCS) may be a useful biomarker to validate sexual behavior reporting in women. We describe the effects of condom use on the detection of vaginal YCS. METHODS:Fifty-six women were asked to abstain from sexual intercourse for 14 days. On day 15, participants were asked to engage in sexual intercourse with their male partners using condoms. Self-collected vaginal swabs were obtained on days 14, 16, and 17. YCS were detected using the Roche LightCycler with the use of positive controls. RESULTS:Fourty-four of 56 women completed the study. Five women (11.4%) had detectable YCS. The overall specificity of the YCS assay with condom use was 92% (95% CI: 80%-98%). Although women who reported receptive oral sex and digital penetration within 48 hours of swab collection had a higher detection rate of YCS [RR 2.3 (95% CI: 1.1-4.6) and 3.6 (95%CI: 1.6-8.5), respectively], the mean concentration of YCS was much less than that associated with unprotected vaginal intercourse (P <0.001) CONCLUSIONS:Condom use during intercourse appears to prevent vaginal YCS detection; this may be a useful biomarker to validate self-reported condom use.
journal_name
Sex Transm Disjournal_title
Sexually transmitted diseasesauthors
Ghanem KG,Melendez JH,McNeil-Solis C,Giles JA,Yuenger J,Smith TD,Zenilman Jdoi
10.1097/01.olq.0000258318.99606.d9subject
Has Abstractpub_date
2007-08-01 00:00:00pages
620-3issue
8eissn
0148-5717issn
1537-4521journal_volume
34pub_type
杂志文章abstract:OBJECTIVES:To reduce the prevalence of curable sexually transmitted diseases (STDs) in a South African mining community through provision of STD treatment services, including periodic presumptive treatment and prevention education to a core group of high-risk women living in areas around the mines. METHODS:Women at hi...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200001000-00001
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Oral human papillomavirus (HPV) and human herpesvirus-8 (HHV8) infections are sexually transmitted and respectively associated with the development of oropharyngeal carcinoma and Kaposi sarcoma. The aim of the study was to evaluate HPV prevalence and its possible correlation with HHV8 oral shedding, in relat...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e31826ef2da
更新日期:2012-11-01 00:00:00
abstract:OBJECTIVES:The objectives of this study were to identify sexually transmitted infection (STI) prevalence, assess behavioral and symptom correlates, and develop intervention strategies. GOAL:The goal of this study was to conduct one of the first community-based surveys of STI prevalence and risk behaviors among married...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000249776.92490.32
更新日期:2007-07-01 00:00:00
abstract::Most Australian men who have sex with men who underwent rapid testing for syphilis using the Determine Syphilis TP immunoassay indicated a preference for rapid testing over conventional serology. Most also indicated that they would test for syphilis more frequently if rapid syphilis testing was available in a clinic s...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/olq.0b013e3181d707de
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:Millions of cases of sexually transmitted infections (STIs) occur in the United States each year, resulting in substantial medical costs to the nation. Previous estimates of the total direct cost of STIs are quite dated. We present updated direct medical cost estimates of STIs in the United States. METHODS:...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e318285c6d2
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:Sexual concurrency is associated with higher prevalence of sexually transmitted diseases (STDs) including HIV. However, most studies have focused only on the concurrency of the individual participant (individual concurrency) and not on concurrency of their sexual partners (partner concurrency). Furthermore, ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e318205e449
更新日期:2011-06-01 00:00:00
abstract::Haemophilus influenzae was isolated from the urethra of three of 85 men attending a sexually transmitted diseases clinic. These isolates of H. influenzae were nonencapsulated; one was biotype III, and two were biotype IV. Haemophilus parainfluenzae was isolated from the urethra or coronal sulcus of five men; three iso...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198304000-00002
更新日期:1983-04-01 00:00:00
abstract:BACKGROUND:Human immunodeficiency virus self-testing (HIVST) holds great promise for reaching high-risk key populations who do not access facility-based services. We sought to characterize unsupervised HIVST implementation among men who have sex with men in China. METHODS:We conducted a nationwide online survey in Chi...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000581
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:HIV counseling prevents sexually transmitted diseases (STDs), with most of the benefit accumulating in the first 6 months. STUDY:The authors conducted a multicenter, randomized, controlled trial of a 20-minute additional (booster) counseling session 6 months after HIV counseling compared with no additional ...
journal_title:Sexually transmitted diseases
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1097/01.olq.0000151420.92624.c0
更新日期:2005-02-01 00:00:00
abstract:OBJECTIVES:Detection of Neisseria gonorrhoeae by commercial and in-house-based assays has been hampered by false-positive and false-negative results. The current study describes a sensitive and specific real-time 5'-nuclease PCR assay targeting a 90-bp region of the multicopy opa gene. GOAL:To evaluate the sensitivity...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000154495.24519.bf
更新日期:2005-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Surveillance for sexually transmitted diseases (STD) is important for priority setting, service development, and evaluating interventions. GOAL:To conduct health facility-based surveillance for STDs to inform design of a control program and to provide baseline measures for evaluation of interv...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199801000-00005
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVES:The objectives of this study were to measure frequency and predictors of patient-delivered partner treatment (PDPT) and the frequency of other partner management strategies among New York City healthcare providers (HCPs) as well as to determine whether use of PDPT detracts from other partner management strat...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000225322.94613.c2
更新日期:2007-02-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to provide updated estimates of the average lifetime medical cost per infection for chlamydia, gonorrhea, and trichomoniasis. METHODS:We adapted a published decision tree model that allowed for 7 possible outcomes of infection: (1) symptomatic infection, treated, no sequelae; (...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000001357
更新日期:2021-01-23 00:00:00
abstract:BACKGROUND:Project SAFE, a gender- and culture-specific cognitive-behavioral intervention, was one of the few interventions to have demonstrated a significant reduction in sexually transmitted infections in a randomized, controlled trial. GOAL:We evaluated intervention efficacy in 379 Mexican Americans and 170 African...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000115461.50698.55
更新日期:2004-03-01 00:00:00
abstract::The base-line prevalence of human papillomavirus (HPV) infection among applicants for first trimester induced abortion and among a sexually transmitted disease (STD) clinic population with macroscopically visible condyloma is investigated. Cervical cells were collected from 505 women applying for induced abortion. Cel...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:
更新日期:1992-05-01 00:00:00
abstract::The dihydrofolate reductases were purified from Neisseria gonorrhoeae strains CDC 9 and 7134, for which MICs of trimethoprim differ twofold and MICs of sulfadiazine differ sixtyfold. Although affinities of the dihydropteroate synthetases from the two strains for sulfonamide were known to differ markedly, no conclusive...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-197804000-00002
更新日期:1978-04-01 00:00:00
abstract::The human cervicovaginal mucosa is the primary target of HIV-1 infection during male to female transmission. This tissue contains the the full spectrum of cell types and immune modulators that comprise both the innate and adaptive arms of the immune system. Mounting evidence indicates that mucosal epithelial cells are...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,评审
doi:10.1097/OLQ.0b013e3181994191
更新日期:2009-03-01 00:00:00
abstract::We evaluated self-sampling to detect pharyngeal Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infection among men who have sex with men attending a San Francisco STD clinic. The prevalence of pharyngeal NG and CT infection was 6.7% (32/480) and 1.3% (6/480), respectively. The percent agreement between self...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e318227713e
更新日期:2011-11-01 00:00:00
abstract:OBJECTIVE:To estimate annual costs of a multifaceted adolescent sexual health intervention in Mwanza, Tanzania, by input (capital and recurrent), component (in-school, community activities, youth-friendly health services, condom distribution), and phase (development, startup, trial implementation, scale-up). STUDY DES...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000200606.98181.42
更新日期:2006-10-01 00:00:00
abstract:BACKGROUND:The female condom is a viable option for women to protect themselves from HIV infection and other sexually transmitted diseases. GOAL:The goal was to examine the level of female condom use and factors associated with frequency of use among US women living in San Francisco and Oakland, California. STUDY DES...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200301000-00018
更新日期:2003-01-01 00:00:00
abstract::A temperature-sensitive mutant of Neisseria gonorrhoeae strain tsA-1 was used in a transformation test for the laboratory diagnosis of gonorrhea. This transformation test (C test) is based on a spotting of a DNA lysate, obtained through simple base-acid extraction of a cervical-swab specimen, onto a lawn of tsA-1, whi...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198010000-00008
更新日期:1980-10-01 00:00:00
abstract::The mechanism of inhibition of Neisseria gonorrhoeae by pyocin 103 was examined. Pyocin 103 decreases the viability of N. gonorrhoeae immediately after its addition to logarithmically growing cells by single-hit kinetics. This inhibition was paralleled by an immediate cessation of protein synthesis, RNA synthesis, and...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198301000-00002
更新日期:1983-01-01 00:00:00
abstract:BACKGROUND:We sought to evaluate the tolerability and feasibility of establishing an HIV postexposure prophylaxis (PEP) program at our hospital using the guidelines for children and adolescents after sexual assault. METHODS:This study was a prospective, nonrandomized observational study conducted from March 1999 until...
journal_title:Sexually transmitted diseases
pub_type: 临床试验,杂志文章
doi:10.1097/01.olq.0000225329.07765.d8
更新日期:2007-02-01 00:00:00
abstract:BACKGROUND:Few studies have examined the association between self-reported sexual risk behaviors and biologic outcomes in human immunodeficiency virus (HIV)-1-seropositive African adults. METHODS:We conducted a prospective cohort study in 898 HIV-1-seropositive women who reported engaging in transactional sex in Momba...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e31820369f6
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVES:To investigate, among male injecting drug users (IDU), the relationships between higher risk IDU-related and sex-related behaviors. GOAL:To highlight the clustering effects of the 2 forms of risk behaviors. STUDY DESIGN:Behavioral surveillance surveys conducted in Sichuan were analyzed (n = 3105). RESULTS...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000253339.49181.f9
更新日期:2007-08-01 00:00:00
abstract:BACKGROUND:The cerebrospinal fluid (CSF)-Venereal Disease Research Laboratory (VDRL) test is only 27% sensitive for diagnosing neurosyphilis. Discriminant analysis, used on 124 patients, shows that other commonly used laboratory tests can, in combination, identify 87% of patients with neurosyphilis with 94% specificity...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199609000-00008
更新日期:1996-09-01 00:00:00
abstract:BACKGROUND:Asymptomatic neurosyphilis is more difficult to diagnose in human immunodeficiency virus (HIV)-infected patients because HIV itself can cause cerebrospinal fluid (CSF) pleocytosis. The proportion of CSF lymphocytes that are B cells is elevated in neurosyphilis, suggesting that the CSF concentration of the B ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e3181d877a1
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Small ethnographic and clinic-based studies indicate that crack-smoking sex workers are at high risk for human immunodeficiency virus (HIV) and sexually transmitted diseases (STD). STUDY GOALS:To examine the prevalence of risky sexual behaviors and HIV and STD in a large sample of street-recr...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199804000-00002
更新日期:1998-04-01 00:00:00
abstract::Using data from the 2006-2010 National Survey of Family Growth, we found that lifetime number of vaginal sex partners is positively associated with the number of sex partners in the past 12 months and negatively associated with age at first vaginal intercourse among 15- to 44-year-old male and female respondents. ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000132
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND:Although there is evidence for heightened sexually transmitted disease (STD) acquisition among women who experienced sexual violence, little is known about their patterns of STD testing, STD diagnosis, and STD treatment. METHODS:Data was drawn from cycle eight of the National Survey of Family Growth (2011-2...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000651
更新日期:2017-10-01 00:00:00