Benefits and Potential Harms of Human Immunodeficiency Virus Self-Testing Among Men Who Have Sex With Men in China: An Implementation Perspective.

Abstract:

BACKGROUND:Human immunodeficiency virus self-testing (HIVST) holds great promise for reaching high-risk key populations who do not access facility-based services. We sought to characterize unsupervised HIVST implementation among men who have sex with men in China. METHODS:We conducted a nationwide online survey in China. Eligible men were at least 16 years, had anal sex with a man, and had recent condomless sex. We assessed benefits (first-time testing, increased testing frequency, confirmatory testing) and potential harms (coercion, violence, suicidality) of HIVST. Among men who have sex with men who reported ever testing for human immunodeficiency virus (HIV), we identified correlates of HIVST as first-time HIV test being a self-test using multivariable logistic regression. RESULTS:Among 1610 men who met the eligibility criteria and started the survey, 1189 (74%) completed it. Three hundred forty-one (29%) of 1189 reported ever self-testing for HIV. Human immunodeficiency virus prevalence was 7% (24/341) among self-testers and 5% (15/306) among non-self-testers. Two hundred (59%) of 341 men who self-tested reported HIVST as a first-time HIV test. Thirty-one (9%) men experienced coercion with HIVST. Thirty-one (78%) of 40 men with positive HIV self-tests sought confirmation. Multivariable analysis revealed that HIVST as first-time HIV test was associated with younger age (odds ratio [OR], 0.95; 95% confidence interval [CI], 0.92-0.99), not being "out" (OR, 2.28; 95% CI, 1.60-3.28), not using the internet to meet sex partners (OR, 0.39; 95% CI, 0.22-0.69), and group sex (OR, 1.74; 95% CI, 1.02-2.9). CONCLUSIONS:Human immunodeficiency virus self-testing reached high-risk individuals that had never received facility-based testing. Further implementation research is needed to better understand HIVST outside of research programs.

journal_name

Sex Transm Dis

authors

Qin Y,Tang W,Nowacki A,Mollan K,Reifeis SA,Hudgens MG,Wong NS,Li H,Tucker JD,Wei C

doi

10.1097/OLQ.0000000000000581

subject

Has Abstract

pub_date

2017-04-01 00:00:00

pages

233-238

issue

4

eissn

0148-5717

issn

1537-4521

pii

00007435-201704000-00008

journal_volume

44

pub_type

杂志文章
  • Coital bleeding and HIV risks among men and women in Cape Town, South Africa.

    abstract:BACKGROUND:South Africa has one of the world's fastest growing HIV epidemics. Genital bleeding during sexual intercourse may play a role in facilitating HIV transmission in South Africa. PURPOSE:The purpose of this study was to examine the prevalence and sources of coital bleeding among men and women living in a Cape ...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/01.olq.0000218868.76820.7f

    authors: Kalichman SC,Simbayi LC,Cain D,Cherry C,Jooste S

    更新日期:2006-09-01 00:00:00

  • Duplex real-time polymerase chain reaction assay for detection and quantification of herpes simplex virus type 1 and herpes simplex virus type 2 in genital and cutaneous lesions.

    abstract:BACKGROUND:A sensitive and specific method for detecting herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2) is important for diagnosing genital and cutaneous infections. GOAL:The goal of this study was to compare quantitative real-time polymerase chain reaction (qPCR) with virus culture for di...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-200406000-00002

    authors: Filén F,Strand A,Allard A,Blomberg J,Herrmann B

    更新日期:2004-06-01 00:00:00

  • Etiology of acute pelvic inflammatory disease proven by laparoscopy.

    abstract:BACKGROUND:Only a few studies have investigated the etiology of acute pelvic inflammatory disease (PID) in laparoscopy-proven cases using pelvic samples for culture. Most of these studies were conducted in North America and Scandinavia. GOAL OF THE STUDY:To study the microbial etiology of laparoscopy-proven acute pelv...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-199305000-00008

    authors: Dan M,Samra Z,Katz A,Debby A,Gutman R,Zakut H

    更新日期:1993-05-01 00:00:00

  • Limitations of the dye-based method for determining vaginal applicator use in microbicide trials.

    abstract:BACKGROUND:A dye-based method for determining applicator usage in microbicide trials has been developed to assess whether applicators have been exposed to vaginal fluid. Our objective was to evaluate this method on polypropylene HTI applicators that are being widely used in several effectiveness trials of microbicides....

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章,多中心研究

    doi:10.1097/OLQ.0b013e3181972397

    authors: Austin MN,Rabe LK,Hillier SL

    更新日期:2009-06-01 00:00:00

  • Suppressive valacyclovir therapy: impact on the population spread of HSV-2 infection.

    abstract:OBJECTIVES:Recent trial results demonstrate that the transmission probability of HSV-2 in monogamous couples is nearly halved by the use of valacyclovir as suppressive therapy. GOAL:The goal of this study is to understand the potential impact of suppressive valacyclovir therapy on the transmission of HSV-2 within a po...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/01.olq.0000258486.81492.a2

    authors: Williams JR,Jordan JC,Davis EA,Garnett GP

    更新日期:2007-03-01 00:00:00

  • Validity of self-reported sexually transmitted diseases among African American female adolescents participating in an HIV/STD prevention intervention trial.

    abstract:BACKGROUND:Studies assessing the validity attributed to self-reported measures of sexually transmitted diseases (STDs) clearly are needed, particularly those used for high-risk populations such as female adolescents, in whom STD prevention is a priority. GOAL:To determine the accuracy of self-reported STD test results...

    journal_title:Sexually transmitted diseases

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1097/00007435-200108000-00009

    authors: Harrington KF,DiClemente RJ,Wingood GM,Crosby RA,Person S,Oh MK,Hook EW 3rd

    更新日期:2001-08-01 00:00:00

  • Sex and disease. Playing the odds in the 1990s.

    abstract::Selected results from a recent study on sexual behavior in the United States are presented, focusing on the association between sexual behavior, disease prevention, and STD outcome. The data are from national household samples of adult men and women. The results show that a sizeable proportion of the U.S. adult popula...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:

    authors: Tanfer K

    更新日期:1994-03-01 00:00:00

  • Measuring the in vitro susceptibility of Trichomonas vaginalis to metronidazole: a disk broth method.

    abstract::Strains of Trichomonas vaginalis were evaluated for their in vitro responses to metronidazole. A serial twofold dilution method that measured minimal inhibitory concentrations (MICs) by cessation of trophozoite motility was compared with the disk broth method, in which both cessation of motility and inhibition of trop...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-198007000-00005

    authors: Smith RF,Di Domenico A

    更新日期:1980-07-01 00:00:00

  • Predicting Neisseria gonorrhoeae and Chlamydia trachomatis infection using risk scores, physical examination, microscopy, and leukocyte esterase urine dipsticks among asymptomatic women attending a family planning clinic in Kenya.

    abstract:BACKGROUND:Sexually transmitted infections (STIs) continue to exert a tremendous health burden on women in developing countries. Poor socioeconomic status, inadequate knowledge, lack of diagnostic facilities, and shortages of effective treatment all contribute to the high incidence of STIs. The use of clinical algorith...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-199909000-00010

    authors: Tyndall MW,Kidula N,Sande J,Ombette J,Temmerman M

    更新日期:1999-09-01 00:00:00

  • Comparison of cefpimizole with cefotaxime and penicillin G for treatment of uncomplicated gonorrhea.

    abstract::One hundred sixteen patients (92 men and 24 women) with suspected uncomplicated gonorrhea were randomized in a double-blind manner to receive intramuscular treatment with 1.0 g of cefpimizole, 1.0 g of cefotaxime, or 4.8 x 10(6) units of aqueous procaine penicillin G (APPG) with 1 g of oral probenecid. Seventeen perce...

    journal_title:Sexually transmitted diseases

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00007435-198804000-00001

    authors: Raad II,Sherertz RJ,Loveless MO,Carillo C,O'Connor RP,Miller M,Mostow SR

    更新日期:1988-04-01 00:00:00

  • Susceptibility to vaccine-preventable diseases in a sexually transmitted disease clinic population.

    abstract:BACKGROUND AND OBJECTIVE:Sexually transmitted disease (STD) clinics often serve a population that has low medical care utilization. The objective of this study was to determine the susceptibility of an STD clinic population to vaccine-preventable diseases. STUDY DESIGN:A cross-sectional study of immunization practices...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-199808000-00001

    authors: Staat MA,Tang YL,Fresia AE,Halsey N,Kacergis J,Zenilman J

    更新日期:1998-08-01 00:00:00

  • Ending the HIV Epidemic: Contributions Resulting From Syphilis Partner Services.

    abstract:BACKGROUND:There is a high level of coinfection with human immunodeficiency virus (HIV) among persons diagnosed with syphilis in the United States. Public health workers at state and local health departments help inform exposed partners to sexually transmitted disease (STD)/HIV infections to facilitate early testing an...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0000000000001201

    authors: DiOrio D,Collins D,Hanley S

    更新日期:2020-08-01 00:00:00

  • Willingness to Disclose Sexually Transmitted Infection Status to Sex Partners Among College-Aged Men in the United States.

    abstract::Disclosure of sexually transmitted infections (STIs) to sexual partners is critical to the prevention, treatment, and control of STIs. We examine personal intra and interpersonal influences on willingness to disclose STI status among college-aged men. Participants (n = 1064) were aged 17 to 24 years and recruited from...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0000000000000420

    authors: Pfeiffer EJ,McGregor KA,Van Der Pol B,Hardy Hansen C,Ott MA

    更新日期:2016-03-01 00:00:00

  • Cervical intraepithelial neoplasia is associated with genital tract mucosal inflammation.

    abstract:BACKGROUND:Clinical studies demonstrate increased prevalence of human papillomavirus (HPV)-associated disease in HIV-infected individuals and an increased risk of HIV acquisition in HPV-infected individuals. The mechanisms underlying this synergy are not defined. We hypothesize that women with cervical intraepithelial ...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e318255aeef

    authors: Mhatre M,McAndrew T,Carpenter C,Burk RD,Einstein MH,Herold BC

    更新日期:2012-08-01 00:00:00

  • Efficacy of a booster counseling session 6 months after HIV testing and counseling: a randomized, controlled trial (RESPECT-2).

    abstract:BACKGROUND:HIV counseling prevents sexually transmitted diseases (STDs), with most of the benefit accumulating in the first 6 months. STUDY:The authors conducted a multicenter, randomized, controlled trial of a 20-minute additional (booster) counseling session 6 months after HIV counseling compared with no additional ...

    journal_title:Sexually transmitted diseases

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1097/01.olq.0000151420.92624.c0

    authors: Metcalf CA,Malotte CK,Douglas JM Jr,Paul SM,Dillon BA,Cross H,Brookes LC,Deaugustine N,Lindsey CA,Byers RH,Peterman TA,RESPECT-2 Study Group.

    更新日期:2005-02-01 00:00:00

  • Estimating the Total Annual Direct Cost of Providing Sexually Transmitted Infection and HIV Testing and Counseling for Men Who Have Sex With Men in the United States.

    abstract:BACKGROUND:The Centers for Disease Control and Prevention recommends annual sexually transmitted infection (STI) and HIV testing and counseling for men who have sex with men (MSM) in the United States. We estimated the annual total direct medical cost of providing recommended STI and HIV testing and counseling services...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0000000000000341

    authors: Owusu-Edusei K Jr,Gift TL,Patton ME,Johnson DB,Valentine JA

    更新日期:2015-10-01 00:00:00

  • Laboratory diagnosis of gonorrhea by a simple transformation test with a temperature-sensitive mutant of Neisseria gonorrhoeae.

    abstract::A temperature-sensitive mutant of Neisseria gonorrhoeae strain tsA-1 was used in a transformation test for the laboratory diagnosis of gonorrhea. This transformation test (C test) is based on a spotting of a DNA lysate, obtained through simple base-acid extraction of a cervical-swab specimen, onto a lawn of tsA-1, whi...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-198010000-00008

    authors: Zubrzycki L,Weinberger SS

    更新日期:1980-10-01 00:00:00

  • Sexually transmitted diseases and risk behaviors among pregnant women attending inner city public sexually transmitted diseases clinics in Baltimore, MD, 1996-2002.

    abstract:OBJECTIVE:To determine the prevalence of sexually transmitted diseases (STDs) and characterize behavioral correlates among pregnant women attending inner city public STD clinics. STUDY DESIGN:A retrospective study of 2303 pregnant women frequency matched by clinic and year of visit to 2303 nonpregnant women seeking se...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/olq.0b013e31812e6b9a

    authors: Johnson HL,Erbelding EJ,Zenilman JM,Ghanem KG

    更新日期:2007-12-01 00:00:00

  • HIV Testing, HIV Positivity, and Linkage and Referral Services in Correctional Facilities in the United States, 2009-2013.

    abstract:BACKGROUND:Because of health disparities, incarcerated persons are at higher risk for multiple health issues, including HIV. Correctional facilities have an opportunity to provide HIV services to an underserved population. This article describes Centers for Disease Control and Prevention (CDC)-funded HIV testing and se...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0000000000000353

    authors: Seth P,Figueroa A,Wang G,Reid L,Belcher L

    更新日期:2015-11-01 00:00:00

  • Performance of Commercial Enzyme-Linked Immunoassays for Diagnosis of Herpes Simplex Virus-1 and Herpes Simplex Virus-2 Infection in a Clinical Setting.

    abstract:BACKGROUND:US Food and Drug Administration-approved enzyme-linked immunoassays (EIA) for determining type-specific herpes simplex virus (HSV) serostatus are widely used in clinical practice. We compared the performance of such assays with the University of Washington Western blot (UW WB) in patients who sought confirma...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0000000000000689

    authors: Agyemang E,Le QA,Warren T,Magaret AS,Selke S,Johnston C,Jerome KR,Wald A

    更新日期:2017-12-01 00:00:00

  • A Retrospective Review of Treatment Failures Using Azithromycin and Doxycycline in the Treatment of Rectal Chlamydia Infections in Women and Men Who Have Sex With Men.

    abstract::We examined the prevalence of rectal chlamydia treatment failures in men who have sex with men and women attending Alberta sexually transmitted infection clinics. Among those completing a test of cure, there was no significant difference among patients treated initially with azithromycin (treatment failure, 39/460 [8....

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0000000000000403

    authors: Gratrix J,Brandley J,Dane M,Plitt SS,Smyczek P,Read R,Singh AE

    更新日期:2016-02-01 00:00:00

  • Prevalence and risk factors for human herpesvirus 8 infection in northern Cameroon.

    abstract:BACKGROUND:The modes of transmission of HHV-8 are still unclear. GOAL:To evaluate the distribution and transmission of HHV-8 infection. DESIGN:Serosurvey conducted in a Cameroon hospital among 292 persons, including children (5-10 years), adolescents (15-20 years), and adults (30-40 years). Antibodies against lytic a...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-200003000-00008

    authors: Rezza G,Tchangmena OB,Andreoni M,Bugarini R,Toma L,Bakary DK,Glikoutou M,Sarmati L,Monini P,Pezzotti P,Ensoli B

    更新日期:2000-03-01 00:00:00

  • Sexual transmission of hepatitis C virus from a patient with chronic disease to his sex partner after removal of an intrauterine device.

    abstract:BACKGROUND:Approximately 40% of patients infected with hepatitis C virus (HCV) have no history of blood transfusion or other high-risk practice. Other causes should be considered. GOAL:The goal was to describe sexual transmission of HCV from a chronic carrier to his female partner during unprotected vaginal intercours...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-200305000-00015

    authors: Quer J,Murillo P,Esteban JI,Martell M,Esteban R,Guardia J

    更新日期:2003-05-01 00:00:00

  • Reinfections, persistent infections, and new infections after general population screening for Chlamydia trachomatis infection in the Netherlands.

    abstract:OBJECTIVES:The objectives of this study were to determine the rate of new infections and reinfections or persistent infections with Chlamydia trachomatis to define appropriate screening intervals and to identify risk factors for reinfection. DESIGN:This was a cross-sectional study among a subsample of participants in ...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/01.olq.0000179887.01141.c3

    authors: Veldhuijzen IK,Van Bergen JE,Götz HM,Hoebe CJ,Morré SA,Richardus JH,PILOT CT Study Group.

    更新日期:2005-10-01 00:00:00

  • Integrating hepatitis B prevention into sexually transmitted disease services: U.S. sexually transmitted disease program and clinic trends--1997 and 2001.

    abstract:OBJECTIVE:The objective of this study was to measure the progress since 1997 of implementing sexually transmitted disease (STD) clinic-based recommendations for hepatitis B prevention. GOAL:The goal of this study was to assess improvements since 1997 in hepatitis B prevention integration in STD services. STUDY:Repeat...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/01.olq.0000154503.41684.5d

    authors: Gilbert LK,Bulger J,Scanlon K,Ford K,Bergmire-Sweat D,Weinbaum C

    更新日期:2005-06-01 00:00:00

  • Interrelationships of bacterial vaginosis and cervical inflammation.

    abstract:BACKGROUND:Women with cervicitis frequently have bacterial vaginosis (BV). Prior studies have suggested that BV is involved in the pathogenesis of cervicitis. GOALS:To delineate the association of BV and cervicitis and to determine whether treatment of BV results in increased resolution of cervicitis. STUDY DESIGN:Wo...

    journal_title:Sexually transmitted diseases

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00007435-200201000-00010

    authors: Schwebke JR,Weiss HL

    更新日期:2002-01-01 00:00:00

  • Susceptibility of Chlamydia trachomatis to antibiotics in vitro and in vivo.

    abstract::The susceptibility of Chlamydia trachomatis to antibiotics was studied in vitro and in patients with nongonococcal urethritis. The minimal inhibitory concentrations of cloxacillin, erythromycin, pivampicillin, oxytetracycline, and doxycycline, which were the most effective drugs, were 10, 0.5, 0.25, 0.1, and 0.5 micro...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-197904000-00002

    authors: Johannisson G,Sernryd A,Lycke E

    更新日期:1979-04-01 00:00:00

  • Partner referral by patients with gonorrhea and chlamydial infection. Case-finding observations.

    abstract:OBJECTIVE:To evaluate the outcomes of a partner referral program at the sexually transmitted disease (STD) clinic in Amsterdam that encourages gonorrhea and chlamydia patients to refer their own partners to medical examination. STUDY DESIGN:355 patients with a confirmed infection cooperated in partner referral and gav...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-199707000-00005

    authors: van de Laar MJ,Termorshuizen F,van den Hoek A

    更新日期:1997-07-01 00:00:00

  • Condoms for men, not women. Results of brief promotion programs.

    abstract::Three different brief intervention programs to promote condom use were tested among patients in inner-city sexually transmitted disease (STD) clinics. The first, "Condom Skills," focused on teaching mechanical aspects of how to use a condom. The second, "Social Influences," emphasized how to negotiate condom use with ...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-199209000-00002

    authors: Cohen DA,Dent C,MacKinnon D,Hahn G

    更新日期:1992-09-01 00:00:00

  • Oral human papillomavirus and human herpesvirus-8 infections among human immunodeficiency virus type 1-infected men and women in Italy.

    abstract:BACKGROUND:Oral human papillomavirus (HPV) and human herpesvirus-8 (HHV8) infections are sexually transmitted and respectively associated with the development of oropharyngeal carcinoma and Kaposi sarcoma. The aim of the study was to evaluate HPV prevalence and its possible correlation with HHV8 oral shedding, in relat...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e31826ef2da

    authors: Del Mistro A,Baboci L,Frayle-Salamanca H,Trevisan R,Bergamo E,Lignitto L,Sasset L,Cecchetto MG,Cattelan AM,Calabró ML

    更新日期:2012-11-01 00:00:00