Abstract:
:Strains of Trichomonas vaginalis were evaluated for their in vitro responses to metronidazole. A serial twofold dilution method that measured minimal inhibitory concentrations (MICs) by cessation of trophozoite motility was compared with the disk broth method, in which both cessation of motility and inhibition of trophozoite proliferation were used for measurement of MICs. These methods gave comparable results in distinguishing a metronidazole-resistant and two metronidazole-susceptible strains of T. vaginalis under conditions of both aerobic and anaerobic incubation. However, anaerobic test conditions significantly lowered the MIC of metronidazole against a metronidazole-resistant strain. Clinical isolates of T. vaginalis and strain ATCC 30001 from the American Type Culture Collection (Rockville, Md.) were also tested. Two of 12 clinical isolates were resistant to metronidazole in vitro. It is concluded that the disk broth method is a simple and reliable screening method for detection of metronidazole-resistant strains of T. vaginalis.
journal_name
Sex Transm Disjournal_title
Sexually transmitted diseasesauthors
Smith RF,Di Domenico Adoi
10.1097/00007435-198007000-00005subject
Has Abstractpub_date
1980-07-01 00:00:00pages
120-4issue
3eissn
0148-5717issn
1537-4521journal_volume
7pub_type
杂志文章abstract::A new variant of Chlamydia trachomatis (nvCT) was discovered in Sweden in 2006, and it could not be detected by diagnostic systems from Abbott and Roche, whereas the third system used, from Becton Dickinson (BD), detects nvCT. We analyzed 3648 samples from 2 counties that used Roche and 2 counties that used BD methods...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e3182593be7
更新日期:2012-08-01 00:00:00
abstract::The patterns of electrophoretic (SDS-PAGE) migration of the major outer membrane protein I of 35 strains of Neisseria gonorrhoeae causing disseminated gonococcal infections (DGI) were compared, and the proportion of colonies expressing the transparent phenotype on a solid medium was determined. Thirty-one of these DGI...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198604000-00003
更新日期:1986-04-01 00:00:00
abstract::The susceptibility of Chlamydia trachomatis to antibiotics was studied in vitro and in patients with nongonococcal urethritis. The minimal inhibitory concentrations of cloxacillin, erythromycin, pivampicillin, oxytetracycline, and doxycycline, which were the most effective drugs, were 10, 0.5, 0.25, 0.1, and 0.5 micro...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-197904000-00002
更新日期:1979-04-01 00:00:00
abstract::High-performance liquid chromatography was used for quantitative determination of podophyllotoxin in serum subsequent to repeated applications of a 0.5% ethanolic preparation on condylomata acuminata. The drug was not detectable in the serum of ten men treated with < or = 50 microliters. In serum of seven patients rec...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:
更新日期:1982-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Methods of HIV and STD prevention, which can be controlled by the receptive partner, are a high priority for research and development. Studies on the safety of Nonoxynol-9 (N-9) on the vaginal mucosa have yielded conflicting results. No Phase I study has evaluated the effect of N-9 on the rect...
journal_title:Sexually transmitted diseases
pub_type: 临床试验,杂志文章
doi:10.1097/00007435-199911000-00005
更新日期:1999-11-01 00:00:00
abstract::The objective of this study was to develop and apply a serologic method for identification of different strains of Neisseria gonorrhoeae. Several procedures for preparation of cell-free extracts were tried; the most satisfactory was that with phosphate-buffered saline solution. Both capillary tube and immunodiffusion ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198004000-00002
更新日期:1980-04-01 00:00:00
abstract:BACKGROUND:Sexually transmitted infections (STIs) continue to exert a tremendous health burden on women in developing countries. Poor socioeconomic status, inadequate knowledge, lack of diagnostic facilities, and shortages of effective treatment all contribute to the high incidence of STIs. The use of clinical algorith...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199909000-00010
更新日期:1999-09-01 00:00:00
abstract::Heretofore most people affected by warts of the oral cavity were children, but during the past decade adults have become the most frequently seen patients with warts in the mouth. The popularity of fellatio among heterosexuals, teenagers, and adults has contributed to the spread of oral warts. Of epidemiologic interes...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198410000-00001
更新日期:1984-10-01 00:00:00
abstract:BACKGROUND:South Africa has one of the world's fastest growing HIV epidemics. Genital bleeding during sexual intercourse may play a role in facilitating HIV transmission in South Africa. PURPOSE:The purpose of this study was to examine the prevalence and sources of coital bleeding among men and women living in a Cape ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000218868.76820.7f
更新日期:2006-09-01 00:00:00
abstract:BACKGROUND:Alcohol use has been linked to risky sexual practices among adolescents. However, limited research on alcohol use and risky sexual behavior has been conducted on African-American female adolescents. This study examined high quantity of alcohol as a longitudinal predictor of risky sexual behavior and sexually...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e3181f07abe
更新日期:2011-02-01 00:00:00
abstract::The Division of Venereal Disease Control in British Columbia undertook a three-year, $235,000 advertising campaign to increase demand for information on sexually transmitted disease, increase clinic attendance, and decrease the incidence of gonorrhea. As a result of the campaign, demand for information increased, and ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198207000-00002
更新日期:1982-07-01 00:00:00
abstract:BACKGROUND:Herpes simplex virus type 2 (HSV-2) is an important cause of genital ulcers and can increase the risk for human immunodeficiency virus type 1 (HIV-1) transmission. Our objective was to determine the incidence and correlates of HSV-2 infection in HIV-1-seronegative Kenyan men reporting high-risk sexual behavi...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e31821a6225
更新日期:2011-09-01 00:00:00
abstract::Both neurosyphilis and diplopia are widely known medical terms. Nevertheless, low clinical awareness by the physician and the often-overlooked presentation of diplopia, make the combination of neurosyphilis and diplopia rarely observed. In this article, we report 2 neurosyphilitic patients presenting with diplopia and...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,评审
doi:10.1097/OLQ.0000000000000703
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:The association between area-based social factors and sexually transmitted diseases has been demonstrated in numerous studies. Such associations have not previously been explored for their potential to quantify likelihood of higher transmission of gonorrhea in small geographic areas. METHODS:Aggregate censu...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,多中心研究
doi:10.1097/OLQ.0000000000000195
更新日期:2014-11-01 00:00:00
abstract::60 women with bacterial vaginosis were entered into a double blind, placebo-controlled treatment trial with lyophilized Lactobacillus acidophilus. The lactobacilli used were producing H2O2. Immediately after completion of treatment, 16 out of 28 women who were treated with lactobacilli had normal vaginal wet smear res...
journal_title:Sexually transmitted diseases
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00007435-199205000-00007
更新日期:1992-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The goal of this study was to examine the relationship between contraceptive method choice and perceptions of HIV and pregnancy risk among women at risk of HIV infection and transmission. STUDY DESIGN:Women who were infected with HIV or who were at high risk of infection were administered a q...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199401000-00002
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND:Although there is evidence for heightened sexually transmitted disease (STD) acquisition among women who experienced sexual violence, little is known about their patterns of STD testing, STD diagnosis, and STD treatment. METHODS:Data was drawn from cycle eight of the National Survey of Family Growth (2011-2...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000651
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:The development of topical microbicides represents a new and exciting field in the prevention of sexually transmitted diseases, and it is especially important that candidate products undergo rigorous preclinical safety and efficacy testing before advancing to clinical trials. METHODS:We have developed a sta...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e31817dfdb8
更新日期:2008-10-01 00:00:00
abstract:OBJECTIVE:Detection of vaginal Y-chromosome sequences (YCS) may be a useful biomarker to validate sexual behavior reporting in women. We describe the effects of condom use on the detection of vaginal YCS. METHODS:Fifty-six women were asked to abstain from sexual intercourse for 14 days. On day 15, participants were as...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000258318.99606.d9
更新日期:2007-08-01 00:00:00
abstract::One hundred sixteen patients (92 men and 24 women) with suspected uncomplicated gonorrhea were randomized in a double-blind manner to receive intramuscular treatment with 1.0 g of cefpimizole, 1.0 g of cefotaxime, or 4.8 x 10(6) units of aqueous procaine penicillin G (APPG) with 1 g of oral probenecid. Seventeen perce...
journal_title:Sexually transmitted diseases
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00007435-198804000-00001
更新日期:1988-04-01 00:00:00
abstract::We examined the prevalence of rectal chlamydia treatment failures in men who have sex with men and women attending Alberta sexually transmitted infection clinics. Among those completing a test of cure, there was no significant difference among patients treated initially with azithromycin (treatment failure, 39/460 [8....
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000403
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Approximately 40% of patients infected with hepatitis C virus (HCV) have no history of blood transfusion or other high-risk practice. Other causes should be considered. GOAL:The goal was to describe sexual transmission of HCV from a chronic carrier to his female partner during unprotected vaginal intercours...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200305000-00015
更新日期:2003-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Trichomonas vaginalis is one of the most common sexually transmitted infections. In Malawi, rates of trichomoniasis in women are high. The prevalence of T. vaginalis infection in men is expected to be high but has not previously been documented. GOALS:We sought to determine the prevalence of ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199908000-00003
更新日期:1999-08-01 00:00:00
abstract:BACKGROUND:Men who have sex with men (MSM) are the largest human immunodeficiency virus (HIV) risk group in the United States. Sexual concurrency may contribute to high HIV incidence or to racial/ethnic HIV disparities among MSM. Limited information is available on concurrency and racial/ethnic differences among MSM or...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e31825ec09b
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:Black race is a risk marker for Chlamydia trachomatis infection. Because chlamydial serovar and race could both influence the transmission dynamics of chlamydia, studies characterizing serovars in a predominantly black population are of interest, yet remain sparse. STUDY DESIGN AND GOALS: C. trachomatis isol...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000216027.71144.74
更新日期:2006-10-01 00:00:00
abstract:OBJECTIVE:Risk factors for bacterial vaginosis (BV) include douching and sexual activity, although the exact cause of BV is unknown. GOAL:The goal of this study was to determine the relative significance of douching as a risk factor for BV. STUDY DESIGN:Two hundred fifty adolescent women who regularly douched were en...
journal_title:Sexually transmitted diseases
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/01.olq.0000129948.91055.9f
更新日期:2004-07-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to describe acceptability of urine chlamydia testing among asymptomatic men and providers' attitudes toward testing. STUDY DESIGN:Asymptomatic men (no urethral discharge/dysuria) were offered free testing and characteristics of men who accepted were compared with those who dec...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,多中心研究
doi:10.1097/01.olq.0000230438.12636.eb
更新日期:2007-03-01 00:00:00
abstract:BACKGROUND:HerpeSelect HSV-1 and HSV-2 ELISAs are glycoprotein G-based, type-specific antibody detection tests that are approved by the US Food and Drug Administration for diagnosis of genital herpes. GOAL:The goal was to determine seroconversion times by means of HerpeSelect ELISAs. STUDY DESIGN:Four-hundred thirtee...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200304000-00007
更新日期:2003-04-01 00:00:00
abstract::In a retrospective study, the prevalence of antibodies to Chlamydia trachomatis serovars D to K, C. pneumoniae, and C. psittaci in cases attending a genitourinary clinic was examined. Blood samples were collected from 7,002 cases attending the clinic in Doncaster, England between May 1983 and May 1990. Sera from these...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199303000-00001
更新日期:1993-03-01 00:00:00
abstract:BACKGROUND:Pelvic inflammatory disease (PID) is commonly diagnosed in US emergency departments (EDs). We aimed to estimate national rates of provider adherence to the Centers for Disease Control and Prevention (CDC) treatment guidelines for PID among patient visits, with a diagnosis of acute PID in US ED settings. MET...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e31820b8bb4
更新日期:2011-04-01 00:00:00