Abstract:
BACKGROUND:Oral human papillomavirus (HPV) and human herpesvirus-8 (HHV8) infections are sexually transmitted and respectively associated with the development of oropharyngeal carcinoma and Kaposi sarcoma. The aim of the study was to evaluate HPV prevalence and its possible correlation with HHV8 oral shedding, in relation to sex, human immunodeficiency virus (HIV) behavioral risk factor, and immune function. METHODS:The study population comprised 100 HIV-infected individuals divided into 3 groups: (1) 38 men who have sex with men (MSM), (2) 24 heterosexual men, and (3) 38 women. DNA was obtained from cells of unstimulated whole saliva. Human papillomavirus sequences were searched for by polymerase chain reaction (PCR) with MY09/MY11 primers or by nested PCR with GP5+/GP6+ primers as the second step. Typing was accomplished by restriction fragment length polymorphism analysis or by direct sequencing or by reverse line blot. Human herpesvirus-8 sequences were detected and quantified by nested PCR and real-time PCR, respectively. RESULTS:Oral HPV infection was present in 37 (prevalence, 37%) of 100 (13 with high-risk and 24 with low-risk types) patients; the most frequent types were HPV16, HPV6, HPV10, HPV61, HPV66, and HPV83. Human herpesvirus-8 DNA was detected in 46 (46%) of 100 subjects. Both infections had the highest prevalence among MSM and the lowest among women; women had a lower prevalence of high-risk HPV types than did both male groups (P = 0.05). An inverse correlation was observed with concomitant oral HHV8 infection (P = 0.007). CONCLUSIONS:High prevalence of oral HPV and HHV8 infections was observed; MSM had the highest figures, despite better control of HIV infection.
journal_name
Sex Transm Disjournal_title
Sexually transmitted diseasesauthors
Del Mistro A,Baboci L,Frayle-Salamanca H,Trevisan R,Bergamo E,Lignitto L,Sasset L,Cecchetto MG,Cattelan AM,Calabró MLdoi
10.1097/OLQ.0b013e31826ef2dasubject
Has Abstractpub_date
2012-11-01 00:00:00pages
894-8issue
11eissn
0148-5717issn
1537-4521pii
00007435-201211000-00012journal_volume
39pub_type
杂志文章abstract:BACKGROUND:Clinical studies demonstrate increased prevalence of human papillomavirus (HPV)-associated disease in HIV-infected individuals and an increased risk of HIV acquisition in HPV-infected individuals. The mechanisms underlying this synergy are not defined. We hypothesize that women with cervical intraepithelial ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e318255aeef
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Persistence of syphilis in communities may be maintained by relatively small groups of high-risk persons centrally placed among a larger group with low to moderately risky behavior. We sought to determine which control strategies identified particularly high-risk, early-stage syphilis cases consid...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000216063.75575.f8
更新日期:2006-10-01 00:00:00
abstract::Pelvic inflammatory disease (PID), one of the major sequelae of the current epidemic of sexually transmitted diseases, has been shown to be a polymicrobial infection. This study compares the efficacy and safety of two broad-spectrum combination drug regimens, cefotetan with doxycycline and cefoxitin with doxycycline, ...
journal_title:Sexually transmitted diseases
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00007435-199118020-00012
更新日期:1991-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The past 10 years' wave of syphilis epidemics has challenged syphilis control programs. Although apparently connected to drugs-for-sex trading of crack cocaine, the genesis and resolution of these epidemics is poorly understood. GOALS OF THE STUDY:The goals of this study were to develop a mat...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199601000-00008
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:Herpes simplex virus (HSV) infection is one of the most common viral infections worldwide. Genital herpes is associated with other sexually transmitted infections (STIs) including HIV. Data on prevalence of HSV infections and other STIs in the Kingdom of Saudi Arabia are limited. METHODS:We conducted the fi...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000336
更新日期:2015-09-01 00:00:00
abstract::To define the performance characteristics of two newer tests for Trichomonas vaginalis (TV), the authors compared direct fluorescent antibody (DFA) (mixed monoclonal antibody, Integrated Diagnostics, Inc, Berkeley, CA) and acridine orange (AO) tests to standard wet mount (WM) preparations and culture (modified Diamond...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198907000-00002
更新日期:1989-07-01 00:00:00
abstract:BACKGROUND:Few studies have examined the association between self-reported sexual risk behaviors and biologic outcomes in human immunodeficiency virus (HIV)-1-seropositive African adults. METHODS:We conducted a prospective cohort study in 898 HIV-1-seropositive women who reported engaging in transactional sex in Momba...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e31820369f6
更新日期:2011-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The Cuban Ministry of Public Health plans to implement the syndromic approach to sexually transmitted diseases in persons with urethral or vaginal syndrome in Cuba using 500 mg ciprofloxacin as therapy. Although the emergence of clinical isolates of Neisseria gonorrhoeae with decreased suscept...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200102000-00004
更新日期:2001-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:More than 30 different human papillomavirus (HPV) types infect the anogenital mucosa and are responsible for a variety of benign, premalignant, and malignant lesions including cervical cancer. The goal of this study was to determine the distribution of individual HPV types in various grads of ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199709000-00005
更新日期:1997-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The care of patients with first episode and recurrent genital herpes differs with respect to therapy and source partner evaluation. Of 498 persons who presented with what appeared by history and symptoms to be a first episode of genital herpes, we identified 41 who had serologic evidence of re...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199904000-00007
更新日期:1999-04-01 00:00:00
abstract:BACKGROUND:The epidemiology of sexually transmitted infections (STIs) and HIV in Vanuatu is poorly defined. GOAL:The goal was to determine the prevalence of laboratory-confirmed gonorrhea, chlamydia, trichomoniasis, syphilis seroreactivity, and HIV among pregnant women in Vila, Vanuatu. STUDY DESIGN:A cross-sectional...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200304000-00017
更新日期:2003-04-01 00:00:00
abstract:BACKGROUND:Millions of cases of sexually transmitted infections (STIs) occur in the United States each year, resulting in substantial medical costs to the nation. Previous estimates of the total direct cost of STIs are quite dated. We present updated direct medical cost estimates of STIs in the United States. METHODS:...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e318285c6d2
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Few studies have demonstrated that bacterial vaginosis (BV) is associated with sexual behavior risk factors similar to those for other sexually transmitted diseases. The objective of this study was to determine the prevalence of these factors in a multivariate analysis of data from women infec...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199705000-00001
更新日期:1997-05-01 00:00:00
abstract:OBJECTIVES:To determine whether women who collect self-collected vaginal swabs at home demonstrated a higher positivity of Chlamydia trachomatis than women in family planning clinics. METHODS:Collection kits for vaginal swabs were internet requested, collected at home, and mailed to a laboratory for testing; questionn...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e3182039d7f
更新日期:2011-02-01 00:00:00
abstract::The presence of serum IgG antibody to Mycoplasma hominis was studied by enzyme immunoassay in 150 women with suspected cervicitis at a clinic for sexually transmitted diseases. Positive levels of antibody were associated with gravidity and parity but not with age, method of birth control, or sexual behavior. Women fro...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:
更新日期:1983-10-01 00:00:00
abstract::Strains of Neisseria gonorrhoeae requiring arginine, hypoxanthine, and uracil (AHU) may cause disseminated gonococcal infection (DGI). A significant epidemiologic association was noted between the incidence of disseminated gonococcal infection and the presence of gonococci of the AHU auxotype in the community over a n...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198404000-00003
更新日期:1984-04-01 00:00:00
abstract:BACKGROUND:Different models of sexually transmitted infections (STIs) can yield substantially different conclusions about STI epidemiology, and it is important to understand how and why models differ. Frequency-dependent models make the simplifying assumption that STI incidence is proportional to STI prevalence in the ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000412
更新日期:2016-03-01 00:00:00
abstract:GOAL:To investigate the in vitro antimicrobial susceptibility of Neisseria gonorrhoeae strains isolated in 2004 and 2005 in Bangui, Central African Republic; Yaoundé, Cameroon; Antananarivo, Madagascar; and Ho Chi Minh Ville and Nha Trang, Vietnam. STUDY DESIGN:Antimicrobial susceptibility testing was performed by bot...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e31818318d8
更新日期:2008-11-01 00:00:00
abstract::The purpose of this study was to explore the benefit of high-dose intravaginal metronidazole as a maintenance therapy in reducing recurrence rates of bacterial vaginosis (BV). Eighteen women with a history of recurrent BV and symptomatic BV were treated with metronidazole 750 mg suppository intravaginally daily for 7 ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000123
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND:Hepatitis C virus (HCV) is a major global problem, transmitted primarily by percutaneous exposure to contaminated blood. GOAL:The goal of the study was to determine the seroprevalence of and risk factors for HCV among patients attending two urban STD clinics in Alberta. STUDY DESIGN:Anonymous unlinked sero...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200301000-00008
更新日期:2003-01-01 00:00:00
abstract::We studied the incidence of gonorrhea, gonococcal recidivism and related factors in venereal disease clinic patients. A sample of 2029 records, which were selected randomly, were reviewed. Gonorrhea and gonococcal recidivism were more common in nonwhite patients, particularly in nonwhite men. Gonorrhea occurred more t...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-197704000-00001
更新日期:1977-04-01 00:00:00
abstract:BACKGROUND:Little is known about cytokine responses to syphilis infection in HIV-1-infected individuals. METHODS:We retrospectively identified patients with HIV-1 and Treponema pallidum coinfection. Plasma samples from before, during, and after coinfection were analyzed for interleukin (IL)-2, IL-4, IL-6, IL-8, IL-10,...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e318193ca26
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND:After reaching an all-time low in 2000, syphilis incidence in the United States has increased as the burden shifted from heterosexuals to men who have sex with men (MSM). Houston, Texas, experienced 2 outbreaks of syphilis during this transformation in trends. Further evaluation is necessary to determine if ...
journal_title:Sexually transmitted diseases
pub_type: 历史文章,杂志文章
doi:10.1097/OLQ.0000000000000488
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:Since 2003, outbreaks of lymphogranuloma venereum (LGV) with anorectal syndrome have been increasingly recognized in many Western countries. All of them have been classified as LGV serovar L2b, mainly occurring in human immunodeficiency virus (HIV)-infected men who have had sex with men (MSM). We describe a ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000459
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Methods of HIV and STD prevention, which can be controlled by the receptive partner, are a high priority for research and development. Studies on the safety of Nonoxynol-9 (N-9) on the vaginal mucosa have yielded conflicting results. No Phase I study has evaluated the effect of N-9 on the rect...
journal_title:Sexually transmitted diseases
pub_type: 临床试验,杂志文章
doi:10.1097/00007435-199911000-00005
更新日期:1999-11-01 00:00:00
abstract::We describe a case of acute urethritis caused by Neisseria meningitidis group B in a heterosexual man. The symptoms started five days after intercourse that included fellatio with a casual female partner. No other urethral pathogens could be isolated. After intramuscular administration of penicillin G, clinical signs ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198807000-00007
更新日期:1988-07-01 00:00:00
abstract::Clinical observations indicate that herpes simplex virus type 1 (HSV-1) is significantly less likely than herpes simplex virus type 2 (HSV-2) to establish latency in (or reactivate from) sacral ganglionic tissue. In an effort to identify viral functions associated with latency, we analyzed HSV-1 isolates from three pa...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198607000-00005
更新日期:1986-07-01 00:00:00
abstract:BACKGROUND:Data on ocular syphilis (OS) and its clinical presentation are currently insufficient. This study aimed to investigate the characteristics of a cohort with a high OS incidence at a university hospital in Germany, focusing on clinical presentation of OS. METHODS:This single-center cohort study retrospectivel...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000001329
更新日期:2020-11-04 00:00:00
abstract:BACKGROUND:Infectious syphilis has increased substantially over the past decade. Targeting limited public health resources toward subpopulations with multiple reinfections may have a large impact in reducing onward transmission within a community. METHODS:A chart review was conducted for individuals with 4 or more inf...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000995
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:There is a high level of coinfection with human immunodeficiency virus (HIV) among persons diagnosed with syphilis in the United States. Public health workers at state and local health departments help inform exposed partners to sexually transmitted disease (STD)/HIV infections to facilitate early testing an...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000001201
更新日期:2020-08-01 00:00:00