Abstract:
BACKGROUND:Millions of cases of sexually transmitted infections (STIs) occur in the United States each year, resulting in substantial medical costs to the nation. Previous estimates of the total direct cost of STIs are quite dated. We present updated direct medical cost estimates of STIs in the United States. METHODS:We assembled recent (i.e., 2002-2011) cost estimates to determine the lifetime cost per case of 8 major STIs (chlamydia, gonorrhea, hepatitis B virus, human immunodeficiency virus (HIV), human papillomavirus, genital herpes simplex virus type 2, trichomoniasis and syphilis). The total direct cost for each STI was computed as the product of the number of new or newly diagnosed cases in 2008 and the estimated discounted lifetime cost per case. All costs were adjusted to 2010 US dollars. RESULTS:Results indicated that the total lifetime direct medical cost of the 19.7 million cases of STIs that occurred among persons of all ages in 2008 in the United States was $15.6 (range, $11.0-$20.6) billion. Total costs were as follows: chlamydia ($516.7 [$258.3-$775.0] million), gonorrhea ($162.1 [$81.1-$243.2] million), hepatitis B virus ($50.7 [$41.3-$55.6] million), HIV ($12.6 [$9.5-$15.7] billion), human papillomavirus ($1.7 [$0.8-$2.9] billion), herpes simplex virus type 2 ($540.7 [$270.3-$811.0] million), syphilis ($39.3 [$19.6-$58.9] million), and trichomoniasis ($24.0 [$12.0-$36.0] million). Costs associated with HIV infection accounted for more than 81% of the total cost. Among the nonviral STIs, chlamydia was the most costly infection. CONCLUSIONS:Sexually transmitted infections continue to impose a substantial cost burden on the payers of medical care in the United States. The burden of STIs would be even greater in the absence of STI prevention and control efforts.
journal_name
Sex Transm Disjournal_title
Sexually transmitted diseasesauthors
Owusu-Edusei K Jr,Chesson HW,Gift TL,Tao G,Mahajan R,Ocfemia MC,Kent CKdoi
10.1097/OLQ.0b013e318285c6d2subject
Has Abstractpub_date
2013-03-01 00:00:00pages
197-201issue
3eissn
0148-5717issn
1537-4521pii
00007435-201303000-00003journal_volume
40pub_type
杂志文章abstract:BACKGROUND AND OBJECTIVES:In the January-February, 1995 issue of Sexually Transmitted Diseases, Zenilman and colleagues reported a null association between incident sexually transmitted diseases (STDs) and self-reported condom use. That anomalous finding generated a flurry of letters to the editor, some of which were q...
journal_title:Sexually transmitted diseases
pub_type: 评论,杂志文章
doi:10.1097/00007435-199710000-00005
更新日期:1997-10-01 00:00:00
abstract:BACKGROUND:Serosorting, selecting sex partners of the same HIV status, may be associated with increased risk of sexually transmitted infection (STI). We examined the association between unprotected anal intercourse (UAI) with a seroconcordant partner and STIs among HIV-negative men who have sex with men (MSM) at an urb...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e31826e870d
更新日期:2012-12-01 00:00:00
abstract::Though ampicillin is no longer recommended as first-line therapy for infections caused by Neisseria gonorrhoeae, the cost and efficacy of this policy in low prevalence areas has not been investigated. The problem was highlighted by an outbreak of penicillin-resistant N. gonorrhoeae in an area where the proportion of r...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199010000-00005
更新日期:1990-10-01 00:00:00
abstract::A simple procedure that permits the rapid identification of clinical isolates of herpes simplex virus (HSV, type 1 or type 2) on the basis of stable and type-specific differences in the EcoRI restriction endonuclease patterns of the HSV-1 and HSV-2 genomes was tested for reliability. Complete concordance was first obt...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198404000-00007
更新日期:1984-04-01 00:00:00
abstract:BACKGROUND:The use of new technologies, such as mobile phones and internet, has increased dramatically in recent years. Text messages offer a novel method of sexual health promotion to young people who are the greatest users of new technology and are also at high risk of sexually transmitted infections (STIs). METHODS...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e3181f68d7b
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:Human immunodeficiency virus (HIV) and sexually transmitted infections (STI) are prevalent among men who have sex with men (MSM). GOAL:To estimate the prevalence of HIV and STIs in this group. STUDY:A total of 694 MSM were tested for HIV, hepatitis B (HBV), hepatitis C (HCV), human T-cell lymphotropic (HTL...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000194578.06795.2d
更新日期:2006-05-01 00:00:00
abstract::The base-line prevalence of human papillomavirus (HPV) infection among applicants for first trimester induced abortion and among a sexually transmitted disease (STD) clinic population with macroscopically visible condyloma is investigated. Cervical cells were collected from 505 women applying for induced abortion. Cel...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:
更新日期:1992-05-01 00:00:00
abstract:BACKGROUND:After reaching an all-time low in 2000, syphilis incidence in the United States has increased as the burden shifted from heterosexuals to men who have sex with men (MSM). Houston, Texas, experienced 2 outbreaks of syphilis during this transformation in trends. Further evaluation is necessary to determine if ...
journal_title:Sexually transmitted diseases
pub_type: 历史文章,杂志文章
doi:10.1097/OLQ.0000000000000488
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Patients with sexually transmitted diseases (STDs) are at an increased risk of HIV infection and they must be targeted for increased condom use. GOAL:To identify predictors of condom use among patients with STDs. STUDY DESIGN:In a cross-sectional survey, an interview-administered questionnair...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199910000-00001
更新日期:1999-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The Syva Micro Trak enzyme immunoassay (EIA) is used widely for screening women infected with Chlamydia trachomatis. Confirmatory tests used in conjunction with EIA screening have shown that false-positive results are common. GOALS:To evaluate the specificity of the Syva MicroTrak EIA by conf...
journal_title:Sexually transmitted diseases
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00007435-199611000-00005
更新日期:1996-11-01 00:00:00
abstract::We developed 4 algorithms for syphilis among HIV-positive men who have sex with men who engaged in primary care in 2016 to 2017. Clinician-based diagnosis from chart reviews was the gold standard. Sensitivities ranged from 74.2% to 93.9%. Specificities were greater than 99% with positive and negative predictive values...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000938
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:The effectiveness of counseling messages to avoid unprotected sex during short-term treatment for curable sexually transmitted infections is unknown. METHODS:We randomized 300 female STI clinic patients 18 years or older with cervicitis and/or vaginal discharge in Kingston, Jamaica, in 2010 to 2011, to 1 of...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/OLQ.0b013e31827938a1
更新日期:2013-02-01 00:00:00
abstract::Medical record review was used to identify missed opportunities for chlamydia screening among 103 American Indian/Alaska Native women. Of these, 69% had received a pregnancy test and 74% had received a urine test in the previous 12 months. Chlamydia screening may increase if linked to the other routine clinical testin...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e318222f126
更新日期:2011-10-01 00:00:00
abstract::Despite over a century of clinical experience in diagnosing and managing patients with syphilis, many thorny clinical questions remain unanswered. We focus on several areas of uncertainty for the clinician: the role of serologic tests in diagnosing syphilis and assessing syphilis treatment responses, and the risk of n...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,评审
doi:10.1097/OLQ.0000000000000851
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:The prevalence of gonorrhea (GC) among adolescent and young women attending some urban emergency departments (EDs) ranges from 1% to 7%, but historically screening has not been logistically practical. GOAL:The primary goal of the study was to assess the cost effectiveness of GC screening in women ages 15 to...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000154501.22566.fa
更新日期:2005-07-01 00:00:00
abstract::Among 413 Nigerian men who have sex with men and transgender women, retrospective testing for Mycoplasma genitalium revealed mostly asymptomatic infections of the anorectum (prevalence, 36.8%; incidence, 18.4 cases/100 person-years) and urogenital tract (12.4%, 4.0 cases/100 person-years). Risk factors included HIV an...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000001105
更新日期:2020-03-01 00:00:00
abstract::The objective of this study was to develop and apply a serologic method for identification of different strains of Neisseria gonorrhoeae. Several procedures for preparation of cell-free extracts were tried; the most satisfactory was that with phosphate-buffered saline solution. Both capillary tube and immunodiffusion ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198004000-00002
更新日期:1980-04-01 00:00:00
abstract::The dihydrofolate reductases were purified from Neisseria gonorrhoeae strains CDC 9 and 7134, for which MICs of trimethoprim differ twofold and MICs of sulfadiazine differ sixtyfold. Although affinities of the dihydropteroate synthetases from the two strains for sulfonamide were known to differ markedly, no conclusive...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-197804000-00002
更新日期:1978-04-01 00:00:00
abstract:OBJECTIVES:We addressed gaps in current HIV prevention research by examining the differences between 2 groups of young men: men who have sex with men only (MSM/O) and men who have sex with men and women (MSM/W). We examined patterns and correlates of sexual risk, and considered how race/ethnicity may affect these relat...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e3181924201
更新日期:2009-05-01 00:00:00
abstract:GOAL:To investigate the in vitro antimicrobial susceptibility of Neisseria gonorrhoeae strains isolated in 2004 and 2005 in Bangui, Central African Republic; Yaoundé, Cameroon; Antananarivo, Madagascar; and Ho Chi Minh Ville and Nha Trang, Vietnam. STUDY DESIGN:Antimicrobial susceptibility testing was performed by bot...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e31818318d8
更新日期:2008-11-01 00:00:00
abstract:BACKGROUND:Sexual partnerships between people at higher and lower risk for sexually transmitted infections (STIs) (i.e., bridging) occur through dissortative mixing and concurrent partnerships, yet the relative effects of these network patterns on population STI spread are poorly understood. GOAL:Using a stochastic mo...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000194586.66409.7a
更新日期:2006-06-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The goal of this study was to examine the relationship between contraceptive method choice and perceptions of HIV and pregnancy risk among women at risk of HIV infection and transmission. STUDY DESIGN:Women who were infected with HIV or who were at high risk of infection were administered a q...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199401000-00002
更新日期:1994-01-01 00:00:00
abstract::We described sexual transmission behaviors and serodiscordant partnerships among an online sample of HIV-positive men who have sex with men (N = 416) in Asia. High rates of unprotected anal intercourse (74.8%), serodiscordant partnerships (68.5%), and unprotected sex within serodiscordant partnerships (∼60.0%) were re...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e31824018e8
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:Studies of alcohol use and sexual behavior in African populations have primarily been cross-sectional, used nonvalidated measures of alcohol use, or relied on self-reported sexual risk endpoints. Few have focused on human immunodeficiency virus (HIV)-positive women. METHODS:Longitudinal data were collected ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000502
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:In resource-poor settings, control of Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT) among female sex workers (FSWs) is difficult. We sought to determine whether periodical antibiotic treatment (PAT) might be effective in controlling these infections among West African FSWs. Secondary objectives w...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,随机对照试验
doi:10.1097/OLQ.0b013e318244aaa0
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:To study the incidence, persistence, and determinants of human papillomavirus (HPV) infection in a population of Inuit women from Nunavik, Quebec, by overall HPV infection, Alphapapillomavirus (α) species, and oncogenic risk grouping. METHODS:We recruited a cohort of Inuit women living in communities in Nun...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000272
更新日期:2015-05-01 00:00:00
abstract::Ureaplasma urealyticum strains isolated from urethral specimens of 112 patients with nongonococcal urethritis, 17 with gonorrhea, and 33 asymptomatic carriers (controls) were tested by the growth-inhibition test with standard ureaplasma antisera (serotypes 1-8). Cases with more than one serotype (two to four types) we...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198510000-00010
更新日期:1985-10-01 00:00:00
abstract::The risk of tubal pregnancy associated with seropositivity to Chlamydia trachomatis or following a diagnosis of gonorrhea, genital herpes, trichomoniasis, genital warts, or nonspecific vaginal infection was evaluated in a study of this condition among women who were members of a prepaid health plan. A total of 264 wom...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199007000-00001
更新日期:1990-07-01 00:00:00
abstract:BACKGROUND:Higher gender equality is associated with many human immunodeficiency virus (HIV) preventive behaviors, including HIV testing. HIV self-testing is a relatively new testing technology that could assist with HIV prevention. However, there are no studies examining gender equality and HIV self-testing. We examin...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,随机对照试验
doi:10.1097/OLQ.0000000000001037
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVES:This study examined serologic markers of hepatitis B virus (HBV) infection and immunity among young Asian/Pacific Islander men who have sex with men (API MSM) in San Francisco. METHODS:Participants were 496 API MSM, aged 18 to 29 years, recruited to participate in a cross-sectional survey using a random, ve...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000148296.93945.53
更新日期:2005-01-01 00:00:00