Abstract:
:Despite over a century of clinical experience in diagnosing and managing patients with syphilis, many thorny clinical questions remain unanswered. We focus on several areas of uncertainty for the clinician: the role of serologic tests in diagnosing syphilis and assessing syphilis treatment responses, and the risk of neurosyphilis and ocular syphilis in patients with syphilis. We also address whether clinical approaches should differ in patients who are, and are not, infected with HIV. The current increases in syphilis rates in the United States and elsewhere underscore our urgent need to definitively address these issues.
journal_name
Sex Transm Disjournal_title
Sexually transmitted diseasesauthors
Marra CM,Ghanem KGdoi
10.1097/OLQ.0000000000000851subject
Has Abstractpub_date
2018-09-01 00:00:00pages
S10-S12issue
9S Suppl 1eissn
0148-5717issn
1537-4521pii
00007435-201809001-00003journal_volume
45pub_type
杂志文章,评审abstract::Performance characteristics of the Cobas 4800 CT/NG assay were estimated for vaginal swab samples from more than 4000 women. Vaginal samples identified 92.9% and 98.5% of Chlamydia and Gonorrhea infections, respectively, which was more than any other single specimen type (endocervical swabs or urine) regardless of col...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/OLQ.0b013e3182717833
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:Measurement of human immunodeficiency virus(HIV) incidence among female sex workers in Rwanda is a key part of preparing for HIV prevention trials. METHODS:HIV-negative, nonpregnant female sex workers (N =397) were tested for HIV-1, sexually transmitted infections, and pregnancy quarterly for 12 months, and...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/olq.0b013e31820b8eba
更新日期:2011-05-01 00:00:00
abstract:BACKGROUND:Calls for increased investment in sexually transmitted infection (STI) treatment across the developing world have been made to address the high disease burden and the association with HIV transmission. GOALS:The goals of this study were to systematically review evidence on the cost of treating curable STIs ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,评审
doi:10.1097/01.olq.0000235177.30718.84
更新日期:2006-10-01 00:00:00
abstract::We analyzed prevalence rates of syphilis (positive Treponema pallidum hemagglutinin antigen/T. pallidum particle antigen and venereal disease research laboratory test) among police officers in Guinea-Bissau from 1990 to 2010 and found a significant decline from 4.5% to 0.4% (P = 0.0065). Our results are in line with o...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000012
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:Evaluating chlamydia prevalence trends from sentinel surveillance is important for understanding population disease burden over time. However, prevalence trend estimates from surveillance data may be misleading if they do not account for changes in risk profiles of individuals who are screened (case mix) and...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000798
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Up to 50% of women with nonoptimal vaginal microbial community state type (CST) have bacterial vaginosis (BV). Little is known about what distinguishes women with and without BV diagnosis within nonoptimal CST. We identified features of women and their male sex partners associated with BV among women with no...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000001259
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:To obtain patients' perspectives on why only some partners are notified in partner-notification programs, the cornerstone of sexually transmitted disease (STD) control, although low proportions of partners are located and evaluated. GOALS:To describe patterns of partner notification reported ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200004000-00003
更新日期:2000-04-01 00:00:00
abstract:BACKGROUND:Methods for accessing large sexual networks are essential for investigating the mechanisms for the spread of sexually transmitted infections. GOAL:Four samples of cases were compared with the total population to determine which identified the largest networks. STUDY DESIGN:Individuals with positive test re...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200104000-00003
更新日期:2001-04-01 00:00:00
abstract:BACKGROUND:Human immunodeficiency virus (HIV)/sexually transmitted disease (STD)-related interventions rely on self-reported risk behavioral data, which are biased toward social desirability. It is warranted to develop methods for data triangulation. METHODS:Some questions on HIV/STD-related behaviors that were asked ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e318218cc66
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:Oral human papillomavirus (HPV) and human herpesvirus-8 (HHV8) infections are sexually transmitted and respectively associated with the development of oropharyngeal carcinoma and Kaposi sarcoma. The aim of the study was to evaluate HPV prevalence and its possible correlation with HHV8 oral shedding, in relat...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e31826ef2da
更新日期:2012-11-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to determine levels of experience and knowledge concerning anal dysplasia, anal Pap smear tests, and human papillomavirus (HPV) among gay and other homosexually active men. STUDY DESIGN:Three hundred eighty-four men attending a large gay community event in Melbourne completed ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000230436.83029.ce
更新日期:2007-03-01 00:00:00
abstract:OBJECTIVES:To evaluate opportunities for earlier human immunodeficiency virus (HIV) diagnosis within a comprehensive public health care system. STUDY DESIGN:Retrospective review of newly diagnosed HIV-infected patients between September 2001 and December 2003. RESULTS:One hundred twenty of 348 (34%) newly diagnosed H...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000194617.91454.3f
更新日期:2006-05-01 00:00:00
abstract::In contrast to high rates of oral human papillomavirus (HPV) found in human immunodeficiency virus (HIV)-infected adults, only 2% of 209 perinatally HIV-infected youth had oral HPV. This rate was similar in HIV-exposed but uninfected youth. No association was found with sexual activity; however, low CD4 counts were as...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000495
更新日期:2016-08-01 00:00:00
abstract::Strains of Trichomonas vaginalis were evaluated for their in vitro responses to metronidazole. A serial twofold dilution method that measured minimal inhibitory concentrations (MICs) by cessation of trophozoite motility was compared with the disk broth method, in which both cessation of motility and inhibition of trop...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198007000-00005
更新日期:1980-07-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to determine herpes simplex virus type 2 (HSV-2) seroprevalence at HIV-1 diagnosis and seroincidence > or =1 year after HIV-1 diagnosis. METHODS:HSV type-specific antibodies were detected by enzyme immunoassay. RESULTS:The cohort comprised 850 adults diagnosed HIV-positive in...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000187211.61052.c7
更新日期:2006-02-01 00:00:00
abstract:BACKGROUND:Despite antiretroviral therapy (ART), incident human immunodeficiency virus (HIV) continues to rise, and sexually transmitted infections (STI) are well known for their part in HIV transmission. National guidelines recommend routine STI screening in HIV-positive individuals, but despite this, reported uptake ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e31822e6136
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:Different models of sexually transmitted infections (STIs) can yield substantially different conclusions about STI epidemiology, and it is important to understand how and why models differ. Frequency-dependent models make the simplifying assumption that STI incidence is proportional to STI prevalence in the ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000412
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND:Sexual behaviors have been linked to seropositivity for human papillomavirus (HPV) but not with the magnitude of the seroreactivity. GOALS:The objective of this analysis was to examine the association of sexual behavior, cervical HPV 16 DNA positivity at enrollment (past) and at diagnosis (current), and oth...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200203000-00009
更新日期:2002-03-01 00:00:00
abstract:BACKGROUND:Identifying and treating genital infections, including sexually transmitted infections (STI), among newly diagnosed human immunodeficiency virus (HIV)-infected individuals may benefit both public and individual health. We assessed prevalence of genital infections and their correlates among newly diagnosed HI...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000513
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:Risk factors for bacterial vaginosis (BV) include douching and sexual activity, although the exact cause of BV is unknown. GOAL:The goal of this study was to determine the relative significance of douching as a risk factor for BV. STUDY DESIGN:Two hundred fifty adolescent women who regularly douched were en...
journal_title:Sexually transmitted diseases
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/01.olq.0000129948.91055.9f
更新日期:2004-07-01 00:00:00
abstract:OBJECTIVES:To examine the epidemiology of multiple infections in teenagers and their contacts. GOAL:To demonstrate a network approach to the prevalence of STDs/HIV. STUDY DESIGN:A community-based network study of ethnographically representative adolescents. RESULTS:Of the 512 interviewees, 90% of the boys and 80% of...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000258132.06764.a1
更新日期:2007-08-01 00:00:00
abstract:OBJECTIVE:Detection of vaginal Y-chromosome sequences (YCS) may be a useful biomarker to validate sexual behavior reporting in women. We describe the effects of condom use on the detection of vaginal YCS. METHODS:Fifty-six women were asked to abstain from sexual intercourse for 14 days. On day 15, participants were as...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000258318.99606.d9
更新日期:2007-08-01 00:00:00
abstract:BACKGROUND:The Centers for Disease Control and Prevention recommends annual sexually transmitted infection (STI) and HIV testing and counseling for men who have sex with men (MSM) in the United States. We estimated the annual total direct medical cost of providing recommended STI and HIV testing and counseling services...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000341
更新日期:2015-10-01 00:00:00
abstract::Improved technologies for the cultural diagnosis of chancroid have resulted in increased interest in the management and control of genital ulcer disease. New treatment regimens have been identified, and new control strategies have evolved. These strategies now permit localized introductions of chancroid into developed...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,评审
doi:10.1097/00007435-198607000-00019
更新日期:1986-07-01 00:00:00
abstract::Partner notification for HIV and other sexually transmitted infections is acceptable and feasible among female sex workers attending sexually transmitted infection clinics in Guatemala, especially for regular partners. Intention to refer the sexual partner was best predicted by attitude followed by social norms and ba...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e31824f8b1b
更新日期:2012-07-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to provide updated estimates of the average lifetime medical cost per infection for chlamydia, gonorrhea, and trichomoniasis. METHODS:We adapted a published decision tree model that allowed for 7 possible outcomes of infection: (1) symptomatic infection, treated, no sequelae; (...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000001357
更新日期:2021-01-23 00:00:00
abstract::A system was developed for the collection, coding, and processing of data from routine reports describing morbidity caused by gonorrhea. These data are coded centrally, and tables that provide information about the age, sex, race, source of care, and geographic and temporal distributions of the population affected by ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-197901000-00002
更新日期:1979-01-01 00:00:00
abstract:BACKGROUND:High incidence and prevalence of sexually transmitted infection (STI) in blacks have been attributed to multiple factors. However, few articles have discussed spatial access to healthcare as a driver of disparities. The objective of this analysis was to evaluate the relationship between travel time to a heal...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e318235b673
更新日期:2012-02-01 00:00:00
abstract::Verification of relationship status beyond self-report is an important aspect in sexually transmitted infection research, including partner treatment studies where primary sexual partners are targeted for enrollment. This exploratory study describes the use of a novel couples' verification tool in a male partner treat...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000001225
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVES:To investigate, among male injecting drug users (IDU), the relationships between higher risk IDU-related and sex-related behaviors. GOAL:To highlight the clustering effects of the 2 forms of risk behaviors. STUDY DESIGN:Behavioral surveillance surveys conducted in Sichuan were analyzed (n = 3105). RESULTS...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000253339.49181.f9
更新日期:2007-08-01 00:00:00