The Estimated Lifetime Medical Cost of Chlamydia, Gonorrhea, and Trichomoniasis in the United States, 2018.

Abstract:

BACKGROUND:The purpose of this study was to provide updated estimates of the average lifetime medical cost per infection for chlamydia, gonorrhea, and trichomoniasis. METHODS:We adapted a published decision tree model that allowed for 7 possible outcomes of infection: (1) symptomatic infection, treated, no sequelae; (2) symptomatic infection, not treated, sequelae; (3) symptomatic infection, not treated, no sequelae; (4) asymptomatic infection, treated, sequelae; (5) asymptomatic infection, treated, no sequelae; (6) asymptomatic infection, not treated, sequelae; and (7) asymptomatic infection, not treated, no sequelae. The base case values and ranges we applied for the model inputs (i.e., the probability and cost assumptions) were based on published studies. RESULTS:The estimated lifetime medical cost per infection for men and women, respectively, was $46 (95% credibility interval: $32-62) and $262 ($127-483) for chlamydia, $78 ($36-145) and $254 ($96-518) for gonorrhea, and $5 ($1-14) and $36 ($17-58) for trichomoniasis. Cost estimates for men were most sensitive to assumptions regarding the probability that the infection is symptomatic, the probability of treatment if asymptomatic, and the cost of treatment of infection. Cost estimates for chlamydia and gonorrhea in women were most sensitive to assumptions regarding the probability and cost of subsequent pelvic inflammatory disease (PID). CONCLUSIONS:These estimates of the lifetime medical cost per infection can inform updated estimates of the total annual cost of sexually transmitted infections (STIs) in the United States, as well as analyses of the value and cost-effectiveness of STI prevention interventions.

journal_name

Sex Transm Dis

authors

Kumar S,Chesson H,Spicknall IH,Kreisel K,Gift TL

doi

10.1097/OLQ.0000000000001357

subject

Has Abstract

pub_date

2021-01-23 00:00:00

eissn

0148-5717

issn

1537-4521

pii

00007435-900000000-97759

pub_type

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