Zenilman's anomaly reconsidered: fallible reports, ceteris paribus, and other hypotheses.

Abstract:

BACKGROUND AND OBJECTIVES:In the January-February, 1995 issue of Sexually Transmitted Diseases, Zenilman and colleagues reported a null association between incident sexually transmitted diseases (STDs) and self-reported condom use. That anomalous finding generated a flurry of letters to the editor, some of which were quite heated. This article reconsiders the Zenilman team's results. STUDY DESIGN:New statistical analyses were conducted to test two hypotheses that sought to account for the null association: (1) deviation from study protocol, and (2) differential risks of acquiring an incident STD among segments of the study population that varied by reported level of condom use. RESULTS:No support was found for hypotheses concerning deviation from study protocol and differential risk of acquiring an incident STD by level of condom use. Indeed, for respondents who reported multiple sexual partners, the analyses found increased rates of infection among those who reported more consistent condom use. CONCLUSIONS:Two of the most promising hypotheses for explaining Zenilman's anomalous findings are unsupported by reanalysis of the available empirical evidence. It is still possible that respondents who reported that they used condoms consistently differed from self-reported nonusers or inconsistent users in some way that altered their risk of acquiring an STD and thus obscured the protective effects of properly used condoms. Nonetheless, as Zenilman and others suggest, fallibility in self-reports of condom use remains the primary suspect as the cause of these anomalous results. Such fallibility may be particularly pronounced when self-reported behavioral data are collected in contexts that include strong educational campaigns or other norm-setting interventions.

journal_name

Sex Transm Dis

authors

Turner CF,Miller HG

doi

10.1097/00007435-199710000-00005

subject

Has Abstract

pub_date

1997-10-01 00:00:00

pages

522-7

issue

9

eissn

0148-5717

issn

1537-4521

journal_volume

24

pub_type

评论,杂志文章
  • Bacterial vaginosis among African American women who have sex with women.

    abstract:BACKGROUND:Bacterial vaginosis (BV) is a frequent cause of vaginal discharge that may be more common among women reporting sex with women (WSW). The objective of this study was to determine the prevalence of BV and predictors of infection among a sample of African American WSW. METHODS:African American WSW aged 18 yea...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0000000000000004

    authors: Muzny CA,Sunesara IR,Austin EL,Mena LA,Schwebke JR

    更新日期:2013-09-01 00:00:00

  • Comparison of once-daily and twice-daily dosing of 0.75% metronidazole gel in the treatment of bacterial vaginosis.

    abstract:BACKGROUND AND OBJECTIVES:Bacterial vaginosis is the most common cause of vaginal symptoms in women and has potential complications. Efforts to improve treatment of this disease process are warranted. GOAL OF THIS STUDY:The goal of this study was to compare the safety and efficacy of once-daily intravaginal administra...

    journal_title:Sexually transmitted diseases

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1097/00007435-199903000-00003

    authors: Livengood CH 3rd,Soper DE,Sheehan KL,Fenner DE,Martens MG,Nelson AL,Ismail M,Thorp JM,Lappin M,Long BJ,Blackwelder T,Sweet RL,Sagov S

    更新日期:1999-03-01 00:00:00

  • Azithromycin treatment failure among primary and secondary syphilis patients in Shanghai.

    abstract:BACKGROUND:Azithromycin has been used to treat primary and secondary syphilis and as prophylaxis for sexual partners. We evaluated syphilis treatment failure in patients who received azithromycin therapy. METHODS:Patients who did not respond to azithromycin therapy were referred to Shanghai Skin Disease and sexually t...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e3181e2c753

    authors: Zhou P,Li K,Lu H,Qian Y,Gu X,Gong W,Tucker JD,Cohen MS

    更新日期:2010-11-01 00:00:00

  • Efficacy of a booster counseling session 6 months after HIV testing and counseling: a randomized, controlled trial (RESPECT-2).

    abstract:BACKGROUND:HIV counseling prevents sexually transmitted diseases (STDs), with most of the benefit accumulating in the first 6 months. STUDY:The authors conducted a multicenter, randomized, controlled trial of a 20-minute additional (booster) counseling session 6 months after HIV counseling compared with no additional ...

    journal_title:Sexually transmitted diseases

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1097/01.olq.0000151420.92624.c0

    authors: Metcalf CA,Malotte CK,Douglas JM Jr,Paul SM,Dillon BA,Cross H,Brookes LC,Deaugustine N,Lindsey CA,Byers RH,Peterman TA,RESPECT-2 Study Group.

    更新日期:2005-02-01 00:00:00

  • Prevalence of Anal Dysplasia in Human Immunodeficiency Virus-Infected Transgender Women.

    abstract::Although human immunodeficiency virus-infected men who have sex with men are at high risk for anal cancer, little is known about the prevalence of anal dysplasia in human immunodeficiency virus (HIV)-infected transgender women. Our study found that prevalence rates of abnormal anal cytology and histology in HIV-infect...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0000000000000673

    authors: Kobayashi T,Sigel K,Gaisa M

    更新日期:2017-11-01 00:00:00

  • Identifying likely syphilis transmitters: implications for control and evaluation.

    abstract:BACKGROUND/OBJECTIVES:Persistence of syphilis in communities may be maintained by relatively small groups of high-risk persons centrally placed among a larger group with low to moderately risky behavior. We sought to determine which control strategies identified particularly high-risk, early-stage syphilis cases consid...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/01.olq.0000216063.75575.f8

    authors: Kahn RH,Peterman TA,Arno J,Coursey EJ,Berman SM

    更新日期:2006-10-01 00:00:00

  • Relationship Gender Equality and Couples' Uptake of Oral Human Immunodeficiency Virus Self-Testing Kits Delivered by Pregnant Women in Kenya.

    abstract:BACKGROUND:Higher gender equality is associated with many human immunodeficiency virus (HIV) preventive behaviors, including HIV testing. HIV self-testing is a relatively new testing technology that could assist with HIV prevention. However, there are no studies examining gender equality and HIV self-testing. We examin...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/OLQ.0000000000001037

    authors: Vrana-Diaz CJ,Korte JE,Gebregziabher M,Richey L,Selassie A,Sweat M,Gichangi A

    更新日期:2019-09-01 00:00:00

  • Effect of multiple freeze and thaw cycles on the sensitivity of IgG and IgM immunoglobulins in the sera of patients with syphilis.

    abstract::We describe the effects of multiple freeze and thaw cycles on the sensitivity of the immunoglobulins IgG and IgM measured by enzyme-linked immunoassays in the sera of patients with syphilis. Stored frozen sera can withstand repeated freezing and thawing cycles with a minimal detrimental effect on the sensitivity of th...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0000000000000036

    authors: Castro AR,Jost HA

    更新日期:2013-11-01 00:00:00

  • Longitudinal examination of alcohol use: a predictor of risky sexual behavior and Trichomonas vaginalis among African-American female adolescents.

    abstract:BACKGROUND:Alcohol use has been linked to risky sexual practices among adolescents. However, limited research on alcohol use and risky sexual behavior has been conducted on African-American female adolescents. This study examined high quantity of alcohol as a longitudinal predictor of risky sexual behavior and sexually...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e3181f07abe

    authors: Seth P,Sales JM,DiClemente RJ,Wingood GM,Rose E,Patel SN

    更新日期:2011-02-01 00:00:00

  • HIV postexposure prophylaxis use among Ontario female adolescent sexual assault victims: a prospective analysis.

    abstract:BACKGROUND:This study examined the use of HIV postexposure prophylaxis (PEP) among sexually assaulted adolescent females. METHODS:We analyzed data from the HIV PEP Project, an implementation and evaluation of a program of universal offering of PEP to sexual assault victims of all ages. Baseline and follow-up data were...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e3181824f3c

    authors: Du Mont J,Myhr TL,Husson H,Macdonald S,Rachlis A,Loutfy MR

    更新日期:2008-12-01 00:00:00

  • Analytical specificity and sensitivity of the APTIMA Combo 2 and APTIMA GC assays for detection of commensal Neisseria species and Neisseria gonorrhoeae on the Gen-Probe Panther instrument.

    abstract::Genetic detection of Neisseria gonorrhoeae is replacing culture for increased diagnostic sensitivity. Specificity of several nucleic acid amplification tests is suboptimal. Herein, the Gen-Probe APTIMA Combo 2 and APTIMA GC assays had 100% specificity and 100% sensitivity after confirmatory testing, when testing 298 i...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e3182787e45

    authors: Golparian D,Tabrizi SN,Unemo M

    更新日期:2013-02-01 00:00:00

  • Prevalence and risk factors for human herpesvirus 8 infection in northern Cameroon.

    abstract:BACKGROUND:The modes of transmission of HHV-8 are still unclear. GOAL:To evaluate the distribution and transmission of HHV-8 infection. DESIGN:Serosurvey conducted in a Cameroon hospital among 292 persons, including children (5-10 years), adolescents (15-20 years), and adults (30-40 years). Antibodies against lytic a...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-200003000-00008

    authors: Rezza G,Tchangmena OB,Andreoni M,Bugarini R,Toma L,Bakary DK,Glikoutou M,Sarmati L,Monini P,Pezzotti P,Ensoli B

    更新日期:2000-03-01 00:00:00

  • Prevalence of human papillomavirus infection in Guangdong Province, China: a population-based survey of 78,355 women.

    abstract:BACKGROUND:The prevalence of human papillomavirus (HPV) infection and the distribution of different HPV genotypes vary greatly within different geographical and ethnic populations, especially in Asia. The HPV infection data based on regional population are extremely important for researchers to develop new efficient HP...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0000000000000201

    authors: Jing L,Zhong X,Zhong Z,Huang W,Liu Y,Yang G,Zhang X,Zou J,Jing C,Wei X

    更新日期:2014-12-01 00:00:00

  • Diagnosis of gonorrhea by gram-stained smears and cultures in men and women: role of the urethral smear.

    abstract::A retrospective study of the diagnosis of gonorrhea by gram-stained smear and culture was made. Of 1,681 men with gonococcal urethritis, 1,437 (85.5%) were positive by both smear and culture; 151 (9%), by smear alone; and 93 (5.5%), by culture alone. Of 1,148 women with gonorrhea, 742 (64.6%) had infection in both the...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-198507000-00008

    authors: Goh BT,Varia KB,Ayliffe PF,Lim FK

    更新日期:1985-07-01 00:00:00

  • Benefits and Potential Harms of Human Immunodeficiency Virus Self-Testing Among Men Who Have Sex With Men in China: An Implementation Perspective.

    abstract:BACKGROUND:Human immunodeficiency virus self-testing (HIVST) holds great promise for reaching high-risk key populations who do not access facility-based services. We sought to characterize unsupervised HIVST implementation among men who have sex with men in China. METHODS:We conducted a nationwide online survey in Chi...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0000000000000581

    authors: Qin Y,Tang W,Nowacki A,Mollan K,Reifeis SA,Hudgens MG,Wong NS,Li H,Tucker JD,Wei C

    更新日期:2017-04-01 00:00:00

  • Pregnancy, Penile-anal Sex, and Other Sexual Behaviors in the United States, 2011-2015.

    abstract::We used the US national survey data to examine sexual behavior by pregnancy status and found that, overall, pregnant women did not differ from nonpregnant women in penile-anal sex and associated condom use. Compared with nonpregnant women, pregnant women had lower or similar reports of other sexual behaviors. ...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0000000000000927

    authors: Leichliter JS,Aral SO

    更新日期:2019-03-01 00:00:00

  • Prenatal syphilis screening rates measured using medicaid claims and electronic medical records.

    abstract:BACKGROUND:To prevent congenital syphilis, the Centers for Disease Control and Prevention and professional organizations recommend universal prenatal syphilis screening. State-level or larger-scale evaluations of adherence to these guidelines have relied on administrative data. We measured prenatal syphilis screening r...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e31815fa5bb

    authors: Rosenman MB,Tao G,Szucs KA,Wang J,Ambuehl R,Mahon BE

    更新日期:2008-04-01 00:00:00

  • Colonization of sexually abused children with genital mycoplasmas.

    abstract::Although sexually abused children are usually evaluated only for the presence of infections with Neisseria gonorrhoeae and Treponema pallidum, they are also at risk for acquiring other sexually transmitted organisms prevalent in the adult population. Accordingly, we examined pharyngeal, anorectal and genital specimens...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-198701000-00005

    authors: Hammerschlag MR,Doraiswamy B,Cox P,Cummings M,McCormack WM

    更新日期:1987-01-01 00:00:00

  • Innovative resources could help improve partner notification for chlamydia in primary care.

    abstract:OBJECTIVE:To examine practices of general practitioners' (GPs) in relation to partner notification for chlamydia and identify the supports they would find most useful to assist them. GOAL:To identify innovative resources that could improve partner notification for chlamydia in primary care. STUDY DESIGN:A postal surv...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e3181b357f6

    authors: Bilardi JE,Hopkins CA,Fairley CK,Hocking JS,Tomnay JE,Pavlin NL,Parker RM,Temple-Smith MJ,Bowden FJ,Russell DB,Pitts M,Chen MY

    更新日期:2009-12-01 00:00:00

  • Acceptability of urine-based screening for Chlamydia trachomatis to asymptomatic young men and their providers.

    abstract:OBJECTIVE:The objective of this study was to describe acceptability of urine chlamydia testing among asymptomatic men and providers' attitudes toward testing. STUDY DESIGN:Asymptomatic men (no urethral discharge/dysuria) were offered free testing and characteristics of men who accepted were compared with those who dec...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章,多中心研究

    doi:10.1097/01.olq.0000230438.12636.eb

    authors: Marrazzo JM,Ellen JM,Kent C,Gaydos C,Chapin J,Dunne EF,Rietmeijer CA

    更新日期:2007-03-01 00:00:00

  • The estimated direct medical cost of selected sexually transmitted infections in the United States, 2008.

    abstract:BACKGROUND:Millions of cases of sexually transmitted infections (STIs) occur in the United States each year, resulting in substantial medical costs to the nation. Previous estimates of the total direct cost of STIs are quite dated. We present updated direct medical cost estimates of STIs in the United States. METHODS:...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e318285c6d2

    authors: Owusu-Edusei K Jr,Chesson HW,Gift TL,Tao G,Mahajan R,Ocfemia MC,Kent CK

    更新日期:2013-03-01 00:00:00

  • Lymphogranuloma venereum presenting as superclavicular and inguinal lymphadenopathy.

    abstract::A 46-year-old woman developed a febrile illness characterized by supraclavicular and inguinal lymphadopathy. The diagnosis of lymphogranuloma venereum was made by a fourfold rise in complement fixing antibody titer. Treatment with tetracycline was successful. Lymphogranuloma venereum can yield protean manifestations, ...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-197701000-00004

    authors: Walzer PD,Armstrong D

    更新日期:1977-01-01 00:00:00

  • Trends in sexual behavior. Analyse des Comportements Sexuels en France Investigators.

    abstract::The definition of strategies for preventing STD and AIDS requires a better knowledge of sexual behavior in the general population and in specific subgroups of the population. Surveys have been undertaken in different countries to provide such information, and they allow to draw some general conclusions. Even if there ...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章,评审

    doi:

    authors: Spira A,Bajos N,Ducot B

    更新日期:1994-03-01 00:00:00

  • Behavioral risk of human immunodeficiency virus/acquired immunodeficiency syndrome in the university student community.

    abstract:BACKGROUND AND OBJECTIVES:Theoretically, university students could be at especially high risk in a human immunodeficiency virus-type epidemic. Peak incidence of human immunodeficiency virus infection occurs in this age group. GOALS OF THIS STUDY:The purpose of this study was to examine and characterize the behavior, a...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-199503000-00005

    authors: Latman NS,Latman AI

    更新日期:1995-03-01 00:00:00

  • Colonization of the pharynx with Neisseria gonorrhoeae: experience in a clinic for sexually transmitted diseases.

    abstract::At a clinic for treatment of sexually transmitted diseases, 1,453 patients were examined for pharyngeal colonization with Neisseria gonorrhoeae. A history of oral sex was reported by 895 (61.2%) of the patients. N. gonorrhoeae was isolated from the pharynges of 42 (2.9%) of the 1,453 patients. Twenty-seven of the 42 p...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-197910000-00006

    authors: Osborne NG,Grubin L

    更新日期:1979-10-01 00:00:00

  • Vaginal swabs versus lavage for detection of Trichomonas vaginalis and bacterial vaginosis among HIV-positive women.

    abstract:OBJECTIVES:Cervicovaginal lavage (CVL) is often used for research and may be easier and more accurate than vaginal swabs as a specimen collection method. GOAL:The goal of this study was to compare (CVL) with vaginal swabs for the detection of bacterial vaginosis (BV) and Trichomonas vaginalis (TV). STUDY:CVL and vagi...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/01.olq.0000151416.56717.7d

    authors: Kissinger PJ,Dumestre J,Clark RA,Wenthold L,Mohammed H,Hagensee ME,Martin DH

    更新日期:2005-04-01 00:00:00

  • Poor provider adherence to the Centers for Disease Control and Prevention treatment guidelines in US emergency department visits with a diagnosis of pelvic inflammatory disease.

    abstract:BACKGROUND:Pelvic inflammatory disease (PID) is commonly diagnosed in US emergency departments (EDs). We aimed to estimate national rates of provider adherence to the Centers for Disease Control and Prevention (CDC) treatment guidelines for PID among patient visits, with a diagnosis of acute PID in US ED settings. MET...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e31820b8bb4

    authors: Shih TY,Gaydos CA,Rothman RE,Hsieh YH

    更新日期:2011-04-01 00:00:00

  • Help and Care Seeking for Sexually Transmitted Infections Among Youth in Low- and Middle-Income Countries.

    abstract:BACKGROUND:The ability to seek help or medical care for sexually transmitted infections (STIs) is vital for sexually active youth; yet, their needs are often unmet. METHODS:We conducted a qualitative systematic review of studies to assess youth and provider views about the behaviors of young people in help seeking and...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/OLQ.0000000000000607

    authors: Newton-Levinson A,Leichliter JS,Chandra-Mouli V

    更新日期:2017-06-01 00:00:00

  • Level of AIDS and HIV knowledge and sexual practices among sexually transmitted disease patients in China.

    abstract:BACKGROUND:Little is known about sex practices that increase the risk of contracting HIV infection or the level of HIV and AIDS knowledge among sexually transmitted disease (STD) patients in China. OBJECTIVE:To describe AIDS and HIV knowledge, sexual practices, and factors associated with never using condoms among pat...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-200103000-00009

    authors: Wang J,Jiang B,Siegal H,Falck R,Carlson R

    更新日期:2001-03-01 00:00:00

  • Men who have sex with men prefer rapid testing for syphilis and may test more frequently using it.

    abstract::Most Australian men who have sex with men who underwent rapid testing for syphilis using the Determine Syphilis TP immunoassay indicated a preference for rapid testing over conventional serology. Most also indicated that they would test for syphilis more frequently if rapid syphilis testing was available in a clinic s...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/olq.0b013e3181d707de

    authors: Lee D,Fairley C,Cummings R,Bush M,Read T,Chen M

    更新日期:2010-09-01 00:00:00