Analytical specificity and sensitivity of the APTIMA Combo 2 and APTIMA GC assays for detection of commensal Neisseria species and Neisseria gonorrhoeae on the Gen-Probe Panther instrument.

Abstract:

:Genetic detection of Neisseria gonorrhoeae is replacing culture for increased diagnostic sensitivity. Specificity of several nucleic acid amplification tests is suboptimal. Herein, the Gen-Probe APTIMA Combo 2 and APTIMA GC assays had 100% specificity and 100% sensitivity after confirmatory testing, when testing 298 isolates of nongonococcal Neisseria and related species and 205 gonococcal isolates.

journal_name

Sex Transm Dis

authors

Golparian D,Tabrizi SN,Unemo M

doi

10.1097/OLQ.0b013e3182787e45

subject

Has Abstract

pub_date

2013-02-01 00:00:00

pages

175-8

issue

2

eissn

0148-5717

issn

1537-4521

pii

00007435-201302000-00017

journal_volume

40

pub_type

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