Abstract:
:Amniotic fluid is rarely used in the evaluation of syphilis during pregnancy but was available from a woman with positive serologic tests in the 30th week of gestation. Nonmotile intra-amniotic spirochetes were seen by dark-field microscopy 20 hr after treatment with benzathine penicillin G. The identity of the organism in amniotic fluid was confirmed by immunofluorescent staining. Less than 0.5 units/ml of penicillin was present in the amniotic fluid at this time. The amniotic fluid was positive in the Venereal Disease Research Laboratory (VDRL; Atlanta, GA) test, and the concentration of IgM was elevated as was the ratio of lecithin to sphyngomyelin. Phosphatidyl inositol and phosphatidyl glycerol were also present in the amniotic fluid. After treatment the lecithin-sphyngomyelin ratio declined; phosphatidyl glycerol disappeared, whereas phosphatidyl inositol was still present. Despite evidence of intrauterine growth retardation at 30 weeks, the infant born at 37 weeks was of normal weight and length; however, the head circumference was below the tenth percentile. These studies suggest that analysis of amniotic fluid may provide new insights into the biology of syphilis in pregnancy, but does not constitute a recommendation for routine examination of the amniotic fluid in mothers with reactive serologic tests for syphilis.
journal_name
Sex Transm Disjournal_title
Sexually transmitted diseasesauthors
Glover DD,Winter CA,Charles D,Larsen Bdoi
10.1097/00007435-198507000-00010subject
Has Abstractpub_date
1985-07-01 00:00:00pages
145-9issue
3eissn
0148-5717issn
1537-4521journal_volume
12pub_type
杂志文章abstract:BACKGROUND:Sexually transmitted infections (STIs) continue to exert a tremendous health burden on women in developing countries. Poor socioeconomic status, inadequate knowledge, lack of diagnostic facilities, and shortages of effective treatment all contribute to the high incidence of STIs. The use of clinical algorith...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199909000-00010
更新日期:1999-09-01 00:00:00
abstract::Eighty-nine women prostitutes who underwent clinical and microbiologic examination were found to have gonococcal infection. The median age was 22; 92.1% were from urban areas. Nearly all the women prostitutes refrained from barrier methods (92.1%) and had contact with several partners (91.0%). The most frequent clinic...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::This study was undertaken to determine the effectiveness of a single 2.5-g dose of thiamphenicol as therapy for gonococcal infection and to compare the results obtained in a limited group of male and female patients to those reported by other investigators. Diagnosis was determined by direct microscopy and culture. Cu...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198410001-00026
更新日期:1984-10-01 00:00:00
abstract::We present the case of a man with a bicuspid aortic valve who presented with persistent fever. Blood cultures yielded Neisseria gonorrhoeae, and the diagnosis of infected mycotic aneurysm was confirmed by detection of the bacterial genome in the aortic wall. The patient was cured with surgery and intravenous ceftriaxo...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,评审
doi:10.1097/OLQ.0000000000000079
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:The prevalence of human papillomavirus (HPV) infection and the distribution of different HPV genotypes vary greatly within different geographical and ethnic populations, especially in Asia. The HPV infection data based on regional population are extremely important for researchers to develop new efficient HP...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000201
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:Up to 50% of women with nonoptimal vaginal microbial community state type (CST) have bacterial vaginosis (BV). Little is known about what distinguishes women with and without BV diagnosis within nonoptimal CST. We identified features of women and their male sex partners associated with BV among women with no...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000001259
更新日期:2020-12-01 00:00:00
abstract::Our recommended treatment schedule for secondary syphilis is intramuscular benzathine penicillin G, 2.4 million units weekly for two consecutive weeks. If the patient is allergic to penicillin, we recommend that 2 gm of oral tetracycline be given each day for 12 days. Two hundred and four patients with secondary syphi...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-197707000-00005
更新日期:1977-07-01 00:00:00
abstract:OBJECTIVE:To identify factors associated with subsequent sexually transmitted infection (STI) (within 1 year of initial infection) due to Chlamydia trachomatis, Neisseria gonorrhoeae or Trichomonas vaginalis. DESIGN:Prospective cohort study. SETTING:A sexually transmitted diseases clinic and four community-based prim...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199901000-00005
更新日期:1999-01-01 00:00:00
abstract::Three cases of endocarditis caused by Neisseria gonorrhoeae involving the aortic, mitral an tricuspid valves are reported. Two cases in young women, following syndromes suggestive of gonococcal arthritis, presented as acute endocarditis and were fatal. The male patient experienced a subacute course, and the diagnosis ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-197707000-00002
更新日期:1977-07-01 00:00:00
abstract:BACKGROUND:HerpeSelect HSV-1 and HSV-2 ELISAs are glycoprotein G-based, type-specific antibody detection tests that are approved by the US Food and Drug Administration for diagnosis of genital herpes. GOAL:The goal was to determine seroconversion times by means of HerpeSelect ELISAs. STUDY DESIGN:Four-hundred thirtee...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200304000-00007
更新日期:2003-04-01 00:00:00
abstract:OBJECTIVES:To characterize client demographics, sexually transmitted diseases (STD) morbidity, insurance status, reasons for attending public STD clinics, and future preferences for source of STD services. DESIGN:Cross-sectional study of 2,490 clients attending five urban STD clinics for new problems with interviewer-...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199711000-00009
更新日期:1997-11-01 00:00:00
abstract:BACKGROUND:People with multiple sex partners forget a significant proportion of their partners, and drug injectors forget a large proportion of the persons with whom they inject drugs. This incomplete reporting poses a problem for partner notification and social network research on infectious disease. GOAL:To evaluate...
journal_title:Sexually transmitted diseases
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00007435-200111000-00010
更新日期:2001-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Trichomonas vaginalis is one of the most common sexually transmitted infections. In Malawi, rates of trichomoniasis in women are high. The prevalence of T. vaginalis infection in men is expected to be high but has not previously been documented. GOALS:We sought to determine the prevalence of ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199908000-00003
更新日期:1999-08-01 00:00:00
abstract:BACKGROUND:Although the role of concurrent sexual partnerships (i.e., having sexual activity with another partner after a current partnership has been established) has been most strongly associated with the transmission of bacterial sexually transmitted infections, its role in the transmission of viral sexually transmi...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e3181bcd3e7
更新日期:2010-02-01 00:00:00
abstract:BACKGROUND:In October 2009, a quadrivalent vaccine for human papillomavirus (HPV) was licensed in the United States for males aged 9 to 26 years. The attitudes and beliefs of parents play a critical role in uptake of this vaccine because parental consent is typically required for adolescent HPV vaccination. This study ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,随机对照试验
doi:10.1097/OLQ.0b013e318211c248
更新日期:2011-08-01 00:00:00
abstract:OBJECTIVE:To evaluate the outcomes of a partner referral program at the sexually transmitted disease (STD) clinic in Amsterdam that encourages gonorrhea and chlamydia patients to refer their own partners to medical examination. STUDY DESIGN:355 patients with a confirmed infection cooperated in partner referral and gav...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199707000-00005
更新日期:1997-07-01 00:00:00
abstract:BACKGROUND:The burden of sexually transmitted infections (STIs) in areas of sub-Saharan Africa with poor access to health care services is not well documented. In remote areas of South Africa, we investigated the prevalence of STIs and approaches to providing STI services through a mobile clinic. METHODS:We recruited ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000931
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Ciprofloxacin (500 mg orally, single dose) is one of the recommended therapies for gonorrhea in Canada. In Canada, the first ciprofloxacin-resistant (CipR) Neisseria gonorrhoeae strain was isolated in 1993. Antimicrobial susceptibilities of N gonorrhoeae isolates were monitored as part of a national surveill...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,多中心研究
doi:10.1097/00007435-200212000-00008
更新日期:2002-12-01 00:00:00
abstract:BACKGROUND:Sexually transmitted disease (STD) transmission may occur if the time between dissolution and formation of sex partnerships, the gap, is shorter than mean duration of infectivity of STDs. GOAL:The goal was to examine gaps reported by a nationally representative sample of reproductive-age women. STUDY DESIG...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200303000-00009
更新日期:2003-03-01 00:00:00
abstract:BACKGROUND:Human immunodeficiency virus (HIV) and sexually transmitted infections (STI) are prevalent among men who have sex with men (MSM). GOAL:To estimate the prevalence of HIV and STIs in this group. STUDY:A total of 694 MSM were tested for HIV, hepatitis B (HBV), hepatitis C (HCV), human T-cell lymphotropic (HTL...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000194578.06795.2d
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:Studies of sexual behavior and of interventions designed to reduce human immunodeficiency virus risk usually depend on self-report. Validation of self-reported condom use measures has not been previously reported in an urban population at high risk for sexually transmitted diseases and human immunodeficiency...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199501000-00003
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Female-controlled methods of HIV prevention, such as vaginal microbicides, are urgently needed, particularly among drug-involved women. Acceptability research is critical to product development. GOAL:To assess the acceptability of forms and application methods for future microbicides. DESIGN...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200002000-00011
更新日期:2000-02-01 00:00:00
abstract:BACKGROUND:Herpes simplex virus type 2 (HSV-2) is one of the most common sexually transmitted infections and may enhance transmission of HIV. However, population-based estimates of HSV-2 prevalence and correlates of infection are rare. GOALS:To obtain population-based estimates of HSV-2 prevalence and to identify demo...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200008000-00004
更新日期:2000-08-01 00:00:00
abstract:BACKGROUND:Infections by herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2) are common in the United States. Herpes simplex virus type 2 is transmitted sexually, and the prevalence of antibodies to HSV-2 has increased in recent years. GOALS OF THIS STUDY:The objective of the present study was to estimate the ser...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199907000-00004
更新日期:1999-07-01 00:00:00
abstract:BACKGROUND:Little is known about the prevalence and determinants of human papillomavirus (HPV) infection in women from West India, although incidence of and mortality from cervical cancer is high. METHODS:Cervical specimens were collected, and questionnaires on lifestyle and reproductive factors were administered to 2...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e318223be5f
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:Herpes simplex virus-2, the most common cause of genital ulcer disease (GUD) globally, is a cofactor in human immunodeficiency virus type-1 (HIV-1) acquisition and transmission. Current World Health Organization guidelines for sexually transmitted infections recommend acyclovir as first-line syndromic treatm...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e3181e212e5
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND:Antiretroviral therapy effectively reduces the risk of human immunodeficiency virus transmission, but in the context of undetectable equals untransmittable and decreased condom use, rates of syphilis are increasing. In Oregon, syphilis has risen over 20-fold in the past decade, from less than 30 to approxima...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000001015
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:Millions of cases of sexually transmitted infections (STIs) occur in the United States each year, resulting in substantial medical costs to the nation. Previous estimates of the total direct cost of STIs are quite dated. We present updated direct medical cost estimates of STIs in the United States. METHODS:...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e318285c6d2
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVES:Two of the major diagnostic methods for Trichomonas vaginalis, wet mount and culture, rely on the continued viability of the organism. Methods to increase the viability of T. vaginalis in urine are needed. GOAL:The goal of this study was to develop a method that increases the time of viability of T. vaginal...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000249724.72816.a0
更新日期:2007-07-01 00:00:00
abstract:BACKGROUND:Asymptomatic neurosyphilis is more difficult to diagnose in human immunodeficiency virus (HIV)-infected patients because HIV itself can cause cerebrospinal fluid (CSF) pleocytosis. The proportion of CSF lymphocytes that are B cells is elevated in neurosyphilis, suggesting that the CSF concentration of the B ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e3181d877a1
更新日期:2010-05-01 00:00:00