Abstract:
BACKGROUND:Studies of the natural history of genital chlamydial infections in humans are sparse and have had study design limitations. An improved understanding of chlamydial natural history may influence recommendations for elements of control efforts such as chlamydia screening frequency or time parameters for partner notification. METHODS:Addressing limitations of prior studies in part, we are prospectively studying chlamydial natural history in sexually transmitted diseases clinic patients in the interval between screening and returning for treatment of positive chlamydial tests. Results of repeat chlamydial testing and clinical outcomes and their associated predictors are being evaluated. RESULTS:In the initial 129 subjects, 89% were female, 88% were black, median age was 21 years, and the median interval between screening and treatment was 13 days. Based on nucleic acid amplification testing at treatment, spontaneous resolution of chlamydia occurred in 18%. Resolution was somewhat more common in subjects with longer intervals between screening and treatment. Persisting infections more often progressed to develop clinical signs at the time of treatment (e.g., urethritis or cervicitis). Two women and one man developed chlamydial complications between screening and treatment. CONCLUSIONS:Our findings demonstrate that although spontaneous resolution of chlamydia is common, many persons with persisting chlamydia progress to develop signs of infection and some develop complications.
journal_name
Sex Transm Disjournal_title
Sexually transmitted diseasesauthors
Geisler WM,Wang C,Morrison SG,Black CM,Bandea CI,Hook EW 3rddoi
10.1097/OLQ.0b013e318151497dsubject
Has Abstractpub_date
2008-02-01 00:00:00pages
119-23issue
2eissn
0148-5717issn
1537-4521journal_volume
35pub_type
杂志文章abstract:OBJECTIVES:The objectives of this study were to measure frequency and predictors of patient-delivered partner treatment (PDPT) and the frequency of other partner management strategies among New York City healthcare providers (HCPs) as well as to determine whether use of PDPT detracts from other partner management strat...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
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更新日期:2007-02-01 00:00:00
abstract:OBJECTIVES:To describe the reliability of reported dates of first and last sexual exposure, as elicited from sexually transmitted disease/human immunodeficiency virus cases during routine contact investigation, and determine their adequacy for assessing concurrency. METHODS:We used contact tracing data from 5 studies ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000204746.58160.c1
更新日期:2006-05-01 00:00:00
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journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200003000-00008
更新日期:2000-03-01 00:00:00
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journal_title:Sexually transmitted diseases
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doi:10.1097/00007435-200206000-00002
更新日期:2002-06-01 00:00:00
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journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200301000-00018
更新日期:2003-01-01 00:00:00
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journal_title:Sexually transmitted diseases
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doi:10.1097/OLQ.0b013e3182918578
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journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e3181812cdf
更新日期:2008-11-01 00:00:00
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doi:10.1097/OLQ.0b013e318223be5f
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pub_type: 杂志文章,随机对照试验
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journal_title:Sexually transmitted diseases
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2013-02-01 00:00:00
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journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000145851.76025.ad
更新日期:2004-12-01 00:00:00
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pub_type: 杂志文章
doi:10.1097/OLQ.0b013e318239da4e
更新日期:2012-01-01 00:00:00
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更新日期:1999-01-01 00:00:00
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journal_title:Sexually transmitted diseases
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更新日期:2011-03-01 00:00:00
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更新日期:2007-12-01 00:00:00
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pub_type: 临床试验,杂志文章
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pub_type: 杂志文章
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更新日期:2015-09-01 00:00:00
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journal_title:Sexually transmitted diseases
pub_type: 杂志文章
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更新日期:1993-05-01 00:00:00
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更新日期:2000-04-01 00:00:00
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pub_type: 杂志文章
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更新日期:1990-07-01 00:00:00
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