The natural history of untreated Chlamydia trachomatis infection in the interval between screening and returning for treatment.

Abstract:

BACKGROUND:Studies of the natural history of genital chlamydial infections in humans are sparse and have had study design limitations. An improved understanding of chlamydial natural history may influence recommendations for elements of control efforts such as chlamydia screening frequency or time parameters for partner notification. METHODS:Addressing limitations of prior studies in part, we are prospectively studying chlamydial natural history in sexually transmitted diseases clinic patients in the interval between screening and returning for treatment of positive chlamydial tests. Results of repeat chlamydial testing and clinical outcomes and their associated predictors are being evaluated. RESULTS:In the initial 129 subjects, 89% were female, 88% were black, median age was 21 years, and the median interval between screening and treatment was 13 days. Based on nucleic acid amplification testing at treatment, spontaneous resolution of chlamydia occurred in 18%. Resolution was somewhat more common in subjects with longer intervals between screening and treatment. Persisting infections more often progressed to develop clinical signs at the time of treatment (e.g., urethritis or cervicitis). Two women and one man developed chlamydial complications between screening and treatment. CONCLUSIONS:Our findings demonstrate that although spontaneous resolution of chlamydia is common, many persons with persisting chlamydia progress to develop signs of infection and some develop complications.

journal_name

Sex Transm Dis

authors

Geisler WM,Wang C,Morrison SG,Black CM,Bandea CI,Hook EW 3rd

doi

10.1097/OLQ.0b013e318151497d

subject

Has Abstract

pub_date

2008-02-01 00:00:00

pages

119-23

issue

2

eissn

0148-5717

issn

1537-4521

journal_volume

35

pub_type

杂志文章
  • Patient-delivered partner treatment and other partner management strategies for sexually transmitted diseases used by New York City healthcare providers.

    abstract:OBJECTIVES:The objectives of this study were to measure frequency and predictors of patient-delivered partner treatment (PDPT) and the frequency of other partner management strategies among New York City healthcare providers (HCPs) as well as to determine whether use of PDPT detracts from other partner management strat...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/01.olq.0000225322.94613.c2

    authors: Rogers ME,Opdyke KM,Blank S,Schillinger JA

    更新日期:2007-02-01 00:00:00

  • Agreement in reported sexual partnership dates and implications for measuring concurrency.

    abstract:OBJECTIVES:To describe the reliability of reported dates of first and last sexual exposure, as elicited from sexually transmitted disease/human immunodeficiency virus cases during routine contact investigation, and determine their adequacy for assessing concurrency. METHODS:We used contact tracing data from 5 studies ...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/01.olq.0000204746.58160.c1

    authors: Brewer DD,Rothenberg RB,Muth SQ,Roberts JM Jr,Potterat JJ

    更新日期:2006-05-01 00:00:00

  • A Comparison of U.S. Clinical Laboratory Chlamydia and Gonorrhea Testing Practices Prior to and Following the 2014 CDC Testing Recommendations.

    abstract:BACKGROUND:Adherence to recommended laboratory testing practices is crucial for sexually transmitted infection (STI) prevention and control. The objective of this paper is to compare Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) testing practices of US clinical laboratories in 2013 prior to the updated 2014...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0000000000001299

    authors: Davis A,Gaynor A

    更新日期:2020-09-18 00:00:00

  • Prevalence and risk factors for human herpesvirus 8 infection in northern Cameroon.

    abstract:BACKGROUND:The modes of transmission of HHV-8 are still unclear. GOAL:To evaluate the distribution and transmission of HHV-8 infection. DESIGN:Serosurvey conducted in a Cameroon hospital among 292 persons, including children (5-10 years), adolescents (15-20 years), and adults (30-40 years). Antibodies against lytic a...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-200003000-00008

    authors: Rezza G,Tchangmena OB,Andreoni M,Bugarini R,Toma L,Bakary DK,Glikoutou M,Sarmati L,Monini P,Pezzotti P,Ensoli B

    更新日期:2000-03-01 00:00:00

  • A recent increase in the incidence of male urethritis in France.

    abstract:BACKGROUND:At-risk sexual behaviors appear to have increased recently in France, possibly because of the reassuring efficacy of highly active antiretroviral treatments. The objective of this study was to assess the pattern of change. GOAL:The goal was to analyze trends in the incidence of male urethritis, a marker of ...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-200206000-00002

    authors: Massari V,Retel O,Flahault A

    更新日期:2002-06-01 00:00:00

  • Patterns and predictors of female condom use among ethnically diverse women attending family planning clinics.

    abstract:BACKGROUND:The female condom is a viable option for women to protect themselves from HIV infection and other sexually transmitted diseases. GOAL:The goal was to examine the level of female condom use and factors associated with frequency of use among US women living in San Francisco and Oakland, California. STUDY DES...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-200301000-00018

    authors: Choi KH,Gregorich SE,Anderson K,Grinstead O,Gómez CA

    更新日期:2003-01-01 00:00:00

  • No Pathogen-Specific Sign or Symptom Predicts the Etiology of Monomicrobial Nongonococcal Urethritis in Men.

    abstract::Identifying pathogen-specific signs or symptoms of nongonococcal urethritis could improve syndromic management accuracy. We evaluated nongonococcal urethritis signs and symptoms in 220 men with single-pathogen infections (Chlamydia trachomatis, Mycoplasma genitalium, Trichomonas vaginalis, or Ureaplasma urealyticum) o...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0000000000001158

    authors: Jordan SJ,Toh E,Williams JA,Fortenberry LJ,LaPradd M,Ryan JD,Nelson DE,Batteiger TA

    更新日期:2020-05-01 00:00:00

  • Human papillomavirus seropositivity and subsequent risk of HIV acquisition in rural South African women.

    abstract:OBJECTIVE:This study aimed to provide a population-based estimate of human papillomavirus (HPV) seropositivity for women in a rural African context and to evaluate the impact of HPV serostatus on subsequent acquisition of HIV outside a clinical setting. DESIGN:A random sample of women participating in a longitudinal, ...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e3182918578

    authors: Tanser F,Jones KG,Viljoen J,Imrie J,Grapsa E,Newell ML

    更新日期:2013-07-01 00:00:00

  • Observed Treatment Responses to Short-Course Doxycycline Therapy for Rectal Lymphogranuloma Venereum in Men Who Have Sex With Men.

    abstract:BACKGROUND:Lymphogranuloma venereum (LGV) has reestablished itself as an endemic sexually transmitted infection in the United Kingdom and elsewhere in Europe and North America over the last decade. Current guidelines suggest treatment with 21 days of doxycycline; however, the evidence base for LGV treatment including i...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0000000000000772

    authors: Simons R,Candfield S,French P,White JA

    更新日期:2018-06-01 00:00:00

  • Outbreak of Neisseria gonorrhoeae in Northern Alberta, Canada.

    abstract:BACKGROUND:In January 2001 we investigated an outbreak of Neisseria gonorrhoeae in a northern region of Alberta, Canada, and here we report on the epidemiology of the outbreak. GOAL:The goal was to examine the outbreak etiology and make recommendations for strengthening regional STD programs. STUDY DESIGN:Provincial ...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-200306000-00005

    authors: De P,Singh AE,Wong T,Yacoub W

    更新日期:2003-06-01 00:00:00

  • Trends in hepatitis A, B, and shigellosis compared with gonorrhea and syphilis in men who have sex with men in Amsterdam, 1992-2006.

    abstract:BACKGROUND:Since the mid-1990s, sexually transmitted infections (STIs) among men who have sex with men (MSM) have increased and appear to be related to more risky sexual behavior. We compare trends in hepatitis A, acute hepatitis B, and shigellosis with the trends of gonorrhea and infectious syphilis in Amsterdam MSM m...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e3181812cdf

    authors: Van Rijckevorsel GG,Sonder GJ,Bovée LP,Thiesbrummel HF,Geskus RB,Van Den Hoek A

    更新日期:2008-11-01 00:00:00

  • Prevalence and determinants of high-risk human papillomavirus infection in middle-aged Indian women.

    abstract:BACKGROUND:Little is known about the prevalence and determinants of human papillomavirus (HPV) infection in women from West India, although incidence of and mortality from cervical cancer is high. METHODS:Cervical specimens were collected, and questionnaires on lifestyle and reproductive factors were administered to 2...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e318223be5f

    authors: Sauvaget C,Nene BM,Jayant K,Kelkar R,Malvi SG,Shastri SS,Sankaranarayanan R

    更新日期:2011-10-01 00:00:00

  • Uptake of Home-Based Syphilis and Human Immunodeficiency Virus Testing Among Male Partners of Pregnant Women in Western Kenya.

    abstract:BACKGROUND:Few men are tested for syphilis or human immunodeficiency virus (HIV) during their partner's pregnancy, a high-risk period for HIV and syphilis transmission. Offering home-based rapid testing of syphilis to couples during pregnancy can support prevention efforts to reduce transmission of sexually transmitted...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/OLQ.0000000000000649

    authors: Mark J,Kinuthia J,Roxby AC,Krakowiak D,Osoti A,Richardson BA,Gone MA,Asila V,Parikh S,Farquhar C

    更新日期:2017-09-01 00:00:00

  • Randomized controlled trial on the effectiveness of counseling messages for avoiding unprotected sexual intercourse during sexually transmitted infection and reproductive tract infection treatment among female sexually transmitted infection clinic patient

    abstract:BACKGROUND:The effectiveness of counseling messages to avoid unprotected sex during short-term treatment for curable sexually transmitted infections is unknown. METHODS:We randomized 300 female STI clinic patients 18 years or older with cervicitis and/or vaginal discharge in Kingston, Jamaica, in 2010 to 2011, to 1 of...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1097/OLQ.0b013e31827938a1

    authors: Anderson C,Gallo MF,Hylton-Kong T,Steiner MJ,Hobbs MM,Macaluso M,Figueroa JP,Jamieson DJ,Legardy-Williams J,Wiener J,Warner L

    更新日期:2013-02-01 00:00:00

  • Prevalence and incidence of HPV genital infection in women.

    abstract:BACKGROUND:A prophylactic quadrivalent human papillomavirus (HPV) vaccine could benefit adult women if they are susceptible to incident genital HPV infections and are acquiring new infections with vaccine HPV types to which they were previously not exposed. This report presents baseline and prospective data from a rand...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e3181ad25ff

    authors: Velicer C,Zhu X,Vuocolo S,Liaw KL,Saah A

    更新日期:2009-11-01 00:00:00

  • Rate and predictors of new genital warts claims and genital warts-related healthcare utilization among privately insured patients in the United States.

    abstract:BACKGROUND:Little non-clinic-based data are available on incident genital warts rates and related healthcare use. GOAL:: The goal of this study was to describe the incidence and predictors of genital warts and associated healthcare utilization patterns among a group of privately insured patients in the United States. ...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/01.olq.0000145851.76025.ad

    authors: Koshiol JE,Laurent SA,Pimenta JM

    更新日期:2004-12-01 00:00:00

  • Developing a predictive model to prioritize human immunodeficiency virus partner notification in North Carolina.

    abstract:BACKGROUND:Disease intervention specialists (DIS) in North Carolina have less time to conduct partner notification because of competing responsibilities while simultaneously facing increased case loads because of increased human immunodeficiency virus (HIV) testing. We developed a model to predict undiagnosed HIV infec...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e318239da4e

    authors: Hoots BE,MacDonald PD,Hightow-Weidman LB,Leone PA,Miller WC

    更新日期:2012-01-01 00:00:00

  • Subsequent sexually transmitted infections among adolescent women with genital infection due to Chlamydia trachomatis, Neisseria gonorrhoeae, or Trichomonas vaginalis.

    abstract:OBJECTIVE:To identify factors associated with subsequent sexually transmitted infection (STI) (within 1 year of initial infection) due to Chlamydia trachomatis, Neisseria gonorrhoeae or Trichomonas vaginalis. DESIGN:Prospective cohort study. SETTING:A sexually transmitted diseases clinic and four community-based prim...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-199901000-00005

    authors: Fortenberry JD,Brizendine EJ,Katz BP,Wools KK,Blythe MJ,Orr DP

    更新日期:1999-01-01 00:00:00

  • Changing patterns of sexual risk behavior among London gay men: 1998-2008.

    abstract:OBJECTIVES:To examine changes in the sexual behavior of London gay men between 1998 and 2008. METHODS:Gay men using London gyms were surveyed annually between 1998 and 2005, and again in 2008 (n=6064; range, 482-834 per year). Information was collected on human immunodeficiency virus (HIV) status of the respondent, un...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e3181f2ebe1

    authors: Lattimore S,Thornton A,Delpech V,Elford J

    更新日期:2011-03-01 00:00:00

  • Metronidazole-Resistant Trichomoniasis: Beneficial Pharmacodynamic Relationship With High-Dose Oral Tinidazole and Vaginal Paromomycin Combination Therapy.

    abstract::Metronidazole-resistant trichomoniasis is an uncommon condition that presents significant therapeutic challenges. Combination therapy with high-dose oral tinidazole and vaginal paromomycin cream has been uniformly successful. We present a case report of a patient who responded to combination therapy with high-dose ora...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0000000000000903

    authors: Henien M,Nyirjesy P,Smith K

    更新日期:2019-01-01 00:00:00

  • Sexually transmitted diseases and risk behaviors among pregnant women attending inner city public sexually transmitted diseases clinics in Baltimore, MD, 1996-2002.

    abstract:OBJECTIVE:To determine the prevalence of sexually transmitted diseases (STDs) and characterize behavioral correlates among pregnant women attending inner city public STD clinics. STUDY DESIGN:A retrospective study of 2303 pregnant women frequency matched by clinic and year of visit to 2303 nonpregnant women seeking se...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/olq.0b013e31812e6b9a

    authors: Johnson HL,Erbelding EJ,Zenilman JM,Ghanem KG

    更新日期:2007-12-01 00:00:00

  • Susceptibility of Trichomonas vaginalis strains to metronidazole: response to treatment.

    abstract::The effect of the susceptibility of Trichomonas vaginalis strains to metronidazole on response to treatment was determined from minimal inhibitory concentrations (MICs) for organisms isolated during a clinical trial in which single 1- and 2-g doses of metronidazole were compared. Fifty-seven strains were isolated from...

    journal_title:Sexually transmitted diseases

    pub_type: 临床试验,杂志文章

    doi:10.1097/00007435-198307000-00003

    authors: Ralph ED,Darwish R,Austin TW,Smith EA,Pattison FL

    更新日期:1983-07-01 00:00:00

  • Sexually transmitted infections in men in Mumbai slum communities: the relationship of prevalence to risk behavior.

    abstract:OBJECTIVES:The objectives of this study were to identify sexually transmitted infection (STI) prevalence, assess behavioral and symptom correlates, and develop intervention strategies. GOAL:The goal of this study was to conduct one of the first community-based surveys of STI prevalence and risk behaviors among married...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/01.olq.0000249776.92490.32

    authors: Schensul SL,Hawkes S,Saggurti N,Verma RK,Narvekar SS,Nastasi BK,Burleson JA,Risbud A

    更新日期:2007-07-01 00:00:00

  • Seroprevalence of Herpes Simplex Virus Type 1 and Type 2 and Coinfection With HIV and Syphilis: The First National Seroprevalence Survey in Saudi Arabia.

    abstract:BACKGROUND:Herpes simplex virus (HSV) infection is one of the most common viral infections worldwide. Genital herpes is associated with other sexually transmitted infections (STIs) including HIV. Data on prevalence of HSV infections and other STIs in the Kingdom of Saudi Arabia are limited. METHODS:We conducted the fi...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0000000000000336

    authors: Memish ZA,Almasri M,Chentoufi AA,Al-Tawfiq JA,Al-Shangiti AM,Al-Kabbani KM,Otaibi B,Assirri A,Yezli S

    更新日期:2015-09-01 00:00:00

  • What do gay men know about human papillomavirus? Australian gay men's knowledge and experience of anal cancer screening and human papillomavirus.

    abstract:OBJECTIVE:The objective of this study was to determine levels of experience and knowledge concerning anal dysplasia, anal Pap smear tests, and human papillomavirus (HPV) among gay and other homosexually active men. STUDY DESIGN:Three hundred eighty-four men attending a large gay community event in Melbourne completed ...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/01.olq.0000230436.83029.ce

    authors: Pitts MK,Fox C,Willis J,Anderson J

    更新日期:2007-03-01 00:00:00

  • Etiology of acute pelvic inflammatory disease proven by laparoscopy.

    abstract:BACKGROUND:Only a few studies have investigated the etiology of acute pelvic inflammatory disease (PID) in laparoscopy-proven cases using pelvic samples for culture. Most of these studies were conducted in North America and Scandinavia. GOAL OF THE STUDY:To study the microbial etiology of laparoscopy-proven acute pelv...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-199305000-00008

    authors: Dan M,Samra Z,Katz A,Debby A,Gutman R,Zakut H

    更新日期:1993-05-01 00:00:00

  • Identifying opportunities for chlamydia screening among American Indian women.

    abstract::Medical record review was used to identify missed opportunities for chlamydia screening among 103 American Indian/Alaska Native women. Of these, 69% had received a pregnancy test and 74% had received a urine test in the previous 12 months. Chlamydia screening may increase if linked to the other routine clinical testin...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e318222f126

    authors: Taylor MM,Reilley B,Tulloch S,Winscott M,Dunnigan A,Russell M,Redd JT

    更新日期:2011-10-01 00:00:00

  • To notify or not to notify: STD patients' perspectives of partner notification in Seattle.

    abstract:BACKGROUND AND OBJECTIVES:To obtain patients' perspectives on why only some partners are notified in partner-notification programs, the cornerstone of sexually transmitted disease (STD) control, although low proportions of partners are located and evaluated. GOALS:To describe patterns of partner notification reported ...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-200004000-00003

    authors: Gorbach PM,Aral SO,Celum C,Stoner BP,Whittington WL,Galea J,Coronado N,Connor S,Holmes KK

    更新日期:2000-04-01 00:00:00

  • Combination of laser-therapy with 0.5% idoxuridine cream in the treatment of therapy-resistant genital warts in male patients: an open study.

    abstract::Forty heterosexual male patients with therapy resistant penile warts of long duration (mean 12.9 months) were treated with carbon dioxide laser, immediately followed by topical application of 0.5% idoxuridine cream twice daily for 14 days. In case of incomplete or no response to the initial treatment, the treatment pr...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-199007000-00003

    authors: Happonen HP,Lassus A,Santalahti J,Forsstrom S,Lassus J

    更新日期:1990-07-01 00:00:00

  • Perianal Reactivation of Herpes Simplex Virus Type 2 After Laser-Assisted Hair Removal.

    abstract:ABSTRACT:We report a case of perianal reactivation of herpes simplex virus type 2 in a 27-year-old man, who was HIV positive with good immunovirological status, after a laser-assisted (alexandrite) hair removal session. We discuss the clinical and laboratory features and the role of prophylaxis with antivirals, particu...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0000000000001245

    authors: Reis J,Santos FV

    更新日期:2021-02-01 00:00:00