Prevalence and determinants of high-risk human papillomavirus infection in middle-aged Indian women.

Abstract:

BACKGROUND:Little is known about the prevalence and determinants of human papillomavirus (HPV) infection in women from West India, although incidence of and mortality from cervical cancer is high. METHODS:Cervical specimens were collected, and questionnaires on lifestyle and reproductive factors were administered to 27,192 ever-married women aged 30 to 59 years living in a rural area of Maharashtra State, India. HPV-DNA status for high-risk HPV types was assessed using the second-generation hybrid-capture II assay. RESULTS:The prevalence of HPV infection was 10.3% in this population of middle-aged women. High-risk HPV infection was associated with increasing age, low education level, manual work, early age at first sexual intercourse, and widowhood or separation. CONCLUSION:Low socioeconomic status and vulnerable social groups such as widows and separated women are at a higher risk of HPV infection. This study demonstrates once again that HPV infection and subsequent cervical cancer are social diseases.

journal_name

Sex Transm Dis

authors

Sauvaget C,Nene BM,Jayant K,Kelkar R,Malvi SG,Shastri SS,Sankaranarayanan R

doi

10.1097/OLQ.0b013e318223be5f

subject

Has Abstract

pub_date

2011-10-01 00:00:00

pages

902-6

issue

10

eissn

0148-5717

issn

1537-4521

pii

00007435-201110000-00004

journal_volume

38

pub_type

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