Abstract:
:Given the many options available, selecting an HIV test for a particular clinical or research setting can be daunting. Making an informed decision requires an assessment of the likelihood of acute infection in the test population and an understanding of key aspects of the tests themselves. The ability of individual tests to reliably detect HIV infection depends on the target(s) being detected, when they can be expected to be present after infection, and the concentration of stable target in test specimens, all of which are explained by the virologic and serologic events after infection. The purpose of this article is to review the timeline of HIV infection, nomenclature, and characteristics of different tests; compare point-of-care and laboratory-based tests; discuss the impact of different specimens on test performance; and provide practical advice to help clinicians and researchers new to the field select a test that best suits their needs.
journal_name
Sex Transm Disjournal_title
Sexually transmitted diseasesauthors
Hurt CB,Nelson JAE,Hightow-Weidman LB,Miller WCdoi
10.1097/OLQ.0000000000000719subject
Has Abstractpub_date
2017-12-01 00:00:00pages
739-746issue
12eissn
0148-5717issn
1537-4521pii
00007435-201712000-00005journal_volume
44pub_type
杂志文章,评审abstract:BACKGROUND:We previously demonstrated a decrease in bacterial vaginosis (BV) and an increase in Lactobacillus colonization among randomized controlled trial (RCT) participants who received monthly oral periodic presumptive treatment (PPT; 2 g metronidazole + 150 mg fluconazole). Posttrial data were analyzed to test the...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,随机对照试验
doi:10.1097/OLQ.0b013e31824790d7
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to assess whether providing a choice of condoms would increase condom acceptability, increase self-reported use, and decrease incident sexually transmitted infection. STUDY:We randomized 414 men presenting with urethral discharge in Jamaica to receive either the "standard" cli...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,随机对照试验
doi:10.1097/01.olq.0000187200.07639.c6
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE/GOAL:The objective of this study was to examine sildenafil (Viagra) use and its relationship to sexual risk behavior for HIV and sexually transmitted diseases among men who have sex with men (MSM). STUDY:A population-based telephone sample of MSM in San Francisco was interviewed about sexual behavior, substa...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000175294.76494.77
更新日期:2005-09-01 00:00:00
abstract:OBJECTIVE:Risk factors for bacterial vaginosis (BV) include douching and sexual activity, although the exact cause of BV is unknown. GOAL:The goal of this study was to determine the relative significance of douching as a risk factor for BV. STUDY DESIGN:Two hundred fifty adolescent women who regularly douched were en...
journal_title:Sexually transmitted diseases
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/01.olq.0000129948.91055.9f
更新日期:2004-07-01 00:00:00
abstract:OBJECTIVES:To determine the attitudes of male and female patients to the use of chaperones during genital examination within a sexually transmitted diseases clinic. STUDY DESIGN:An anonymous, self-completed questionnaire was administered to patients attending the Melbourne Sexual Health Centre, Australia, between Sept...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e3180ca8f3a
更新日期:2007-12-01 00:00:00
abstract:BACKGROUND:Calls for increased investment in sexually transmitted infection (STI) treatment across the developing world have been made to address the high disease burden and the association with HIV transmission. GOALS:The goals of this study were to systematically review evidence on the cost of treating curable STIs ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,评审
doi:10.1097/01.olq.0000235177.30718.84
更新日期:2006-10-01 00:00:00
abstract:OBJECTIVES:A sharp increase in the incidence of gonorrhea has been observed in Tel Aviv, Israel, since 1999. Almost one half of interviewed patients admitted contracting the infection from a sex worker. In two thirds of the cases, oral sex (fellatio) was the most probable route of acquiring the disease. In the current ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000204675.92459.3c
更新日期:2006-08-01 00:00:00
abstract:BACKGROUND:The use of sexual network analysis has the potential to further our understanding of sexually tranmitted disease (STD) epidemics and contribute to the development of more effective targeted control strategies. GOAL:To use sexual network analysis to study transmission patterns of chlamydia and gonorrhea in M...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200101000-00005
更新日期:2001-01-01 00:00:00
abstract::In the cases of two patients and in a rabbit with experimental syphilis, treatment of primary syphilis lesions with 5% acyclovir ointment did not affect detection of Treponema pallidum by dark-field microscopy. These results indicate that the dark-field examination need not be delayed in patients whose genital ulcers ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198311000-00008
更新日期:1983-10-01 00:00:00
abstract:BACKGROUND:Antiretroviral therapy effectively reduces the risk of human immunodeficiency virus transmission, but in the context of undetectable equals untransmittable and decreased condom use, rates of syphilis are increasing. In Oregon, syphilis has risen over 20-fold in the past decade, from less than 30 to approxima...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000001015
更新日期:2019-08-01 00:00:00
abstract::The implementation of express testing in an sexually transmitted infection (STI) clinic reduced the length of visit time compared with other visit types and increased the proportion of STIs diagnosed at clinic visits. Express testing did not impact the time to treatment for asymptomatic patients diagnosed as having an...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000363
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND:Human immunodeficiency virus self-testing (HIVST) holds great promise for reaching high-risk key populations who do not access facility-based services. We sought to characterize unsupervised HIVST implementation among men who have sex with men in China. METHODS:We conducted a nationwide online survey in Chi...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000581
更新日期:2017-04-01 00:00:00
abstract::To define the performance characteristics of two newer tests for Trichomonas vaginalis (TV), the authors compared direct fluorescent antibody (DFA) (mixed monoclonal antibody, Integrated Diagnostics, Inc, Berkeley, CA) and acridine orange (AO) tests to standard wet mount (WM) preparations and culture (modified Diamond...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198907000-00002
更新日期:1989-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The pathogenesis of chancroid is currently unclear. There are discrepancies between the virulence of Haemophilus ducreyi in the human and animal experiments. Iron availability influences the virulence of many pathogens. The objective of this study was to investigate the role of iron in virulen...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199702000-00002
更新日期:1997-02-01 00:00:00
abstract:BACKGROUND:Youth in detention represent a medically underserved population at risk for a variety of medical and emotional disorders. GOAL OF THE STUDY:To determine prevalence of STDs and high-risk sexual behaviors for HIV/STD among adolescent males admitted to a juvenile detention facility. STUDY DESIGN:Cross-section...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199405000-00001
更新日期:1994-05-01 00:00:00
abstract:ABSTRACT:We report a case of perianal reactivation of herpes simplex virus type 2 in a 27-year-old man, who was HIV positive with good immunovirological status, after a laser-assisted (alexandrite) hair removal session. We discuss the clinical and laboratory features and the role of prophylaxis with antivirals, particu...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000001245
更新日期:2021-02-01 00:00:00
abstract:BACKGROUND:This study examined condom use and sexually transmitted infection (STI) testing among unmarried, non-cohabiting women and men who had multiple past-year partnerships or perceived their partner's involvement in another sexual relationship. METHODS:We identified 5868 and 5330 unmarried, non-cohabiting sexuall...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000001067
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVES:To describe the impact of surveillance for antimicrobial resistance (AMR) in Neisseria gonorrhoeae over a 7-year period on treatment guidelines in Alberta, Canada. METHODS:AMR testing data from gonorrhea cases were combined with demographic and risk behavior information collected through surveillance to des...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e3181aad9df
更新日期:2009-10-01 00:00:00
abstract::The objective of this study was to develop and apply a serologic method for identification of different strains of Neisseria gonorrhoeae. Several procedures for preparation of cell-free extracts were tried; the most satisfactory was that with phosphate-buffered saline solution. Both capillary tube and immunodiffusion ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198004000-00002
更新日期:1980-04-01 00:00:00
abstract::We believe this to be the first report of coexisting polymerase chain reaction (PCR)-confirmed primary genital and ocular syphilis in a patient with penicillin allergy treated with doxycycline. The case examines the use of nonpenicillin and corticosteroid treatment of ocular syphilis and highlights the risk of eye inv...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000900
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:High rates of sexually transmitted diseases (STDs) present an ongoing costly public health challenge. One approach to reduce STD transmission is to increase the number of clinicians adopting the Centers for Disease Control and Prevention's STD Treatment Guidelines. This evaluation assesses the effectiveness ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e3182045306
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:Only a few studies have investigated the etiology of acute pelvic inflammatory disease (PID) in laparoscopy-proven cases using pelvic samples for culture. Most of these studies were conducted in North America and Scandinavia. GOAL OF THE STUDY:To study the microbial etiology of laparoscopy-proven acute pelv...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199305000-00008
更新日期:1993-05-01 00:00:00
abstract:BACKGROUND:Syphilis rates are rising in California, but the impact of HIV infection on syphilis infection remains uncertain. We describe differences between HIV-infected and HIV-uninfected patients diagnosed with syphilis within Kaiser Permanente Northern California. METHODS:We performed retrospective analyses of pati...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e3181b6f0cc
更新日期:2010-01-01 00:00:00
abstract::Among 413 Nigerian men who have sex with men and transgender women, retrospective testing for Mycoplasma genitalium revealed mostly asymptomatic infections of the anorectum (prevalence, 36.8%; incidence, 18.4 cases/100 person-years) and urogenital tract (12.4%, 4.0 cases/100 person-years). Risk factors included HIV an...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000001105
更新日期:2020-03-01 00:00:00
abstract::Culture of urethral specimens from a 21-year-old man with nongonococcal urethritis yielded both Chlamydia trachomatis and a minocycline-resistant strain of Ureaplasma urealyticum. In such situations, the causal agent of the urethritis is frequently considered to be C. trachomatis. However, the etiology of this case wa...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:
更新日期:1983-07-01 00:00:00
abstract:BACKGROUND:American Indian and Alaska Natives suffer pervasive health disparities, including disproportionately high rates of HIV. Sexual network dynamics, including concurrency and sexual mixing patterns, are key determinants of HIV disparities. METHODS:We analyzed data from the first national study of gay, lesbian, ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e3181c37e3e
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:Little is known about sex practices that increase the risk of contracting HIV infection or the level of HIV and AIDS knowledge among sexually transmitted disease (STD) patients in China. OBJECTIVE:To describe AIDS and HIV knowledge, sexual practices, and factors associated with never using condoms among pat...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200103000-00009
更新日期:2001-03-01 00:00:00
abstract:BACKGROUND:Evaluating chlamydia prevalence trends from sentinel surveillance is important for understanding population disease burden over time. However, prevalence trend estimates from surveillance data may be misleading if they do not account for changes in risk profiles of individuals who are screened (case mix) and...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000798
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND & OBJECTIVES:To describe partner notification practices for chlamydial infections among private sector clinicians. STUDY DESIGN:Telephone interviews of clinicians and patients identified through public health case reports in Seattle-King County, August-October 1998. RESULTS:Clinicians reported advising 135...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199910000-00011
更新日期:1999-10-01 00:00:00
abstract:BACKGROUND:Infectious syphilis has increased substantially over the past decade. Targeting limited public health resources toward subpopulations with multiple reinfections may have a large impact in reducing onward transmission within a community. METHODS:A chart review was conducted for individuals with 4 or more inf...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000995
更新日期:2019-07-01 00:00:00