Abstract:
OBJECTIVES:To describe the impact of surveillance for antimicrobial resistance (AMR) in Neisseria gonorrhoeae over a 7-year period on treatment guidelines in Alberta, Canada. METHODS:AMR testing data from gonorrhea cases were combined with demographic and risk behavior information collected through surveillance to describe trends and sequential changes to treatment guidelines. RESULTS:Ciprofloxacin resistant gonorrhea (CRG) cultures rose from 1.4% in 2001 to 27.7% in 2007. Of 200 CRG cases, 90% were men, 77% white, median age 29 years (interquartile range: 23-29 years) and 60% were men who have sex with men (MSM). In 2005, only 1 of 28 cases did not fit into travel or MSM categories and treatment guidelines were changed to recommend oral cefixime as the preferred agent in MSM or those with a travel history. Continuous rise in CRG together with locally acquired cases among heterosexuals resulted in ciprofloxacin being removed as a recommended agent for gonorrhea in 2007. CONCLUSIONS:Our data underscores the importance of surveillance in monitoring trends in AMR in gonorrhea so that timely changes to treatment recommendations can be made in response to changing epidemiology.
journal_name
Sex Transm Disjournal_title
Sexually transmitted diseasesauthors
Plitt S,Boyington C,Sutherland K,Lovgren M,Tilley P,Read R,Singh AEdoi
10.1097/OLQ.0b013e3181aad9dfsubject
Has Abstractpub_date
2009-10-01 00:00:00pages
665-9issue
10eissn
0148-5717issn
1537-4521journal_volume
36pub_type
杂志文章abstract:BACKGROUND:Calls for increased investment in sexually transmitted infection (STI) treatment across the developing world have been made to address the high disease burden and the association with HIV transmission. GOALS:The goals of this study were to systematically review evidence on the cost of treating curable STIs ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,评审
doi:10.1097/01.olq.0000235177.30718.84
更新日期:2006-10-01 00:00:00
abstract:BACKGROUND:Project SAFE, a gender- and culture-specific cognitive-behavioral intervention, was one of the few interventions to have demonstrated a significant reduction in sexually transmitted infections in a randomized, controlled trial. GOAL:We evaluated intervention efficacy in 379 Mexican Americans and 170 African...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000115461.50698.55
更新日期:2004-03-01 00:00:00
abstract::Nonspecific vaginitis (NSV) is a clinical syndrome characterized by a decreased concentration of normal acidophilic Döderlein flora in the vagina and increased concentration of nonacidophilic microorganisms, such as Gardnerella vaginalis, anaerobic bacteria, and mycoplasmas. Since several NSV-associated organisms are ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198601000-00002
更新日期:1986-01-01 00:00:00
abstract::Ureaplasma urealyticum strains isolated from urethral specimens of 112 patients with nongonococcal urethritis, 17 with gonorrhea, and 33 asymptomatic carriers (controls) were tested by the growth-inhibition test with standard ureaplasma antisera (serotypes 1-8). Cases with more than one serotype (two to four types) we...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198510000-00010
更新日期:1985-10-01 00:00:00
abstract:OBJECTIVES:To examine changes in the sexual behavior of London gay men between 1998 and 2008. METHODS:Gay men using London gyms were surveyed annually between 1998 and 2005, and again in 2008 (n=6064; range, 482-834 per year). Information was collected on human immunodeficiency virus (HIV) status of the respondent, un...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e3181f2ebe1
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:Antiretroviral therapy effectively reduces the risk of human immunodeficiency virus transmission, but in the context of undetectable equals untransmittable and decreased condom use, rates of syphilis are increasing. In Oregon, syphilis has risen over 20-fold in the past decade, from less than 30 to approxima...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000001015
更新日期:2019-08-01 00:00:00
abstract::The effect of the susceptibility of Trichomonas vaginalis strains to metronidazole on response to treatment was determined from minimal inhibitory concentrations (MICs) for organisms isolated during a clinical trial in which single 1- and 2-g doses of metronidazole were compared. Fifty-seven strains were isolated from...
journal_title:Sexually transmitted diseases
pub_type: 临床试验,杂志文章
doi:10.1097/00007435-198307000-00003
更新日期:1983-07-01 00:00:00
abstract:BACKGROUND:Chlamydia notifications are increasing in Australia, and the use of a computer alert prompting general practitioners to test young women is a potential way to increase opportunistic chlamydia testing. The aim of this trial was to determine the effectiveness of a computer alert in general practice on chlamydi...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,随机对照试验
doi:10.1097/OLQ.0b013e3181cfcb4c
更新日期:2010-07-01 00:00:00
abstract::The susceptibility of Chlamydia trachomatis to antibiotics was studied in vitro and in patients with nongonococcal urethritis. The minimal inhibitory concentrations of cloxacillin, erythromycin, pivampicillin, oxytetracycline, and doxycycline, which were the most effective drugs, were 10, 0.5, 0.25, 0.1, and 0.5 micro...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-197904000-00002
更新日期:1979-04-01 00:00:00
abstract:OBJECTIVES:This study examined serologic markers of hepatitis B virus (HBV) infection and immunity among young Asian/Pacific Islander men who have sex with men (API MSM) in San Francisco. METHODS:Participants were 496 API MSM, aged 18 to 29 years, recruited to participate in a cross-sectional survey using a random, ve...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000148296.93945.53
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:Little non-clinic-based data are available on incident genital warts rates and related healthcare use. GOAL:: The goal of this study was to describe the incidence and predictors of genital warts and associated healthcare utilization patterns among a group of privately insured patients in the United States. ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000145851.76025.ad
更新日期:2004-12-01 00:00:00
abstract:OBJECTIVE:To determine the prevalence of sexually transmitted diseases (STDs) and characterize behavioral correlates among pregnant women attending inner city public STD clinics. STUDY DESIGN:A retrospective study of 2303 pregnant women frequency matched by clinic and year of visit to 2303 nonpregnant women seeking se...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/olq.0b013e31812e6b9a
更新日期:2007-12-01 00:00:00
abstract:BACKGROUND:Studies of alcohol use and sexual behavior in African populations have primarily been cross-sectional, used nonvalidated measures of alcohol use, or relied on self-reported sexual risk endpoints. Few have focused on human immunodeficiency virus (HIV)-positive women. METHODS:Longitudinal data were collected ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000502
更新日期:2016-10-01 00:00:00
abstract::This review of the treatment of patients exposed to gonorrhea uses decision analysis techniques to estimate and compare the probabilities of disease and treatment risks for epidemiologic treatment, for treatment contingent on results of gram stains and culture, and for treatment contingent on culture results alone. E...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-197904000-00022
更新日期:1979-04-01 00:00:00
abstract:BACKGROUND:Oral human papillomavirus (HPV) infection is a cause of oropharyngeal squamous cell carcinoma, yet little is known about the epidemiology and natural history of infection. METHODS:At a baseline and 3-month follow-up visit, 1000 young adults aged 18 to 30 years provided an oral rinse sample and completed a s...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e31824f1c65
更新日期:2012-07-01 00:00:00
abstract:BACKGROUND:Despite antiretroviral therapy (ART), incident human immunodeficiency virus (HIV) continues to rise, and sexually transmitted infections (STI) are well known for their part in HIV transmission. National guidelines recommend routine STI screening in HIV-positive individuals, but despite this, reported uptake ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e31822e6136
更新日期:2011-12-01 00:00:00
abstract:OBJECTIVES:Model impact of increasing screening and partner notification (PN) on chlamydia positivity. METHODS:We used a stochastic simulation model describing pair formation and dissolution in an age-structured heterosexual population. The model accounts for steady, casual, and concurrent partnerships and a highly se...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e31824e52c2
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:HIV counseling prevents sexually transmitted diseases (STDs), with most of the benefit accumulating in the first 6 months. STUDY:The authors conducted a multicenter, randomized, controlled trial of a 20-minute additional (booster) counseling session 6 months after HIV counseling compared with no additional ...
journal_title:Sexually transmitted diseases
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1097/01.olq.0000151420.92624.c0
更新日期:2005-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Neurocognitive impairment is common in human immunodeficiency virus (HIV)-infected subjects. The relationship of sexually transmitted diseases to neurocognitive changes is unknown. GOAL:To establish whether HIV-infected patients with a history of syphilis or gonorrhea have a higher rate of ne...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199708000-00003
更新日期:1997-08-01 00:00:00
abstract:OBJECTIVE:To estimate annual costs of a multifaceted adolescent sexual health intervention in Mwanza, Tanzania, by input (capital and recurrent), component (in-school, community activities, youth-friendly health services, condom distribution), and phase (development, startup, trial implementation, scale-up). STUDY DES...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000200606.98181.42
更新日期:2006-10-01 00:00:00
abstract:BACKGROUND:The burden of sexually transmitted infections (STIs) in areas of sub-Saharan Africa with poor access to health care services is not well documented. In remote areas of South Africa, we investigated the prevalence of STIs and approaches to providing STI services through a mobile clinic. METHODS:We recruited ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000931
更新日期:2019-03-01 00:00:00
abstract::Three different brief intervention programs to promote condom use were tested among patients in inner-city sexually transmitted disease (STD) clinics. The first, "Condom Skills," focused on teaching mechanical aspects of how to use a condom. The second, "Social Influences," emphasized how to negotiate condom use with ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199209000-00002
更新日期:1992-09-01 00:00:00
abstract:BACKGROUND:US Food and Drug Administration-approved enzyme-linked immunoassays (EIA) for determining type-specific herpes simplex virus (HSV) serostatus are widely used in clinical practice. We compared the performance of such assays with the University of Washington Western blot (UW WB) in patients who sought confirma...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000689
更新日期:2017-12-01 00:00:00
abstract::Multidrug-resistant Neisseria gonorrhoeae infections have been declared 1 of the top 3 urgent threats to public health. Approaches to combat resistance include targeted therapy with antibiotics previously thought to be ineffective, made possible by rapid molecular assays to predict susceptibility. Previous studies hav...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,meta分析,评审
doi:10.1097/OLQ.0000000000000591
更新日期:2017-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Interpreting the results of any study requires careful analysis to determine how selective participation may have influenced the findings. Participation in a study of sexual behavior may be influenced by who is doing the study, who the participants are, what it means to participate, what the s...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,评审
doi:10.1097/00007435-199505000-00007
更新日期:1995-05-01 00:00:00
abstract:ABSTRACT:We report a case of perianal reactivation of herpes simplex virus type 2 in a 27-year-old man, who was HIV positive with good immunovirological status, after a laser-assisted (alexandrite) hair removal session. We discuss the clinical and laboratory features and the role of prophylaxis with antivirals, particu...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000001245
更新日期:2021-02-01 00:00:00
abstract::A new variant of Chlamydia trachomatis (nvCT) was discovered in Sweden in 2006, and it could not be detected by diagnostic systems from Abbott and Roche, whereas the third system used, from Becton Dickinson (BD), detects nvCT. We analyzed 3648 samples from 2 counties that used Roche and 2 counties that used BD methods...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e3182593be7
更新日期:2012-08-01 00:00:00
abstract::Specimens of urethral exudate from 200 men with uncomplicated urethritis were tested for Neisseria gonorrhoeae by the limulus amebocyte lysate assay, culture on modified Thayer-Martin medium, and gram-stained smear. As compared with cultures, the sensitivity and specificity of the limulus assay were 94.8% and 89.3%, r...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198107000-00001
更新日期:1981-07-01 00:00:00
abstract:INTRODUCTION:As the incidence of hepatitis C virus (HCV) infections remains high among human immunodeficiency virus (HIV)-positive men who have sex with men (MSM) an HCV testing strategy was introduced at the sexually transmitted infections (STI) clinic in Amsterdam in 2017. We aimed to evaluate this HCV testing strate...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000001223
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Small ethnographic and clinic-based studies indicate that crack-smoking sex workers are at high risk for human immunodeficiency virus (HIV) and sexually transmitted diseases (STD). STUDY GOALS:To examine the prevalence of risky sexual behaviors and HIV and STD in a large sample of street-recr...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199804000-00002
更新日期:1998-04-01 00:00:00