Abstract:
BACKGROUND:Infectious syphilis has increased substantially over the past decade. Targeting limited public health resources toward subpopulations with multiple reinfections may have a large impact in reducing onward transmission within a community. METHODS:A chart review was conducted for individuals with 4 or more infectious syphilis diagnoses between 2005 and 2014 (the top 1% of all syphilis diagnoses in British Columbia, Canada). We characterized the sociodemographics, partner notification outcomes and social network. RESULTS:Between 2005 and 2014, there were 30 individuals with 4 or more syphilis diagnoses, accounting for 139 diagnoses. All were men who have sex with men and 29 (96%) were human immunodeficiency virus-positive. Of the 139 diagnoses, 65% occurred in the early latent stage of infection, 22% in the secondary stage, and 14% in the primary stage. The median number of sexual partners per diagnosis was 5 (range, 1-50). Among the 838 partners reported, 79% were notifiable, 53% were notified, and 23% were reported to be tested or treated. Sexual network mapping showed that almost half of the members of this group could be linked to one another either directly or indirectly via partners over 10 years. Social network mapping demonstrated high connectivity, with 4 venues associated with almost two thirds of the study population. CONCLUSIONS:The connectivity and recurrent diagnoses in this study population suggest potential benefits of targeted interventions to individuals with multiple diagnoses and their partners. Our study highlights the need for enhanced care, increased syphilis testing frequency, and exploring alternative preventative methods among individuals with syphilis rediagnoses to reduce syphilis incidence.
journal_name
Sex Transm Disjournal_title
Sexually transmitted diseasesauthors
Konrad S,Mak DB,Grennan T,Zakher B,Brownrigg B,Ogilvie G,Morshed M,Tyndall M,Gilbert M,Krajden M,Wong Jdoi
10.1097/OLQ.0000000000000995subject
Has Abstractpub_date
2019-07-01 00:00:00pages
423-428issue
7eissn
0148-5717issn
1537-4521journal_volume
46pub_type
杂志文章abstract:OBJECTIVES:Screening women for Chlamydia trachomatis (CT) infection using selective screening criteria has been operational in the northwestern United States (Region X) since 1988. Changes in the field, including declines in CT prevalence, introduction of sensitive laboratory tests, and budgetary pressures necessitate ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000124613.85111.6b
更新日期:2004-05-01 00:00:00
abstract:BACKGROUND:Calls for increased investment in sexually transmitted infection (STI) treatment across the developing world have been made to address the high disease burden and the association with HIV transmission. GOALS:The goals of this study were to systematically review evidence on the cost of treating curable STIs ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,评审
doi:10.1097/01.olq.0000235177.30718.84
更新日期:2006-10-01 00:00:00
abstract::In the cases of two patients and in a rabbit with experimental syphilis, treatment of primary syphilis lesions with 5% acyclovir ointment did not affect detection of Treponema pallidum by dark-field microscopy. These results indicate that the dark-field examination need not be delayed in patients whose genital ulcers ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198311000-00008
更新日期:1983-10-01 00:00:00
abstract:BACKGROUND:The effectiveness of counseling messages to avoid unprotected sex during short-term treatment for curable sexually transmitted infections is unknown. METHODS:We randomized 300 female STI clinic patients 18 years or older with cervicitis and/or vaginal discharge in Kingston, Jamaica, in 2010 to 2011, to 1 of...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/OLQ.0b013e31827938a1
更新日期:2013-02-01 00:00:00
abstract:BACKGROUND:Serosorting is the practice of choosing sex partners or selectively using condoms based on a sex partner's perceived HIV status. The extent to which serosorting protects African American (AA) and Hispanic men who have sex with men (MSM) is unknown. METHODS:We analyzed data collected from MSM sexually transm...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e31825727cb
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVE:To compare self-reported doxycycline compliance in men and women attending an STD clinic with indications for Chlamydia trachomatis treatment to compliance measured using microprocessor-containing medication vials to count each time and date medication vials were opened. A secondary objective was to correlate...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199905000-00006
更新日期:1999-05-01 00:00:00
abstract:OBJECTIVES:To determine the attitudes of male and female patients to the use of chaperones during genital examination within a sexually transmitted diseases clinic. STUDY DESIGN:An anonymous, self-completed questionnaire was administered to patients attending the Melbourne Sexual Health Centre, Australia, between Sept...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e3180ca8f3a
更新日期:2007-12-01 00:00:00
abstract::Selected results from a recent study on sexual behavior in the United States are presented, focusing on the association between sexual behavior, disease prevention, and STD outcome. The data are from national household samples of adult men and women. The results show that a sizeable proportion of the U.S. adult popula...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:
更新日期:1994-03-01 00:00:00
abstract::The case of a young man with condylomata lata in the toewebs of both feet is presented. Treponema pallidum was identified in these lesions. Examination two weeks after intramuscular injection of 2.4 X 10(6) units of benzathine penicillin showed resolution of the lesions on the toewebs. ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198407000-00010
更新日期:1984-07-01 00:00:00
abstract:OBJECTIVE:To examine the effect of a laboratory-confirmed Chlamydia trachomatis (Ct) test result on subsequent sexual risk behavior in a large population-based screening program. METHODS:The study population consisted of 16- to 29-year-old participants of the Chlamydia Screening Implementation who completed Ct testing...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000234
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:This study describes self-reported histories of sexually transmitted diseases (STD) with respect to gender and ethnicity and examines the factors that influence the use of condoms among heterosexual users of injection drugs and/or crack cocaine. STUDY DESIGN:A cross-sectional design was used ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,多中心研究
doi:10.1097/00007435-199607000-00006
更新日期:1996-07-01 00:00:00
abstract:BACKGROUND:Studies of alcohol use and sexual behavior in African populations have primarily been cross-sectional, used nonvalidated measures of alcohol use, or relied on self-reported sexual risk endpoints. Few have focused on human immunodeficiency virus (HIV)-positive women. METHODS:Longitudinal data were collected ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000502
更新日期:2016-10-01 00:00:00
abstract::Identifying pathogen-specific signs or symptoms of nongonococcal urethritis could improve syndromic management accuracy. We evaluated nongonococcal urethritis signs and symptoms in 220 men with single-pathogen infections (Chlamydia trachomatis, Mycoplasma genitalium, Trichomonas vaginalis, or Ureaplasma urealyticum) o...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000001158
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:Nucleic acid amplification tests permit widespread screening for Chlamydia trachomatis. However, the public health benefit of screening may be reduced by high chlamydia incidence and repeat infection rates. GOAL:To study chlamydia incidence and repeat infection among clients of a sexually transmitted diseas...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200202000-00001
更新日期:2002-02-01 00:00:00
abstract::Metronidazole-resistant trichomoniasis is an uncommon condition that presents significant therapeutic challenges. Combination therapy with high-dose oral tinidazole and vaginal paromomycin cream has been uniformly successful. We present a case report of a patient who responded to combination therapy with high-dose ora...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000903
更新日期:2019-01-01 00:00:00
abstract::Between 1988 and 1991, 64 homosexual men and 43 bisexual men were screened for human immunodeficiency virus (HIV) in Southern Taiwan; 5 of them were found to carry HIV antibodies. According to a self-administered questionnaire completed before screening, the average age of the men in the study group was 27 years, and ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:
更新日期:1992-11-01 00:00:00
abstract::The implementation of express testing in an sexually transmitted infection (STI) clinic reduced the length of visit time compared with other visit types and increased the proportion of STIs diagnosed at clinic visits. Express testing did not impact the time to treatment for asymptomatic patients diagnosed as having an...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000363
更新日期:2015-11-01 00:00:00
abstract:OBJECTIVE:To identify factors associated with subsequent sexually transmitted infection (STI) (within 1 year of initial infection) due to Chlamydia trachomatis, Neisseria gonorrhoeae or Trichomonas vaginalis. DESIGN:Prospective cohort study. SETTING:A sexually transmitted diseases clinic and four community-based prim...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199901000-00005
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The increasing prevalence of resistant strains of Neisseria gonorrhoeae has prompted investigation of new agents for the treatment of this sexually transmitted disease. GOAL OF THIS STUDY:This study compared the efficacy and safety of a single oral dose of enoxacin to intramuscular ceftriaxon...
journal_title:Sexually transmitted diseases
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00007435-199307000-00008
更新日期:1993-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:To investigate in a cross-sectional study the determinants of oral human papillomavirus infection in 287 individuals who are sexually active. GOAL:To assess prevalence as well as risk factors for oral human papillomavirus infection. STUDY DESIGN:One hundred seventy-eight human immunodeficien...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199701000-00006
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Since 2003, outbreaks of lymphogranuloma venereum (LGV) with anorectal syndrome have been increasingly recognized in many Western countries. All of them have been classified as LGV serovar L2b, mainly occurring in human immunodeficiency virus (HIV)-infected men who have had sex with men (MSM). We describe a ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000459
更新日期:2016-07-01 00:00:00
abstract::Most Australian men who have sex with men who underwent rapid testing for syphilis using the Determine Syphilis TP immunoassay indicated a preference for rapid testing over conventional serology. Most also indicated that they would test for syphilis more frequently if rapid syphilis testing was available in a clinic s...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/olq.0b013e3181d707de
更新日期:2010-09-01 00:00:00
abstract::Culture of urethral specimens from a 21-year-old man with nongonococcal urethritis yielded both Chlamydia trachomatis and a minocycline-resistant strain of Ureaplasma urealyticum. In such situations, the causal agent of the urethritis is frequently considered to be C. trachomatis. However, the etiology of this case wa...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:
更新日期:1983-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Theoretically, university students could be at especially high risk in a human immunodeficiency virus-type epidemic. Peak incidence of human immunodeficiency virus infection occurs in this age group. GOALS OF THIS STUDY:The purpose of this study was to examine and characterize the behavior, a...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199503000-00005
更新日期:1995-03-01 00:00:00
abstract:BACKGROUND:Hepatitis C virus (HCV) is a major global problem, transmitted primarily by percutaneous exposure to contaminated blood. GOAL:The goal of the study was to determine the seroprevalence of and risk factors for HCV among patients attending two urban STD clinics in Alberta. STUDY DESIGN:Anonymous unlinked sero...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200301000-00008
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:Errors in the classification of male circumcision status could bias studies linking infection to lack of circumcision. GOAL:To determine the frequency and factors associated with the reproducibility of reporting circumcision status. STUDY DESIGN:Secondary analysis of data using logistic regression modeling...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200106000-00005
更新日期:2001-06-01 00:00:00
abstract:BACKGROUND:Denmark introduced the quadrivalent human papillomavirus vaccine into the vaccination program for 12- to 15-year-old girls in 2008 to 2009. In 2012, the program was supplemented with a catch-up program for women aged up to 27 years. We evaluated the effectiveness of the Danish vaccination program on the nati...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000418
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVES:A sharp increase in the incidence of gonorrhea has been observed in Tel Aviv, Israel, since 1999. Almost one half of interviewed patients admitted contracting the infection from a sex worker. In two thirds of the cases, oral sex (fellatio) was the most probable route of acquiring the disease. In the current ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000204675.92459.3c
更新日期:2006-08-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to assess the risk profile for chronic pelvic pain (CPP) after pelvic inflammatory disease (PID). STUDY:Multivariate logistic regression was used to assess risk factors for CPP in a longitudinal study of 780 predominately black, urban women with clinically suspected PID: compl...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000162361.69041.a5
更新日期:2005-05-01 00:00:00
abstract:OBJECTIVES/GOAL:We compared risk behaviors and HIV testing between recent (in the U.S. <5 years) and established (in the U.S. >5 years) Hispanic immigrant men (N = 410). STUDY:This study was a population-based, cross-sectional survey of HIV/sexually transmitted disease markers and risk behaviors in men age 18 to 35 ye...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000161185.06387.94
更新日期:2005-08-01 00:00:00