High-dose vaginal maintenance metronidazole for recurrent bacterial vaginosis: a pilot study.

abstract：BACKGROUND:A prophylactic quadrivalent human papillomavirus (HPV) vaccine could benefit adult women if they are susceptible to incident genital HPV infections and are acquiring new infections with vaccine HPV types to which they were previously not exposed. This report presents baseline and prospective data from a rand...

journal_title：Sexually transmitted diseases

authors： Velicer C,Zhu X,Vuocolo S,Liaw KL,Saah A

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Obstetric and gynecologic complications associated with bacterial vaginosis and trichomoniasis have heightened awareness of these conditions, and thus metronidazole's role in obstetric and gynecologic practice continues to increase. GOAL OF THIS STUDY:To review the clinical indications for metronidazole in ...

journal_title：Sexually transmitted diseases

authors： Schwebke JR

更新日期：1995-11-01 00:00:00

abstract：OBJECTIVES:To assess the efficacy of topical 80% trichloroacetic acid (TCA) to treat internal anal high-grade squamous intraepithelial lesions (HSILs) in HIV-positive individuals. METHODS:All patients who attended the University of Pittsburgh Anal Dysplasia Clinic for treatment of biopsy-proven internal anal HSIL with...

journal_title：Sexually transmitted diseases

authors： Cranston RD,Baker JR,Liu Y,Wang L,Elishaev E,Ho KS

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Lymphogranuloma venereum (LGV) has reestablished itself as an endemic sexually transmitted infection in the United Kingdom and elsewhere in Europe and North America over the last decade. Current guidelines suggest treatment with 21 days of doxycycline; however, the evidence base for LGV treatment including i...

journal_title：Sexually transmitted diseases

authors： Simons R,Candfield S,French P,White JA

更新日期：2018-06-01 00:00:00

abstract：:Ureaplasma urealyticum strains isolated from urethral specimens of 112 patients with nongonococcal urethritis, 17 with gonorrhea, and 33 asymptomatic carriers (controls) were tested by the growth-inhibition test with standard ureaplasma antisera (serotypes 1-8). Cases with more than one serotype (two to four types) we...

journal_title：Sexually transmitted diseases

authors： Crăcea E,Constantinescu S,Lazar M

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND:Calls for increased investment in sexually transmitted infection (STI) treatment across the developing world have been made to address the high disease burden and the association with HIV transmission. GOALS:The goals of this study were to systematically review evidence on the cost of treating curable STIs ...

journal_title：Sexually transmitted diseases

authors： Terris-Prestholt F,Vyas S,Kumaranayake L,Mayaud P,Watts C

更新日期：2006-10-01 00:00:00

abstract：:We described sexual transmission behaviors and serodiscordant partnerships among an online sample of HIV-positive men who have sex with men (N = 416) in Asia. High rates of unprotected anal intercourse (74.8%), serodiscordant partnerships (68.5%), and unprotected sex within serodiscordant partnerships (∼60.0%) were re...

journal_title：Sexually transmitted diseases

authors： Wei C,Guadamuz TE,Lim SH,Koe S

更新日期：2012-04-01 00:00:00

abstract：:Strains of Neisseria gonorrhoeae requiring arginine, hypoxanthine, and uracil (AHU) may cause disseminated gonococcal infection (DGI). A significant epidemiologic association was noted between the incidence of disseminated gonococcal infection and the presence of gonococci of the AHU auxotype in the community over a n...

journal_title：Sexually transmitted diseases

authors： Noble RC,Reyes RR,Parekh MC,Haley JV

更新日期：1984-04-01 00:00:00

abstract：:Cross-sectional surveys were conducted annually from 2006 to 2011 at a music festival. Eight thousand one hundred sixty-five young people completed surveys. STI testing rates increased over time, but there was an increase in the prevalence of some sexual risk behaviors and little improvement in STI knowledge between 2...

journal_title：Sexually transmitted diseases

authors： Lim MS,Bowring AL,Gold J,Aitken CK,Hellard ME

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Few studies have examined the association between self-reported sexual risk behaviors and biologic outcomes in human immunodeficiency virus (HIV)-1-seropositive African adults. METHODS:We conducted a prospective cohort study in 898 HIV-1-seropositive women who reported engaging in transactional sex in Momba...

journal_title：Sexually transmitted diseases

authors： McClelland RS,Richardson BA,Wanje GH,Graham SM,Mutunga E,Peshu N,Kiarie JN,Kurth AE,Jaoko W

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVES:Recent trial results demonstrate that the transmission probability of HSV-2 in monogamous couples is nearly halved by the use of valacyclovir as suppressive therapy. GOAL:The goal of this study is to understand the potential impact of suppressive valacyclovir therapy on the transmission of HSV-2 within a po...

journal_title：Sexually transmitted diseases

authors： Williams JR,Jordan JC,Davis EA,Garnett GP

更新日期：2007-03-01 00:00:00

abstract：:This report describes the cases of seven patients who had primary genital infection with herpes simplex virus and whose initial nontreponemal and treponemal tests for syphilis were nonreactive. On routine posttreatment examination, a change in the consistency of the ulcers was noticed, and the inguinal nodes, which ha...

journal_title：Sexually transmitted diseases

authors： Fiumara NJ,Schmidt-Ulrick B,Comite H

更新日期：1980-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Crack-smoking sexually transmitted disease (STD) patients are at high-risk for contracting HIV. GOAL OF THE STUDY:To examine the effects of cocaine use and other correlates on high-risk sexual behavior among STD clinic patients. STUDY DESIGN:This was a cross-sectional study of 1,490 consecut...

journal_title：Sexually transmitted diseases

authors： Hser YI,Chou CP,Hoffman V,Anglin MD

更新日期：1999-02-01 00:00:00

abstract：:We describe a case of acute urethritis caused by Neisseria meningitidis group B in a heterosexual man. The symptoms started five days after intercourse that included fellatio with a casual female partner. No other urethral pathogens could be isolated. After intramuscular administration of penicillin G, clinical signs ...

journal_title：Sexually transmitted diseases

authors： Hartmann AA,Elsner P

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:HerpeSelect HSV-1 and HSV-2 ELISAs are glycoprotein G-based, type-specific antibody detection tests that are approved by the US Food and Drug Administration for diagnosis of genital herpes. GOAL:The goal was to determine seroconversion times by means of HerpeSelect ELISAs. STUDY DESIGN:Four-hundred thirtee...

journal_title：Sexually transmitted diseases

authors： Ashley-Morrow R,Krantz E,Wald A

更新日期：2003-04-01 00:00:00

abstract：:We evaluated self-sampling to detect pharyngeal Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infection among men who have sex with men attending a San Francisco STD clinic. The prevalence of pharyngeal NG and CT infection was 6.7% (32/480) and 1.3% (6/480), respectively. The percent agreement between self...

journal_title：Sexually transmitted diseases

authors： Freeman AH,Bernstein KT,Kohn RP,Philip S,Rauch LM,Klausner JD

更新日期：2011-11-01 00:00:00

abstract：:Chlamydia trachomatis was present in cell cultures of specimens from 96 (32%) of 300 men with nongonococcal urethritis, but this organism was not isolated from 100 healthy volunteers matched for sex and age. The prevalence of serum antibodies to C. trachomatis was investigated with the use of a single-antigen, indirec...

journal_title：Sexually transmitted diseases

authors： Cevenini R,La Placa M

更新日期：1981-10-01 00:00:00

abstract：BACKGROUND:Standard counseling at nongonococcal urethritis (NGU) diagnosis includes advice to abstain from sex for at least 7 days and until symptoms resolve. METHODS:From December 2014 to July 2018, we enrolled men who have sex with men and received azithromycin (1 g) for NGU at the Public Health-Seattle and King Cou...

journal_title：Sexually transmitted diseases

authors： Chambers LC,Hughes JP,Glick SN,Morgan JL,Lowens MS,Robinson TS,Romano SS,Leipertz GL,Jensen JS,Khosropour CM,Fredricks DN,Golden MR,Manhart LE

更新日期：2019-10-01 00:00:00

abstract：:We describe the effects of multiple freeze and thaw cycles on the sensitivity of the immunoglobulins IgG and IgM measured by enzyme-linked immunoassays in the sera of patients with syphilis. Stored frozen sera can withstand repeated freezing and thawing cycles with a minimal detrimental effect on the sensitivity of th...

journal_title：Sexually transmitted diseases

authors： Castro AR,Jost HA

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVES:To describe the reliability of reported dates of first and last sexual exposure, as elicited from sexually transmitted disease/human immunodeficiency virus cases during routine contact investigation, and determine their adequacy for assessing concurrency. METHODS:We used contact tracing data from 5 studies ...

journal_title：Sexually transmitted diseases

authors： Brewer DD,Rothenberg RB,Muth SQ,Roberts JM Jr,Potterat JJ

更新日期：2006-05-01 00:00:00

abstract：:The effect of the susceptibility of Trichomonas vaginalis strains to metronidazole on response to treatment was determined from minimal inhibitory concentrations (MICs) for organisms isolated during a clinical trial in which single 1- and 2-g doses of metronidazole were compared. Fifty-seven strains were isolated from...

journal_title：Sexually transmitted diseases

authors： Ralph ED,Darwish R,Austin TW,Smith EA,Pattison FL

更新日期：1983-07-01 00:00:00

abstract：OBJECTIVES:Two of the major diagnostic methods for Trichomonas vaginalis, wet mount and culture, rely on the continued viability of the organism. Methods to increase the viability of T. vaginalis in urine are needed. GOAL:The goal of this study was to develop a method that increases the time of viability of T. vaginal...

journal_title：Sexually transmitted diseases

authors： Shafir SC,Sorvillo FJ,Upcroft JA,Upcroft P

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:The cerebrospinal fluid (CSF)-Venereal Disease Research Laboratory (VDRL) test is only 27% sensitive for diagnosing neurosyphilis. Discriminant analysis, used on 124 patients, shows that other commonly used laboratory tests can, in combination, identify 87% of patients with neurosyphilis with 94% specificity...

journal_title：Sexually transmitted diseases

authors： MacLean S,Luger A

更新日期：1996-09-01 00:00:00

abstract：:We used 2008-2009 physician and hospital charges to estimate the direct cost of medical care per case of pelvic inflammatory disease. The estimated average total charge per episode was $3,025 (SD: $4155). The estimated average charge for patients treated in ambulatory (outpatient clinic and emergency department) setti...

journal_title：Sexually transmitted diseases

authors： Trent M,Ellen JM,Frick KD

更新日期：2011-04-01 00:00:00

abstract：:Genetic detection of Neisseria gonorrhoeae is replacing culture for increased diagnostic sensitivity. Specificity of several nucleic acid amplification tests is suboptimal. Herein, the Gen-Probe APTIMA Combo 2 and APTIMA GC assays had 100% specificity and 100% sensitivity after confirmatory testing, when testing 298 i...

journal_title：Sexually transmitted diseases

authors： Golparian D,Tabrizi SN,Unemo M

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The Cuban Ministry of Public Health plans to implement the syndromic approach to sexually transmitted diseases in persons with urethral or vaginal syndrome in Cuba using 500 mg ciprofloxacin as therapy. Although the emergence of clinical isolates of Neisseria gonorrhoeae with decreased suscept...

journal_title：Sexually transmitted diseases

authors： Llanes R,Sosa J,Guzmán D,Gutiérrez Y,Llop A,Ricardo O

更新日期：2001-02-01 00:00:00

abstract：:Survey data from a university in the southeast United States were used to estimate the relation between sexual risk factors, perceived susceptibility, and human immunodeficiency virus testing intention among sexually active college students who had never been tested. Sexual risk factors, but not knowledge, were indire...

journal_title：Sexually transmitted diseases

authors： James TG,Cheong J,Ryan SJ

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Little is known about cytokine responses to syphilis infection in HIV-1-infected individuals. METHODS:We retrospectively identified patients with HIV-1 and Treponema pallidum coinfection. Plasma samples from before, during, and after coinfection were analyzed for interleukin (IL)-2, IL-4, IL-6, IL-8, IL-10,...

journal_title：Sexually transmitted diseases

authors： Knudsen A,Benfield T,Kofoed K

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:The ability to seek help or medical care for sexually transmitted infections (STIs) is vital for sexually active youth; yet, their needs are often unmet. METHODS:We conducted a qualitative systematic review of studies to assess youth and provider views about the behaviors of young people in help seeking and...

journal_title：Sexually transmitted diseases

authors： Newton-Levinson A,Leichliter JS,Chandra-Mouli V

更新日期：2017-06-01 00:00:00

abstract：:In light of the racial-ethnic and poverty composition of the United States population and the distribution of syphilis morbidity across population subgroups, it is important to determine how race-ethnicity and poverty jointly and independently affect transmission dynamics of syphilis and other sexually transmitted dis...

journal_title：Sexually transmitted diseases

authors： Aral SO

更新日期：1996-01-01 00:00:00