Metronidazole: utilization in the obstetric and gynecologic patient.

Abstract:

BACKGROUND:Obstetric and gynecologic complications associated with bacterial vaginosis and trichomoniasis have heightened awareness of these conditions, and thus metronidazole's role in obstetric and gynecologic practice continues to increase. GOAL OF THIS STUDY:To review the clinical indications for metronidazole in the obstetric and gynecologic setting, as well as the pharmacokinetics and potential adverse effects of the drug. STUDY DESIGN:Review of the current literature concerning metronidazole. RESULTS AND CONCLUSIONS:Metronidazole remains a valuable agent for the treatment of anaerobic and protozoal infections with little evidence of resistance. Although issues of mutagenicity and carcinogenicity remain theoretical concerns, current data do not support the existence of these risks in humans.

journal_name

Sex Transm Dis

authors

Schwebke JR

subject

Has Abstract

pub_date

1995-11-01 00:00:00

pages

370-6

issue

6

eissn

0148-5717

issn

1537-4521

journal_volume

22

pub_type

杂志文章,评审
  • Clustering of syringe sharing and unprotected sex risk behaviors in male injecting drug users in China.

    abstract:OBJECTIVES:To investigate, among male injecting drug users (IDU), the relationships between higher risk IDU-related and sex-related behaviors. GOAL:To highlight the clustering effects of the 2 forms of risk behaviors. STUDY DESIGN:Behavioral surveillance surveys conducted in Sichuan were analyzed (n = 3105). RESULTS...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/01.olq.0000253339.49181.f9

    authors: Lau JT,Cheng F,Tsui HY,Zhang Y,Zhang J,Wang N,Zhang L

    更新日期:2007-08-01 00:00:00

  • Vaginal swabs are the optimal specimen for detection of genital Chlamydia trachomatis or Neisseria gonorrhoeae using the Cobas 4800 CT/NG test.

    abstract::Performance characteristics of the Cobas 4800 CT/NG assay were estimated for vaginal swab samples from more than 4000 women. Vaginal samples identified 92.9% and 98.5% of Chlamydia and Gonorrhea infections, respectively, which was more than any other single specimen type (endocervical swabs or urine) regardless of col...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1097/OLQ.0b013e3182717833

    authors: Van Der Pol B,Taylor SN,Liesenfeld O,Williams JA,Hook EW 3rd

    更新日期:2013-03-01 00:00:00

  • Developing a predictive model to prioritize human immunodeficiency virus partner notification in North Carolina.

    abstract:BACKGROUND:Disease intervention specialists (DIS) in North Carolina have less time to conduct partner notification because of competing responsibilities while simultaneously facing increased case loads because of increased human immunodeficiency virus (HIV) testing. We developed a model to predict undiagnosed HIV infec...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e318239da4e

    authors: Hoots BE,MacDonald PD,Hightow-Weidman LB,Leone PA,Miller WC

    更新日期:2012-01-01 00:00:00

  • Sex and disease. Playing the odds in the 1990s.

    abstract::Selected results from a recent study on sexual behavior in the United States are presented, focusing on the association between sexual behavior, disease prevention, and STD outcome. The data are from national household samples of adult men and women. The results show that a sizeable proportion of the U.S. adult popula...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:

    authors: Tanfer K

    更新日期:1994-03-01 00:00:00

  • Does a choice of condoms impact sexually transmitted infection incidence? A randomized, controlled trial.

    abstract:OBJECTIVE:The objective of this study was to assess whether providing a choice of condoms would increase condom acceptability, increase self-reported use, and decrease incident sexually transmitted infection. STUDY:We randomized 414 men presenting with urethral discharge in Jamaica to receive either the "standard" cli...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/01.olq.0000187200.07639.c6

    authors: Steiner MJ,Hylton-Kong T,Figueroa JP,Hobbs MM,Behets F,Smikle M,Tweedy K,Powell S,McNeil L,Brathwaite A

    更新日期:2006-01-01 00:00:00

  • A Pilot Study to Increase the Efficiency of HIV Outreach Testing Through the Use of Timely and Geolocated HIV Viral Load Surveillance Data.

    abstract:BACKGROUND:Eliminating HIV transmission in a population necessitates identifying population reservoirs of HIV infection and subgroups most likely to transmit. HIV viral load is the single most important predictor of HIV transmission. The objective of this analysis was to evaluate whether a public health practice pilot ...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0000000000000730

    authors: Jennings JM,Schumacher C,Perin J,Myers T,Fields N,Greiner Safi A,Chaulk P

    更新日期:2018-03-01 00:00:00

  • Estimating the Total Annual Direct Cost of Providing Sexually Transmitted Infection and HIV Testing and Counseling for Men Who Have Sex With Men in the United States.

    abstract:BACKGROUND:The Centers for Disease Control and Prevention recommends annual sexually transmitted infection (STI) and HIV testing and counseling for men who have sex with men (MSM) in the United States. We estimated the annual total direct medical cost of providing recommended STI and HIV testing and counseling services...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0000000000000341

    authors: Owusu-Edusei K Jr,Gift TL,Patton ME,Johnson DB,Valentine JA

    更新日期:2015-10-01 00:00:00

  • Notification for sexually transmitted infections and HIV among sex workers in Guatemala: acceptability, barriers, and preferences.

    abstract::Partner notification for HIV and other sexually transmitted infections is acceptable and feasible among female sex workers attending sexually transmitted infection clinics in Guatemala, especially for regular partners. Intention to refer the sexual partner was best predicted by attitude followed by social norms and ba...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e31824f8b1b

    authors: Sabidó M,Gregg LP,Vallès X,Nikiforov M,Monzón JE,Pedroza MI,Vermund SH,Casabona J

    更新日期:2012-07-01 00:00:00

  • Factors associated with herpes simplex virus type 2 incidence in a cohort of human immunodeficiency virus type 1-seronegative Kenyan men and women reporting high-risk sexual behavior.

    abstract:BACKGROUND:Herpes simplex virus type 2 (HSV-2) is an important cause of genital ulcers and can increase the risk for human immunodeficiency virus type 1 (HIV-1) transmission. Our objective was to determine the incidence and correlates of HSV-2 infection in HIV-1-seronegative Kenyan men reporting high-risk sexual behavi...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e31821a6225

    authors: Okuku HS,Sanders EJ,Nyiro J,Ngetsa C,Ohuma E,McClelland RS,Price MA,Graham SM

    更新日期:2011-09-01 00:00:00

  • Lack of evidence for intertypic recombinants in the pathogenesis of recurrent genital infections with herpes simplex virus type 1.

    abstract::Clinical observations indicate that herpes simplex virus type 1 (HSV-1) is significantly less likely than herpes simplex virus type 2 (HSV-2) to establish latency in (or reactivate from) sacral ganglionic tissue. In an effort to identify viral functions associated with latency, we analyzed HSV-1 isolates from three pa...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-198607000-00005

    authors: Fife KH,Boggs D

    更新日期:1986-07-01 00:00:00

  • Confirmation of the Syva MicroTrak enzyme immunoassay for chlamydia trachomatis by Syva Direct Fluorescent Antibody Test.

    abstract:BACKGROUND AND OBJECTIVES:The Syva Micro Trak enzyme immunoassay (EIA) is used widely for screening women infected with Chlamydia trachomatis. Confirmatory tests used in conjunction with EIA screening have shown that false-positive results are common. GOALS:To evaluate the specificity of the Syva MicroTrak EIA by conf...

    journal_title:Sexually transmitted diseases

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00007435-199611000-00005

    authors: Beebe JL,Masters H,Jungkind D,Heltzel DM,Weinberg A

    更新日期:1996-11-01 00:00:00

  • Selecting an HIV Test: A Narrative Review for Clinicians and Researchers.

    abstract::Given the many options available, selecting an HIV test for a particular clinical or research setting can be daunting. Making an informed decision requires an assessment of the likelihood of acute infection in the test population and an understanding of key aspects of the tests themselves. The ability of individual te...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章,评审

    doi:10.1097/OLQ.0000000000000719

    authors: Hurt CB,Nelson JAE,Hightow-Weidman LB,Miller WC

    更新日期:2017-12-01 00:00:00

  • Gonococcal endocarditis.

    abstract::Three cases of endocarditis caused by Neisseria gonorrhoeae involving the aortic, mitral an tricuspid valves are reported. Two cases in young women, following syndromes suggestive of gonococcal arthritis, presented as acute endocarditis and were fatal. The male patient experienced a subacute course, and the diagnosis ...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-197707000-00002

    authors: John JF Jr,Nichols JT,Eisenhower EA,Farrar WE Jr

    更新日期:1977-07-01 00:00:00

  • Opt-out screening for Chlamydia trachomatis and Neisseria gonorrhoeae in female detainees at Cook County jail in Chicago, IL.

    abstract:BACKGROUND:In April of 2011, the Cook County Jail initiated opt-out screening of all women for Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (GC) at the time of intake. In this retrospective review, we assess the impact of opt-out protocol on rates of testing, diagnoses, and successful treatment. METHODS:We col...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0000000000000106

    authors: Cole J,Hotton A,Zawitz C,Kessler H

    更新日期:2014-03-01 00:00:00

  • Chlamydia prevalence among college students: reproductive and public health implications.

    abstract:BACKGROUND:Routine chlamydia screening is not readily available at all college campuses. OBJECTIVES:: To assess the prevalence of Chlamydia trachomatis among asymptomatic college students and to compare chlamydia positivity by selected demographic variables. METHODS:Analysis of demographical data collected on 789 stu...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e3181676697

    authors: James AB,Simpson TY,Chamberlain WA

    更新日期:2008-06-01 00:00:00

  • Seroprevalence of human immunodeficiency virus type I (HIV-1) antibodies in a family-planning population.

    abstract::Blind testing of 743 women who attended an inner-city hospital family-planning clinic showed 8 (1.1%) patients to have serum antibodies to human immunodeficiency virus type I (HIV-1). A retrospective chart survey did not show an association between HIV-1 antibody seropositivity and ethnicity, marital status, education...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-199107000-00003

    authors: Spence MR,Robbins SM,Polansky M,Schable CA

    更新日期:1991-07-01 00:00:00

  • Efficacy of a booster counseling session 6 months after HIV testing and counseling: a randomized, controlled trial (RESPECT-2).

    abstract:BACKGROUND:HIV counseling prevents sexually transmitted diseases (STDs), with most of the benefit accumulating in the first 6 months. STUDY:The authors conducted a multicenter, randomized, controlled trial of a 20-minute additional (booster) counseling session 6 months after HIV counseling compared with no additional ...

    journal_title:Sexually transmitted diseases

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1097/01.olq.0000151420.92624.c0

    authors: Metcalf CA,Malotte CK,Douglas JM Jr,Paul SM,Dillon BA,Cross H,Brookes LC,Deaugustine N,Lindsey CA,Byers RH,Peterman TA,RESPECT-2 Study Group.

    更新日期:2005-02-01 00:00:00

  • Effects of screening and partner notification on Chlamydia positivity in the United States: a modeling study.

    abstract:OBJECTIVES:Model impact of increasing screening and partner notification (PN) on chlamydia positivity. METHODS:We used a stochastic simulation model describing pair formation and dissolution in an age-structured heterosexual population. The model accounts for steady, casual, and concurrent partnerships and a highly se...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e31824e52c2

    authors: Kretzschmar M,Satterwhite C,Leichliter J,Berman S

    更新日期:2012-05-01 00:00:00

  • High-frequency of quinolone-resistant Neisseria gonorrhoeae in Austria with a common pattern of triple mutations in GyrA and ParC genes.

    abstract:OBJECTIVE:Quinolones have a broad spectrum of antimicrobial activity and are widely used for the treatment of uncomplicated Neisseria gonorrhoeae infections. A dramatic increase in the number of reported N. gonorrhoeae infections as well as quinolone-resistant isolates in Vienna prompted us to investigate the pattern o...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/01.olq.0000140019.18390.28

    authors: Uthman A,Heller-Vitouch C,Stary A,Bilina A,Kuchinka-Koch A,Söltz-Szöts J,Tschachler E

    更新日期:2004-10-01 00:00:00

  • The costs of treating curable sexually transmitted infections in low- and middle-income countries: a systematic review.

    abstract:BACKGROUND:Calls for increased investment in sexually transmitted infection (STI) treatment across the developing world have been made to address the high disease burden and the association with HIV transmission. GOALS:The goals of this study were to systematically review evidence on the cost of treating curable STIs ...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章,评审

    doi:10.1097/01.olq.0000235177.30718.84

    authors: Terris-Prestholt F,Vyas S,Kumaranayake L,Mayaud P,Watts C

    更新日期:2006-10-01 00:00:00

  • Podophyllotoxin in serum: absorption subsequent to three-day repeated applications of a 0.5% ethanolic preparation on condylomata acuminata.

    abstract::High-performance liquid chromatography was used for quantitative determination of podophyllotoxin in serum subsequent to repeated applications of a 0.5% ethanolic preparation on condylomata acuminata. The drug was not detectable in the serum of ten men treated with < or = 50 microliters. In serum of seven patients rec...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:

    authors: von Krogh G

    更新日期:1982-01-01 00:00:00

  • Evaluation of 4 Algorithms to Identify Incident Syphilis Among HIV-Positive Men Who Have Sex With Men Engaged in Primary Care.

    abstract::We developed 4 algorithms for syphilis among HIV-positive men who have sex with men who engaged in primary care in 2016 to 2017. Clinician-based diagnosis from chart reviews was the gold standard. Sensitivities ranged from 74.2% to 93.9%. Specificities were greater than 99% with positive and negative predictive values...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0000000000000938

    authors: Menza TW,Levine K,Grasso C,Mayer K

    更新日期:2019-04-01 00:00:00

  • Human immunodeficiency virus type 1 among bar and hotel workers in northern Tanzania: the role of alcohol, sexual behavior, and herpes simplex virus type 2.

    abstract:GOALS:We assessed baseline prevalence of human immunodeficiency virus type 1 (HIV-1) and other STDs, as well as behavioral and biologic risk factors for HIV-1 in a population of female bar/hotel workers in Moshi, Tanzania. STUDY DESIGN:Between 2002 and 2003, we enrolled 1042 female bar/hotel workers in an ongoing pros...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/01.olq.0000187204.57006.b3

    authors: Ao TT,Sam NE,Masenga EJ,Seage GR 3rd,Kapiga SH

    更新日期:2006-03-01 00:00:00

  • Chlamydia, Gonorrhea, and Human Immunodeficiency Virus Infection Among Transgender Women and Transgender Men Attending Clinics that Provide Sexually Transmitted Disease Services in Six US Cities: Results From the Sexually Transmitted Disease Surveillance

    abstract:BACKGROUND:Transgender women and transgender men are disproportionately affected by human immunodeficiency virus (HIV) infection and may be vulnerable to other sexually transmitted diseases (STDs), but the lack of surveillance data inclusive of gender identity hinders prevention and intervention strategies. METHODS:We...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0000000000000917

    authors: Pitasi MA,Kerani RP,Kohn R,Murphy RD,Pathela P,Schumacher CM,Tabidze I,Llata E

    更新日期:2019-02-01 00:00:00

  • Predictors of condom use among patients with sexually transmitted diseases in Uganda.

    abstract:BACKGROUND AND OBJECTIVE:Patients with sexually transmitted diseases (STDs) are at an increased risk of HIV infection and they must be targeted for increased condom use. GOAL:To identify predictors of condom use among patients with STDs. STUDY DESIGN:In a cross-sectional survey, an interview-administered questionnair...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-199910000-00001

    authors: Nuwaha F,Faxelid E,Höjer B

    更新日期:1999-10-01 00:00:00

  • HIV postexposure prophylaxis use among Ontario female adolescent sexual assault victims: a prospective analysis.

    abstract:BACKGROUND:This study examined the use of HIV postexposure prophylaxis (PEP) among sexually assaulted adolescent females. METHODS:We analyzed data from the HIV PEP Project, an implementation and evaluation of a program of universal offering of PEP to sexual assault victims of all ages. Baseline and follow-up data were...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/OLQ.0b013e3181824f3c

    authors: Du Mont J,Myhr TL,Husson H,Macdonald S,Rachlis A,Loutfy MR

    更新日期:2008-12-01 00:00:00

  • Time course of seroconversion by HerpeSelect ELISA after acquisition of genital herpes simplex virus type 1 (HSV-1) or HSV-2.

    abstract:BACKGROUND:HerpeSelect HSV-1 and HSV-2 ELISAs are glycoprotein G-based, type-specific antibody detection tests that are approved by the US Food and Drug Administration for diagnosis of genital herpes. GOAL:The goal was to determine seroconversion times by means of HerpeSelect ELISAs. STUDY DESIGN:Four-hundred thirtee...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-200304000-00007

    authors: Ashley-Morrow R,Krantz E,Wald A

    更新日期:2003-04-01 00:00:00

  • Prevalence and risk factors for herpes simplex virus type 2 antibodies among low- and high-risk populations in Indonesia.

    abstract:OBJECTIVES/GOAL:Data on prevalence of herpes simplex virus type 2 (HSV-2) infections are limited in Asia. This study investigated the seroprevalence of, and risk factors for, antibodies to HSV-2 among low- and high-risk, predominantly asymptomatic populations in Indonesia. STUDY DESIGN:We screened women attending mate...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/01.olq.0000230427.01727.80

    authors: Davies SC,Taylor JA,Sedyaningsih-Mamahit ER,Gunawan S,Cunningham AL,Mindel A

    更新日期:2007-03-01 00:00:00

  • Patterns and predictors of female condom use among ethnically diverse women attending family planning clinics.

    abstract:BACKGROUND:The female condom is a viable option for women to protect themselves from HIV infection and other sexually transmitted diseases. GOAL:The goal was to examine the level of female condom use and factors associated with frequency of use among US women living in San Francisco and Oakland, California. STUDY DES...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/00007435-200301000-00018

    authors: Choi KH,Gregorich SE,Anderson K,Grinstead O,Gómez CA

    更新日期:2003-01-01 00:00:00

  • Sexually transmitted diseases and risk behaviors among pregnant women attending inner city public sexually transmitted diseases clinics in Baltimore, MD, 1996-2002.

    abstract:OBJECTIVE:To determine the prevalence of sexually transmitted diseases (STDs) and characterize behavioral correlates among pregnant women attending inner city public STD clinics. STUDY DESIGN:A retrospective study of 2303 pregnant women frequency matched by clinic and year of visit to 2303 nonpregnant women seeking se...

    journal_title:Sexually transmitted diseases

    pub_type: 杂志文章

    doi:10.1097/olq.0b013e31812e6b9a

    authors: Johnson HL,Erbelding EJ,Zenilman JM,Ghanem KG

    更新日期:2007-12-01 00:00:00