Abstract:
:The mechanism of inhibition of Neisseria gonorrhoeae by pyocin 103 was examined. Pyocin 103 decreases the viability of N. gonorrhoeae immediately after its addition to logarithmically growing cells by single-hit kinetics. This inhibition was paralleled by an immediate cessation of protein synthesis, RNA synthesis, and active transport. From the data presented, it is likely that pyocin kills N. gonorrhoeae in the same manner that it kills Pseudomonas aeruginosa, i.e., by interfering with energy metabolism.
journal_name
Sex Transm Disjournal_title
Sexually transmitted diseasesauthors
Stein DC,Clark VL,Young FEdoi
10.1097/00007435-198301000-00002subject
Has Abstractpub_date
1983-01-01 00:00:00pages
7-13issue
1eissn
0148-5717issn
1537-4521journal_volume
10pub_type
杂志文章abstract:BACKGROUND:Human immunodeficiency virus (HIV)/sexually transmitted disease (STD)-related interventions rely on self-reported risk behavioral data, which are biased toward social desirability. It is warranted to develop methods for data triangulation. METHODS:Some questions on HIV/STD-related behaviors that were asked ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e318218cc66
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVES:To evaluate opportunities for earlier human immunodeficiency virus (HIV) diagnosis within a comprehensive public health care system. STUDY DESIGN:Retrospective review of newly diagnosed HIV-infected patients between September 2001 and December 2003. RESULTS:One hundred twenty of 348 (34%) newly diagnosed H...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000194617.91454.3f
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:People with multiple sex partners forget a significant proportion of their partners, and drug injectors forget a large proportion of the persons with whom they inject drugs. This incomplete reporting poses a problem for partner notification and social network research on infectious disease. GOAL:To evaluate...
journal_title:Sexually transmitted diseases
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00007435-200111000-00010
更新日期:2001-11-01 00:00:00
abstract:BACKGROUND:Studies of alcohol use and sexual behavior in African populations have primarily been cross-sectional, used nonvalidated measures of alcohol use, or relied on self-reported sexual risk endpoints. Few have focused on human immunodeficiency virus (HIV)-positive women. METHODS:Longitudinal data were collected ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000502
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:Herpes simplex virus-2, the most common cause of genital ulcer disease (GUD) globally, is a cofactor in human immunodeficiency virus type-1 (HIV-1) acquisition and transmission. Current World Health Organization guidelines for sexually transmitted infections recommend acyclovir as first-line syndromic treatm...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e3181e212e5
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND:Since the early 1980s, the Bahamas has experienced sequential epidemics of freebase/crack cocaine use, genital ulcer-inguinal adenopathy disease (GUD), and heterosexual HIV infection. GOAL:To prospectively define the etiology of GUD in patients at the Princess Margaret Hospital during outbreaks of crack coc...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200205000-00001
更新日期:2002-05-01 00:00:00
abstract::Culture of urethral specimens from a 21-year-old man with nongonococcal urethritis yielded both Chlamydia trachomatis and a minocycline-resistant strain of Ureaplasma urealyticum. In such situations, the causal agent of the urethritis is frequently considered to be C. trachomatis. However, the etiology of this case wa...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:
更新日期:1983-07-01 00:00:00
abstract::Mycoplasma hominis is isolated from the cervix of 10-20% of healthy, fertile women. In contrast, the organism is recovered from the lower genital tract of 50-70% of women with pelvic inflammatory disease. Moreover, a significant antibody response to M. hominis is found in one-fourth of all patients with clinical and/o...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:
更新日期:1983-10-01 00:00:00
abstract::An HIV-infected male patient who had sex with men and with a penicillin allergy presented with liver dysfunction due to secondary syphilis and was successfully treated with doxycycline. This case highlights that syphilitic hepatitis may be overlooked in this particular population, and health care providers should be a...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,评审
doi:10.1097/OLQ.0000000000000143
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND:Douching may interfere with determination of microbicide safety and effectiveness. This practice has not been adequately studied among women at risk of HIV infection. GOAL:This study assessed douching practices among women at risk of HIV infection in the United States. STUDY DESIGN:Data were collected on d...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200207000-00008
更新日期:2002-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Small ethnographic and clinic-based studies indicate that crack-smoking sex workers are at high risk for human immunodeficiency virus (HIV) and sexually transmitted diseases (STD). STUDY GOALS:To examine the prevalence of risky sexual behaviors and HIV and STD in a large sample of street-recr...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199804000-00002
更新日期:1998-04-01 00:00:00
abstract:OBJECTIVE:To compare self-reported doxycycline compliance in men and women attending an STD clinic with indications for Chlamydia trachomatis treatment to compliance measured using microprocessor-containing medication vials to count each time and date medication vials were opened. A secondary objective was to correlate...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199905000-00006
更新日期:1999-05-01 00:00:00
abstract:OBJECTIVES:We conducted formative research to evaluate the acceptability and feasibility of continuous diaphragm use among low-income women highly exposed to sexually transmitted infections (STIs) in Madagascar. GOAL:To identify potential obstacles to researching the effectiveness of diaphragm use for STI prevention i...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e31815abaa2
更新日期:2008-03-01 00:00:00
abstract:BACKGROUND:Adherence to recommended laboratory testing practices is crucial for sexually transmitted infection (STI) prevention and control. The objective of this paper is to compare Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) testing practices of US clinical laboratories in 2013 prior to the updated 2014...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000001299
更新日期:2020-09-18 00:00:00
abstract:BACKGROUND:Clinical studies demonstrate increased prevalence of human papillomavirus (HPV)-associated disease in HIV-infected individuals and an increased risk of HIV acquisition in HPV-infected individuals. The mechanisms underlying this synergy are not defined. We hypothesize that women with cervical intraepithelial ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e318255aeef
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:Hepatitis C virus (HCV) is a major global problem, transmitted primarily by percutaneous exposure to contaminated blood. GOAL:The goal of the study was to determine the seroprevalence of and risk factors for HCV among patients attending two urban STD clinics in Alberta. STUDY DESIGN:Anonymous unlinked sero...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200301000-00008
更新日期:2003-01-01 00:00:00
abstract::Strains of Trichomonas vaginalis were evaluated for their in vitro responses to metronidazole. A serial twofold dilution method that measured minimal inhibitory concentrations (MICs) by cessation of trophozoite motility was compared with the disk broth method, in which both cessation of motility and inhibition of trop...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198007000-00005
更新日期:1980-07-01 00:00:00
abstract:BACKGROUND:From an sexually transmitted disease (STD) intervention perspective, developing a practical way to identify persons in core transmitter groups has been difficult. However, persons who have repeated STD infections may be in such groups. GOAL:To evaluate a self-administered risk assessment approach that would...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200007000-00008
更新日期:2000-07-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to provide updated estimates of the average lifetime medical cost per infection for chlamydia, gonorrhea, and trichomoniasis. METHODS:We adapted a published decision tree model that allowed for 7 possible outcomes of infection: (1) symptomatic infection, treated, no sequelae; (...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000001357
更新日期:2021-01-23 00:00:00
abstract:OBJECTIVE:To evaluate the outcomes of a partner referral program at the sexually transmitted disease (STD) clinic in Amsterdam that encourages gonorrhea and chlamydia patients to refer their own partners to medical examination. STUDY DESIGN:355 patients with a confirmed infection cooperated in partner referral and gav...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199707000-00005
更新日期:1997-07-01 00:00:00
abstract:BACKGROUND:Sexually transmitted infections spread through a network of contacts created by the formation of sexual partnerships. In physics, networks have been characterized as "scale-free" if they follow a power law with an exponent between 2 and 3. OBJECTIVE:The objective of this study was to test statistically whet...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200406000-00012
更新日期:2004-06-01 00:00:00
abstract:BACKGROUND:Up to 50% of women with nonoptimal vaginal microbial community state type (CST) have bacterial vaginosis (BV). Little is known about what distinguishes women with and without BV diagnosis within nonoptimal CST. We identified features of women and their male sex partners associated with BV among women with no...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000001259
更新日期:2020-12-01 00:00:00
abstract::Identifying pathogen-specific signs or symptoms of nongonococcal urethritis could improve syndromic management accuracy. We evaluated nongonococcal urethritis signs and symptoms in 220 men with single-pathogen infections (Chlamydia trachomatis, Mycoplasma genitalium, Trichomonas vaginalis, or Ureaplasma urealyticum) o...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000001158
更新日期:2020-05-01 00:00:00
abstract::We conducted a simulation study to illustrate that P values can suggest but not confirm statistical significance; and they may not indicate epidemiological significance (importance). We recommend that researchers consider reporting effect sizes as P values in conjunction with confidence intervals or point estimates wi...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000635
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Surveillance for sexually transmitted diseases (STD) is important for priority setting, service development, and evaluating interventions. GOAL:To conduct health facility-based surveillance for STDs to inform design of a control program and to provide baseline measures for evaluation of interv...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199801000-00005
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVES:To evaluate the incidence of early syphilis based on time from initiation of highly active antiretroviral therapy (HAART) in human immunodeficiency virus (HIV)-infected patients. STUDY DESIGN:Five hundred thirty-nine HIV-positive patients undergoing HAART were followed up to 4 years to identify early (prima...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e31815b0148
更新日期:2008-03-01 00:00:00
abstract:BACKGROUND:Although the role of concurrent sexual partnerships (i.e., having sexual activity with another partner after a current partnership has been established) has been most strongly associated with the transmission of bacterial sexually transmitted infections, its role in the transmission of viral sexually transmi...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e3181bcd3e7
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to describe acceptability of urine chlamydia testing among asymptomatic men and providers' attitudes toward testing. STUDY DESIGN:Asymptomatic men (no urethral discharge/dysuria) were offered free testing and characteristics of men who accepted were compared with those who dec...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,多中心研究
doi:10.1097/01.olq.0000230438.12636.eb
更新日期:2007-03-01 00:00:00
abstract::A 46-year-old woman developed a febrile illness characterized by supraclavicular and inguinal lymphadopathy. The diagnosis of lymphogranuloma venereum was made by a fourfold rise in complement fixing antibody titer. Treatment with tetracycline was successful. Lymphogranuloma venereum can yield protean manifestations, ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-197701000-00004
更新日期:1977-01-01 00:00:00
abstract::Stool specimens from 89 high-risk, sexually active homosexual men were screened for enteric protozoal cysts. Patients whose specimens contained nonpathogenic cysts were investigated further by examination of fresh purged specimens. A total of 27 of the initial specimens (30%) contained protozoal cysts. Twenty-three pa...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-197810000-00008
更新日期:1978-10-01 00:00:00