Abstract:
OBJECTIVES:We conducted formative research to evaluate the acceptability and feasibility of continuous diaphragm use among low-income women highly exposed to sexually transmitted infections (STIs) in Madagascar. GOAL:To identify potential obstacles to researching the effectiveness of diaphragm use for STI prevention in a randomized controlled trial. STUDY DESIGN:Mixed methods to collect complex information. In a quantitative pilot study, women were asked to use diaphragms continuously (removing once daily for cleaning) for 8 weeks and promote consistent male condom use; they were interviewed and examined clinically during follow-up. Focus group discussions (FGDs) were conducted pre-/postpilot study. Audiotaped FGDs were transcribed, translated, coded, and analyzed. RESULTS:Ninety-three women participated in prepilot FGDs, 91 in the pilot study, and 82 in postpilot FGDs. Diaphragm use was acceptable and feasible, but participants reported lower condom use in FGDs than during interviews. Most participants reported in interviews that they used their diaphragms continuously, but FGDs revealed that extensive intravaginal hygiene practices may impede effective continuous diaphragm use. Despite counseling by study staff, FGDs revealed that participants believed the diaphragm provided effective protection against STIs and pregnancy. CONCLUSIONS:Mixed methods formative research generated information that the prospective pilot study alone could not provide and revealed contradictory findings. Results have methodological and ethical implications that affect trial design including provision of free hormonal contraceptives, and additional instructions for vaginal hygiene to avoid displacing the diaphragm. Mixed methods formative research should be encouraged to promote evidence-based study design and implementation.
journal_name
Sex Transm Disjournal_title
Sexually transmitted diseasesauthors
Behets FM,Van Damme K,Turner AN,Rabenja NL,Ravelomanana NL,Raharinivo MS,Zeller KA,Rennie SM,Swezey TAdoi
10.1097/OLQ.0b013e31815abaa2subject
Has Abstractpub_date
2008-03-01 00:00:00pages
238-42issue
3eissn
0148-5717issn
1537-4521journal_volume
35pub_type
杂志文章abstract:BACKGROUND:Trichomoniasis is associated with adverse pregnancy outcomes and increased risk for human immunodeficiency virus. Males are usually asymptomatic, and thus there is heavy reliance on partner notification for identifying infected male partners. The usual approach is partner referral but it is estimated that on...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,随机对照试验
doi:10.1097/OLQ.0b013e3181dd1691
更新日期:2010-06-01 00:00:00
abstract::A simple procedure that permits the rapid identification of clinical isolates of herpes simplex virus (HSV, type 1 or type 2) on the basis of stable and type-specific differences in the EcoRI restriction endonuclease patterns of the HSV-1 and HSV-2 genomes was tested for reliability. Complete concordance was first obt...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198404000-00007
更新日期:1984-04-01 00:00:00
abstract:BACKGROUND:In response to the increased hepatitis C virus (HCV) prevalence recently found among participants of the Amsterdam preexposure prophylaxis demonstration project, we evaluated HCV prevalence over time and the performance of the HCV-MOSAIC risk score for detection of HCV infection in HIV-negative men who have ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000877
更新日期:2018-12-01 00:00:00
abstract:OBJECTIVE:The impact of length of enrollment in a health plan on eligibility of women under the Healthcare Effectiveness Data and Information Set (HEDIS) chlamydia screening measure is not fully understood. We assessed the representativeness of the measure among the proportion of women aged 15 to 24 years with a gap in...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000338
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:The purpose of this review is to highlight selected studies in the economics literature that address sexually transmitted disease (STD)-related topics that are typically not examined in the STD literature. METHODS:Two databases (EconLit and Web of Science) were searched to locate STD-related articles in the...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,评审
doi:10.1097/OLQ.0b013e3182389a11
更新日期:2012-03-01 00:00:00
abstract::The accuracy of the routine Papanicolaou (Pap) smear in diagnosis of Chlamydia trachomatis infection of the cervix has stimulated controversial reports over the years. In the present study Pap smears from 100 women, evenly divided between culture-positive and culture-negative for C. trachomatis, who had been seen in a...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198901000-00003
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND & OBJECTIVES:To describe partner notification practices for chlamydial infections among private sector clinicians. STUDY DESIGN:Telephone interviews of clinicians and patients identified through public health case reports in Seattle-King County, August-October 1998. RESULTS:Clinicians reported advising 135...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199910000-00011
更新日期:1999-10-01 00:00:00
abstract:BACKGROUND:To study the incidence, persistence, and determinants of human papillomavirus (HPV) infection in a population of Inuit women from Nunavik, Quebec, by overall HPV infection, Alphapapillomavirus (α) species, and oncogenic risk grouping. METHODS:We recruited a cohort of Inuit women living in communities in Nun...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000272
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Neurocognitive impairment is common in human immunodeficiency virus (HIV)-infected subjects. The relationship of sexually transmitted diseases to neurocognitive changes is unknown. GOAL:To establish whether HIV-infected patients with a history of syphilis or gonorrhea have a higher rate of ne...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199708000-00003
更新日期:1997-08-01 00:00:00
abstract::Strains of Neisseria gonorrhoeae requiring arginine, hypoxanthine, and uracil (AHU) may cause disseminated gonococcal infection (DGI). A significant epidemiologic association was noted between the incidence of disseminated gonococcal infection and the presence of gonococci of the AHU auxotype in the community over a n...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198404000-00003
更新日期:1984-04-01 00:00:00
abstract::To define the performance characteristics of two newer tests for Trichomonas vaginalis (TV), the authors compared direct fluorescent antibody (DFA) (mixed monoclonal antibody, Integrated Diagnostics, Inc, Berkeley, CA) and acridine orange (AO) tests to standard wet mount (WM) preparations and culture (modified Diamond...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198907000-00002
更新日期:1989-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Few studies have demonstrated that bacterial vaginosis (BV) is associated with sexual behavior risk factors similar to those for other sexually transmitted diseases. The objective of this study was to determine the prevalence of these factors in a multivariate analysis of data from women infec...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199705000-00001
更新日期:1997-05-01 00:00:00
abstract::We described the ASiManager-AT digital flocculation reader to demonstrate concordance between visual and digital readings of the rapid plasma reagin test for detection of antibodies in the serum of patients with syphilis. A qualitative and quantitative rapid plasma reagin was performed on each serum samples giving a c...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e3182389ab9
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:The modes of transmission of HHV-8 are still unclear. GOAL:To evaluate the distribution and transmission of HHV-8 infection. DESIGN:Serosurvey conducted in a Cameroon hospital among 292 persons, including children (5-10 years), adolescents (15-20 years), and adults (30-40 years). Antibodies against lytic a...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200003000-00008
更新日期:2000-03-01 00:00:00
abstract:BACKGROUND:The burden of sexually transmitted infections (STIs) in areas of sub-Saharan Africa with poor access to health care services is not well documented. In remote areas of South Africa, we investigated the prevalence of STIs and approaches to providing STI services through a mobile clinic. METHODS:We recruited ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000931
更新日期:2019-03-01 00:00:00
abstract::Three different brief intervention programs to promote condom use were tested among patients in inner-city sexually transmitted disease (STD) clinics. The first, "Condom Skills," focused on teaching mechanical aspects of how to use a condom. The second, "Social Influences," emphasized how to negotiate condom use with ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199209000-00002
更新日期:1992-09-01 00:00:00
abstract:BACKGROUND:Little is known about sex practices that increase the risk of contracting HIV infection or the level of HIV and AIDS knowledge among sexually transmitted disease (STD) patients in China. OBJECTIVE:To describe AIDS and HIV knowledge, sexual practices, and factors associated with never using condoms among pat...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200103000-00009
更新日期:2001-03-01 00:00:00
abstract::In every society, congenital syphilis (CS) has significant medical, economic, societal and emotional burdens; these are poorly characterized but high. Inexplicably, the elimination of CS has failed to attract international attention. Yet, the cornerstones of programs to do this universally are in place, the recent dev...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,评审
doi:10.1097/01.olq.0000261456.09797.1b
更新日期:2007-07-01 00:00:00
abstract:OBJECTIVES:Recent trial results demonstrate that the transmission probability of HSV-2 in monogamous couples is nearly halved by the use of valacyclovir as suppressive therapy. GOAL:The goal of this study is to understand the potential impact of suppressive valacyclovir therapy on the transmission of HSV-2 within a po...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000258486.81492.a2
更新日期:2007-03-01 00:00:00
abstract:BACKGROUND:The Centers for Disease Control and Prevention recommends annual sexually transmitted infection (STI) and HIV testing and counseling for men who have sex with men (MSM) in the United States. We estimated the annual total direct medical cost of providing recommended STI and HIV testing and counseling services...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000341
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:Errors in the classification of male circumcision status could bias studies linking infection to lack of circumcision. GOAL:To determine the frequency and factors associated with the reproducibility of reporting circumcision status. STUDY DESIGN:Secondary analysis of data using logistic regression modeling...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200106000-00005
更新日期:2001-06-01 00:00:00
abstract:OBJECTIVES:In the Russian Federation, large sectors of the population regularly undergo mandatory occupational screening for sexually transmitted infections (STIs). Objectives of our study were to determine the prevalence of syphilis and gonorrhea in the screened occupational groups in Moscow and to conduct a cost-effe...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e31816f1c65
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND:The integration of HPV-16 DNA into the host genome is considered an important event in the progression of premalignant cervical lesions to cervical cancer. The aim of our study was to assess the prevalence of HPV-16 integration in anal cytologic specimens of HIV-1 infected men and its association with risk f...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e3181c9c23f
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND:The development of topical microbicides represents a new and exciting field in the prevention of sexually transmitted diseases, and it is especially important that candidate products undergo rigorous preclinical safety and efficacy testing before advancing to clinical trials. METHODS:We have developed a sta...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e31817dfdb8
更新日期:2008-10-01 00:00:00
abstract:BACKGROUND:Natural history data on human papillomavirus (HPV) incidence and its risk factors have not been reported on from young women in Norway. We report on incidence and predictors of HPV-6, 11, 16, and 18; 6 or 11; 16 or 18; or all 4. METHODS:A 48-month prospective study enrolled 898 women aged 16 to 24 between 1...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e31820a9324
更新日期:2011-07-01 00:00:00
abstract:BACKGROUND:In January 2001 we investigated an outbreak of Neisseria gonorrhoeae in a northern region of Alberta, Canada, and here we report on the epidemiology of the outbreak. GOAL:The goal was to examine the outbreak etiology and make recommendations for strengthening regional STD programs. STUDY DESIGN:Provincial ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200306000-00005
更新日期:2003-06-01 00:00:00
abstract:OBJECTIVE:To examine the effect of a laboratory-confirmed Chlamydia trachomatis (Ct) test result on subsequent sexual risk behavior in a large population-based screening program. METHODS:The study population consisted of 16- to 29-year-old participants of the Chlamydia Screening Implementation who completed Ct testing...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000234
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Ciprofloxacin (500 mg orally, single dose) is one of the recommended therapies for gonorrhea in Canada. In Canada, the first ciprofloxacin-resistant (CipR) Neisseria gonorrhoeae strain was isolated in 1993. Antimicrobial susceptibilities of N gonorrhoeae isolates were monitored as part of a national surveill...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,多中心研究
doi:10.1097/00007435-200212000-00008
更新日期:2002-12-01 00:00:00
abstract::Eighty-nine women prostitutes who underwent clinical and microbiologic examination were found to have gonococcal infection. The median age was 22; 92.1% were from urban areas. Nearly all the women prostitutes refrained from barrier methods (92.1%) and had contact with several partners (91.0%). The most frequent clinic...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::A solid-phase hemadsorption (SPHA) technique for the rapid detection of Treponema pallidum-specific IgM antibodies is described. The demonstration of these immunoglobulins permits differentiation between a recent and a long-lasting infection and facilitates the decision as to whether or not a patient should receive th...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:
更新日期:1980-04-01 00:00:00