Abstract:
BACKGROUND:In response to the increased hepatitis C virus (HCV) prevalence recently found among participants of the Amsterdam preexposure prophylaxis demonstration project, we evaluated HCV prevalence over time and the performance of the HCV-MOSAIC risk score for detection of HCV infection in HIV-negative men who have sex with men (MSM) attending the Amsterdam sexually transmitted infection (STI) clinic. METHODS:In October 2016, HIV-negative MSM were tested for anti-HCV and HCV RNA and completed the HCV-MOSAIC risk score. Anti-HCV prevalence was compared with that found in cross-sectional studies at the Amsterdam STI clinic (2007-2017). The time trend in HCV prevalence was modeled via logistic regression. The performance of the HCV-MOSAIC risk score, adjusted to identify prevalent HCV infection, was evaluated by calculating sensitivity and specificity. RESULTS:Of 504 HIV-negative MSM tested in October 2016, 5 were anti-HCV positive (1.0%, 95% confidence interval [CI], 0.4%-2.3%) and all were HCV RNA negative. Sensitivity and specificity of the adjusted HCV-MOSAIC risk score for prevalent infection were 80.0% (95% CI, 37.6%-96.4%) and 56.1% (95% CI, 51.7%-60.4%), respectively. The overall anti-HCV prevalence among 3264 HIV-negative MSM participating in cross-sectional studies at the Amsterdam STI clinic (2007-2017) was 0.8% (95% CI, 0.5%-1.2%) and did not change over time (P = 0.55). CONCLUSIONS:Anti-HCV prevalence among HIV-negative MSM attending the Amsterdam STI clinic in October 2016 was 1.0% and remained stable over time. We would therefore not recommend routine HCV screening of HIV-negative MSM at the STI clinic. However, given the increased prevalence among MSM using preexposure prophylaxis, periodic monitoring of HCV prevalence remains important.
journal_name
Sex Transm Disjournal_title
Sexually transmitted diseasesauthors
Newsum AM,van Rooijen MS,Kroone M,Bruisten SM,Matser A,Hogewoning A,Prins M,Heijman Tdoi
10.1097/OLQ.0000000000000877subject
Has Abstractpub_date
2018-12-01 00:00:00pages
813-817issue
12eissn
0148-5717issn
1537-4521pii
00007435-201812000-00008journal_volume
45pub_type
杂志文章abstract:BACKGROUND:A sensitive and specific method for detecting herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2) is important for diagnosing genital and cutaneous infections. GOAL:The goal of this study was to compare quantitative real-time polymerase chain reaction (qPCR) with virus culture for di...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200406000-00002
更新日期:2004-06-01 00:00:00
abstract:BACKGROUND:Since the mid-1990s, sexually transmitted infections (STIs) among men who have sex with men (MSM) have increased and appear to be related to more risky sexual behavior. We compare trends in hepatitis A, acute hepatitis B, and shigellosis with the trends of gonorrhea and infectious syphilis in Amsterdam MSM m...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e3181812cdf
更新日期:2008-11-01 00:00:00
abstract::Eighty-nine women prostitutes who underwent clinical and microbiologic examination were found to have gonococcal infection. The median age was 22; 92.1% were from urban areas. Nearly all the women prostitutes refrained from barrier methods (92.1%) and had contact with several partners (91.0%). The most frequent clinic...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the outcomes of a partner referral program at the sexually transmitted disease (STD) clinic in Amsterdam that encourages gonorrhea and chlamydia patients to refer their own partners to medical examination. STUDY DESIGN:355 patients with a confirmed infection cooperated in partner referral and gav...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199707000-00005
更新日期:1997-07-01 00:00:00
abstract::We believe this to be the first report of coexisting polymerase chain reaction (PCR)-confirmed primary genital and ocular syphilis in a patient with penicillin allergy treated with doxycycline. The case examines the use of nonpenicillin and corticosteroid treatment of ocular syphilis and highlights the risk of eye inv...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
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更新日期:2018-12-01 00:00:00
abstract:OBJECTIVES:To evaluate the incidence of early syphilis based on time from initiation of highly active antiretroviral therapy (HAART) in human immunodeficiency virus (HIV)-infected patients. STUDY DESIGN:Five hundred thirty-nine HIV-positive patients undergoing HAART were followed up to 4 years to identify early (prima...
journal_title:Sexually transmitted diseases
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doi:10.1097/OLQ.0b013e31815b0148
更新日期:2008-03-01 00:00:00
abstract:BACKGROUND:Little is known about cross-border sex-networking behaviors among men who have sex with men (MSM) GOAL: The goal of this study was to determine the prevalence of cross-border sex-networking in mainland China among MSM in Hong Kong and the associated risk behaviors STUDY:A telephone survey was conducted. A t...
journal_title:Sexually transmitted diseases
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更新日期:2004-09-01 00:00:00
abstract::Heretofore most people affected by warts of the oral cavity were children, but during the past decade adults have become the most frequently seen patients with warts in the mouth. The popularity of fellatio among heterosexuals, teenagers, and adults has contributed to the spread of oral warts. Of epidemiologic interes...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198410000-00001
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更新日期:2014-08-01 00:00:00
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journal_title:Sexually transmitted diseases
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更新日期:1990-10-01 00:00:00
abstract:OBJECTIVE:: To estimate the effects of reproductive tract infections (RTIs) on HIV acquisition among Zimbabwean and Ugandan women. METHODS:: A multicenter prospective observational cohort study enrolled 4439 HIV-uninfected women aged 18 to 35 attending family planning clinics in Zimbabwe and Uganda. Participants were ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,多中心研究
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更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:Although there is evidence for heightened sexually transmitted disease (STD) acquisition among women who experienced sexual violence, little is known about their patterns of STD testing, STD diagnosis, and STD treatment. METHODS:Data was drawn from cycle eight of the National Survey of Family Growth (2011-2...
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abstract:BACKGROUND:Adolescents are at high risk of sexually transmitted disease (STD)/HIV infection, and one vulnerable subgroup is African American females. The association between adolescents' previous experience of STD and recent sexual risk behaviors has been ill-defined. GOAL:The goal was to examine the associations betw...
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更新日期:2002-09-01 00:00:00
abstract:BACKGROUND:US Food and Drug Administration-approved enzyme-linked immunoassays (EIA) for determining type-specific herpes simplex virus (HSV) serostatus are widely used in clinical practice. We compared the performance of such assays with the University of Washington Western blot (UW WB) in patients who sought confirma...
journal_title:Sexually transmitted diseases
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doi:10.1097/OLQ.0000000000000689
更新日期:2017-12-01 00:00:00
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journal_title:Sexually transmitted diseases
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doi:10.1097/OLQ.0b013e3181fc6c65
更新日期:2011-04-01 00:00:00
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pub_type: 杂志文章,随机对照试验
doi:10.1097/OLQ.0b013e3181cfcb4c
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND:A prophylactic quadrivalent human papillomavirus (HPV) vaccine could benefit adult women if they are susceptible to incident genital HPV infections and are acquiring new infections with vaccine HPV types to which they were previously not exposed. This report presents baseline and prospective data from a rand...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e3181ad25ff
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVES:To investigate, among male injecting drug users (IDU), the relationships between higher risk IDU-related and sex-related behaviors. GOAL:To highlight the clustering effects of the 2 forms of risk behaviors. STUDY DESIGN:Behavioral surveillance surveys conducted in Sichuan were analyzed (n = 3105). RESULTS...
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doi:10.1097/01.olq.0000253339.49181.f9
更新日期:2007-08-01 00:00:00
abstract:BACKGROUND:Sexually transmitted disease clinics can deliver hepatitis vaccines to men who have sex with men, but have been reluctant to do so because of perceived low vaccination completion rates. GOAL:The goal was to evaluate hepatitis A and B vaccination eligibility, acceptance, and completion and the effectiveness ...
journal_title:Sexually transmitted diseases
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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更新日期:2003-09-01 00:00:00
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更新日期:2016-07-01 00:00:00
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更新日期:2015-03-01 00:00:00
abstract::In a large health insurance database in Germany, incidence of anogenital warts among 15- to 19-year-old females decreased from 316/100,000 person-years in 2007 to 242 in 2008 (23% reduction, P = 0.0001). The decrease started between the first and second quarter of 2007 (human papillomavirus vaccination was introduced ...
journal_title:Sexually transmitted diseases
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更新日期:2013-01-01 00:00:00
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更新日期:2013-03-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:1994-07-01 00:00:00
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pub_type: 杂志文章
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更新日期:2011-05-01 00:00:00
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更新日期:2016-04-01 00:00:00
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journal_title:Sexually transmitted diseases
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更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:Douching may interfere with determination of microbicide safety and effectiveness. This practice has not been adequately studied among women at risk of HIV infection. GOAL:This study assessed douching practices among women at risk of HIV infection in the United States. STUDY DESIGN:Data were collected on d...
journal_title:Sexually transmitted diseases
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更新日期:2002-07-01 00:00:00
abstract::Identifying pathogen-specific signs or symptoms of nongonococcal urethritis could improve syndromic management accuracy. We evaluated nongonococcal urethritis signs and symptoms in 220 men with single-pathogen infections (Chlamydia trachomatis, Mycoplasma genitalium, Trichomonas vaginalis, or Ureaplasma urealyticum) o...
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更新日期:2020-05-01 00:00:00