Abstract:
:In every society, congenital syphilis (CS) has significant medical, economic, societal and emotional burdens; these are poorly characterized but high. Inexplicably, the elimination of CS has failed to attract international attention. Yet, the cornerstones of programs to do this universally are in place, the recent development of new diagnostic tools offers the now-practical possibility of testing every pregnant woman, testing is cost-effective, and programs for the elimination of CS can be joined with other programs to enhance efficiency. The magnitude of the CS burden, globally, rivals that of HIV infection in neonates yet receives little attention. The newly proposed World Health Organization Strategy for the Global Elimination of Congenital Syphilis aims to mobilize resources and provide a plan to address this under-recognized health problem.
journal_name
Sex Transm Disjournal_title
Sexually transmitted diseasesauthors
Schmid GP,Stoner BP,Hawkes S,Broutet Ndoi
10.1097/01.olq.0000261456.09797.1bsubject
Has Abstractpub_date
2007-07-01 00:00:00pages
S5-10issue
7 Suppleissn
0148-5717issn
1537-4521pii
00007435-200707001-00003journal_volume
34pub_type
杂志文章,评审abstract::This report describes the cases of seven patients who had primary genital infection with herpes simplex virus and whose initial nontreponemal and treponemal tests for syphilis were nonreactive. On routine posttreatment examination, a change in the consistency of the ulcers was noticed, and the inguinal nodes, which ha...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198007000-00008
更新日期:1980-07-01 00:00:00
abstract:BACKGROUND:Oral human papillomavirus (HPV) and human herpesvirus-8 (HHV8) infections are sexually transmitted and respectively associated with the development of oropharyngeal carcinoma and Kaposi sarcoma. The aim of the study was to evaluate HPV prevalence and its possible correlation with HHV8 oral shedding, in relat...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e31826ef2da
更新日期:2012-11-01 00:00:00
abstract::Clinical observations indicate that herpes simplex virus type 1 (HSV-1) is significantly less likely than herpes simplex virus type 2 (HSV-2) to establish latency in (or reactivate from) sacral ganglionic tissue. In an effort to identify viral functions associated with latency, we analyzed HSV-1 isolates from three pa...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198607000-00005
更新日期:1986-07-01 00:00:00
abstract:BACKGROUND:Sexually transmitted disease (STD) transmission may occur if the time between dissolution and formation of sex partnerships, the gap, is shorter than mean duration of infectivity of STDs. GOAL:The goal was to examine gaps reported by a nationally representative sample of reproductive-age women. STUDY DESIG...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200303000-00009
更新日期:2003-03-01 00:00:00
abstract:BACKGROUND:We previously demonstrated a decrease in bacterial vaginosis (BV) and an increase in Lactobacillus colonization among randomized controlled trial (RCT) participants who received monthly oral periodic presumptive treatment (PPT; 2 g metronidazole + 150 mg fluconazole). Posttrial data were analyzed to test the...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,随机对照试验
doi:10.1097/OLQ.0b013e31824790d7
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:Chronic nongonococcal urethritis (NGU) is a well-recognized clinical problem in genitourinary medicine clinics, but its etiology and optimal management are poorly understood. GOAL:The authors showed previously that antibody to chlamydial hsp60 is associated with urethritis 30 to 92 days after treatment of a...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200302000-00007
更新日期:2003-02-01 00:00:00
abstract::Most Australian men who have sex with men who underwent rapid testing for syphilis using the Determine Syphilis TP immunoassay indicated a preference for rapid testing over conventional serology. Most also indicated that they would test for syphilis more frequently if rapid syphilis testing was available in a clinic s...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/olq.0b013e3181d707de
更新日期:2010-09-01 00:00:00
abstract::A man developed HIV-1 antibodies, which disappeared spontaneously. He had negative HIV viral load and p24 antigen tests and did not develop immunosuppression. Further investigations suggest the HIV-positive result was a nonspecific reaction. An alternative explanation is that he was exposed to HIV and had a "near-miss...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000258315.91807.70
更新日期:2007-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The past 10 years' wave of syphilis epidemics has challenged syphilis control programs. Although apparently connected to drugs-for-sex trading of crack cocaine, the genesis and resolution of these epidemics is poorly understood. GOALS OF THE STUDY:The goals of this study were to develop a mat...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199601000-00008
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:HerpeSelect HSV-1 and HSV-2 ELISAs are glycoprotein G-based, type-specific antibody detection tests that are approved by the US Food and Drug Administration for diagnosis of genital herpes. GOAL:The goal was to determine seroconversion times by means of HerpeSelect ELISAs. STUDY DESIGN:Four-hundred thirtee...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200304000-00007
更新日期:2003-04-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to provide updated estimates of the average lifetime medical cost per infection for chlamydia, gonorrhea, and trichomoniasis. METHODS:We adapted a published decision tree model that allowed for 7 possible outcomes of infection: (1) symptomatic infection, treated, no sequelae; (...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000001357
更新日期:2021-01-23 00:00:00
abstract:BACKGROUND:This study examined condom use and sexually transmitted infection (STI) testing among unmarried, non-cohabiting women and men who had multiple past-year partnerships or perceived their partner's involvement in another sexual relationship. METHODS:We identified 5868 and 5330 unmarried, non-cohabiting sexuall...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000001067
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:Sexually transmitted infections (STIs) continue to exert a tremendous health burden on women in developing countries. Poor socioeconomic status, inadequate knowledge, lack of diagnostic facilities, and shortages of effective treatment all contribute to the high incidence of STIs. The use of clinical algorith...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199909000-00010
更新日期:1999-09-01 00:00:00
abstract:OBJECTIVE:To evaluate the outcomes of a partner referral program at the sexually transmitted disease (STD) clinic in Amsterdam that encourages gonorrhea and chlamydia patients to refer their own partners to medical examination. STUDY DESIGN:355 patients with a confirmed infection cooperated in partner referral and gav...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199707000-00005
更新日期:1997-07-01 00:00:00
abstract::Metronidazole-resistant trichomoniasis is an uncommon condition that presents significant therapeutic challenges. Combination therapy with high-dose oral tinidazole and vaginal paromomycin cream has been uniformly successful. We present a case report of a patient who responded to combination therapy with high-dose ora...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000903
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVES:To evaluate the incidence of early syphilis based on time from initiation of highly active antiretroviral therapy (HAART) in human immunodeficiency virus (HIV)-infected patients. STUDY DESIGN:Five hundred thirty-nine HIV-positive patients undergoing HAART were followed up to 4 years to identify early (prima...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e31815b0148
更新日期:2008-03-01 00:00:00
abstract:OBJECTIVES:To examine the epidemiology of multiple infections in teenagers and their contacts. GOAL:To demonstrate a network approach to the prevalence of STDs/HIV. STUDY DESIGN:A community-based network study of ethnographically representative adolescents. RESULTS:Of the 512 interviewees, 90% of the boys and 80% of...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000258132.06764.a1
更新日期:2007-08-01 00:00:00
abstract:BACKGROUND:Incorrect condom use is a common problem that can undermine their prevention impact. We assessed the prevalence of 2 condom use problems, breakage/slippage and partial use, compared problems by partnership type, and examined associations with respondent, partner, and partnership characteristics. METHODS:Dat...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,多中心研究
doi:10.1097/OLQ.0b013e31825ef325
更新日期:2012-09-01 00:00:00
abstract::Both neurosyphilis and diplopia are widely known medical terms. Nevertheless, low clinical awareness by the physician and the often-overlooked presentation of diplopia, make the combination of neurosyphilis and diplopia rarely observed. In this article, we report 2 neurosyphilitic patients presenting with diplopia and...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,评审
doi:10.1097/OLQ.0000000000000703
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:A prophylactic quadrivalent human papillomavirus (HPV) vaccine could benefit adult women if they are susceptible to incident genital HPV infections and are acquiring new infections with vaccine HPV types to which they were previously not exposed. This report presents baseline and prospective data from a rand...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e3181ad25ff
更新日期:2009-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The care of patients with first episode and recurrent genital herpes differs with respect to therapy and source partner evaluation. Of 498 persons who presented with what appeared by history and symptoms to be a first episode of genital herpes, we identified 41 who had serologic evidence of re...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199904000-00007
更新日期:1999-04-01 00:00:00
abstract:BACKGROUND:Obstetric and gynecologic complications associated with bacterial vaginosis and trichomoniasis have heightened awareness of these conditions, and thus metronidazole's role in obstetric and gynecologic practice continues to increase. GOAL OF THIS STUDY:To review the clinical indications for metronidazole in ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,评审
doi:
更新日期:1995-11-01 00:00:00
abstract:BACKGROUND:The epidemiology of sexually transmitted infections (STIs) and HIV in Vanuatu is poorly defined. GOAL:The goal was to determine the prevalence of laboratory-confirmed gonorrhea, chlamydia, trichomoniasis, syphilis seroreactivity, and HIV among pregnant women in Vila, Vanuatu. STUDY DESIGN:A cross-sectional...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200304000-00017
更新日期:2003-04-01 00:00:00
abstract:BACKGROUND AND GOAL:Patients with sexually transmitted diseases (STDs) serve as a bridge population to transmit HIV from higher-risk to lower-risk populations. Our goal was to understand the level of risk behaviors and HIV/STD-related knowledge as well as attitudes among STD patients in China. STUDY DESIGN:An anonymou...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.OLQ.0000081394.94426.7A
更新日期:2003-08-01 00:00:00
abstract:BACKGROUND:Natural history data on human papillomavirus (HPV) incidence and its risk factors have not been reported on from young women in Norway. We report on incidence and predictors of HPV-6, 11, 16, and 18; 6 or 11; 16 or 18; or all 4. METHODS:A 48-month prospective study enrolled 898 women aged 16 to 24 between 1...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e31820a9324
更新日期:2011-07-01 00:00:00
abstract::The human cervicovaginal mucosa is the primary target of HIV-1 infection during male to female transmission. This tissue contains the the full spectrum of cell types and immune modulators that comprise both the innate and adaptive arms of the immune system. Mounting evidence indicates that mucosal epithelial cells are...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,评审
doi:10.1097/OLQ.0b013e3181994191
更新日期:2009-03-01 00:00:00
abstract:BACKGROUND:Prioritizing interventions for patients with syphilis who are part of large or interconnected sexual networks may be high yield for partner services, and identifying venues named by patients with syphilis who report high numbers of partners may help identify such networks. In this analysis, we explore differ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000116
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVES:A sharp increase in the incidence of gonorrhea has been observed in Tel Aviv, Israel, since 1999. Almost one half of interviewed patients admitted contracting the infection from a sex worker. In two thirds of the cases, oral sex (fellatio) was the most probable route of acquiring the disease. In the current ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000204675.92459.3c
更新日期:2006-08-01 00:00:00
abstract:BACKGROUND:The cerebrospinal fluid (CSF)-Venereal Disease Research Laboratory (VDRL) test is only 27% sensitive for diagnosing neurosyphilis. Discriminant analysis, used on 124 patients, shows that other commonly used laboratory tests can, in combination, identify 87% of patients with neurosyphilis with 94% specificity...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199609000-00008
更新日期:1996-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The Cuban Ministry of Public Health plans to implement the syndromic approach to sexually transmitted diseases in persons with urethral or vaginal syndrome in Cuba using 500 mg ciprofloxacin as therapy. Although the emergence of clinical isolates of Neisseria gonorrhoeae with decreased suscept...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200102000-00004
更新日期:2001-02-01 00:00:00