Abstract:
PURPOSE OF REVIEW:Atrial fibrillation after cardiac surgery is associated with adverse outcomes and increased costs. Accordingly, therapy should be provided to prevent postoperative atrial fibrillation. The evaluation of therapies to do so is an area of active investigation with significant recent advances. The purpose of this review is to summarize these recent advances in the context of our previous knowledge base regarding the prevention of postoperative atrial fibrillation. RECENT FINDINGS:Recent evaluations of therapy to prevent postoperative atrial fibrillation have raised the prominence of prophylactic amiodarone, redefined the efficacy of prophylactic standard beta-blockers in contemporary cardiac surgical populations, provided further evidence for the use of prophylactic sotalol, magnesium, and atrial pacing, and identified new approaches, including the use of combination therapy, for the prevention of postoperative atrial fibrillation. SUMMARY:According to newly released ACC/AHA/ESC guidelines, use of standard beta-blockers or amiodarone to prevent postoperative atrial fibrillation have a level of evidence of A. Use of prophylactic sotalol has a level of evidence of B, while the use of prophylactic intravenous magnesium or atrial pacing has a lower level of evidence. The use of novel and combination therapies continues to be an area of active investigation.
journal_name
Curr Opin Cardioljournal_title
Current opinion in cardiologyauthors
Mitchell LBdoi
10.1097/HCO.0b013e3280117cc5subject
Has Abstractpub_date
2007-01-01 00:00:00pages
18-24issue
1eissn
0268-4705issn
1531-7080pii
00001573-200701000-00005journal_volume
22pub_type
杂志文章,评审abstract::Coronary artery bypass surgery performed in patients with coronary artery disease and left ventricular dysfunction improves survival compared with antianginal therapy alone. The mechanisms for this survival advantage with revascularization therapy have not been systematically elucidated. Many of these patients have "h...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199607000-00008
更新日期:1996-07-01 00:00:00
abstract::Large databases are being used for outcome prediction analysis with increasing frequency. This review examines four separate databases used to provide risk analysis in the cardiac surgery population. Populations in the databases range in size from 3500 to over 116,000 patients. All of the databases were applied on ...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199204000-00014
更新日期:1992-04-01 00:00:00
abstract:PURPOSE OF REVIEW:Hypertension (HTN) is a widespread and growing disease, with medication intolerance and side-effect present among many. To address these obstacles novel pharmacotherapy is an active area of drug development. This review seeks to explore future drug therapy for HTN in the preclinical and clinical arena...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000529
更新日期:2018-07-01 00:00:00
abstract::Currently 14 million individuals in the United States have coronary disease. Within the next 2 decades, this number is expected to increase to 21 million persons. To minimize the excessive risk of recurrent cardiac events in these people, evidence-based, cost-effective prevention strategies must be developed. This rev...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199907000-00005
更新日期:1999-07-01 00:00:00
abstract:PURPOSE OF REVIEW:The review is designed to outline the major developments in genetic testing in the cardiovascular arena in the past year or so. This is an exciting time in genetic testing as whole exome and whole genome approaches finally reach the clinic. These new approaches offer insight into disease causation in ...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000055
更新日期:2014-05-01 00:00:00
abstract:PURPOSE OF REVIEW:While the prognostic power of adenosine single photon emission computed tomography myocardial perfusion imaging has been validated in multiple patient populations including those with known or suspected coronary artery disease, the utility of this modality in assessing risk after an acute myocardial i...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0b013e32820652c9
更新日期:2007-09-01 00:00:00
abstract::Though tachyarrhythmias occur commonly in patients with the Wolff-Parkinson-White syndrome, many patients remain asymptomatic. Recent studies suggest that routine electrophysiologic testing in these individuals is of limited value. However, electrophysiologic testing remains very helpful in the symptomatic patient fo...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:
更新日期:1991-02-01 00:00:00
abstract:PURPOSE OF REVIEW:Viability assessment has a key role in the management of patients with ischemic heart disease. Positron emission tomography (PET) is a unique modality that evaluates myocardial viability via assessing the tissues metabolic and perfusion properties. The mainstay of metabolic imaging relies on glucose m...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000652
更新日期:2019-09-01 00:00:00
abstract::The ECG is the most widely used noninvasive diagnostic and prognostic test administered to patients with suspected or proven coronary artery disease. When considering appropriate use of the electrocardiogram, physicians need to examine the clinical question being asked, the additional information that can be derived,...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199208000-00008
更新日期:1992-08-01 00:00:00
abstract:PURPOSE OF REVIEW:On the very solid background of experimental and clinical studies pointing to the cardiovascular risks associated with depressed vagal reflexes and supported by specific experiments in animal models of heart failure, we are witnessing a rapidly growing interest in the very untraditional approach to th...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0b013e3283413961
更新日期:2011-01-01 00:00:00
abstract::Angiogenesis, the de novo formation of new vasculature, is a critical response to ischemia that provides neovascularization of ischemic tissues. In therapeutic angiogenesis, an angiogen--a mediator that induces angiogenesis--is delivered to targeted tissues, augmenting the native angiogenic process and enhancing reper...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199911000-00012
更新日期:1999-11-01 00:00:00
abstract::Myocardial contrast echocardiography (MCE) is an emerging technique in which microbubble contrast agents are visualized in the coronary microvasculature. MCE is an ideal modality for the noninvasive evaluation of acute coronary syndromes because it provides portable, simultaneous assessment of regional wall motion and...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-200209000-00003
更新日期:2002-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Valvular heart disease is often associated with significant morbidity and mortality. Surgical treatment of stenotic or regurgitant valvular lesions can alter the natural history of the disease process, yielding excellent short and long-term results, meaning that this has been accepted as the gold stan...
journal_title:Current opinion in cardiology
pub_type: 杂志文章
doi:10.1097/HCO.0b013e3282a14dc8
更新日期:2007-09-01 00:00:00
abstract:PURPOSE OF REVIEW:The aim of this article is to review the current status of optimal revascularization strategies in patients presenting with multivessel coronary artery disease. RECENT FINDINGS:Coronary artery bypass surgery is the gold standard for patients with multivessel disease. Recent developments in the interv...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/01.hco.0000245738.40088.70
更新日期:2006-11-01 00:00:00
abstract::Recent data have emerged to help guide the use of implantable pacemakers and implantable defibrillators in patients who have hypertrophic cardiomyopathy (HCM). Controlled studies of the use of dual chamber pacemakers to treat outflow tract obstruction in HCM have shown little benefit, and have raised the possibility t...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-200101000-00009
更新日期:2001-01-01 00:00:00
abstract:PURPOSE OF REVIEW:To describe the electrophysiological profile and the clinical portfolio of dronedarone, a new multichannel-blocking antiarrhythmic drug developed for the treatment of atrial fibrillation. RECENT FINDINGS:Dronedarone is a derivative of amiodarone that is free of iodine and less lipophilic. The drug ha...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0b013e32833354e4
更新日期:2010-01-01 00:00:00
abstract::Although it has been the topic of intense medical and surgical attention for over 20 years, the coexistence of severe carotid artery disease in patients undergoing coronary artery bypass graft continues to be a major cause of perioperative morbidity and mortality. Refinements in diagnostic modalities, mainly by duplex...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199609000-00012
更新日期:1996-09-01 00:00:00
abstract::Management of aortic valve disease follows traditional algorithms: initial gross diagnosis, noninvasive imaging and quantitation, possible catheterization or angiography, and medical treatment until symptoms of prognosis prediction indicates surgery. Most advances in this subject reflect improved technology and additi...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199403000-00003
更新日期:1994-03-01 00:00:00
abstract::Over the past year, significant new advances have been made in preventive cardiology. New trials of lipid lowering, estrogen therapy, and hypertension control have added to our understanding of the pathophysiology and prevention of coronary atherosclerosis. This review highlights these new trials and provides insight ...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199909000-00006
更新日期:1999-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Despite numerous advances in coronary interventional techniques, the frequent occurrence of restenosis continues to plague interventional cardiology. With the widespread use of drug-eluting stents, there is a need to reexamine critically the roles of the various interventional techniques currently ava...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/01.hco.0000133658.77024.59
更新日期:2004-09-01 00:00:00
abstract::In the past 2 years, significant advances have been made in class III antiarrhythmic drug therapy. In patients with ventricular arrhythmias and implantable cardioverter defibrillators (ICDs), antiarrhythmic agents are increasingly being used as adjunct therapy to decrease the frequency of ICD discharges. Sotalol was r...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-200001000-00006
更新日期:2000-01-01 00:00:00
abstract::Hypertrophic cardiomyopathy has been shown to be a genetically heterogeneous disorder, linked to at least four different loci on chromosomes 14, 1, 15, and 11. Thus far, three genes have been identified that harbor mutations leading to hypertrophic cardiomyopathy. These genes--cardiac beta myosin heavy chain, alpha tr...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199505000-00010
更新日期:1995-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Our understanding of the interactions of genes and pathways during heart development continues to expand with our knowledge of the genetic basis of congenital heart disease. Along with the discovery of specific genes that cause lesions, recent research has focused on the interactions of some previousl...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0b013e328337b4ce
更新日期:2010-05-01 00:00:00
abstract:PURPOSE OF REVIEW:To provide a broad overview of the current state of knowledge of coronary artery bypass grafting with bilateral internal thoracic artery (BITA). RECENT FINDINGS:There exists a large body of literature from mostly observational studies supporting the use of BITA in patients undergoing coronary artery ...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000431
更新日期:2017-09-01 00:00:00
abstract::Assessment of the pulmonary circulation and right ventricular function is a cornerstone in the evaluation of the patient as a potential heart transplant recipient. The importance of pulmonary hypertension is linked to outcomes in the posttransplant period. Preoperative pulmonary vascular resistance is an independent r...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-200303000-00012
更新日期:2003-03-01 00:00:00
abstract:PURPOSE OF REVIEW:We provide a concise review of recent studies focusing on the management of patients with acute heart failure (AHF). RECENT FINDINGS:In well designed randomized trials, no mortality benefit has been observed with the use of diuretics, ultrafiltration, inotropes and vasodilators in AHF. Recent trials ...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000485
更新日期:2018-03-01 00:00:00
abstract::With 550,000 new cases each year, congestive heart failure is a major medical problem. Several medical therapies, including digoxin, angiotensin-converting enzyme inhibitors, and beta-blockers, have reduced the number of re-hospitalizations and slowed the progression of congestive heart failure. Angiotensin-converting...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-200201000-00014
更新日期:2002-01-01 00:00:00
abstract:PURPOSE OF REVIEW:A recently published study has alerted the cardiovascular community to the existence of a significant and previously unrecognized risk of subclinical valve thrombosis following implantation of surgical and catheter-based bioprosthetic valves. The purpose of this article is to review our current unders...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000373
更新日期:2017-03-01 00:00:00
abstract:PURPOSE OF REVIEW:To illustrate the limitations of predictive risk models in cardiac surgery, highlight the difficulty in interpreting risk-adjusted outcome analysis and discuss the challenges of making clinical decisions based on risk predictions, particularly in high-risk patients. RECENT FINDINGS:Predictive risk mo...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0b013e32831217ed
更新日期:2008-11-01 00:00:00
abstract::Three-dimensional echocardiography depicts the heart and its structures in their realistic forms. This capability decreases variability both in the quality and the interpretation of complex pathology, among investigators. Therefore, it is likely that the method will become the standard echocardiography examination in ...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199811000-00002
更新日期:1998-11-01 00:00:00