The molecular genetics of hypertrophic cardiomyopathy.

abstract：PURPOSE OF REVIEW:There is controversy regarding the optimal choice of prosthetic valves in patients less than 65 years of age requiring mitral valve replacement (MVR). Recently, trends for valve replacement are moving towards biological prosthesis also in younger patients, which is justified by the fact that a later v...

journal_title：Current opinion in cardiology

authors： Reineke DC,Heinisch PP,Winkler B,Englberger L,Carrel TP

更新日期：2015-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Infective endocarditis continues to pose major challenges in diagnosis and management despite advances in understanding the epidemiology, microbiology, and pathology of the disease. The purpose of this article is to provide a review of diagnosis, microbiology, and treatment of infective endocarditis, ...

journal_title：Current opinion in cardiology

authors： Devlin RK,Andrews MM,von Reyn CF

更新日期：2004-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to update the cardiovascular clinician on the current status of surgical therapies aimed at achieving reverse ventricular remodeling. RECENT FINDINGS:Relevant research focusing on mechanical options for reverse ventricular remodeling will be referenced and summarized. SUMMA...

journal_title：Current opinion in cardiology

authors： McGee EC,Gillinov AM,McCarthy PM

更新日期：2006-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an overview of recent clinical trial findings relevant to cardiovascular risk management in patients with diabetes. RECENT FINDINGS:Recent trial evidence has demonstrated benefits of routine blood pressure (BP) lowering, regardless of initial BP levels, in people with type 2 diabetes. In a...

journal_title：Current opinion in cardiology

authors： Patel A,Joshi R,de Galan B

更新日期：2009-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Cardiovascular implantable electronic devices are widely used to treat symptomatic arrhythmias, prevent sudden cardiac death, and improve symptoms and cardiac function. Continued population growth and expanding indications have resulted in a progressive increase in the number of cardiovascular implant...

journal_title：Current opinion in cardiology

authors： Sadek MM,Goldstein W,Epstein AE,Schaller RD

更新日期：2016-01-01 00:00:00

abstract：:Although activation of the endocrine renin-angiotensin system with consequent vasoconstriction and salt retention have long been known as the hallmarks of the early phase of renovascular hypertension, the recent recognition of a local vascular angiotensin system and the understanding of the process of vascular remodel...

journal_title：Current opinion in cardiology

authors： Ma AO,Gibbons GH

更新日期：1994-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Ablation for atrial fibrillation has become a widely accepted and practiced treatment for this arrhythmia. While this treatment has traditionally been reserved for second-line therapy in patients who have failed drug therapy, ablation is now being contemplated for first-line treatment. This review out...

journal_title：Current opinion in cardiology

authors： Verma A

更新日期：2008-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Ticagrelor is a new, direct acting, reversibly binding P2Y12 receptor antagonist with more potent inhibition of platelets than clopidogrel and which does not require metabolic activation. It was compared with clopidogrel, on a background of the standard of care in a randomized trial in the Platelet In...

journal_title：Current opinion in cardiology

authors： Held C

更新日期：2012-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Truncating variants in the TTN gene (TTNtv) are frequently identified in patients with dilated cardiomyopathy (DCM) but are also present in apparently healthy people in the general population. Consequently, there is considerable uncertainty about what it means for any single individual if a TTNtv is f...

journal_title：Current opinion in cardiology

authors： Fatkin D,Huttner IG

更新日期：2017-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Changing demands in healthcare, new leadership structures and physician preferences on work-life balance have made culture, teamwork and engagement vitally important for the long-term success of medical practices. With recent emphasis placed on culture, teamwork and engagement, leaders have had to acq...

journal_title：Current opinion in cardiology

authors： Samai C,Campbell R

更新日期：2021-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the electrophysiological profile and the clinical portfolio of dronedarone, a new multichannel-blocking antiarrhythmic drug developed for the treatment of atrial fibrillation. RECENT FINDINGS:Dronedarone is a derivative of amiodarone that is free of iodine and less lipophilic. The drug ha...

journal_title：Current opinion in cardiology

authors： Duray GZ,Ehrlich JR,Hohnloser SH

更新日期：2010-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Cardiovascular disease (CVD) is the leading cause of morbidity and premature mortality in Europe and the United States, and is increasingly common in developing countries. High-density lipoprotein cholesterol (HDL-C) is an independent risk factor for CVD and is superior to low-density lipoprotein chol...

journal_title：Current opinion in cardiology

authors： Schofield JD,France M,Ammori B,Liu Y,Soran H

更新日期：2013-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Due to complex venous anatomy and limitations in lead delivery tools and technology, the incidence of failed left-ventricular lead implants continues to be as high as 10%. RECENT FINDINGS:A move towards an interventional approach to left-ventricular lead implantation has provided viable alternatives ...

journal_title：Current opinion in cardiology

authors： Manlucu J,Yee R

更新日期：2014-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The intra-aortic balloon pump (IABP) has been used as a cardiac assist device in various clinical situations since 1968 on the basis of the physiological principles and observational data, with little randomized data until recently. RECENT FINDINGS:Recently published randomized controlled trials (RCT...

journal_title：Current opinion in cardiology

authors： Ihdayhid AR,Chopra S,Rankin J

更新日期：2014-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an overview on the most recent evidence for the use of extracorporeal and peritoneal ultrafiltration in heart failure, focusing on the major publications from the last few years. RECENT FINDINGS:There have been several studies investigating the possible use of extracorporeal and peritoneal...

journal_title：Current opinion in cardiology

authors： Marenzi G,Kazory A,Agostoni P

更新日期：2015-03-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the current evidence regarding the relationship between omega-3 fatty acid intake and atherosclerotic cardiovascular disease (ASCVD) risk. RECENT FINDINGS:Combined results from randomized controlled trials using low-dosage (≤1.8 g/day of ethyl esters) eicosapentaenoic acid (EPA) or EPA + d...

journal_title：Current opinion in cardiology

authors： Maki KC,Dicklin MR

更新日期：2020-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Troponins are a cornerstone for the diagnosis of myocardial infarction, assessment of risk and prognosis, and determination of antithrombotic and a revascularization strategy in patients with acute coronary syndromes. Newer assays with higher precision for detection of troponin levels are about to ent...

journal_title：Current opinion in cardiology

authors： White HD

更新日期：2008-07-01 00:00:00

abstract：:Increased carotid intima media thickness (IMT) is relatively simple, inexpensive, and reproducible noninvasive marker of global atherosclerotic disease. It is a frequently used experimental tool in epidemiologic studies to identify and follow cardiovascular disease. There is evidence that early detection of atheroscle...

journal_title：Current opinion in cardiology

authors： Sinha AK,Eigenbrodt M,Mehta JL

更新日期：2002-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Studies comparing outcomes in left-sided endocarditis based on the prosthesis selected for implantation are limited and no randomized studies have been performed. The purpose of this review is to summarize the best available studies to determine what prosthesis is most appropriate when valve replaceme...

journal_title：Current opinion in cardiology

authors： Moon MR

更新日期：2014-03-01 00:00:00

abstract：:The authors analyzed the early outcomes in two groups of patients undergoing coronary artery bypass grafting (CABG) with single versus bilateral internal thoracic arteries (ITA) in their institution. One thousand sixty-nine patients underwent CABG with single or bilateral ITAs from 1990 to 2000. Of these patients, 911...

journal_title：Current opinion in cardiology

authors： Walkes JC,Earle N,Reardon MJ,Glaeser DH,Wall MJ Jr,Huh J,Jones JW,Soltero ER

更新日期：2002-11-01 00:00:00

abstract：:Angiogenesis, the de novo formation of new vasculature, is a critical response to ischemia that provides neovascularization of ischemic tissues. In therapeutic angiogenesis, an angiogen--a mediator that induces angiogenesis--is delivered to targeted tissues, augmenting the native angiogenic process and enhancing reper...

journal_title：Current opinion in cardiology

authors： Hamawy AH,Lee LY,Crystal RG,Rosengart TK

更新日期：1999-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite its continued increase in prevalence in minorities, data regarding hypertension (HTN) control among such ethnic groups remains limited. This review highlights the most recent literature on the epidemiology, prevalence, and treatment strategies of HTN among four racial groups (non-Hispanic Whit...

journal_title：Current opinion in cardiology

authors： Bennett A,Parto P,Krim SR

更新日期：2016-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Cardiac resynchronization therapy (CRT) reduces morbidity and mortality in patients with mild-to-severe heart failure. However, up to 40% of CRT recipients are nonresponders. This review addresses important aspects with regard to the identification and management of CRT nonresponders. RECENT FINDINGS...

journal_title：Current opinion in cardiology

authors： Zhang Q,Zhou Y,Yu CM

更新日期：2015-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The efficacy of anticoagulation for valvular prostheses is the result of a delicate balance between the risk of thromboembolic (TE) events and bleeding. Here, we review data on anticoagulation for valve prostheses with a focus on clinical trials that address key unanswered questions. RECENT FINDINGS:...

journal_title：Current opinion in cardiology

authors： Yanagawa B,Whitlock RP,Verma S,Gersh BJ

更新日期：2016-03-01 00:00:00

abstract：PURPOSE OF REVIEW:High-density lipoprotein cholesterol (HDL-C) has been well established as an inverse predictor of coronary heart disease (CHD), and in recent years, investigations have focused on the genetic regulation of high-density lipoprotein. Although numerous candidate genes contribute to the low HDL-C phenotyp...

journal_title：Current opinion in cardiology

authors： Miller M,Zhan M

更新日期：2004-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Pulmonary hypertension is a progressive disease of the pulmonary vasculature characterized by increased vascular resistance and pressure overload of the right ventricle. This review aims to describe the diagnostic and prognostic role of echocardiography in pulmonary hypertension with particular consid...

journal_title：Current opinion in cardiology

authors： Bossone E,Ferrara F,Grünig E

更新日期：2015-11-01 00:00:00

abstract：:Clinical work in cardiac transplantation has focused on combating the major complications of this procedure, namely graft rejection and infection. Retrospective analyses suggest that prospective HLA typing, as is done in renal transplantation, may improve patient survival. Trials using FK 506 in cardiac transplantati...

journal_title：Current opinion in cardiology

authors： Nisco SJ,Reitz BA

更新日期：1993-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The appropriate treatment of patients with acute pulmonary embolism who present with right ventricular dysfunction but normal arterial blood pressure, and particularly the potential benefits of thrombolytic treatment in this setting, continue to be highly controversial. In the past year, several well ...

journal_title：Current opinion in cardiology

authors： Konstantinides S

更新日期：2005-11-01 00:00:00

abstract：:The mechanisms of pathogenesis of myocarditis have remained elusive. Despite the demonstration a decade ago that persistent viral infection of the myocardium occurred in many patients, a clear description of the pathologic progression has not been forthcoming. Over the past year, a number of studies have added to the ...

journal_title：Current opinion in cardiology

authors： Bowles NE,Towbin JA

更新日期：1998-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Open aortic arch surgery is highly invasive and may result in significant morbidity. Recent innovations in thoracic stent-graft technology have facilitated methods of replacing the aortic arch without deep hypothermic circulatory arrest or even cardiopulmonary bypass. We present a review of the curren...

journal_title：Current opinion in cardiology

authors： Desai ND,Szeto WY

更新日期：2009-11-01 00:00:00