Immunologic and surgical developments in cardiac transplantation.

abstract：PURPOSE OF REVIEW:Coarctation of the aorta is the discrete narrowing of the proximal descending aorta and is the sixth most common lesion in congenital heart disease. Repair of the coarctation can relieve the obstruction, but recurrent coarctation and future aneurysm formation can occur, and a heightened risk of vascul...

journal_title：Current opinion in cardiology

authors： Tanous D,Benson LN,Horlick EM

更新日期：2009-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The Brugada syndrome has been investigated in depth since its description in 1992 both on a clinical and on a basic research level. Since the discovery of the first genetic defect in 1998, several genes have been subsequently identified. However, to date all these genes together explain only 30% of th...

journal_title：Current opinion in cardiology

authors： Campuzano O,Brugada R,Iglesias A

更新日期：2010-05-01 00:00:00

abstract：PURPOSE OF REVIEW:In this study, we review the evidence for both long-standing and newer oral antiplatelet agents as secondary prevention in coronary artery disease, and give our opinion on where each agent's treatment role lies. RECENT FINDINGS:Platelets play a pathological role in acute coronary syndromes and are th...

journal_title：Current opinion in cardiology

authors： Behan MW,Chew DP,Aylward PE

更新日期：2010-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Low cholesterol syndromes were considered curiosities. The present article reviews some hypolipidaemic disorders and the drugs developed from the insights they provided. RECENT FINDINGS:Abetalipopoproteinaemia and hypobetalipoproteinaemia are associated with low cholesterol concentrations and caused ...

journal_title：Current opinion in cardiology

authors： Handhle A,Viljoen A,Ramachandran R,Wierzbicki AS

更新日期：2020-07-01 00:00:00

abstract：PURPOSE OF REVIEW:For over a decade, vulnerabilities in the healthcare industry have been identified. Medical devices such as cardiovascular implantable electronic devices (CIEDs) are particularly concerning because of direct threats to patient safety and protected health information (PHI). Although these vulnerabiliti...

journal_title：Current opinion in cardiology

authors： Tomaiko E,Zawaneh MS

更新日期：2021-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To evaluate whether long-term antiplatelet therapy may be effective and well tolerated. RECENT FINDINGS:Five important studies assessed the efficacy and safety of clopidogrel therapy in different settings. However, the problems concerning the duration of therapy are based substantially on the Clopido...

journal_title：Current opinion in cardiology

authors： Bolognese L,Angiolillo DJ

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Valvular heart disease is often associated with significant morbidity and mortality. Surgical treatment of stenotic or regurgitant valvular lesions can alter the natural history of the disease process, yielding excellent short and long-term results, meaning that this has been accepted as the gold stan...

journal_title：Current opinion in cardiology

authors： Sinha AK,Kini AS,Sharma SK

更新日期：2007-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This review discusses the role of statin therapy in patients with acute coronary syndromes. These drugs modulate endothelial function and stabilize atherosclerotic plaque by inhibiting oxidative stress and inflammation and may provide a relevant clinical benefit in unstable patients. RECENT FINDINGS:...

journal_title：Current opinion in cardiology

authors： Nusca A,Melfi R,Patti G,Di Sciascio G

更新日期：2010-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Treatment options for late-stage biventricular heart failure are limited but include medical therapy with intravenous inotropes, biventricular assist devices (Bi-VADs) and the total artificial heart (TAH). In this manuscript, we review the indications, surgical techniques and outcomes for the TAH. RE...

journal_title：Current opinion in cardiology

authors： Kasirajan V,Tang DG,Katlaps GJ,Shah KB

更新日期：2012-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To give an overview over the substantial advances in the diagnosis and management of Long-QT syndrome since its first description 60 years ago. RECENT FINDINGS:LQT syndrome remains the most common inherited arrhythmia and is a leading cause for sudden unexplained death accounting for up to 20-25% of ...

journal_title：Current opinion in cardiology

authors： Steinberg C

更新日期：2018-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe recent advancements in cardiovascular genetics made possible by leveraging next-generation sequencing (NGS), and to provide a framework for practical applications of genetic testing for hypertrophic (HCM), dilated (DCM), and arrhythmogenic right ventricular cardiomyopathies (ARVC). RECENT...

journal_title：Current opinion in cardiology

authors： Wilcox JE,Hershberger RE

更新日期：2018-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The severity of low-flow, low-gradient aortic stenosis cases continue to be misunderstood because of challenging diagnosis, and treatment remains complex. We discuss current diagnostic and treatment modalities for low-flow, low-gradient aortic stenosis. RECENT FINDINGS:This article summarizes current...

journal_title：Current opinion in cardiology

authors： Salemi A,Hameed I,Khan FM,Gaudino M

更新日期：2020-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Atrial fibrillation is an important cause of morbidity in the aging population. The mechanisms responsible for the triggering and maintenance of the chaotic atrial rhythm are still poorly understood. In this review, we will focus on the genetic aspects of atrial fibrillation, to understand causality, ...

journal_title：Current opinion in cardiology

authors： Pérez-Serra A,Campuzano O,Brugada R

更新日期：2017-05-01 00:00:00

abstract：:The incidence of congenital valvular heart disease has not significantly altered in recent decades. Major factors contributing to altered profiles of acquired valvular heart disease in the past few decades include an increased elderly segment of the population and increasing recognition of nonrheumatic forms of valvul...

journal_title：Current opinion in cardiology

authors： Rose AG

更新日期：1996-03-01 00:00:00

abstract：:A trend toward use of less invasive, nonsurgical approaches to the treatment of congenital heart disease has developed. Although transcatheter valve replacements and ventricular septal defect closures have already been performed in children, many other techniques and devices are being developed for the palliation of c...

journal_title：Current opinion in cardiology

authors： Levi DS,Alejos JC,Moore JW

更新日期：2003-03-01 00:00:00

abstract：:Magnetic resonance imaging of the cardiovascular system is now a well-recognized primary investigative technique for many conditions of structural abnormality in clinical cardiology, but the assessment of functional abnormality is also valuable and is increasingly being recognized by clinicians because of the accuracy...

journal_title：Current opinion in cardiology

authors： Taylor AM,Pennell DJ

更新日期：1996-11-01 00:00:00

abstract：PURPOSE OF REVIEW:A recently published study has alerted the cardiovascular community to the existence of a significant and previously unrecognized risk of subclinical valve thrombosis following implantation of surgical and catheter-based bioprosthetic valves. The purpose of this article is to review our current unders...

journal_title：Current opinion in cardiology

authors： Yanagawa B,Mazine A,Bhatt DL,Clavel MA,Côté N,Cheema AN,Pibarot P,Verma S

更新日期：2017-03-01 00:00:00

abstract：:Coronary artery bypass surgery performed in patients with coronary artery disease and left ventricular dysfunction improves survival compared with antianginal therapy alone. The mechanisms for this survival advantage with revascularization therapy have not been systematically elucidated. Many of these patients have "h...

journal_title：Current opinion in cardiology

authors： DeNofrio D,Loh E

更新日期：1996-07-01 00:00:00

abstract：:Though tachyarrhythmias occur commonly in patients with the Wolff-Parkinson-White syndrome, many patients remain asymptomatic. Recent studies suggest that routine electrophysiologic testing in these individuals is of limited value. However, electrophysiologic testing remains very helpful in the symptomatic patient fo...

journal_title：Current opinion in cardiology

authors： Wharton JM,Prystowsky EN

更新日期：1991-02-01 00:00:00

abstract：:Recent evidence indicates that infections or a pathogen burden contribute to the development and progression of atherosclerosis. While the mechanism of infection contributing to the pathogenesis is not fully elucidated, I hypothesize that heat shock proteins may be a link between infections and atherosclerosis. Heat s...

journal_title：Current opinion in cardiology

authors： Xu Q

更新日期：2003-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the current evidence regarding the relationship between omega-3 fatty acid intake and atherosclerotic cardiovascular disease (ASCVD) risk. RECENT FINDINGS:Combined results from randomized controlled trials using low-dosage (≤1.8 g/day of ethyl esters) eicosapentaenoic acid (EPA) or EPA + d...

journal_title：Current opinion in cardiology

authors： Maki KC,Dicklin MR

更新日期：2020-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to focus specifically on the indications, evolution of technique, and results of surgical ablation for atrial fibrillation. RECENT FINDINGS:With the introduction of the Cox-Maze IV procedure utilizing bipolar radiofrequency ablation and cryoablation, long-term studies have d...

journal_title：Current opinion in cardiology

authors： Lawrance CP,Henn MC,Damiano RJ Jr

更新日期：2015-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Statins are widely utilized for low-density lipoprotein lowering and for prevention of atherosclerotic cardiovascular disease. Although these drugs have a good safety record, increased risk of developing diabetes during extended use has recently garnered attention. Here we review clinical trial eviden...

journal_title：Current opinion in cardiology

authors： Sampson UK,Linton MF,Fazio S

更新日期：2011-07-01 00:00:00

abstract：:Our understanding of pediatric arrhythmias continues to evolve through natural history studies of paroxysmal supraventricular tachycardia, the congenital long QT syndrome, and postoperative atrial and ventricular tachyarrhythmias. The influence of the autonomic nervous system on cardiovascular function may play a rol...

journal_title：Current opinion in cardiology

authors： Kanter RJ

更新日期：1993-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Atrial fibrillation is the most common sustained cardiac arrhythmia and may cause significant morbidity. Current management strategies offer only modest success and may be associated with intolerable drug side effects or risk of procedural complications. As with other cardiac arrhythmias, the identifi...

journal_title：Current opinion in cardiology

authors： Gollob MH

更新日期：2006-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To compare the potential of high-density lipoprotein (HDL) cholesterol and apolipoprotein (apo) A-I, the major protein in HDL particles, in predicting cardiovascular risk. Pros and cons for using these risk markers are discussed. RECENT FINDINGS:Both HDL cholesterol and apoA-I are in most clinical co...

journal_title：Current opinion in cardiology

authors： Walldius G,Jungner I

更新日期：2007-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Vitamin D deficiency is common throughout the world, with a particularly high prevalence in northern latitudes and colder climates. Although the best known sequelae of vitamin D deficiency involve the musculoskeletal system, a growing body of evidence suggests that vitamin D status may influence cardi...

journal_title：Current opinion in cardiology

authors： Swales HH,Wang TJ

更新日期：2010-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The goal of this review is to offer an overview of the use of thrombolytic therapy in acute pulmonary embolism. Clinicians including internists, surgeons, pulmonologists, and other specialists continue to face decisions regarding massive and submassive acute pulmonary embolism in their daily routines....

journal_title：Current opinion in cardiology

authors： Tapson VF

更新日期：2012-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Heart failure prevalence is reaching epidemic proportion in the United States and is associated with significant morbidity and mortality. A large proportion of the mortality is the result of sudden cardiac death (SCD). Clinical trials have demonstrated the superiority of the implantable cardioverter/d...

journal_title：Current opinion in cardiology

authors： Rami T,Shih HT

更新日期：2004-05-01 00:00:00

abstract：:Large databases are being used for outcome prediction analysis with increasing frequency. This review examines four separate databases used to provide risk analysis in the cardiac surgery population. Populations in the databases range in size from 3500 to over 116,000 patients. All of the databases were applied on ...

journal_title：Current opinion in cardiology

authors： Park SE,Cmolik BL,Clark RE

更新日期：1992-04-01 00:00:00