Myocardial viability in patients with coronary artery disease and left ventricular dysfunction: transplantation or revascularization?

abstract：:Angiogenesis, the de novo formation of new vasculature, is a critical response to ischemia that provides neovascularization of ischemic tissues. In therapeutic angiogenesis, an angiogen--a mediator that induces angiogenesis--is delivered to targeted tissues, augmenting the native angiogenic process and enhancing reper...

journal_title：Current opinion in cardiology

authors： Hamawy AH,Lee LY,Crystal RG,Rosengart TK

更新日期：1999-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the electrophysiological profile and the clinical portfolio of dronedarone, a new multichannel-blocking antiarrhythmic drug developed for the treatment of atrial fibrillation. RECENT FINDINGS:Dronedarone is a derivative of amiodarone that is free of iodine and less lipophilic. The drug ha...

journal_title：Current opinion in cardiology

authors： Duray GZ,Ehrlich JR,Hohnloser SH

更新日期：2010-01-01 00:00:00

abstract：:The authors analyzed the early outcomes in two groups of patients undergoing coronary artery bypass grafting (CABG) with single versus bilateral internal thoracic arteries (ITA) in their institution. One thousand sixty-nine patients underwent CABG with single or bilateral ITAs from 1990 to 2000. Of these patients, 911...

journal_title：Current opinion in cardiology

authors： Walkes JC,Earle N,Reardon MJ,Glaeser DH,Wall MJ Jr,Huh J,Jones JW,Soltero ER

更新日期：2002-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Truncating variants in the TTN gene (TTNtv) are frequently identified in patients with dilated cardiomyopathy (DCM) but are also present in apparently healthy people in the general population. Consequently, there is considerable uncertainty about what it means for any single individual if a TTNtv is f...

journal_title：Current opinion in cardiology

authors： Fatkin D,Huttner IG

更新日期：2017-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Myocardial fibrosis is a common feature of many cardiomyopathies, including hypertrophic cardiomyopathy. Myocardial fibrosis has been shown to be reversible and treatable with timely intervention. Although early detection and assessment of fibrosis is crucial, adequate diagnostics are still in develop...

journal_title：Current opinion in cardiology

authors： Won S,Davies-Venn C,Liu S,Bluemke DA

更新日期：2013-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The Brugada syndrome has been investigated in depth since its description in 1992 both on a clinical and on a basic research level. Since the discovery of the first genetic defect in 1998, several genes have been subsequently identified. However, to date all these genes together explain only 30% of th...

journal_title：Current opinion in cardiology

authors： Campuzano O,Brugada R,Iglesias A

更新日期：2010-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an overview of recent clinical trial findings relevant to cardiovascular risk management in patients with diabetes. RECENT FINDINGS:Recent trial evidence has demonstrated benefits of routine blood pressure (BP) lowering, regardless of initial BP levels, in people with type 2 diabetes. In a...

journal_title：Current opinion in cardiology

authors： Patel A,Joshi R,de Galan B

更新日期：2009-07-01 00:00:00

abstract：:Cardiopulmonary bypass triggers a generalized inflammatory response that is largely mediated by activation of polymorphonuclear neutrophils, their adhesion to endothelial cells, and the subsequent release of cytotoxic products. It has been known for several years that the inflammatory response to extracorporeal circul...

journal_title：Current opinion in cardiology

authors： Menasché P

更新日期：1995-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Atrial fibrillation, the most common cardiac supraventricular arrhythmia, affects more than 5 million people worldwide. Increasing evidence has demonstrated that genetic factors play an important role in the pathogenesis of atrial fibrillation, and multiple genes responsible for atrial fibrillation ha...

journal_title：Current opinion in cardiology

authors： Hong K,Xiong Q

更新日期：2014-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Diabetes is an increasingly prevalent risk factor for coronary and other vascular disease. Recent trials in patients with diabetes have examined the effects of intensive glycemic control on cardiovascular outcomes, and treatment of common concomitant risk factors, in particular hypertension and dyslip...

journal_title：Current opinion in cardiology

authors： Webster MW

更新日期：2011-07-01 00:00:00

abstract：:Over the past year, significant new advances have been made in preventive cardiology. New trials of lipid lowering, estrogen therapy, and hypertension control have added to our understanding of the pathophysiology and prevention of coronary atherosclerosis. This review highlights these new trials and provides insight ...

journal_title：Current opinion in cardiology

authors： Foody JA

更新日期：1999-09-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an update on the management of patients with diabetes mellitus and requiring coronary revascularization. RECENT FINDINGS:Evidence continues to show that patients with diabetes mellitus and ischemic heart disease represent a very high-risk group of patients. Choice of stent appears importan...

journal_title：Current opinion in cardiology

authors： Mancini GBJ,Farkouh M,Verma S

更新日期：2017-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this article is to provide an overview of investigational work which has demonstrated the ability of MRI to define abnormalities caused by coronary heart disease. There have been numerous recent advances in the MRI assessment of coronary heart disease which warrant review. RECENT FINDI...

journal_title：Current opinion in cardiology

authors： Vick GW 3rd

更新日期：2009-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The presence of tricuspid regurgitation in the setting of right ventricular dysfunction is associated with poor prognosis. The purpose of this review is to describe the pathophysiology of functional tricuspid regurgitation, summarize the current reports favoring a more aggressive approach toward tricu...

journal_title：Current opinion in cardiology

authors： Pinney SP

更新日期：2012-05-01 00:00:00

abstract：:Fewer than 50 pediatric lung transplants are performed each year. Surgical advances in the field have resulted in improved operative outcomes and in technical innovations that have broadened both the target population and the donor pool. At the same time, late referral of critically ill patients and shortage of donor ...

journal_title：Current opinion in cardiology

authors： Bridges ND

更新日期：1998-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The ability of high-density lipoprotein cholesterol to reverse atherosclerosis and reduce cardiovascular disease has been shown in several randomized controlled trials. One mechanism by which high-density lipoprotein cholesterol protects the vascular system includes hemorheology, the study of blood fl...

journal_title：Current opinion in cardiology

authors： Moriarty PM,Gibson CA

更新日期：2005-07-01 00:00:00

abstract：PURPOSE OF REVIEW:This review aims to summarize recent reports on percutaneous coronary intervention (PCI) strategies for patients with ST-elevation myocardial infarction (STEMI) and multivessel coronary artery disease (CAD). RECENT FINDINGS:Recent randomized clinical trials and meta-analyses have suggested that patie...

journal_title：Current opinion in cardiology

authors： Thomas MP,Bates ER

更新日期：2017-11-01 00:00:00

abstract：:The COCPIT study, performed in a complete national cohort of adult patients consecutively listed for cardiac transplantation in Germany in 1997, found a beneficial effect only in the group that was at high risk of dying from heart failure without transplantation. If these results can be reproduced in other countries, ...

journal_title：Current opinion in cardiology

authors： Deng MC,Smits JM,De Meester J,Hummel M,Schoendube F,Scheld HH

更新日期：2001-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Due to complex venous anatomy and limitations in lead delivery tools and technology, the incidence of failed left-ventricular lead implants continues to be as high as 10%. RECENT FINDINGS:A move towards an interventional approach to left-ventricular lead implantation has provided viable alternatives ...

journal_title：Current opinion in cardiology

authors： Manlucu J,Yee R

更新日期：2014-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Although many reviews have focused on diet as a determinant of coronary heart disease (CHD), little is known about the use of specific nutrients or food products. The aim of this review was to examine the role of several functional foods, or nutraceuticals, in the prevention or treatment of CHD. RECE...

journal_title：Current opinion in cardiology

authors： Garcia-Rios A,Delgado-Lista J,Alcala-Diaz JF,Lopez-Miranda J,Perez-Martinez P

更新日期：2013-07-01 00:00:00

abstract：:The focus of this review is the advantages of simultaneously assessing myocardial perfusion and left ventricular function. Nuclear cardiology imaging techniques as well as the development of technetium-labeled perfusion tracers now permit combined myocardial-perfusion and left-ventricular function studies at a single ...

journal_title：Current opinion in cardiology

authors： Borges-Neto S,Shaw LK

更新日期：1999-11-01 00:00:00

abstract：:Hypertrophic cardiomyopathy is a primary myocardial disorder with an autosomal pattern of inheritance, characterized by asymmetric left ventricular hypertrophy with myocyte and myofibrillar disarray. Approximately 30% to 50% of all cases are accounted for by mutations in the beta-cardiac myosin heavy chain gene on chr...

journal_title：Current opinion in cardiology

authors： Vassalli G,Seiler C,Hess OM

更新日期：1994-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Thrombus formation, usually on a ruptured atherosclerotic plaque, is pivotal in the pathogenesis of ST segment elevation myocardial infarction (STEMI). This thrombus formation provides the milieu for re-occlusion of the infarct-related artery, the main location of re-infarction post-STEMI. Although ra...

journal_title：Current opinion in cardiology

authors： French JK,Burgess S,Chew DP

更新日期：2015-07-01 00:00:00

abstract：:Endocarditis remains a major worldwide problem despite significant advances in diagnostic and therapeutic interventions. This review centers on the recent studies that have been published in the past year concerning the epidemiologic, diagnostic, and therapeutic aspects of infective and noninfective endocarditis in bo...

journal_title：Current opinion in cardiology

authors： Farmer JA,Torre G

更新日期：1997-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Many patients requiring cardiac arrhythmia device surgery are on chronic oral anticoagulation therapy. The periprocedural management of their anticoagulation presents a dilemma to physicians, particularly in the subset of patients with moderate-to-high risk of arterial thromboembolic events. Physician...

journal_title：Current opinion in cardiology

authors： Birnie D,Healey JS,Krahn A,Essebag V,Sivakumaran S,Tang A,Simpson C

更新日期：2009-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Pulmonary hypertension is a progressive disease of the pulmonary vasculature characterized by increased vascular resistance and pressure overload of the right ventricle. This review aims to describe the diagnostic and prognostic role of echocardiography in pulmonary hypertension with particular consid...

journal_title：Current opinion in cardiology

authors： Bossone E,Ferrara F,Grünig E

更新日期：2015-11-01 00:00:00

abstract：:Over the past year, many advances have been made in the management of cardiac arrhythmias in the pediatric patient. It has become evident that the new surgical procedures for congenital cardiac disease can result in arrhythmia-associated morbidity and mortality. New pharmacologic agents such as adenosine have been s...

journal_title：Current opinion in cardiology

authors： Kaminer SJ,Gelband H

更新日期：1991-02-01 00:00:00

abstract：:Currently 14 million individuals in the United States have coronary disease. Within the next 2 decades, this number is expected to increase to 21 million persons. To minimize the excessive risk of recurrent cardiac events in these people, evidence-based, cost-effective prevention strategies must be developed. This rev...

journal_title：Current opinion in cardiology

authors： Blazing MA,O'Connor CM

更新日期：1999-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Rheumatic heart disease (RHD) affects over 30 million people worldwide. Substantial variation exists in the surgical treatment of patients with RHD. Here, we aim to review the surgical techniques to treat RHD with a focus on rheumatic mitral valve (MV) repair. We introduce novel educational paradigms ...

journal_title：Current opinion in cardiology

authors： Vervoort D,Ouzounian M,Yanagawa B

更新日期：2020-12-24 00:00:00

abstract：PURPOSE OF REVIEW:Atrial fibrillation is the most common sustained cardiac arrhythmia and may cause significant morbidity. Current management strategies offer only modest success and may be associated with intolerable drug side effects or risk of procedural complications. As with other cardiac arrhythmias, the identifi...

journal_title：Current opinion in cardiology

authors： Gollob MH

更新日期：2006-05-01 00:00:00