Abstract:
PURPOSE OF REVIEW:Valvular heart disease is often associated with significant morbidity and mortality. Surgical treatment of stenotic or regurgitant valvular lesions can alter the natural history of the disease process, yielding excellent short and long-term results, meaning that this has been accepted as the gold standard for therapy of valvular disease. Surgical procedures can be associated with a significant rate of perioperative complications, however. These procedures are particularly associated with unacceptably high short and long-term morbidity and mortality in the elderly - a population group that has grown steadily over the years. Elderly patients often have significant comorbidities that preclude a safe and durable surgical correction of the valvular lesions in up to 31% of these high-risk cases. This review provides an overview of recent developments in percutaneous valve therapeutics. RECENT FINDINGS:Over the last decade, numerous technical developments in valvular interventions have focused on percutaneous valve replacement. There are percutaneous valve replacements on the horizon that promise to offer a novel approach to correct valvular lesions, especially in this high-risk surgical population. SUMMARY:Several devices are presently being evaluated in feasibility trials, and many new ones are being developed. Results with semilunar valves have generally been better than the atrioventricular valves. Long-term results of these treatment modalities are still unknown.
journal_name
Curr Opin Cardioljournal_title
Current opinion in cardiologyauthors
Sinha AK,Kini AS,Sharma SKdoi
10.1097/HCO.0b013e3282a14dc8subject
Has Abstractpub_date
2007-09-01 00:00:00pages
471-7issue
5eissn
0268-4705issn
1531-7080pii
00001573-200709000-00012journal_volume
22pub_type
杂志文章abstract::Ambulatory blood pressure monitoring is becoming increasingly popular in the diagnosis and treatment of patients with hypertensive disorders. Widespread clinical use, however, has been limited by a lack of normative data and prospective, controlled clinical studies of its impact on subsequent cardiovascular morbidity ...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199309000-00007
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abstract:PURPOSE OF REVIEW:The possible role of several neurohormonal factors in pathogenesis of hypertension has been studied extensively both in humans and in experimental animal models. However, controversial data from some previous studies are indecisive and call for reassessment and development of new targets. This mini-re...
journal_title:Current opinion in cardiology
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journal_title:Current opinion in cardiology
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journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
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journal_title:Current opinion in cardiology
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journal_title:Current opinion in cardiology
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journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
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更新日期:2007-11-01 00:00:00
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journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199705000-00014
更新日期:1997-05-01 00:00:00
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journal_title:Current opinion in cardiology
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更新日期:2009-07-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2006-05-01 00:00:00
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journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199208000-00008
更新日期:1992-08-01 00:00:00
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journal_title:Current opinion in cardiology
pub_type: 临床试验,杂志文章,评审
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journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
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更新日期:2017-09-01 00:00:00
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journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
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journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-200201000-00004
更新日期:2002-01-01 00:00:00
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journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
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journal_title:Current opinion in cardiology
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doi:10.1097/00001573-200403000-00012
更新日期:2004-03-01 00:00:00
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journal_title:Current opinion in cardiology
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pub_type: 杂志文章,评审
doi:10.1097/HCO.0b013e3283470359
更新日期:2011-07-01 00:00:00
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journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
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更新日期:2002-01-01 00:00:00
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更新日期:2006-07-01 00:00:00
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journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
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更新日期:2018-07-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2005-03-01 00:00:00
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