Percutaneous valve replacement: a paradigm shift.

Abstract:

PURPOSE OF REVIEW:Valvular heart disease is often associated with significant morbidity and mortality. Surgical treatment of stenotic or regurgitant valvular lesions can alter the natural history of the disease process, yielding excellent short and long-term results, meaning that this has been accepted as the gold standard for therapy of valvular disease. Surgical procedures can be associated with a significant rate of perioperative complications, however. These procedures are particularly associated with unacceptably high short and long-term morbidity and mortality in the elderly - a population group that has grown steadily over the years. Elderly patients often have significant comorbidities that preclude a safe and durable surgical correction of the valvular lesions in up to 31% of these high-risk cases. This review provides an overview of recent developments in percutaneous valve therapeutics. RECENT FINDINGS:Over the last decade, numerous technical developments in valvular interventions have focused on percutaneous valve replacement. There are percutaneous valve replacements on the horizon that promise to offer a novel approach to correct valvular lesions, especially in this high-risk surgical population. SUMMARY:Several devices are presently being evaluated in feasibility trials, and many new ones are being developed. Results with semilunar valves have generally been better than the atrioventricular valves. Long-term results of these treatment modalities are still unknown.

journal_name

Curr Opin Cardiol

authors

Sinha AK,Kini AS,Sharma SK

doi

10.1097/HCO.0b013e3282a14dc8

subject

Has Abstract

pub_date

2007-09-01 00:00:00

pages

471-7

issue

5

eissn

0268-4705

issn

1531-7080

pii

00001573-200709000-00012

journal_volume

22

pub_type

杂志文章
  • Emerging clinical roles for ambulatory blood pressure monitoring.

    abstract::Ambulatory blood pressure monitoring is becoming increasingly popular in the diagnosis and treatment of patients with hypertensive disorders. Widespread clinical use, however, has been limited by a lack of normative data and prospective, controlled clinical studies of its impact on subsequent cardiovascular morbidity ...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-199309000-00007

    authors: Canzanello VJ,Sheps SG

    更新日期:1993-09-01 00:00:00

  • Transient receptor potential vanilloid channels in hypertension, inflammation, and end organ damage: an imminent target of therapy for cardiovascular disease?

    abstract:PURPOSE OF REVIEW:The possible role of several neurohormonal factors in pathogenesis of hypertension has been studied extensively both in humans and in experimental animal models. However, controversial data from some previous studies are indecisive and call for reassessment and development of new targets. This mini-re...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0b013e32830460ad

    authors: Wang DH

    更新日期:2008-07-01 00:00:00

  • Trials of cardiovascular risk factor management in type 2 diabetes.

    abstract:PURPOSE OF REVIEW:To provide an overview of recent clinical trial findings relevant to cardiovascular risk management in patients with diabetes. RECENT FINDINGS:Recent trial evidence has demonstrated benefits of routine blood pressure (BP) lowering, regardless of initial BP levels, in people with type 2 diabetes. In a...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0b013e32832a7b01

    authors: Patel A,Joshi R,de Galan B

    更新日期:2009-07-01 00:00:00

  • Coronary artery surgical technique.

    abstract::The increased use of arterial conduits in coronary artery bypass grafting is reflected in numerous publications addressing indications, choice of conduits, and possible side-effects. Besides the internal thoracic artery, the right gastroepiploic artery is becoming established, and the inferior epigastric artery is be...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-199311000-00004

    authors: Turina M

    更新日期:1993-11-01 00:00:00

  • Genetic cardiomyopathies.

    abstract:PURPOSE OF REVIEW:To describe recent advancements in cardiovascular genetics made possible by leveraging next-generation sequencing (NGS), and to provide a framework for practical applications of genetic testing for hypertrophic (HCM), dilated (DCM), and arrhythmogenic right ventricular cardiomyopathies (ARVC). RECENT...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0000000000000512

    authors: Wilcox JE,Hershberger RE

    更新日期:2018-05-01 00:00:00

  • Minimally invasive CABG.

    abstract::For more than three decades, conventional coronary artery bypass grafting (full sternotomy, cardiopulmonary bypass, and cardioplegic arrest) has been the treatment of choice for patients with multi-vessel coronary artery disease. However, neurologic injury secondary to ascending aortic manipulation and systemic inflam...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-200109000-00009

    authors: Filsoufi F,Aklog L,Adams DH

    更新日期:2001-09-01 00:00:00

  • Multiple extensive coronary artery stenting: does it compromise future surgical revascularization?

    abstract:PURPOSE OF REVIEW:In the era of percutaneous coronary intervention, surgeons are confronted with performing coronary artery bypass graft surgery on patients with previous balloon dilatation or stenting. This review evaluates the impact of previous percutaneous coronary intervention on patient survival and choice of opt...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0b013e3282f0795d

    authors: Al-Attar N,Nataf P

    更新日期:2007-11-01 00:00:00

  • Molecular genetics of congenital heart disease.

    abstract::This review of advances made toward understanding the molecular basis of congenital heart disease covers studies on subjects ranging from atrioventricular septal defects to zebrafish models. Genetically abnormal mice with atrioventricular septal defects have abnormal endocardial cushion development with the delayed ap...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-199705000-00014

    authors: Gelb BD

    更新日期:1997-05-01 00:00:00

  • Advances in the field of proprotein convertase subtilisin kexin type 9 inhibitors.

    abstract:PURPOSE OF REVIEW:Proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitors are promising therapies that inhibit the degradation of low-density lipoprotein (LDL) receptors in the hepatocyte and thus increase LDL cholesterol (LDL-C) uptake from the blood. This review summarizes main findings in the field of PCSK9...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0000000000000332

    authors: Eisen A,Giugliano RP

    更新日期:2016-11-01 00:00:00

  • Lipoprotein a: where are we now?

    abstract:PURPOSE OF REVIEW:To provide an update of the literature describing the link between lipoprotein a and vascular disease. RECENT FINDINGS:There is evidence that elevated plasma lipoprotein a levels are associated with coronary heart disease, stroke and other manifestations of atherosclerosis. Several mechanisms may be ...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0b013e32832ac21a

    authors: Tziomalos K,Athyros VG,Wierzbicki AS,Mikhailidis DP

    更新日期:2009-07-01 00:00:00

  • Cardiac connexins as candidate genes for idiopathic atrial fibrillation.

    abstract:PURPOSE OF REVIEW:Atrial fibrillation is the most common sustained cardiac arrhythmia and may cause significant morbidity. Current management strategies offer only modest success and may be associated with intolerable drug side effects or risk of procedural complications. As with other cardiac arrhythmias, the identifi...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/01.hco.0000221574.95383.6f

    authors: Gollob MH

    更新日期:2006-05-01 00:00:00

  • The use of electrocardiography as a diagnostic and prognostic tool in coronary artery disease.

    abstract::The ECG is the most widely used noninvasive diagnostic and prognostic test administered to patients with suspected or proven coronary artery disease. When considering appropriate use of the electrocardiogram, physicians need to examine the clinical question being asked, the additional information that can be derived,...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-199208000-00008

    authors: Al-Joundi B,Chaitman BR

    更新日期:1992-08-01 00:00:00

  • The role of coronary revascularization in the management of heart failure: identification of candidates and review of results.

    abstract::As a result of the increasing size of waiting lists and lengthening of waiting times for heart transplantation, coronary revascularization has emerged as an important therapeutic option in the management of patients with ischemic cardiomyopathy. A critical challenge is the identification of candidates with regions of ...

    journal_title:Current opinion in cardiology

    pub_type: 临床试验,杂志文章,评审

    doi:10.1097/00001573-199605000-00008

    authors: Blitz A,Laks H

    更新日期:1996-05-01 00:00:00

  • Health benefits of physical activity: a systematic review of current systematic reviews.

    abstract:PURPOSE OF REVIEW:The health benefits of physical activity and exercise are clear; virtually everyone can benefit from becoming more physically active. Most international guidelines recommend a goal of 150 min/week of moderate-to-vigorous intensity physical activity. Many agencies have translated these recommendations ...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0000000000000437

    authors: Warburton DER,Bredin SSD

    更新日期:2017-09-01 00:00:00

  • The molecular genetics of congenital heart disease: a review of recent developments.

    abstract:PURPOSE OF REVIEW:Our understanding of the interactions of genes and pathways during heart development continues to expand with our knowledge of the genetic basis of congenital heart disease. Along with the discovery of specific genes that cause lesions, recent research has focused on the interactions of some previousl...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0b013e328337b4ce

    authors: Wolf M,Basson CT

    更新日期:2010-05-01 00:00:00

  • Advances in implantable cardioverter defibrillators.

    abstract::Implantable cardioverter defibrillators (ICDs) have become an important therapeutic modality for patients who have had a cardiac arrest or are at risk for life-threatening ventricular arrhythmias. Clinical trials have confirmed the role of the ICD for patients with sustained ventricular arrhythmias and have expanded t...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-200201000-00004

    authors: Swygman C,Wang PJ,Link MS,Homoud MK,Estes NA 3rd

    更新日期:2002-01-01 00:00:00

  • Unusual forms of ischemic heart disease.

    abstract::Unusual forms and causes of ischemic heart disease include angina pectoris in the presence of normal coronary arteries (syndrome X), congenital coronary abnormalities, vasculitic disorders, and graft atherosclerosis after cardiac transplantation. There is now evidence that endothelial dysfunction of coronary resistanc...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:

    authors: Drexler H,Schroeder JS

    更新日期:1994-07-01 00:00:00

  • Recent trends in infective endocarditis: influence of case definitions.

    abstract:PURPOSE OF REVIEW:Infective endocarditis continues to pose major challenges in diagnosis and management despite advances in understanding the epidemiology, microbiology, and pathology of the disease. The purpose of this article is to provide a review of diagnosis, microbiology, and treatment of infective endocarditis, ...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-200403000-00012

    authors: Devlin RK,Andrews MM,von Reyn CF

    更新日期:2004-03-01 00:00:00

  • The role of low-molecular-weight heparin in the management of acute coronary syndromes.

    abstract::Optimized medical treatment for the non-ST segment elevation acute coronary syndromes (NSTE ACS) should consist of a combined antithrombotic/anti-anginal regimen. Standard antithrombotic treatment is currently unfractionated heparin and aspirin, and in high-risk patients glycoprotein IIb/IIIa inhibitors. However, low-...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-200111000-00012

    authors: Cohen M

    更新日期:2001-11-01 00:00:00

  • Genetic testing in cardiovascular medicine: current landscape and future horizons.

    abstract:PURPOSE OF REVIEW:The number of clinically available genetic tests for heritable cardiovascular diseases has recently increased because of novel gene discoveries and advancements in DNA sequencing technologies. The purpose of this review is to provide up-to-date genetic testing information and guidance on how to incorp...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0b013e32835fb728

    authors: Sturm AC,Hershberger RE

    更新日期:2013-05-01 00:00:00

  • Coarctation of the aorta: evaluation and management.

    abstract:PURPOSE OF REVIEW:Coarctation of the aorta is the discrete narrowing of the proximal descending aorta and is the sixth most common lesion in congenital heart disease. Repair of the coarctation can relieve the obstruction, but recurrent coarctation and future aneurysm formation can occur, and a heightened risk of vascul...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0b013e328330cc22

    authors: Tanous D,Benson LN,Horlick EM

    更新日期:2009-11-01 00:00:00

  • New insights on renovascular hypertension.

    abstract::Although activation of the endocrine renin-angiotensin system with consequent vasoconstriction and salt retention have long been known as the hallmarks of the early phase of renovascular hypertension, the recent recognition of a local vascular angiotensin system and the understanding of the process of vascular remodel...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-199409000-00015

    authors: Ma AO,Gibbons GH

    更新日期:1994-09-01 00:00:00

  • New insights in preventive cardiology and cardiac rehabilitation.

    abstract:PURPOSE OF REVIEW:To summarize changing paradigms and perceptions in the prevention and treatment of cardiovascular disease. RECENT FINDINGS:Recent studies have shown that arterial inflammation probably plays a key role in the development and progression of atherosclerosis, that acute myocardial infarctions often evol...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0b013e32830b360b

    authors: Franklin BA,Trivax JE,Vanhecke TE

    更新日期:2008-09-01 00:00:00

  • Are statins diabetogenic?

    abstract:PURPOSE OF REVIEW:Statins are widely utilized for low-density lipoprotein lowering and for prevention of atherosclerotic cardiovascular disease. Although these drugs have a good safety record, increased risk of developing diabetes during extended use has recently garnered attention. Here we review clinical trial eviden...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0b013e3283470359

    authors: Sampson UK,Linton MF,Fazio S

    更新日期:2011-07-01 00:00:00

  • Biventricular pacing in congestive heart failure: a boost toward finer living.

    abstract::With 550,000 new cases each year, congestive heart failure is a major medical problem. Several medical therapies, including digoxin, angiotensin-converting enzyme inhibitors, and beta-blockers, have reduced the number of re-hospitalizations and slowed the progression of congestive heart failure. Angiotensin-converting...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-200201000-00014

    authors: Luck JC,Wolbrette DL,Boehmer JP,Ulsh PJ,Silber D,Naccarelli GV

    更新日期:2002-01-01 00:00:00

  • Drug therapy of chronic heart failure in the elderly: the current state of clinical-trial evidence.

    abstract:PURPOSE OF REVIEW:beta-Blockers, angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, aldosterone receptor antagonists, and digoxin are the most common drug classes used to treat chronic heart failure. We examine current clinical trial evidence concerning heart-failure management in the elderly. ...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/01.hco.0000231411.15049.20

    authors: Dulin BR,Krum H

    更新日期:2006-07-01 00:00:00

  • The pathogenesis of cardiac allograft vasculopathy.

    abstract::There has been an intensive effort in the past year to identify immunologic and nonimmunologic factors in the pathogenesis of cardiac allograft vasculopathy. Significant progress has been made regarding cell proliferation and cell death, with particular focus on cell growth factors, cell death factors, and their recep...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-199603000-00012

    authors: Dong C,Redenbach D,Wood S,Battistini B,Wilson JE,McManus BM

    更新日期:1996-03-01 00:00:00

  • Antithrombotic drugs in cardiovascular medicine: a year in review.

    abstract:PURPOSE OF REVIEW:To provide an up to date review of the most recent randomized clinical trials in the field of antithrombotic drugs for cardiovascular diseases. RECENT FINDINGS:In 2017, low-dose anti-Xa treatment added to aspirin proved to be more efficacious than either treatment alone in patients with stable athero...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0000000000000530

    authors: Ibrahim H,Rondina M,Welt FGP

    更新日期:2018-07-01 00:00:00

  • Will left-ventricular assist device therapy replace heart transplantation in the foreseeable future?

    abstract:PURPOSE OF REVIEW:Implantation of circulatory assist devices as a permanent alternative to heart transplantation, so-called Destination Therapy, has become a promising new option for treatment of patients with advanced heart failure who are not candidates for heart transplantation. RECENT FINDINGS:The landmark REMATCH...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/01.hco.0000153949.42189.03

    authors: Lietz K,Miller LW

    更新日期:2005-03-01 00:00:00

  • Pediatric cardiac catheterization.

    abstract::The publications of 2000 and 2001 stress how interventional pediatric cardiology has moved from angioplasty to device placement. This review summarizes the important articles during the past year that evaluated the safety and efficacy of atrial septal defect devices, patent ductus occluders, and stents to treat coarct...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-200205000-00013

    authors: Rocchini AP

    更新日期:2002-05-01 00:00:00