Abstract:
:There has been an intensive effort in the past year to identify immunologic and nonimmunologic factors in the pathogenesis of cardiac allograft vasculopathy. Significant progress has been made regarding cell proliferation and cell death, with particular focus on cell growth factors, cell death factors, and their receptors. Endothelial cell injury and endothelin expression and production have been implicated in the development of cardiac allograft vasculopathy. A significant clinical association between dyslipidemia and cardiac allograft vasculopathy has been detected by intracoronary ultrasonography. Furthermore, proteoglycans are postulated to play an important role through lipoprotein-proteoglycan interactions. The role of cytomegalovirus infection remains controversial. Immunosuppressive agents such as rapamycin and FK506 may contribute to a reduction of vasculopathy.
journal_name
Curr Opin Cardioljournal_title
Current opinion in cardiologyauthors
Dong C,Redenbach D,Wood S,Battistini B,Wilson JE,McManus BMdoi
10.1097/00001573-199603000-00012subject
Has Abstractpub_date
1996-03-01 00:00:00pages
183-90issue
2eissn
0268-4705issn
1531-7080journal_volume
11pub_type
杂志文章,评审abstract:PURPOSE OF REVIEW:C-reactive protein, a nonspecific marker of inflammation, has recently been proposed both as a marker of low-grade inflammation involved in atherogenesis and as a predictor of disease progression. RECENT FINDINGS:The physiologic functions of C-reactive protein as an anti-inflammatory scavenger molecu...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/01.hco.0000175518.57804.94
更新日期:2005-09-01 00:00:00
abstract:PURPOSE OF REVIEW:To evaluate whether long-term antiplatelet therapy may be effective and well tolerated. RECENT FINDINGS:Five important studies assessed the efficacy and safety of clopidogrel therapy in different settings. However, the problems concerning the duration of therapy are based substantially on the Clopido...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/01.hco.0000409964.20588.8c
更新日期:2011-12-01 00:00:00
abstract:PURPOSE OF REVIEW:A low level of plasma high density lipoprotein cholesterol (HDL-C) is a strong and independent risk factor for atherosclerotic cardiovascular disease (ASCVD). However, several large studies recently revealed that pharmacologic interventions that increase HDL-C concentration have not improved cardiovas...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000211
更新日期:2015-09-01 00:00:00
abstract::Coronary artery bypass surgery performed in patients with coronary artery disease and left ventricular dysfunction improves survival compared with antianginal therapy alone. The mechanisms for this survival advantage with revascularization therapy have not been systematically elucidated. Many of these patients have "h...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199607000-00008
更新日期:1996-07-01 00:00:00
abstract::Currently 14 million individuals in the United States have coronary disease. Within the next 2 decades, this number is expected to increase to 21 million persons. To minimize the excessive risk of recurrent cardiac events in these people, evidence-based, cost-effective prevention strategies must be developed. This rev...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199907000-00005
更新日期:1999-07-01 00:00:00
abstract:PURPOSE OF REVIEW:The aim of this review is to update the cardiovascular clinician on the current status of surgical therapies aimed at achieving reverse ventricular remodeling. RECENT FINDINGS:Relevant research focusing on mechanical options for reverse ventricular remodeling will be referenced and summarized. SUMMA...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/01.hco.0000221583.48748.d9
更新日期:2006-05-01 00:00:00
abstract::Recurrent episodes of unexplained syncope are among the most frequent of complaints referred to physicians for evaluation. Traditional methods of evaluation were both time consuming and expensive and left many patients without a diagnosis. Although neurocardiogenically mediated episodes of hypotension and bradycardia ...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199601000-00006
更新日期:1996-01-01 00:00:00
abstract::Ambulatory blood pressure monitoring is becoming increasingly popular in the diagnosis and treatment of patients with hypertensive disorders. Widespread clinical use, however, has been limited by a lack of normative data and prospective, controlled clinical studies of its impact on subsequent cardiovascular morbidity ...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199309000-00007
更新日期:1993-09-01 00:00:00
abstract::The focus of this review is the advantages of simultaneously assessing myocardial perfusion and left ventricular function. Nuclear cardiology imaging techniques as well as the development of technetium-labeled perfusion tracers now permit combined myocardial-perfusion and left-ventricular function studies at a single ...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199911000-00002
更新日期:1999-11-01 00:00:00
abstract::The normal myocardium is composed of a variety of cells: cardiac myocytes and noncardiomyocytes, which include endothelial and vascular smooth muscle cells and fibroblasts. Hypertensive heart disease involves a structural remodeling of muscular and nonmuscular compartments. It is not the quantity but rather the qualit...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-200007000-00010
更新日期:2000-07-01 00:00:00
abstract::Pulmonary edema is one of the most serious and life-threatening situations in emergency medicine. Lately it has become apparent that in most cases pulmonary edema is not caused by fluid accumulation but rather fluid redistribution that is directed into the lungs because of heart failure. Based on a series of recently ...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-200105000-00001
更新日期:2001-05-01 00:00:00
abstract:PURPOSE OF REVIEW:This article reviews the recent advances in stress echocardiography, with particular attention to articles published in 2010 and 2011. It summarizes the developments in the diagnostic and prognostic capabilities of stress echocardiography, discusses new data regarding the safety of stress echocardiogr...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0b013e328349035b
更新日期:2011-09-01 00:00:00
abstract:PURPOSE OF REVIEW:The aim of this article is to review the current status of optimal revascularization strategies in patients presenting with multivessel coronary artery disease. RECENT FINDINGS:Coronary artery bypass surgery is the gold standard for patients with multivessel disease. Recent developments in the interv...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/01.hco.0000245738.40088.70
更新日期:2006-11-01 00:00:00
abstract:PURPOSE OF REVIEW:To review current controversies in the transcatheter device closure of ostium secundum atrial septal defects (ASD). RECENT FINDINGS:Transcatheter device closure of ASD (TC-ASD) has well established efficacy and safety. For most individual patients with suitable anatomy, TC-ASD is the preferred method...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000476
更新日期:2018-01-01 00:00:00
abstract::Primary cardiac tumors are rare clinical entities. Benign tumors are often amenable to surgical excision, whereas malignant tumors are seldom resectable. The literature has reported that 28 patients have undergone orthotopic heart transplantation for inoperable primary cardiac tumors. The results of these transplants ...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-200003000-00010
更新日期:2000-03-01 00:00:00
abstract:PURPOSE OF REVIEW:The number of clinically available genetic tests for heritable cardiovascular diseases has recently increased because of novel gene discoveries and advancements in DNA sequencing technologies. The purpose of this review is to provide up-to-date genetic testing information and guidance on how to incorp...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0b013e32835fb728
更新日期:2013-05-01 00:00:00
abstract::The publications of 2000 and 2001 stress how interventional pediatric cardiology has moved from angioplasty to device placement. This review summarizes the important articles during the past year that evaluated the safety and efficacy of atrial septal defect devices, patent ductus occluders, and stents to treat coarct...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-200205000-00013
更新日期:2002-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Cardiovascular implantable electronic devices are widely used to treat symptomatic arrhythmias, prevent sudden cardiac death, and improve symptoms and cardiac function. Continued population growth and expanding indications have resulted in a progressive increase in the number of cardiovascular implant...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000247
更新日期:2016-01-01 00:00:00
abstract:PURPOSE OF REVIEW:In the era of percutaneous coronary intervention, surgeons are confronted with performing coronary artery bypass graft surgery on patients with previous balloon dilatation or stenting. This review evaluates the impact of previous percutaneous coronary intervention on patient survival and choice of opt...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0b013e3282f0795d
更新日期:2007-11-01 00:00:00
abstract::The increased use of arterial conduits in coronary artery bypass grafting is reflected in numerous publications addressing indications, choice of conduits, and possible side-effects. Besides the internal thoracic artery, the right gastroepiploic artery is becoming established, and the inferior epigastric artery is be...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199311000-00004
更新日期:1993-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Carotid endarterectomy (CEA) is still considered the gold standard in the treatment of patients with significant carotid stenosis and has proven its value over the past decades. Endovascular techniques have evolved, and carotid artery stenting (CAS) is challenging CEA to become the better treatment. V...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0b013e328330c302
更新日期:2009-11-01 00:00:00
abstract::Minimally invasive cardiac surgery has evolved in response to the intrinsic irony facing cardiac surgeons: that we must injure our patients to treat them. In recent years, advances in fiberoptic imaging technology, applied to other surgical specialties, suggested the possibility that cardiac surgery might also be perf...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199901000-00011
更新日期:1999-01-01 00:00:00
abstract:PURPOSE OF REVIEW:To describe recent advancements in cardiovascular genetics made possible by leveraging next-generation sequencing (NGS), and to provide a framework for practical applications of genetic testing for hypertrophic (HCM), dilated (DCM), and arrhythmogenic right ventricular cardiomyopathies (ARVC). RECENT...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000512
更新日期:2018-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Cardiac transplantation is a recognized therapy for end-stage heart failure. Graft coronary artery disease is a chief determinant of long-term survival following cardiac transplantation. There are multiple purported etiologies for graft coronary artery disease including both immunologic and nonimmunol...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/01.hco.0000203184.89158.16
更新日期:2006-03-01 00:00:00
abstract:PURPOSE OF REVIEW:The aim of this review is to focus specifically on the indications, evolution of technique, and results of surgical ablation for atrial fibrillation. RECENT FINDINGS:With the introduction of the Cox-Maze IV procedure utilizing bipolar radiofrequency ablation and cryoablation, long-term studies have d...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000125
更新日期:2015-01-01 00:00:00
abstract:PURPOSE OF REVIEW:The natural history of cardiogenic shock has improved significantly with the utilization of revascularization and mechanical circulatory support. Despite the interest in identifying new pharmacological agents, the medical therapy to restore perfusion is limited by their side-effects and no solid evide...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/HCO.0000000000000057
更新日期:2014-05-01 00:00:00
abstract::The explosion of high-resolution imaging technology in recent years has led to the increasing problem of choosing imaging modalities appropriate to specific clinical questions. In terms of structural information, for example, the relative benefits of ultrasound versus magnetic resonance imaging versus computed tomogr...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199212000-00015
更新日期:1992-12-01 00:00:00
abstract:PURPOSE OF REVIEW:Cardiac resynchronization therapy (CRT) reduces morbidity and mortality in patients with mild-to-severe heart failure. However, up to 40% of CRT recipients are nonresponders. This review addresses important aspects with regard to the identification and management of CRT nonresponders. RECENT FINDINGS...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,meta分析,评审
doi:10.1097/HCO.0000000000000140
更新日期:2015-01-01 00:00:00
abstract::Recent epidemiologic studies of the risk factors for early and late phases of transplant coronary artery disease (TxCAD) have identified metabolic abnormalities such as hyperlipidemia and insulin resistance as important risk factors, independent of rejection. In randomized trials, calcium channel blockers and hydroxym...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199803000-00007
更新日期:1998-03-01 00:00:00
abstract::Endocarditis remains a major worldwide problem despite significant advances in diagnostic and therapeutic interventions. This review centers on the recent studies that have been published in the past year concerning the epidemiologic, diagnostic, and therapeutic aspects of infective and noninfective endocarditis in bo...
journal_title:Current opinion in cardiology
pub_type: 杂志文章,评审
doi:10.1097/00001573-199703000-00006
更新日期:1997-03-01 00:00:00