Fibrosis and hypertensive heart disease.

abstract：PURPOSE OF REVIEW:Despite numerous advances in coronary interventional techniques, the frequent occurrence of restenosis continues to plague interventional cardiology. With the widespread use of drug-eluting stents, there is a need to reexamine critically the roles of the various interventional techniques currently ava...

journal_title：Current opinion in cardiology

authors： Karthikeyan G,Bhargava B

更新日期：2004-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Truncating variants in the TTN gene (TTNtv) are frequently identified in patients with dilated cardiomyopathy (DCM) but are also present in apparently healthy people in the general population. Consequently, there is considerable uncertainty about what it means for any single individual if a TTNtv is f...

journal_title：Current opinion in cardiology

authors： Fatkin D,Huttner IG

更新日期：2017-05-01 00:00:00

abstract：:Hypertrophic cardiomyopathy has been shown to be a genetically heterogeneous disorder, linked to at least four different loci on chromosomes 14, 1, 15, and 11. Thus far, three genes have been identified that harbor mutations leading to hypertrophic cardiomyopathy. These genes--cardiac beta myosin heavy chain, alpha tr...

journal_title：Current opinion in cardiology

authors： Elstein E

更新日期：1995-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The intra-aortic balloon pump (IABP) has been used as a cardiac assist device in various clinical situations since 1968 on the basis of the physiological principles and observational data, with little randomized data until recently. RECENT FINDINGS:Recently published randomized controlled trials (RCT...

journal_title：Current opinion in cardiology

authors： Ihdayhid AR,Chopra S,Rankin J

更新日期：2014-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Transcatheter aortic-valve implantation is a promising new treatment modality for patients with aortic-valve disease, where it may revolutionize the treatment of elderly and high-risk patients. RECENT FINDINGS:The two devices currently available, the Edwards Sapien valve and the Medtronic CoreValve s...

journal_title：Current opinion in cardiology

authors： Ruel M,Labinaz M

更新日期：2010-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Coronary artery disease is common in patients with end-stage renal disease (ESRD) on hemodialysis. ESRD patients are prone to atherosclerosis and are likely to present with advanced CAD requiring coronary artery bypass graft surgery (CABG) or percutaneous coronary intervention (PCI). RECENT FINDINGS:...

journal_title：Current opinion in cardiology

authors： Karkhanis R,Tam DY,Fremes SE

更新日期：2018-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Lifestyle counseling that includes exercise training, diet modification, and medication adherence is critical to hypertension management. This article summarizes the efficacy of lifestyle counseling interventions in face-to-face, telehealth, and e-counseling settings. It also discusses the therapeutic...

journal_title：Current opinion in cardiology

authors： Nolan RP,Liu S,Payne AY

更新日期：2014-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Although antiplatelet agents are frequently prescribed to patients with lower extremity peripheral artery disease (PAD), there is an overall lack of consensus among published evidence and guidelines with respect to this practice. RECENT FINDINGS:Antiplatelet agents are prescribed to patients with PAD...

journal_title：Current opinion in cardiology

authors： Banerjee S,Sarode K,Vinas A,Banerjee A,Mohammad A,Brilakis ES

更新日期：2015-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The review is designed to outline the major developments in genetic testing in the cardiovascular arena in the past year or so. This is an exciting time in genetic testing as whole exome and whole genome approaches finally reach the clinic. These new approaches offer insight into disease causation in ...

journal_title：Current opinion in cardiology

authors： Arndt AK,MacRae CA

更新日期：2014-05-01 00:00:00

abstract：PURPOSE OF REVIEW:This article is an update on DiGeorge syndrome research focusing on the synergy of human and model systems genetics toward the understanding of conotruncal and aortic arch defects. RECENT FINDINGS:The identification of mutations of the human T-Box1 (TBX1) gene and progress on research of Tbx1 functio...

journal_title：Current opinion in cardiology

authors： Baldini A

更新日期：2004-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Heart failure is a major chronic illness with no definitive cure. With improving healthcare and with an aging population in many countries, heart failure has become a common disease of the elderly. Pharmacological management of heart failure in the elderly remains a challenge. The syndrome of heart fa...

journal_title：Current opinion in cardiology

authors： Alghamdi F,Chan M

更新日期：2017-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Heart failure is a worldwide epidemic. Aggressive treatment of patients at risk for heart failure is important. There are no trials targeting primary prevention of heart failure. However, there is trial data demonstrating that treatment of patients with atherosclerotic vascular disease, hypertension, ...

journal_title：Current opinion in cardiology

authors： Dupree CS

更新日期：2009-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitors are promising therapies that inhibit the degradation of low-density lipoprotein (LDL) receptors in the hepatocyte and thus increase LDL cholesterol (LDL-C) uptake from the blood. This review summarizes main findings in the field of PCSK9...

journal_title：Current opinion in cardiology

authors： Eisen A,Giugliano RP

更新日期：2016-11-01 00:00:00

abstract：PURPOSE OF REVIEW:This review aims to summarize recent reports on percutaneous coronary intervention (PCI) strategies for patients with ST-elevation myocardial infarction (STEMI) and multivessel coronary artery disease (CAD). RECENT FINDINGS:Recent randomized clinical trials and meta-analyses have suggested that patie...

journal_title：Current opinion in cardiology

authors： Thomas MP,Bates ER

更新日期：2017-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The current review focuses on new trends in genome-wide assessment of the inherited component of blood pressure variation. RECENT FINDINGS:Systematic linkage and association analyses of a region on chromosome 1q, complemented by gene prioritization with comparative genomic evidence, revealed variants...

journal_title：Current opinion in cardiology

authors： Hamet P,Seda O

更新日期：2007-07-01 00:00:00

abstract：PURPOSE OF REVIEW:This review demonstrates the need for enhancing strategic approaches to the prevention and control of hypertension, a global health issue. RECENT FINDINGS:An epidemic of chronic noncommunicable diseases is threatening national healthcare systems' sustainability and the economy of many countries. Incr...

journal_title：Current opinion in cardiology

authors： Campbell NR,Niebylski ML,World Hypertension League Executive.

更新日期：2014-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Atrial fibrillation is the most common sustained cardiac arrhythmia and may cause significant morbidity. Current management strategies offer only modest success and may be associated with intolerable drug side effects or risk of procedural complications. As with other cardiac arrhythmias, the identifi...

journal_title：Current opinion in cardiology

authors： Gollob MH

更新日期：2006-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Cardiac transplantation is a recognized therapy for end-stage heart failure. Graft coronary artery disease is a chief determinant of long-term survival following cardiac transplantation. There are multiple purported etiologies for graft coronary artery disease including both immunologic and nonimmunol...

journal_title：Current opinion in cardiology

authors： Kass M,Haddad H

更新日期：2006-03-01 00:00:00

abstract：:As a result of the increasing size of waiting lists and lengthening of waiting times for heart transplantation, coronary revascularization has emerged as an important therapeutic option in the management of patients with ischemic cardiomyopathy. A critical challenge is the identification of candidates with regions of ...

journal_title：Current opinion in cardiology

authors： Blitz A,Laks H

更新日期：1996-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Maximalist low-density lipoprotein (LDL)-lowering strategies such as lowering LDL as much as possible or, alternatively, using the most potent LDL-lowering regimens have become increasingly popular. Almost all attention has focused on the potential advantages of these approaches with little focus on t...

journal_title：Current opinion in cardiology

authors： Sniderman AD,De Graaf J,Couture P

更新日期：2012-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Diagnostic testing using noninvasive imaging has become an integral part of risk stratification in patients with coronary artery disease. It is important to understand the integral strengths and weaknesses between the different modalities of stress testing and to apply accurately the type of test the ...

journal_title：Current opinion in cardiology

authors： Maganti K,Rigolin VH

更新日期：2003-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The emerging role of stress and particularly exercise echocardiography in mitral regurgitation has been recently emphasized. In fact, the evaluation of mitral regurgitation only under resting conditions might underestimate the full impact of the lesion and its clinical effects. RECENT FINDINGS:Exerci...

journal_title：Current opinion in cardiology

authors： Lancellotti P,Magne J

更新日期：2012-09-01 00:00:00

abstract：PURPOSE OF REVIEW:C-reactive protein, a nonspecific marker of inflammation, has recently been proposed both as a marker of low-grade inflammation involved in atherogenesis and as a predictor of disease progression. RECENT FINDINGS:The physiologic functions of C-reactive protein as an anti-inflammatory scavenger molecu...

journal_title：Current opinion in cardiology

authors： Sepulveda JL,Mehta JL

更新日期：2005-09-01 00:00:00

abstract：:Cardiopulmonary bypass triggers a generalized inflammatory response that is largely mediated by activation of polymorphonuclear neutrophils, their adhesion to endothelial cells, and the subsequent release of cytotoxic products. It has been known for several years that the inflammatory response to extracorporeal circul...

journal_title：Current opinion in cardiology

authors： Menasché P

更新日期：1995-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Health professionals are presented with the challenge of prescribing physical activity that is likely to be sustained by the sedentary majority. Walking is eminently suited to physical activity prescription for inactive individuals as it is accessible to men and women of all ages and social groups and...

journal_title：Current opinion in cardiology

authors： Murtagh EM,Murphy MH,Boone-Heinonen J

更新日期：2010-09-01 00:00:00

abstract：:Intravenous thrombolysis has become a primary mode of reperfusion therapy for selected patients with acute myocardial infarction. The timing and potential benefits of cardiac angiography and coronary revascularization after thrombolysis in patients experiencing an uncomplicated myocardial infarction have been extensiv...

journal_title：Current opinion in cardiology

authors： Aguirre FV,Merritt RF,Carollo SC

更新日期：1995-07-01 00:00:00

abstract：:Indications for cardiac catheterization--including coronary angiography--have substantially broadened with the advent of nonsurgical therapeutic interventions performed in the catheterization laboratory. Consequently, the increasing number of facilities performing these procedures require clear and unmistakable guidel...

journal_title：Current opinion in cardiology

authors： Rafflenbeul W,Riedel M

更新日期：1993-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The possible role of several neurohormonal factors in pathogenesis of hypertension has been studied extensively both in humans and in experimental animal models. However, controversial data from some previous studies are indecisive and call for reassessment and development of new targets. This mini-re...

journal_title：Current opinion in cardiology

authors： Wang DH

更新日期：2008-07-01 00:00:00

abstract：:Although it has been the topic of intense medical and surgical attention for over 20 years, the coexistence of severe carotid artery disease in patients undergoing coronary artery bypass graft continues to be a major cause of perioperative morbidity and mortality. Refinements in diagnostic modalities, mainly by duplex...

journal_title：Current opinion in cardiology

authors： Schepens MA,Vermeulen FE

更新日期：1996-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The role of cardiac catheterization in pediatric cardiology has changed significantly in the past 10-15 years. As interventional procedures dominate the field, it is important to examine the recent advances in non-interventional pediatric cardiac catheterization. RECENT FINDINGS:Meaningful and accura...

journal_title：Current opinion in cardiology

authors： Kanter JP,Hellenbrand WE

更新日期：2005-03-01 00:00:00