Advances in the field of proprotein convertase subtilisin kexin type 9 inhibitors.

abstract：PURPOSE OF REVIEW:The emerging role of stress and particularly exercise echocardiography in mitral regurgitation has been recently emphasized. In fact, the evaluation of mitral regurgitation only under resting conditions might underestimate the full impact of the lesion and its clinical effects. RECENT FINDINGS:Exerci...

journal_title：Current opinion in cardiology

authors： Lancellotti P,Magne J

更新日期：2012-09-01 00:00:00

abstract：:Cardiovascular disease is the leading cause of death world-wide in populations older than 65 years of age. The variation in cardiovascular mortality rates in this population indicates a substantial potential for effective coronary prevention. The highest risk for development of coronary heart disease is in individuals...

journal_title：Current opinion in cardiology

authors： Wenger NK

更新日期：1997-03-01 00:00:00

abstract：:Recent epidemiologic studies of the risk factors for early and late phases of transplant coronary artery disease (TxCAD) have identified metabolic abnormalities such as hyperlipidemia and insulin resistance as important risk factors, independent of rejection. In randomized trials, calcium channel blockers and hydroxym...

journal_title：Current opinion in cardiology

authors： Valantine-von Kaeppler HA

更新日期：1998-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Bleeding has recently been identified as a major adverse outcome in patients with acute coronary syndromes. In this review, the importance of the association of bleeding with mortality and strategies to reduce bleeding with percutaneous coronary intervention are discussed. RECENT FINDINGS:Nine trials...

journal_title：Current opinion in cardiology

authors： White HD

更新日期：2009-07-01 00:00:00

abstract：:In reviewing selected publications on congenital heart disease management for 1990 and 1991, some topics have been chosen for discussion, including isolated patent ductus arteriosus, coarctation of the aorta, critical aortic stenosis in early infancy, hypoplastic left-heart syndrome, pulmonary artery banding, Fontan p...

journal_title：Current opinion in cardiology

authors： Mee RB

更新日期：1992-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an up to date review of the most recent randomized clinical trials in the field of antithrombotic drugs for cardiovascular diseases. RECENT FINDINGS:In 2017, low-dose anti-Xa treatment added to aspirin proved to be more efficacious than either treatment alone in patients with stable athero...

journal_title：Current opinion in cardiology

authors： Ibrahim H,Rondina M,Welt FGP

更新日期：2018-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Body habitus is a key lifestyle characteristic whose current status and future projections are disconcerting. The percentage of the global population who are either overweight or obese has substantially increased, with no indication that any country has a solution to this issue. Hypertension is a key ...

journal_title：Current opinion in cardiology

authors： Arena R,Daugherty J,Bond S,Lavie CJ,Phillips S,Borghi-Silva A

更新日期：2016-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Diagnostic testing using noninvasive imaging has become an integral part of risk stratification in patients with coronary artery disease. It is important to understand the integral strengths and weaknesses between the different modalities of stress testing and to apply accurately the type of test the ...

journal_title：Current opinion in cardiology

authors： Maganti K,Rigolin VH

更新日期：2003-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Resistant hypertension is defined as blood pressure above patient goal despite three different antihypertensive agents at optimal dose including a diuretic. Resistant hypertension is increasingly common issue in clinical practice and it is a major risk factor of cardiovascular disease. RECENT FINDING...

journal_title：Current opinion in cardiology

authors： Hasan MA,Stewart MH,Lavie CJ,Ventura HO

更新日期：2019-07-01 00:00:00

abstract：PURPOSE OF REVIEW:In the era of percutaneous coronary intervention, surgeons are confronted with performing coronary artery bypass graft surgery on patients with previous balloon dilatation or stenting. This review evaluates the impact of previous percutaneous coronary intervention on patient survival and choice of opt...

journal_title：Current opinion in cardiology

authors： Al-Attar N,Nataf P

更新日期：2007-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide a broad overview of the current state of knowledge of coronary artery bypass grafting with bilateral internal thoracic artery (BITA). RECENT FINDINGS:There exists a large body of literature from mostly observational studies supporting the use of BITA in patients undergoing coronary artery ...

journal_title：Current opinion in cardiology

authors： Yanagawa B,Verma S,Puskas JD

更新日期：2017-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Truncating variants in the TTN gene (TTNtv) are frequently identified in patients with dilated cardiomyopathy (DCM) but are also present in apparently healthy people in the general population. Consequently, there is considerable uncertainty about what it means for any single individual if a TTNtv is f...

journal_title：Current opinion in cardiology

authors： Fatkin D,Huttner IG

更新日期：2017-05-01 00:00:00

abstract：:Optimized medical treatment for the non-ST segment elevation acute coronary syndromes (NSTE ACS) should consist of a combined antithrombotic/anti-anginal regimen. Standard antithrombotic treatment is currently unfractionated heparin and aspirin, and in high-risk patients glycoprotein IIb/IIIa inhibitors. However, low-...

journal_title：Current opinion in cardiology

authors： Cohen M

更新日期：2001-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the electrophysiological profile and the clinical portfolio of dronedarone, a new multichannel-blocking antiarrhythmic drug developed for the treatment of atrial fibrillation. RECENT FINDINGS:Dronedarone is a derivative of amiodarone that is free of iodine and less lipophilic. The drug ha...

journal_title：Current opinion in cardiology

authors： Duray GZ,Ehrlich JR,Hohnloser SH

更新日期：2010-01-01 00:00:00

abstract：:Assessment of the pulmonary circulation and right ventricular function is a cornerstone in the evaluation of the patient as a potential heart transplant recipient. The importance of pulmonary hypertension is linked to outcomes in the posttransplant period. Preoperative pulmonary vascular resistance is an independent r...

journal_title：Current opinion in cardiology

authors： Natale ME,Piña IL

更新日期：2003-03-01 00:00:00

abstract：:Recurrent episodes of unexplained syncope are among the most frequent of complaints referred to physicians for evaluation. Traditional methods of evaluation were both time consuming and expensive and left many patients without a diagnosis. Although neurocardiogenically mediated episodes of hypotension and bradycardia ...

journal_title：Current opinion in cardiology

authors： Grubb BP,Kosinski D

更新日期：1996-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Vascular disease often affects more than one territory. Atherosclerosis is a global disease affecting multiple organs/systems. Cardiovascular risk factors are associated with an increased risk for the development of arterial disease in all vascular beds but differ in their individual impacts for each ...

journal_title：Current opinion in cardiology

authors： Paraskevas KI,Geroulakos G,Veith FJ,Mikhailidis DP

更新日期：2020-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Cardiovascular implantable electronic devices are widely used to treat symptomatic arrhythmias, prevent sudden cardiac death, and improve symptoms and cardiac function. Continued population growth and expanding indications have resulted in a progressive increase in the number of cardiovascular implant...

journal_title：Current opinion in cardiology

authors： Sadek MM,Goldstein W,Epstein AE,Schaller RD

更新日期：2016-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Dyslipidaemias are noted in all stages of chronic kidney disease (CKD). Currently most evidence for their treatment comes from secondary retrospective analyses of patient subgroups with CKD recruited into clinical trials powered of hypertensive and dyslipideamic cohorts powered for cardiovascular endp...

journal_title：Current opinion in cardiology

authors： Jenkins M,Goldsmith D

更新日期：2012-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To review trends in practice for mitral valve surgery in the US over the past decade. RECENT FINDINGS:Advances in the understanding of mitral valve pathophysiology and the technology involved with mitral valve surgery have led to significant changes of the current practice for mitral valve surgery, w...

journal_title：Current opinion in cardiology

authors： Ad N,Barnett SD,Speir AM,Massimiano PS

更新日期：2008-03-01 00:00:00

abstract：:In the past 2 years, significant advances have been made in class III antiarrhythmic drug therapy. In patients with ventricular arrhythmias and implantable cardioverter defibrillators (ICDs), antiarrhythmic agents are increasingly being used as adjunct therapy to decrease the frequency of ICD discharges. Sotalol was r...

journal_title：Current opinion in cardiology

authors： Sager PT

更新日期：2000-01-01 00:00:00

abstract：PURPOSE OF REVIEW:beta-Blockers, angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, aldosterone receptor antagonists, and digoxin are the most common drug classes used to treat chronic heart failure. We examine current clinical trial evidence concerning heart-failure management in the elderly. ...

journal_title：Current opinion in cardiology

authors： Dulin BR,Krum H

更新日期：2006-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Open aortic arch surgery is highly invasive and may result in significant morbidity. Recent innovations in thoracic stent-graft technology have facilitated methods of replacing the aortic arch without deep hypothermic circulatory arrest or even cardiopulmonary bypass. We present a review of the curren...

journal_title：Current opinion in cardiology

authors： Desai ND,Szeto WY

更新日期：2009-11-01 00:00:00

abstract：PURPOSE OF REVIEW:This review examines the application of next-generation sequencing (NGS) technologies in the identification of the causation of nonsyndromic genetic cardiomyopathies. RECENT FINDINGS:NGS sequencing of the entire genetic coding sequence (the exome) has successfully identified five novel genes and caus...

journal_title：Current opinion in cardiology

authors： Norton N,Li D,Hershberger RE

更新日期：2012-05-01 00:00:00

abstract：:The COCPIT study, performed in a complete national cohort of adult patients consecutively listed for cardiac transplantation in Germany in 1997, found a beneficial effect only in the group that was at high risk of dying from heart failure without transplantation. If these results can be reproduced in other countries, ...

journal_title：Current opinion in cardiology

authors： Deng MC,Smits JM,De Meester J,Hummel M,Schoendube F,Scheld HH

更新日期：2001-03-01 00:00:00

abstract：:Angiogenesis, the de novo formation of new vasculature, is a critical response to ischemia that provides neovascularization of ischemic tissues. In therapeutic angiogenesis, an angiogen--a mediator that induces angiogenesis--is delivered to targeted tissues, augmenting the native angiogenic process and enhancing reper...

journal_title：Current opinion in cardiology

authors： Hamawy AH,Lee LY,Crystal RG,Rosengart TK

更新日期：1999-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to describe the effects of mechanical circulatory support (MCS) on changes in kidney function and their relationship with mortality, with an additional focus on the evaluation and management of both preimplant and post-MCS renal dysfunction. RECENT FINDINGS:Renal dysfunc...

journal_title：Current opinion in cardiology

authors： Brisco MA,Testani JM,Cook JL

更新日期：2016-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Statins significantly reduce cardiovascular morbidity and mortality in patients with and without coronary heart disease. Recently, much debate has focused on use of statins for primary prevention following a class-wide safety label change by the US Food and Drug Administration amidst concerns of worse...

journal_title：Current opinion in cardiology

authors： Minder CM,Blumenthal RS,Blaha MJ

更新日期：2013-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Coronary subclavian steal syndrome (CSSS) is the reversal of blood flow in an internal mammary artery bypass graft that results in coronary ischemia. CSSS is an uncommon but treatable cause of coronary ischemia. In this review, we highlight the historical background and epidemiology of CSSS, common cl...

journal_title：Current opinion in cardiology

authors： Sintek M,Coverstone E,Singh J

更新日期：2014-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Low cholesterol syndromes were considered curiosities. The present article reviews some hypolipidaemic disorders and the drugs developed from the insights they provided. RECENT FINDINGS:Abetalipopoproteinaemia and hypobetalipoproteinaemia are associated with low cholesterol concentrations and caused ...

journal_title：Current opinion in cardiology

authors： Handhle A,Viljoen A,Ramachandran R,Wierzbicki AS

更新日期：2020-07-01 00:00:00