Sex differences in hypertrophic cardiomyopathy: new insights.

abstract：:Pathogenesis of familial inherited arrhythmias is being progressively clarified thanks to the insights provided by molecular biology and by functional studies. Transmembrane or intracellular ion channel mutations have been identified in genetically determined forms of polymorphic ventricular tachycardia and sudden dea...

journal_title：Current opinion in cardiology

authors： Napolitano C,Priori SG

更新日期：2002-05-01 00:00:00

abstract：:Increased carotid intima media thickness (IMT) is relatively simple, inexpensive, and reproducible noninvasive marker of global atherosclerotic disease. It is a frequently used experimental tool in epidemiologic studies to identify and follow cardiovascular disease. There is evidence that early detection of atheroscle...

journal_title：Current opinion in cardiology

authors： Sinha AK,Eigenbrodt M,Mehta JL

更新日期：2002-09-01 00:00:00

abstract：PURPOSE OF REVIEW:There is controversy regarding the optimal choice of prosthetic valves in patients less than 65 years of age requiring mitral valve replacement (MVR). Recently, trends for valve replacement are moving towards biological prosthesis also in younger patients, which is justified by the fact that a later v...

journal_title：Current opinion in cardiology

authors： Reineke DC,Heinisch PP,Winkler B,Englberger L,Carrel TP

更新日期：2015-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The appropriate treatment of patients with acute pulmonary embolism who present with right ventricular dysfunction but normal arterial blood pressure, and particularly the potential benefits of thrombolytic treatment in this setting, continue to be highly controversial. In the past year, several well ...

journal_title：Current opinion in cardiology

authors： Konstantinides S

更新日期：2005-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Viability assessment has a key role in the management of patients with ischemic heart disease. Positron emission tomography (PET) is a unique modality that evaluates myocardial viability via assessing the tissues metabolic and perfusion properties. The mainstay of metabolic imaging relies on glucose m...

journal_title：Current opinion in cardiology

authors： Khalaf S,Chamsi-Pasha M,Al-Mallah MH

更新日期：2019-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Thrombus formation, usually on a ruptured atherosclerotic plaque, is pivotal in the pathogenesis of ST segment elevation myocardial infarction (STEMI). This thrombus formation provides the milieu for re-occlusion of the infarct-related artery, the main location of re-infarction post-STEMI. Although ra...

journal_title：Current opinion in cardiology

authors： French JK,Burgess S,Chew DP

更新日期：2015-07-01 00:00:00

abstract：PURPOSE OF REVIEW:beta-Blockers, angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, aldosterone receptor antagonists, and digoxin are the most common drug classes used to treat chronic heart failure. We examine current clinical trial evidence concerning heart-failure management in the elderly. ...

journal_title：Current opinion in cardiology

authors： Dulin BR,Krum H

更新日期：2006-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Cardiovascular and metabolic diseases are closely linked and commonly occur in the same patients. This review focuses on the cyclic guanosine monophosphate (cGMP) system and its crosstalk between metabolism and the cardiovascular system. RECENT FINDINGS:Recent studies suggest that cGMP, which serves ...

journal_title：Current opinion in cardiology

authors： Jordan J,Hildebrand S,Pfeifer A

更新日期：2019-07-01 00:00:00

abstract：PURPOSE OF REVIEW:On the very solid background of experimental and clinical studies pointing to the cardiovascular risks associated with depressed vagal reflexes and supported by specific experiments in animal models of heart failure, we are witnessing a rapidly growing interest in the very untraditional approach to th...

journal_title：Current opinion in cardiology

authors： Schwartz PJ

更新日期：2011-01-01 00:00:00

abstract：:Acute mesenteric ischemia (AMI) remains a complex and difficult clinical problem. Such acute ischemia is usually either embolic or thrombotic in nature, but other etiologies exist. The diagnosis of AMI is difficult to establish and often delayed, resulting in irreversible bowel injury that requires intestinal resectio...

journal_title：Current opinion in cardiology

authors： Vicente DC,Kazmers A

更新日期：1999-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The emerging role of stress and particularly exercise echocardiography in mitral regurgitation has been recently emphasized. In fact, the evaluation of mitral regurgitation only under resting conditions might underestimate the full impact of the lesion and its clinical effects. RECENT FINDINGS:Exerci...

journal_title：Current opinion in cardiology

authors： Lancellotti P,Magne J

更新日期：2012-09-01 00:00:00

abstract：:In the past 2 years, significant advances have been made in class III antiarrhythmic drug therapy. In patients with ventricular arrhythmias and implantable cardioverter defibrillators (ICDs), antiarrhythmic agents are increasingly being used as adjunct therapy to decrease the frequency of ICD discharges. Sotalol was r...

journal_title：Current opinion in cardiology

authors： Sager PT

更新日期：2000-01-01 00:00:00

abstract：:The introduction of new drugs, and a re-evaluation of older drugs, have radically changed the pharmacological management of heart failure. Angiotensin converting enzyme (ACE) inhibitors, digitalis, diuretics and the combination of nitrates and hydralazine are now used. The first Cooperative North Scandinavian Enalapri...

journal_title：Current opinion in cardiology

authors： Giles TD

更新日期：1994-07-01 00:00:00

abstract：:Although it has been the topic of intense medical and surgical attention for over 20 years, the coexistence of severe carotid artery disease in patients undergoing coronary artery bypass graft continues to be a major cause of perioperative morbidity and mortality. Refinements in diagnostic modalities, mainly by duplex...

journal_title：Current opinion in cardiology

authors： Schepens MA,Vermeulen FE

更新日期：1996-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite numerous advances in coronary interventional techniques, the frequent occurrence of restenosis continues to plague interventional cardiology. With the widespread use of drug-eluting stents, there is a need to reexamine critically the roles of the various interventional techniques currently ava...

journal_title：Current opinion in cardiology

authors： Karthikeyan G,Bhargava B

更新日期：2004-09-01 00:00:00

abstract：:Recent epidemiologic studies of the risk factors for early and late phases of transplant coronary artery disease (TxCAD) have identified metabolic abnormalities such as hyperlipidemia and insulin resistance as important risk factors, independent of rejection. In randomized trials, calcium channel blockers and hydroxym...

journal_title：Current opinion in cardiology

authors： Valantine-von Kaeppler HA

更新日期：1998-03-01 00:00:00

abstract：:Recurrent episodes of unexplained syncope are among the most frequent of complaints referred to physicians for evaluation. Traditional methods of evaluation were both time consuming and expensive and left many patients without a diagnosis. Although neurocardiogenically mediated episodes of hypotension and bradycardia ...

journal_title：Current opinion in cardiology

authors： Grubb BP,Kosinski D

更新日期：1996-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The possible role of several neurohormonal factors in pathogenesis of hypertension has been studied extensively both in humans and in experimental animal models. However, controversial data from some previous studies are indecisive and call for reassessment and development of new targets. This mini-re...

journal_title：Current opinion in cardiology

authors： Wang DH

更新日期：2008-07-01 00:00:00

abstract：:Large databases are being used for outcome prediction analysis with increasing frequency. This review examines four separate databases used to provide risk analysis in the cardiac surgery population. Populations in the databases range in size from 3500 to over 116,000 patients. All of the databases were applied on ...

journal_title：Current opinion in cardiology

authors： Park SE,Cmolik BL,Clark RE

更新日期：1992-04-01 00:00:00

abstract：:Hypertrophic cardiomyopathy is a primary myocardial disorder with an autosomal pattern of inheritance, characterized by asymmetric left ventricular hypertrophy with myocyte and myofibrillar disarray. Approximately 30% to 50% of all cases are accounted for by mutations in the beta-cardiac myosin heavy chain gene on chr...

journal_title：Current opinion in cardiology

authors： Vassalli G,Seiler C,Hess OM

更新日期：1994-05-01 00:00:00

abstract：PURPOSE OF REVIEW:With wider indications for implantable cardioverter defibrillator therapy, more patients at lower risk for ventricular tachyarrhythmia receive this treatment. To maintain the ratio of benefit versus side-effects at an acceptable level, the risk of inappropriate implantable cardioverter defibrillator t...

journal_title：Current opinion in cardiology

authors： Israel CW

更新日期：2008-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To compare the potential of high-density lipoprotein (HDL) cholesterol and apolipoprotein (apo) A-I, the major protein in HDL particles, in predicting cardiovascular risk. Pros and cons for using these risk markers are discussed. RECENT FINDINGS:Both HDL cholesterol and apoA-I are in most clinical co...

journal_title：Current opinion in cardiology

authors： Walldius G,Jungner I

更新日期：2007-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To date 16 genes have been associated with arrhythmogenic cardiomyopathy (ACM). Mutations in these genes can lead to a broad spectrum of phenotypic expression ranging from disease affecting predominantly the right or left ventricle, to biventricular subtypes. Understanding the genetic causes of ACM is...

journal_title：Current opinion in cardiology

authors： Karmouch J,Protonotarios A,Syrris P

更新日期：2018-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Pulmonary hypertension is a progressive disease of the pulmonary vasculature characterized by increased vascular resistance and pressure overload of the right ventricle. This review aims to describe the diagnostic and prognostic role of echocardiography in pulmonary hypertension with particular consid...

journal_title：Current opinion in cardiology

authors： Bossone E,Ferrara F,Grünig E

更新日期：2015-11-01 00:00:00

abstract：PURPOSE OF REVIEW:For over a decade, vulnerabilities in the healthcare industry have been identified. Medical devices such as cardiovascular implantable electronic devices (CIEDs) are particularly concerning because of direct threats to patient safety and protected health information (PHI). Although these vulnerabiliti...

journal_title：Current opinion in cardiology

authors： Tomaiko E,Zawaneh MS

更新日期：2021-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Although arterial hypertension is less common in children than in adults, there is growing concern about elevated blood pressure (BP) in children and adolescents not only because of the association of elevated values with the overweight epidemic, but also as cardiovascular functions are determined in ...

journal_title：Current opinion in cardiology

authors： Santi M,Simonetti BG,Leoni-Foglia CF,Bianchetti MG,Simonetti GD

更新日期：2015-07-01 00:00:00

abstract：:Hypertrophic cardiomyopathy has been shown to be a genetically heterogeneous disorder, linked to at least four different loci on chromosomes 14, 1, 15, and 11. Thus far, three genes have been identified that harbor mutations leading to hypertrophic cardiomyopathy. These genes--cardiac beta myosin heavy chain, alpha tr...

journal_title：Current opinion in cardiology

authors： Elstein E

更新日期：1995-05-01 00:00:00

abstract：PURPOSE OF REVIEW:In this review, we firstly highlight the role of dyslipidemia as a trigger in the initiation and progression of endothelial dysfunction, considered the earliest atherosclerotic lesion and patent in children with risk factors.In this context, we also revise methods that reflect the impact of endothelia...

journal_title：Current opinion in cardiology

authors： Pires A,Sena C,Seiça R

更新日期：2016-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Penetrating aortic ulcer (PAU) is defined as ulceration of an aortic atherosclerotic plaque penetrating through the internal elastic lamina into the media. With the advances in imaging techniques, the differential diagnosis between PAU and other aortic ulcers remains a challenge. This review aims to s...

journal_title：Current opinion in cardiology

authors： Evangelista A,Moral S

更新日期：2020-11-01 00:00:00

abstract：PURPOSE OF REVIEW:High-density lipoprotein cholesterol (HDL-C) has been well established as an inverse predictor of coronary heart disease (CHD), and in recent years, investigations have focused on the genetic regulation of high-density lipoprotein. Although numerous candidate genes contribute to the low HDL-C phenotyp...

journal_title：Current opinion in cardiology

authors： Miller M,Zhan M

更新日期：2004-07-01 00:00:00