Strategies to minimize bleeding complications of percutaneous coronary intervention.

Abstract:

PURPOSE OF REVIEW:Bleeding has recently been identified as a major adverse outcome in patients with acute coronary syndromes. In this review, the importance of the association of bleeding with mortality and strategies to reduce bleeding with percutaneous coronary intervention are discussed. RECENT FINDINGS:Nine trials have shown an association of bleeding with mortality. The influence of major bleeding is at least equivalent to the effect of a myocardial infarction. In order to reduce bleeding, individualized risk assessment should be performed and attention paid to choice of access, antithrombotic, dose of antithrombotic, avoidance of crossing over from one antithrombotic to another, smaller sheaths and early removal as well as choice of P2Y12 inhibitor. SUMMARY:Individualizing treatment and strategies to reduce both ischemic events and bleeding will improve patient outcomes.

journal_name

Curr Opin Cardiol

authors

White HD

doi

10.1097/HCO.0b013e32832d1ea2

subject

Has Abstract

pub_date

2009-07-01 00:00:00

pages

273-8

issue

4

eissn

0268-4705

issn

1531-7080

journal_volume

24

pub_type

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