The role of antiplatelet therapy in the secondary prevention of coronary artery disease.

abstract：:Recent epidemiologic studies of the risk factors for early and late phases of transplant coronary artery disease (TxCAD) have identified metabolic abnormalities such as hyperlipidemia and insulin resistance as important risk factors, independent of rejection. In randomized trials, calcium channel blockers and hydroxym...

journal_title：Current opinion in cardiology

authors： Valantine-von Kaeppler HA

更新日期：1998-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Pulmonary hypertension is a progressive disease of the pulmonary vasculature characterized by increased vascular resistance and pressure overload of the right ventricle. This review aims to describe the diagnostic and prognostic role of echocardiography in pulmonary hypertension with particular consid...

journal_title：Current opinion in cardiology

authors： Bossone E,Ferrara F,Grünig E

更新日期：2015-11-01 00:00:00

abstract：PURPOSE OF REVIEW:As the number of people living with heart failure continues to grow, future treatments will focus on efficient donor organ donation and ensuring safe and durable outcomes. This review will focus on organ procurement, graft surveillance and emerging therapies. RECENT FINDINGS:Preliminary studies into ...

journal_title：Current opinion in cardiology

authors： Hasan R,Ela AAE,Goldstein D

更新日期：2017-05-01 00:00:00

abstract：:Primary cardiac tumors are rare clinical entities. Benign tumors are often amenable to surgical excision, whereas malignant tumors are seldom resectable. The literature has reported that 28 patients have undergone orthotopic heart transplantation for inoperable primary cardiac tumors. The results of these transplants ...

journal_title：Current opinion in cardiology

authors： Gowdamarajan A,Michler RE

更新日期：2000-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The severity of low-flow, low-gradient aortic stenosis cases continue to be misunderstood because of challenging diagnosis, and treatment remains complex. We discuss current diagnostic and treatment modalities for low-flow, low-gradient aortic stenosis. RECENT FINDINGS:This article summarizes current...

journal_title：Current opinion in cardiology

authors： Salemi A,Hameed I,Khan FM,Gaudino M

更新日期：2020-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The possible role of several neurohormonal factors in pathogenesis of hypertension has been studied extensively both in humans and in experimental animal models. However, controversial data from some previous studies are indecisive and call for reassessment and development of new targets. This mini-re...

journal_title：Current opinion in cardiology

authors： Wang DH

更新日期：2008-07-01 00:00:00

abstract：:Coronary artery bypass surgery performed in patients with coronary artery disease and left ventricular dysfunction improves survival compared with antianginal therapy alone. The mechanisms for this survival advantage with revascularization therapy have not been systematically elucidated. Many of these patients have "h...

journal_title：Current opinion in cardiology

authors： DeNofrio D,Loh E

更新日期：1996-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Cardiovascular disease (CVD) is the leading cause of morbidity and premature mortality in Europe and the United States, and is increasingly common in developing countries. High-density lipoprotein cholesterol (HDL-C) is an independent risk factor for CVD and is superior to low-density lipoprotein chol...

journal_title：Current opinion in cardiology

authors： Schofield JD,France M,Ammori B,Liu Y,Soran H

更新日期：2013-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Myocardial fibrosis is a common feature of many cardiomyopathies, including hypertrophic cardiomyopathy. Myocardial fibrosis has been shown to be reversible and treatable with timely intervention. Although early detection and assessment of fibrosis is crucial, adequate diagnostics are still in develop...

journal_title：Current opinion in cardiology

authors： Won S,Davies-Venn C,Liu S,Bluemke DA

更新日期：2013-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Statins are widely utilized for low-density lipoprotein lowering and for prevention of atherosclerotic cardiovascular disease. Although these drugs have a good safety record, increased risk of developing diabetes during extended use has recently garnered attention. Here we review clinical trial eviden...

journal_title：Current opinion in cardiology

authors： Sampson UK,Linton MF,Fazio S

更新日期：2011-07-01 00:00:00

abstract：:In addition to necrosis, apoptosis makes a significant contribution to cell death following acute myocardial ischemia; apoptosis is particularly enhanced during reperfusion. Several studies are beginning to indicate that the cell death by apoptosis may be preventable. A boost in the research in this direction has been...

journal_title：Current opinion in cardiology

authors： Garg S,Hofstra L,Reutelingsperger C,Narula J

更新日期：2003-09-01 00:00:00

abstract：PURPOSE OF REVIEW:C-reactive protein, a nonspecific marker of inflammation, has recently been proposed both as a marker of low-grade inflammation involved in atherogenesis and as a predictor of disease progression. RECENT FINDINGS:The physiologic functions of C-reactive protein as an anti-inflammatory scavenger molecu...

journal_title：Current opinion in cardiology

authors： Sepulveda JL,Mehta JL

更新日期：2005-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This review examines the application of next-generation sequencing (NGS) technologies in the identification of the causation of nonsyndromic genetic cardiomyopathies. RECENT FINDINGS:NGS sequencing of the entire genetic coding sequence (the exome) has successfully identified five novel genes and caus...

journal_title：Current opinion in cardiology

authors： Norton N,Li D,Hershberger RE

更新日期：2012-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Body habitus is a key lifestyle characteristic whose current status and future projections are disconcerting. The percentage of the global population who are either overweight or obese has substantially increased, with no indication that any country has a solution to this issue. Hypertension is a key ...

journal_title：Current opinion in cardiology

authors： Arena R,Daugherty J,Bond S,Lavie CJ,Phillips S,Borghi-Silva A

更新日期：2016-07-01 00:00:00

abstract：:The ECG is the most widely used noninvasive diagnostic and prognostic test administered to patients with suspected or proven coronary artery disease. When considering appropriate use of the electrocardiogram, physicians need to examine the clinical question being asked, the additional information that can be derived,...

journal_title：Current opinion in cardiology

authors： Al-Joundi B,Chaitman BR

更新日期：1992-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide a broad overview of the current state of knowledge of coronary artery bypass grafting with bilateral internal thoracic artery (BITA). RECENT FINDINGS:There exists a large body of literature from mostly observational studies supporting the use of BITA in patients undergoing coronary artery ...

journal_title：Current opinion in cardiology

authors： Yanagawa B,Verma S,Puskas JD

更新日期：2017-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The efficacy of anticoagulation for valvular prostheses is the result of a delicate balance between the risk of thromboembolic (TE) events and bleeding. Here, we review data on anticoagulation for valve prostheses with a focus on clinical trials that address key unanswered questions. RECENT FINDINGS:...

journal_title：Current opinion in cardiology

authors： Yanagawa B,Whitlock RP,Verma S,Gersh BJ

更新日期：2016-03-01 00:00:00

abstract：:Optimized medical treatment for the non-ST segment elevation acute coronary syndromes (NSTE ACS) should consist of a combined antithrombotic/anti-anginal regimen. Standard antithrombotic treatment is currently unfractionated heparin and aspirin, and in high-risk patients glycoprotein IIb/IIIa inhibitors. However, low-...

journal_title：Current opinion in cardiology

authors： Cohen M

更新日期：2001-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The appropriate treatment of patients with acute pulmonary embolism who present with right ventricular dysfunction but normal arterial blood pressure, and particularly the potential benefits of thrombolytic treatment in this setting, continue to be highly controversial. In the past year, several well ...

journal_title：Current opinion in cardiology

authors： Konstantinides S

更新日期：2005-11-01 00:00:00

abstract：:There has been an intensive effort in the past year to identify immunologic and nonimmunologic factors in the pathogenesis of cardiac allograft vasculopathy. Significant progress has been made regarding cell proliferation and cell death, with particular focus on cell growth factors, cell death factors, and their recep...

journal_title：Current opinion in cardiology

authors： Dong C,Redenbach D,Wood S,Battistini B,Wilson JE,McManus BM

更新日期：1996-03-01 00:00:00

abstract：:Intravenous thrombolysis has become a primary mode of reperfusion therapy for selected patients with acute myocardial infarction. The timing and potential benefits of cardiac angiography and coronary revascularization after thrombolysis in patients experiencing an uncomplicated myocardial infarction have been extensiv...

journal_title：Current opinion in cardiology

authors： Aguirre FV,Merritt RF,Carollo SC

更新日期：1995-07-01 00:00:00

abstract：:Fewer than 50 pediatric lung transplants are performed each year. Surgical advances in the field have resulted in improved operative outcomes and in technical innovations that have broadened both the target population and the donor pool. At the same time, late referral of critically ill patients and shortage of donor ...

journal_title：Current opinion in cardiology

authors： Bridges ND

更新日期：1998-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Coarctation of the aorta is the discrete narrowing of the proximal descending aorta and is the sixth most common lesion in congenital heart disease. Repair of the coarctation can relieve the obstruction, but recurrent coarctation and future aneurysm formation can occur, and a heightened risk of vascul...

journal_title：Current opinion in cardiology

authors： Tanous D,Benson LN,Horlick EM

更新日期：2009-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Open aortic arch surgery is highly invasive and may result in significant morbidity. Recent innovations in thoracic stent-graft technology have facilitated methods of replacing the aortic arch without deep hypothermic circulatory arrest or even cardiopulmonary bypass. We present a review of the curren...

journal_title：Current opinion in cardiology

authors： Desai ND,Szeto WY

更新日期：2009-11-01 00:00:00

abstract：:The increased use of arterial conduits in coronary artery bypass grafting is reflected in numerous publications addressing indications, choice of conduits, and possible side-effects. Besides the internal thoracic artery, the right gastroepiploic artery is becoming established, and the inferior epigastric artery is be...

journal_title：Current opinion in cardiology

authors： Turina M

更新日期：1993-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To compare the potential of high-density lipoprotein (HDL) cholesterol and apolipoprotein (apo) A-I, the major protein in HDL particles, in predicting cardiovascular risk. Pros and cons for using these risk markers are discussed. RECENT FINDINGS:Both HDL cholesterol and apoA-I are in most clinical co...

journal_title：Current opinion in cardiology

authors： Walldius G,Jungner I

更新日期：2007-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The natural history of cardiogenic shock has improved significantly with the utilization of revascularization and mechanical circulatory support. Despite the interest in identifying new pharmacological agents, the medical therapy to restore perfusion is limited by their side-effects and no solid evide...

journal_title：Current opinion in cardiology

authors： Nativi-Nicolau J,Selzman CH,Fang JC,Stehlik J

更新日期：2014-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitors are promising therapies that inhibit the degradation of low-density lipoprotein (LDL) receptors in the hepatocyte and thus increase LDL cholesterol (LDL-C) uptake from the blood. This review summarizes main findings in the field of PCSK9...

journal_title：Current opinion in cardiology

authors： Eisen A,Giugliano RP

更新日期：2016-11-01 00:00:00

abstract：PURPOSE OF REVIEW:This review describes changes in indications for implantable cardioverter-defibrillator (ICD) implantation made in the American College of Cardiology, American Heart Association, and North American Society of Pacing and Electrophysiology 2002 update of the 1998 guideline for the implantation of cardia...

journal_title：Current opinion in cardiology

authors： Epstein AE

更新日期：2004-01-01 00:00:00

abstract：PURPOSE OF REVIEW:This review discusses the role of statin therapy in patients with acute coronary syndromes. These drugs modulate endothelial function and stabilize atherosclerotic plaque by inhibiting oxidative stress and inflammation and may provide a relevant clinical benefit in unstable patients. RECENT FINDINGS:...

journal_title：Current opinion in cardiology

authors： Nusca A,Melfi R,Patti G,Di Sciascio G

更新日期：2010-07-01 00:00:00