Lung transplantation in children.

Abstract:

:Fewer than 50 pediatric lung transplants are performed each year. Surgical advances in the field have resulted in improved operative outcomes and in technical innovations that have broadened both the target population and the donor pool. At the same time, late referral of critically ill patients and shortage of donor organs result in death prior to transplantation for many children, and substantial biological barriers exist that prevent achievement of satisfactory long-term outcomes for the many who do undergo a successful surgical procedure. Until we can better understand and overcome these barriers, lung transplantation must be considered a palliative rather than curative procedure. In this article, a brief overview of pediatric lung transplantation is offered, and contributions to the recent literature are summarized.

journal_name

Curr Opin Cardiol

authors

Bridges ND

doi

10.1097/00001573-199801000-00012

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

73-7

issue

1

eissn

0268-4705

issn

1531-7080

journal_volume

13

pub_type

杂志文章,评审
  • Noninvasive imaging of myocardial extracellular matrix for assessment of fibrosis.

    abstract:PURPOSE OF REVIEW:Myocardial fibrosis is a common feature of many cardiomyopathies, including hypertrophic cardiomyopathy. Myocardial fibrosis has been shown to be reversible and treatable with timely intervention. Although early detection and assessment of fibrosis is crucial, adequate diagnostics are still in develop...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0b013e32835f5a2b

    authors: Won S,Davies-Venn C,Liu S,Bluemke DA

    更新日期:2013-05-01 00:00:00

  • Recent advances in non-interventional pediatric cardiac catheterization.

    abstract:PURPOSE OF REVIEW:The role of cardiac catheterization in pediatric cardiology has changed significantly in the past 10-15 years. As interventional procedures dominate the field, it is important to examine the recent advances in non-interventional pediatric cardiac catheterization. RECENT FINDINGS:Meaningful and accura...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/01.hco.0000154067.99851.4a

    authors: Kanter JP,Hellenbrand WE

    更新日期:2005-03-01 00:00:00

  • An update on implantable cardioverter-defibrillator guidelines.

    abstract:PURPOSE OF REVIEW:This review describes changes in indications for implantable cardioverter-defibrillator (ICD) implantation made in the American College of Cardiology, American Heart Association, and North American Society of Pacing and Electrophysiology 2002 update of the 1998 guideline for the implantation of cardia...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-200401000-00006

    authors: Epstein AE

    更新日期:2004-01-01 00:00:00

  • Anticoagulation for prosthetic heart valves: unresolved questions requiring answers.

    abstract:PURPOSE OF REVIEW:The efficacy of anticoagulation for valvular prostheses is the result of a delicate balance between the risk of thromboembolic (TE) events and bleeding. Here, we review data on anticoagulation for valve prostheses with a focus on clinical trials that address key unanswered questions. RECENT FINDINGS:...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0000000000000259

    authors: Yanagawa B,Whitlock RP,Verma S,Gersh BJ

    更新日期:2016-03-01 00:00:00

  • Ion channels and ventricular arrhythmias: cellular and ionic mechanisms underlying the Brugada syndrome.

    abstract::Brugada syndrome is characterized by ST segment elevation in the right precordial leads, V1-V3 (unrelated to ischemia or structural disease), normal QT intervals, apparent right bundle branch block, and sudden cardiac death, particularly in men of Asian origin. An autosomal dominant mode of inheritance with variable e...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-199905000-00013

    authors: Antzelevitch C

    更新日期:1999-05-01 00:00:00

  • Genetics of coronary artery disease: should they impact the choice of revascularization?

    abstract:PURPOSE OF REVIEW:Patients with multivessel coronary artery disease (CAD) may undergo revascularization by either percutaneous coronary intervention (PCI) or coronary artery bypass graft surgery (CABG). This review will discuss the use of polygenic risk scores for risk-stratification of patients with multivessel CAD in...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0000000000000560

    authors: Hui SK,Lindale E,Sun L,Ruel M

    更新日期:2018-11-01 00:00:00

  • New strategies in myocardial preservation.

    abstract::Myocardial protection seems to be evolving toward simplified techniques, among which the use of minimally diluted tepid blood cardioplegia delivered retrograde or in a combined fashion is gaining wider clinical acceptance. In the future, agents that can duplicate the cardioprotective effects of ischemic preconditionin...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-199711000-00002

    authors: Menasché P

    更新日期:1997-11-01 00:00:00

  • Vagal stimulation for heart failure.

    abstract:PURPOSE OF REVIEW:On the very solid background of experimental and clinical studies pointing to the cardiovascular risks associated with depressed vagal reflexes and supported by specific experiments in animal models of heart failure, we are witnessing a rapidly growing interest in the very untraditional approach to th...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0b013e3283413961

    authors: Schwartz PJ

    更新日期:2011-01-01 00:00:00

  • Evolving concepts on benefits and risks associated with therapeutic strategies to raise HDL.

    abstract:PURPOSE OF REVIEW:To provide an update on high-density lipoprotein (HDL) biology and emerging new HDL-based therapies for athero-thrombosis. RECENT FINDINGS:Atherosclerotic cardiovascular disease remains a major public health threat despite a significant decline over the past three decades. Although current medical th...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0b013e32833f0382

    authors: Shah PK

    更新日期:2010-11-01 00:00:00

  • Biventricular pacing in congestive heart failure: a boost toward finer living.

    abstract::With 550,000 new cases each year, congestive heart failure is a major medical problem. Several medical therapies, including digoxin, angiotensin-converting enzyme inhibitors, and beta-blockers, have reduced the number of re-hospitalizations and slowed the progression of congestive heart failure. Angiotensin-converting...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-200201000-00014

    authors: Luck JC,Wolbrette DL,Boehmer JP,Ulsh PJ,Silber D,Naccarelli GV

    更新日期:2002-01-01 00:00:00

  • The molecular genetics of congenital heart disease: a review of recent developments.

    abstract:PURPOSE OF REVIEW:Our understanding of the interactions of genes and pathways during heart development continues to expand with our knowledge of the genetic basis of congenital heart disease. Along with the discovery of specific genes that cause lesions, recent research has focused on the interactions of some previousl...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0b013e328337b4ce

    authors: Wolf M,Basson CT

    更新日期:2010-05-01 00:00:00

  • Cardiac angiogenesis and gene therapy: a strategy for myocardial revascularization.

    abstract::Angiogenesis, the de novo formation of new vasculature, is a critical response to ischemia that provides neovascularization of ischemic tissues. In therapeutic angiogenesis, an angiogen--a mediator that induces angiogenesis--is delivered to targeted tissues, augmenting the native angiogenic process and enhancing reper...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-199911000-00012

    authors: Hamawy AH,Lee LY,Crystal RG,Rosengart TK

    更新日期:1999-11-01 00:00:00

  • Will left-ventricular assist device therapy replace heart transplantation in the foreseeable future?

    abstract:PURPOSE OF REVIEW:Implantation of circulatory assist devices as a permanent alternative to heart transplantation, so-called Destination Therapy, has become a promising new option for treatment of patients with advanced heart failure who are not candidates for heart transplantation. RECENT FINDINGS:The landmark REMATCH...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/01.hco.0000153949.42189.03

    authors: Lietz K,Miller LW

    更新日期:2005-03-01 00:00:00

  • Ultrafiltration for congestive heart failure: the past and the present.

    abstract:PURPOSE OF REVIEW:To provide an overview on the most recent evidence for the use of extracorporeal and peritoneal ultrafiltration in heart failure, focusing on the major publications from the last few years. RECENT FINDINGS:There have been several studies investigating the possible use of extracorporeal and peritoneal...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章

    doi:10.1097/HCO.0000000000000139

    authors: Marenzi G,Kazory A,Agostoni P

    更新日期:2015-03-01 00:00:00

  • A new myocardial conversion of angiotensin I.

    abstract::The therapeutic benefits of angiotensin-converting enzyme inhibitors in the treatment of hypertension, congestive heart failure, and atherosclerotic heart disease are undeniable. Recent studies, however, suggest that the cardioprotective effect produced by these drugs is complex and may not be solely related to inhibi...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-199409000-00004

    authors: Ferrario CM,Chappell MC

    更新日期:1994-09-01 00:00:00

  • Transmyocardial laser revascularization for inoperable coronary artery disease.

    abstract::Interest in transmyocardial laser revascularization for the treatment of otherwise inoperable coronary artery disease has increased rather dramatically in recent years. The results of several industrially sponsored clinical series have been reported recently, all with significant improvement in angina pectoris that ap...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:

    authors: Sundt TM 3rd,Rogers JG

    更新日期:1997-09-01 00:00:00

  • Carotid artery stenting: a 2009 update.

    abstract:PURPOSE OF REVIEW:Carotid endarterectomy (CEA) is still considered the gold standard in the treatment of patients with significant carotid stenosis and has proven its value over the past decades. Endovascular techniques have evolved, and carotid artery stenting (CAS) is challenging CEA to become the better treatment. V...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0b013e328330c302

    authors: Zeebregts CJ,Meerwaldt R,Geelkerken RH

    更新日期:2009-11-01 00:00:00

  • Management of patients with end-stage renal disease: coronary artery bypass graft surgery versus percutaneous coronary intervention.

    abstract:PURPOSE OF REVIEW:Coronary artery disease is common in patients with end-stage renal disease (ESRD) on hemodialysis. ESRD patients are prone to atherosclerosis and are likely to present with advanced CAD requiring coronary artery bypass graft surgery (CABG) or percutaneous coronary intervention (PCI). RECENT FINDINGS:...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0000000000000539

    authors: Karkhanis R,Tam DY,Fremes SE

    更新日期:2018-09-01 00:00:00

  • Five decades of pediatric heart transplantation: challenges overcome, challenges remaining.

    abstract:PURPOSE OF REVIEW:Pediatric heart transplants continue to be the therapy of choice for children with end stage heart failure. The interplay of limited donor supply, improvement in ventricular assist device (VAD) technology and utilization, and a focus on optimizing long-term outcomes make it critically important for pr...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0000000000000351

    authors: Zangwill S

    更新日期:2017-01-01 00:00:00

  • Emerging clinical roles for ambulatory blood pressure monitoring.

    abstract::Ambulatory blood pressure monitoring is becoming increasingly popular in the diagnosis and treatment of patients with hypertensive disorders. Widespread clinical use, however, has been limited by a lack of normative data and prospective, controlled clinical studies of its impact on subsequent cardiovascular morbidity ...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-199309000-00007

    authors: Canzanello VJ,Sheps SG

    更新日期:1993-09-01 00:00:00

  • Diagnosis and management of low-flow, low-gradient aortic stenosis.

    abstract:PURPOSE OF REVIEW:The severity of low-flow, low-gradient aortic stenosis cases continue to be misunderstood because of challenging diagnosis, and treatment remains complex. We discuss current diagnostic and treatment modalities for low-flow, low-gradient aortic stenosis. RECENT FINDINGS:This article summarizes current...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章

    doi:10.1097/HCO.0000000000000707

    authors: Salemi A,Hameed I,Khan FM,Gaudino M

    更新日期:2020-03-01 00:00:00

  • Type A aortic dissection complicated by malperfusion syndrome.

    abstract:PURPOSE OF REVIEW:Malperfusion is present in up to 40% of acute type A aortic dissections (ATAADs) and results in increased morbidity and mortality. This review presents different management strategies in patients with ATAAD and malperfusion to improve outcomes. RECENT FINDINGS:While the ideal management strategy of A...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0000000000000667

    authors: Norton EL,Khaja MS,Williams DM,Yang B

    更新日期:2019-11-01 00:00:00

  • Multifocal arterial disease: clinical implications and management.

    abstract:PURPOSE OF REVIEW:Vascular disease often affects more than one territory. Atherosclerosis is a global disease affecting multiple organs/systems. Cardiovascular risk factors are associated with an increased risk for the development of arterial disease in all vascular beds but differ in their individual impacts for each ...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章

    doi:10.1097/HCO.0000000000000746

    authors: Paraskevas KI,Geroulakos G,Veith FJ,Mikhailidis DP

    更新日期:2020-07-01 00:00:00

  • Preventive cardiology in the elderly.

    abstract::Cardiovascular disease is the leading cause of death world-wide in populations older than 65 years of age. The variation in cardiovascular mortality rates in this population indicates a substantial potential for effective coronary prevention. The highest risk for development of coronary heart disease is in individuals...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-199703000-00017

    authors: Wenger NK

    更新日期:1997-03-01 00:00:00

  • Benefits and limitations of database analysis for outcome prediction in cardiac surgery.

    abstract::Large databases are being used for outcome prediction analysis with increasing frequency. This review examines four separate databases used to provide risk analysis in the cardiac surgery population. Populations in the databases range in size from 3500 to over 116,000 patients. All of the databases were applied on ...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-199204000-00014

    authors: Park SE,Cmolik BL,Clark RE

    更新日期:1992-04-01 00:00:00

  • New insights on renovascular hypertension.

    abstract::Although activation of the endocrine renin-angiotensin system with consequent vasoconstriction and salt retention have long been known as the hallmarks of the early phase of renovascular hypertension, the recent recognition of a local vascular angiotensin system and the understanding of the process of vascular remodel...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-199409000-00015

    authors: Ma AO,Gibbons GH

    更新日期:1994-09-01 00:00:00

  • Management of aortic dissection.

    abstract::Patients with aortic dissection are divided into two main groups: those with hypertension and those with syndromes involving hereditary defects of the aortic wall. The common finding in the setting of both Marfan syndrome and hypertension is dilatation of the aorta. The biological events that may lead to dissection ar...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:

    authors: Westaby S

    更新日期:1995-09-01 00:00:00

  • Statin loading for acute coronary syndromes.

    abstract:PURPOSE OF REVIEW:This review discusses the role of statin therapy in patients with acute coronary syndromes. These drugs modulate endothelial function and stabilize atherosclerotic plaque by inhibiting oxidative stress and inflammation and may provide a relevant clinical benefit in unstable patients. RECENT FINDINGS:...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0b013e32833987ca

    authors: Nusca A,Melfi R,Patti G,Di Sciascio G

    更新日期:2010-07-01 00:00:00

  • Update on digoxin and other oral positive inotropic agents for chronic heart failure.

    abstract::The benefit of digoxin in chronic heart failure has been debated fervently for decades. In the 1970s, the use of digoxin was challenged due to the high incidences of digitalis toxicity and the lack of data on the effects of digoxin in patients with chronic heart failure. In the 1980s, interest in digoxin was renewed a...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-199705000-00004

    authors: Reddy S,Benatar D,Gheorghiade M

    更新日期:1997-05-01 00:00:00

  • Does carotid intima media thickness indicate coronary atherosclerosis?

    abstract::Increased carotid intima media thickness (IMT) is relatively simple, inexpensive, and reproducible noninvasive marker of global atherosclerotic disease. It is a frequently used experimental tool in epidemiologic studies to identify and follow cardiovascular disease. There is evidence that early detection of atheroscle...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-200209000-00013

    authors: Sinha AK,Eigenbrodt M,Mehta JL

    更新日期:2002-09-01 00:00:00