Apoptosis as a therapeutic target in acutely ischemic myocardium.

abstract：PURPOSE OF REVIEW:To provide an overview of recent clinical trial findings relevant to cardiovascular risk management in patients with diabetes. RECENT FINDINGS:Recent trial evidence has demonstrated benefits of routine blood pressure (BP) lowering, regardless of initial BP levels, in people with type 2 diabetes. In a...

journal_title：Current opinion in cardiology

authors： Patel A,Joshi R,de Galan B

更新日期：2009-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Maximalist low-density lipoprotein (LDL)-lowering strategies such as lowering LDL as much as possible or, alternatively, using the most potent LDL-lowering regimens have become increasingly popular. Almost all attention has focused on the potential advantages of these approaches with little focus on t...

journal_title：Current opinion in cardiology

authors： Sniderman AD,De Graaf J,Couture P

更新日期：2012-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiomyopathy, diagnosed by left ventricular hypertrophy of at least 15 mm maximal wall thickness (MWT). Recent studies reported a sex difference in clinical presentation, progression and outcome of HCM. This review provides an overview of ...

journal_title：Current opinion in cardiology

authors： van Driel B,Nijenkamp L,Huurman R,Michels M,van der Velden J

更新日期：2019-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The severity of low-flow, low-gradient aortic stenosis cases continue to be misunderstood because of challenging diagnosis, and treatment remains complex. We discuss current diagnostic and treatment modalities for low-flow, low-gradient aortic stenosis. RECENT FINDINGS:This article summarizes current...

journal_title：Current opinion in cardiology

authors： Salemi A,Hameed I,Khan FM,Gaudino M

更新日期：2020-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Guidelines indicate surgical intervention for patients with symptomatic severe mitral regurgitation or signs of left ventricular dilatation or dysfunction. However, many patients do not receive surgery because of age or comorbidities, and have poor outcomes with conservative therapy. Transcatheter mit...

journal_title：Current opinion in cardiology

authors： Fam NP,Ross HJ,Verma S

更新日期：2016-03-01 00:00:00

abstract：:The publications of 2000 and 2001 stress how interventional pediatric cardiology has moved from angioplasty to device placement. This review summarizes the important articles during the past year that evaluated the safety and efficacy of atrial septal defect devices, patent ductus occluders, and stents to treat coarct...

journal_title：Current opinion in cardiology

authors： Rocchini AP

更新日期：2002-05-01 00:00:00

abstract：:Coronary artery bypass surgery performed in patients with coronary artery disease and left ventricular dysfunction improves survival compared with antianginal therapy alone. The mechanisms for this survival advantage with revascularization therapy have not been systematically elucidated. Many of these patients have "h...

journal_title：Current opinion in cardiology

authors： DeNofrio D,Loh E

更新日期：1996-07-01 00:00:00

abstract：:This review describes to date the experience with combined heart-kidney transplant (HNTx) from a single donor. HNTxs are very uncommon relative to single-organ transplants of the heart and kidney, as well as combined kidney-pancreas and combined kidney-liver transplants. Two groups of patients seem to be candidates fo...

journal_title：Current opinion in cardiology

authors： Castillo-Lugo JA,Brinker KR

更新日期：1999-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Vitamin D deficiency is common throughout the world, with a particularly high prevalence in northern latitudes and colder climates. Although the best known sequelae of vitamin D deficiency involve the musculoskeletal system, a growing body of evidence suggests that vitamin D status may influence cardi...

journal_title：Current opinion in cardiology

authors： Swales HH,Wang TJ

更新日期：2010-09-01 00:00:00

abstract：:Although activation of the endocrine renin-angiotensin system with consequent vasoconstriction and salt retention have long been known as the hallmarks of the early phase of renovascular hypertension, the recent recognition of a local vascular angiotensin system and the understanding of the process of vascular remodel...

journal_title：Current opinion in cardiology

authors： Ma AO,Gibbons GH

更新日期：1994-09-01 00:00:00

abstract：:Intravenous thrombolysis has become a primary mode of reperfusion therapy for selected patients with acute myocardial infarction. The timing and potential benefits of cardiac angiography and coronary revascularization after thrombolysis in patients experiencing an uncomplicated myocardial infarction have been extensiv...

journal_title：Current opinion in cardiology

authors： Aguirre FV,Merritt RF,Carollo SC

更新日期：1995-07-01 00:00:00

abstract：:Stress myocardial perfusion imaging has become a mainstay in the noninvasive assessment of patients with known or suspected coronary artery disease for several compelling reasons. Radionuclide myocardial perfusion imaging can be performed using a variety of stressors, including exercise, pharmacologic stress (includin...

journal_title：Current opinion in cardiology

authors： Mansoor MR,Heller GV

更新日期：1997-11-01 00:00:00

abstract：:Assessment of the pulmonary circulation and right ventricular function is a cornerstone in the evaluation of the patient as a potential heart transplant recipient. The importance of pulmonary hypertension is linked to outcomes in the posttransplant period. Preoperative pulmonary vascular resistance is an independent r...

journal_title：Current opinion in cardiology

authors： Natale ME,Piña IL

更新日期：2003-03-01 00:00:00

abstract：:Patients with aortic dissection are divided into two main groups: those with hypertension and those with syndromes involving hereditary defects of the aortic wall. The common finding in the setting of both Marfan syndrome and hypertension is dilatation of the aorta. The biological events that may lead to dissection ar...

journal_title：Current opinion in cardiology

authors： Westaby S

更新日期：1995-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Cardiovascular implantable electronic devices are widely used to treat symptomatic arrhythmias, prevent sudden cardiac death, and improve symptoms and cardiac function. Continued population growth and expanding indications have resulted in a progressive increase in the number of cardiovascular implant...

journal_title：Current opinion in cardiology

authors： Sadek MM,Goldstein W,Epstein AE,Schaller RD

更新日期：2016-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Cardiovascular disease (CVD) is the leading cause of morbidity and premature mortality in Europe and the United States, and is increasingly common in developing countries. High-density lipoprotein cholesterol (HDL-C) is an independent risk factor for CVD and is superior to low-density lipoprotein chol...

journal_title：Current opinion in cardiology

authors： Schofield JD,France M,Ammori B,Liu Y,Soran H

更新日期：2013-07-01 00:00:00

abstract：PURPOSE OF REVIEW:While the prognostic power of adenosine single photon emission computed tomography myocardial perfusion imaging has been validated in multiple patient populations including those with known or suspected coronary artery disease, the utility of this modality in assessing risk after an acute myocardial i...

journal_title：Current opinion in cardiology

authors： Dorfman TA,Iskandrian AE

更新日期：2007-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Cardiac magnetic resonance imaging has an expanding role as a preferred modality for the detection and characterization of myocardial viability. RECENT FINDINGS:Improving the accuracy of cardiac magnetic resonance for detecting viable myocardium has been one focus of investigators. In segments with i...

journal_title：Current opinion in cardiology

authors： Isbell DC,Kramer CM

更新日期：2006-09-01 00:00:00

abstract：:With 550,000 new cases each year, congestive heart failure is a major medical problem. Several medical therapies, including digoxin, angiotensin-converting enzyme inhibitors, and beta-blockers, have reduced the number of re-hospitalizations and slowed the progression of congestive heart failure. Angiotensin-converting...

journal_title：Current opinion in cardiology

authors： Luck JC,Wolbrette DL,Boehmer JP,Ulsh PJ,Silber D,Naccarelli GV

更新日期：2002-01-01 00:00:00

abstract：:Large databases are being used for outcome prediction analysis with increasing frequency. This review examines four separate databases used to provide risk analysis in the cardiac surgery population. Populations in the databases range in size from 3500 to over 116,000 patients. All of the databases were applied on ...

journal_title：Current opinion in cardiology

authors： Park SE,Cmolik BL,Clark RE

更新日期：1992-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite progressive improvement in surgical results, hypoplastic left heart syndrome remains one of the congenital heart abnormalities with the greatest morbidity and mortality. Hybrid approaches to management, combining surgical and interventional catheterization procedures, have been introduced to m...

journal_title：Current opinion in cardiology

authors： Gutgesell HP,Lim DS

更新日期：2007-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Non-invasive testing is often the first step in the evaluation of stable coronary artery disease (CAD). Stress cardiac magnetic resonance imaging (CMR) is an established modality with high diagnostic accuracy and prognostic value. This review will focus on the recent advances in understanding how stre...

journal_title：Current opinion in cardiology

authors： Ge Y,Deva DP,Connelly KA,Yan AT

更新日期：2020-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Atrial fibrillation after cardiac surgery is associated with adverse outcomes and increased costs. Accordingly, therapy should be provided to prevent postoperative atrial fibrillation. The evaluation of therapies to do so is an area of active investigation with significant recent advances. The purpose...

journal_title：Current opinion in cardiology

authors： Mitchell LB

更新日期：2007-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Infective endocarditis continues to pose major challenges in diagnosis and management despite advances in understanding the epidemiology, microbiology, and pathology of the disease. The purpose of this article is to provide a review of diagnosis, microbiology, and treatment of infective endocarditis, ...

journal_title：Current opinion in cardiology

authors： Devlin RK,Andrews MM,von Reyn CF

更新日期：2004-03-01 00:00:00

abstract：:Hypertrophic cardiomyopathy is a primary myocardial disorder with an autosomal pattern of inheritance, characterized by asymmetric left ventricular hypertrophy with myocyte and myofibrillar disarray. Approximately 30% to 50% of all cases are accounted for by mutations in the beta-cardiac myosin heavy chain gene on chr...

journal_title：Current opinion in cardiology

authors： Vassalli G,Seiler C,Hess OM

更新日期：1994-05-01 00:00:00

abstract：PURPOSE OF REVIEW:On the very solid background of experimental and clinical studies pointing to the cardiovascular risks associated with depressed vagal reflexes and supported by specific experiments in animal models of heart failure, we are witnessing a rapidly growing interest in the very untraditional approach to th...

journal_title：Current opinion in cardiology

authors： Schwartz PJ

更新日期：2011-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Transseptal endocardial left-ventricular pacing has a number of potential advantages over left-ventricular epicardial pacing from the coronary sinus, for implantation of cardiac resynchronization therapy (CRT) devices. In this study we review the risks and potential benefits. RECENT FINDINGS:Permanen...

journal_title：Current opinion in cardiology

authors： Whinnett Z,Bordachar P

更新日期：2012-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The prevention and treatment of rejection have been the major focus of clinical and research studies since the inception of heart transplantation. Recent improvement in survival after transplant has been in large part due to continued advancement in antirejection therapies. RECENT FINDINGS:The combin...

journal_title：Current opinion in cardiology

authors： Chan M,Pearson GJ

更新日期：2007-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Statins significantly reduce cardiovascular morbidity and mortality in patients with and without coronary heart disease. Recently, much debate has focused on use of statins for primary prevention following a class-wide safety label change by the US Food and Drug Administration amidst concerns of worse...

journal_title：Current opinion in cardiology

authors： Minder CM,Blumenthal RS,Blaha MJ

更新日期：2013-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Hypertension and dyslipidemia frequently coexist, and endothelial dysfunction is associated with the pathophysiology of both atherosclerosis and hypertension. Evidence is convincing for an overlapping role of oxidative stress, renin-angiotensin system activation, and dyslipidemia in the genesis of end...

journal_title：Current opinion in cardiology

authors： Sarkar K,Sinha AK,Mehta JL

更新日期：2006-07-01 00:00:00