Vitamin D and cardiovascular disease risk: emerging evidence.

Abstract:

PURPOSE OF REVIEW:Vitamin D deficiency is common throughout the world, with a particularly high prevalence in northern latitudes and colder climates. Although the best known sequelae of vitamin D deficiency involve the musculoskeletal system, a growing body of evidence suggests that vitamin D status may influence cardiovascular health as well. This review focuses on recent studies linking vitamin D and cardiovascular disease risk, emphasizing the potential relevance to primary prevention. RECENT FINDINGS:There is strong experimental evidence that vitamin D status may influence cardiovascular structure and function. The number of clinical studies has steadily grown in recent years, with the largest number comprising observational studies showing associations between low vitamin D status, the presence of various cardiovascular risk factors, and adverse cardiovascular outcomes. A few small, randomized, controlled studies have been published, but these have been largely inconclusive. SUMMARY:Despite substantial clinical evidence linking vitamin D deficiency with increased cardiovascular risk, it remains to be established whether this represents a causal association. Further study is needed with prospective, randomized controlled trials before vitamin D supplementation can be routinely recommended for the primary or secondary prevention of cardiovascular disease.

journal_name

Curr Opin Cardiol

authors

Swales HH,Wang TJ

doi

10.1097/HCO.0b013e32833cd491

subject

Has Abstract

pub_date

2010-09-01 00:00:00

pages

513-7

issue

5

eissn

0268-4705

issn

1531-7080

journal_volume

25

pub_type

杂志文章,评审
  • Low-density lipoprotein-lowering strategies: target versus maximalist versus population percentile.

    abstract:PURPOSE OF REVIEW:Maximalist low-density lipoprotein (LDL)-lowering strategies such as lowering LDL as much as possible or, alternatively, using the most potent LDL-lowering regimens have become increasingly popular. Almost all attention has focused on the potential advantages of these approaches with little focus on t...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0b013e328353fed5

    authors: Sniderman AD,De Graaf J,Couture P

    更新日期:2012-07-01 00:00:00

  • Minimally invasive pediatric cardiac surgery.

    abstract::Minimally invasive cardiac surgery has evolved in response to the intrinsic irony facing cardiac surgeons: that we must injure our patients to treat them. In recent years, advances in fiberoptic imaging technology, applied to other surgical specialties, suggested the possibility that cardiac surgery might also be perf...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-199901000-00011

    authors: Burke RP

    更新日期:1999-01-01 00:00:00

  • Evolving concepts on benefits and risks associated with therapeutic strategies to raise HDL.

    abstract:PURPOSE OF REVIEW:To provide an update on high-density lipoprotein (HDL) biology and emerging new HDL-based therapies for athero-thrombosis. RECENT FINDINGS:Atherosclerotic cardiovascular disease remains a major public health threat despite a significant decline over the past three decades. Although current medical th...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0b013e32833f0382

    authors: Shah PK

    更新日期:2010-11-01 00:00:00

  • Coronary bypass surgery: from variability to standardization?

    abstract:PURPOSE OF REVIEW:The review summarizes recent literature on standardization of care in coronary artery bypass grafting (CABG), with particular attention to the impact of standardization on outcomes and resource utilization. RECENT FINDINGS:An increasing number of studies have demonstrated potential advantages to stan...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0000000000000113

    authors: Kilic A,Whitman GJ

    更新日期:2014-11-01 00:00:00

  • Update on cardiac catheterization and coronary arteriography.

    abstract::Indications for cardiac catheterization--including coronary angiography--have substantially broadened with the advent of nonsurgical therapeutic interventions performed in the catheterization laboratory. Consequently, the increasing number of facilities performing these procedures require clear and unmistakable guidel...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-199307000-00004

    authors: Rafflenbeul W,Riedel M

    更新日期:1993-07-01 00:00:00

  • Identification of patients with hypertrophic cardiomyopathy at high risk for sudden death.

    abstract::Patients with hypertrophic cardiomyopathy are at increased risk for sudden death. Recent studies have improved our ability to risk-stratify such patients and have elucidated several potential mechanisms of sudden death and syncope. Certain noninvasive tests, such as signal-averaged electrocardiography and measurements...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-199501000-00003

    authors: Chang AC,McAreavey D,Fananapazir L

    更新日期:1995-01-01 00:00:00

  • Penetrating atherosclerotic ulcer.

    abstract:PURPOSE OF REVIEW:Penetrating aortic ulcer (PAU) is defined as ulceration of an aortic atherosclerotic plaque penetrating through the internal elastic lamina into the media. With the advances in imaging techniques, the differential diagnosis between PAU and other aortic ulcers remains a challenge. This review aims to s...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0000000000000782

    authors: Evangelista A,Moral S

    更新日期:2020-11-01 00:00:00

  • Nutraceuticals and coronary heart disease.

    abstract:PURPOSE OF REVIEW:Although many reviews have focused on diet as a determinant of coronary heart disease (CHD), little is known about the use of specific nutrients or food products. The aim of this review was to examine the role of several functional foods, or nutraceuticals, in the prevention or treatment of CHD. RECE...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0b013e32836081a5

    authors: Garcia-Rios A,Delgado-Lista J,Alcala-Diaz JF,Lopez-Miranda J,Perez-Martinez P

    更新日期:2013-07-01 00:00:00

  • Innovations in cardiac transplantation.

    abstract:PURPOSE OF REVIEW:As the number of people living with heart failure continues to grow, future treatments will focus on efficient donor organ donation and ensuring safe and durable outcomes. This review will focus on organ procurement, graft surveillance and emerging therapies. RECENT FINDINGS:Preliminary studies into ...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章

    doi:10.1097/HCO.0000000000000392

    authors: Hasan R,Ela AAE,Goldstein D

    更新日期:2017-05-01 00:00:00

  • Emerging clinical roles for ambulatory blood pressure monitoring.

    abstract::Ambulatory blood pressure monitoring is becoming increasingly popular in the diagnosis and treatment of patients with hypertensive disorders. Widespread clinical use, however, has been limited by a lack of normative data and prospective, controlled clinical studies of its impact on subsequent cardiovascular morbidity ...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-199309000-00007

    authors: Canzanello VJ,Sheps SG

    更新日期:1993-09-01 00:00:00

  • New insights on renovascular hypertension.

    abstract::Although activation of the endocrine renin-angiotensin system with consequent vasoconstriction and salt retention have long been known as the hallmarks of the early phase of renovascular hypertension, the recent recognition of a local vascular angiotensin system and the understanding of the process of vascular remodel...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-199409000-00015

    authors: Ma AO,Gibbons GH

    更新日期:1994-09-01 00:00:00

  • Genetics of coronary artery disease: should they impact the choice of revascularization?

    abstract:PURPOSE OF REVIEW:Patients with multivessel coronary artery disease (CAD) may undergo revascularization by either percutaneous coronary intervention (PCI) or coronary artery bypass graft surgery (CABG). This review will discuss the use of polygenic risk scores for risk-stratification of patients with multivessel CAD in...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0000000000000560

    authors: Hui SK,Lindale E,Sun L,Ruel M

    更新日期:2018-11-01 00:00:00

  • Optimizing the treatment of heart failure.

    abstract::The introduction of new drugs, and a re-evaluation of older drugs, have radically changed the pharmacological management of heart failure. Angiotensin converting enzyme (ACE) inhibitors, digitalis, diuretics and the combination of nitrates and hydralazine are now used. The first Cooperative North Scandinavian Enalapri...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-199407000-00005

    authors: Giles TD

    更新日期:1994-07-01 00:00:00

  • Genetics of ventricular tachycardia.

    abstract::Pathogenesis of familial inherited arrhythmias is being progressively clarified thanks to the insights provided by molecular biology and by functional studies. Transmembrane or intracellular ion channel mutations have been identified in genetically determined forms of polymorphic ventricular tachycardia and sudden dea...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-200205000-00003

    authors: Napolitano C,Priori SG

    更新日期:2002-05-01 00:00:00

  • Vagal stimulation for heart failure.

    abstract:PURPOSE OF REVIEW:On the very solid background of experimental and clinical studies pointing to the cardiovascular risks associated with depressed vagal reflexes and supported by specific experiments in animal models of heart failure, we are witnessing a rapidly growing interest in the very untraditional approach to th...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0b013e3283413961

    authors: Schwartz PJ

    更新日期:2011-01-01 00:00:00

  • Ion channels and ventricular arrhythmias: cellular and ionic mechanisms underlying the Brugada syndrome.

    abstract::Brugada syndrome is characterized by ST segment elevation in the right precordial leads, V1-V3 (unrelated to ischemia or structural disease), normal QT intervals, apparent right bundle branch block, and sudden cardiac death, particularly in men of Asian origin. An autosomal dominant mode of inheritance with variable e...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-199905000-00013

    authors: Antzelevitch C

    更新日期:1999-05-01 00:00:00

  • Trials comparing coronary artery bypass grafting with percutaneous transluminal coronary angioplasty and primary stent implantation in patients with multivessel coronary artery disease.

    abstract::With marked improvements in stent technology as adjunct to balloon angioplasty for multivessel coronary disease, several newer trials are currently in progress reviewing the optimal revascularization strategy. This review provides background from older studies and addresses the current progress and design of these new...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-200011000-00003

    authors: Bakhai A,Stables RH,Prasad S,Sigwart U

    更新日期:2000-11-01 00:00:00

  • The risks and benefits of transseptal endocardial pacing.

    abstract:PURPOSE OF REVIEW:Transseptal endocardial left-ventricular pacing has a number of potential advantages over left-ventricular epicardial pacing from the coronary sinus, for implantation of cardiac resynchronization therapy (CRT) devices. In this study we review the risks and potential benefits. RECENT FINDINGS:Permanen...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0b013e32834dc3d4

    authors: Whinnett Z,Bordachar P

    更新日期:2012-01-01 00:00:00

  • Walking: the first steps in cardiovascular disease prevention.

    abstract:PURPOSE OF REVIEW:Health professionals are presented with the challenge of prescribing physical activity that is likely to be sustained by the sedentary majority. Walking is eminently suited to physical activity prescription for inactive individuals as it is accessible to men and women of all ages and social groups and...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0b013e32833ce972

    authors: Murtagh EM,Murphy MH,Boone-Heinonen J

    更新日期:2010-09-01 00:00:00

  • The role of antiplatelet therapy in patients with peripheral artery disease and lower extremity peripheral artery revascularization.

    abstract:PURPOSE OF REVIEW:Although antiplatelet agents are frequently prescribed to patients with lower extremity peripheral artery disease (PAD), there is an overall lack of consensus among published evidence and guidelines with respect to this practice. RECENT FINDINGS:Antiplatelet agents are prescribed to patients with PAD...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0000000000000208

    authors: Banerjee S,Sarode K,Vinas A,Banerjee A,Mohammad A,Brilakis ES

    更新日期:2015-09-01 00:00:00

  • Global patterns of health care for acute coronary syndromes.

    abstract:PURPOSE OF REVIEW:Despite similar guidelines, remarkable global differences exist in the management of acute coronary syndromes. This review describes recent insights in global patterns of patient baseline characteristics, treatment strategies, medication use, and outcome in acute coronary syndromes. RECENT FINDINGS:R...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/01.hco.0000142063.30214.d2

    authors: Sinnaeve PR,Van de Werf FJ

    更新日期:2004-11-01 00:00:00

  • Management of patients with end-stage renal disease: coronary artery bypass graft surgery versus percutaneous coronary intervention.

    abstract:PURPOSE OF REVIEW:Coronary artery disease is common in patients with end-stage renal disease (ESRD) on hemodialysis. ESRD patients are prone to atherosclerosis and are likely to present with advanced CAD requiring coronary artery bypass graft surgery (CABG) or percutaneous coronary intervention (PCI). RECENT FINDINGS:...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0000000000000539

    authors: Karkhanis R,Tam DY,Fremes SE

    更新日期:2018-09-01 00:00:00

  • Prosthetic valve selection in patients with left-sided endocarditis: bioprosthetic or mechanical valves?

    abstract:PURPOSE OF REVIEW:Studies comparing outcomes in left-sided endocarditis based on the prosthesis selected for implantation are limited and no randomized studies have been performed. The purpose of this review is to summarize the best available studies to determine what prosthesis is most appropriate when valve replaceme...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0000000000000040

    authors: Moon MR

    更新日期:2014-03-01 00:00:00

  • C-reactive protein and cardiovascular disease: a critical appraisal.

    abstract:PURPOSE OF REVIEW:C-reactive protein, a nonspecific marker of inflammation, has recently been proposed both as a marker of low-grade inflammation involved in atherogenesis and as a predictor of disease progression. RECENT FINDINGS:The physiologic functions of C-reactive protein as an anti-inflammatory scavenger molecu...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/01.hco.0000175518.57804.94

    authors: Sepulveda JL,Mehta JL

    更新日期:2005-09-01 00:00:00

  • New advances in antirejection therapy.

    abstract:PURPOSE OF REVIEW:The prevention and treatment of rejection have been the major focus of clinical and research studies since the inception of heart transplantation. Recent improvement in survival after transplant has been in large part due to continued advancement in antirejection therapies. RECENT FINDINGS:The combin...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/HCO.0b013e32802bf772

    authors: Chan M,Pearson GJ

    更新日期:2007-03-01 00:00:00

  • Antithrombotic therapy and venous graft disease.

    abstract::Venous graft disease is a thromboproliferative process and places a serious limitation on the symptom-free survival of patients after coronary artery bypass grafting. The efficacy of antithrombotics, especially during the first year after surgery, is suggested by an understanding of the four described phases of diseas...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-199811000-00012

    authors: Schussheim AE,Fuster V

    更新日期:1998-11-01 00:00:00

  • The role of coronary revascularization in the management of heart failure: identification of candidates and review of results.

    abstract::As a result of the increasing size of waiting lists and lengthening of waiting times for heart transplantation, coronary revascularization has emerged as an important therapeutic option in the management of patients with ischemic cardiomyopathy. A critical challenge is the identification of candidates with regions of ...

    journal_title:Current opinion in cardiology

    pub_type: 临床试验,杂志文章,评审

    doi:10.1097/00001573-199605000-00008

    authors: Blitz A,Laks H

    更新日期:1996-05-01 00:00:00

  • The intrinsic cardiac nervous system and atrial fibrillation.

    abstract:PURPOSE OF REVIEW:Radiofrequency ablation techniques to cure cardiac arrhythmias have focused on destroying myocardial tissue involved in abnormal excitation or conduction. This review will address recent basic and clinical studies which suggest that targeting autonomic nerves and ganglia on the large vessels and the h...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/01.hco.0000198980.40390.e4

    authors: Scherlag BJ,Po S

    更新日期:2006-01-01 00:00:00

  • Heart transplantation indicated only in the most severely ill patient: perspectives from the German heart transplant experience.

    abstract::The COCPIT study, performed in a complete national cohort of adult patients consecutively listed for cardiac transplantation in Germany in 1997, found a beneficial effect only in the group that was at high risk of dying from heart failure without transplantation. If these results can be reproduced in other countries, ...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-200103000-00004

    authors: Deng MC,Smits JM,De Meester J,Hummel M,Schoendube F,Scheld HH

    更新日期:2001-03-01 00:00:00

  • Recent advances in cardiac magnetic resonance imaging.

    abstract::Magnetic resonance imaging of the cardiovascular system is now a well-recognized primary investigative technique for many conditions of structural abnormality in clinical cardiology, but the assessment of functional abnormality is also valuable and is increasingly being recognized by clinicians because of the accuracy...

    journal_title:Current opinion in cardiology

    pub_type: 杂志文章,评审

    doi:10.1097/00001573-199611000-00013

    authors: Taylor AM,Pennell DJ

    更新日期:1996-11-01 00:00:00